As Ricœur scholars know, the literature by and on Ricœur is vast. Material written by Ricœur that is not collected in published volumes is often difficult to locate, and even in the published volumes it is frequently a challenge to locate where Ricœur discusses a particular topic. Given the amount of his work it can be a challenge too to determine changes in his analyses over the life of his corpus. And locating secondary literature on Ricœur can be equally problematic. (...) In response, we have been working to establish a model for how Ricœur’s corpus might be digitized so that the issues of access, keyword location, and pattern might all be addressed. To develop the model, we are starting with Ricœur’s primary texts in English and plan to expand over time to other languages and to the secondary literature on Ricœur. In the present article we discuss our model and its five steps: digital access; copyright; text preparation for digital searches and analysis; examples of digital searches and analyses; and an archive portal interface that allows users to query based on an extensible set of search variables without needing to know or access the underlying search logic. We also invite interested researchers to help assist the development of this digitization project. (shrink)

The review system on research with human participants in the Netherlands is characterised as a decentralised controlled and integrated peer review system. It consists of an independent governmental body, the Central Committee on Research Involving Human Subjects (or Central Committee), which regulates the review of research proposals by accredited Medical Research Ethics Committees (MRECs). The legal basis was founded in 1999 with the Medical Research Involving Human Subjects Act. The review system is a decentralised arrangement since most research proposal are (...) reviewed by the 30 accredited MRECs in the country. It is a controlled system in which the Central Committee is responsible for the accreditation and oversight of the MRECs and can make legally binding directives for these committees. The assessment of research proposals is an integrated peer review process in which all documents of the research file are reviewed by experts in one committee only. A small number of research proposals are assessed by the Central Committee and not by accredited MRECs. These proposals are on specific research categories such as gene therapy, cell therapy and embryo research. The review of research with surplus human embryos is regulated separately in the Embryos Act. The Central Committee provides support to the accredited MRECs and to researchers and sponsors. It is currently developing an internet portal to reduce the bureaucracy and make the review process more efficient and transparent. The Central Committee stimulates confidence on medical research in society by providing a public trial registry with core data on reviewed research proposals. (shrink)

During the set-up phase of an international study of genetic influences on outcomes from sepsis, we aimed to characterise potential differences in ethics approval processes and outcomes in participating European countries. Between 2005 and 2007 of the FP6-funded international Genetics Of Sepsis and Septic Shock project, we asked national coordinators to complete a structured survey of research ethic committee approval structures and processes in their countries, and linked these data to outcomes. Survey findings were reconfirmed or modified in 2017. Eighteen (...) countries participated in the study, recruiting 2257 patients from 160 ICUs. National practices differed widely in terms of composition of RECs, procedures and duration of the ethics approval process. Eight countries used a single centralised process for approval, seven required approval by an ethics committee in each participating hospital, and three required both. Outcomes of the application process differed widely between countries because of differences in national legislation, and differed within countries because of interpretation of the ethics of conducting research in patients lacking capacity. The RECs in four countries had no lay representation. The median time from submission to final decision was 1.5 months; in nine approval was received within 1 month; six took over 6 months, and in one 24 months; had all countries been able to match the most efficient approvals processes, an additional 74 months of country or institution-level recruitment would have been available. In three countries, rejection of the application by some local RECs resulted in loss of centres; and one country rejected the application outright. The potential benefits of the single application portal offered by the European Clinical Trials Regulation will not be realised without harmonisation of research ethics committee practices as well as national legislation. (shrink)

BioPortal is a Web portal that provides access to a library of biomedical ontologies and terminologies developed in OWL, RDF(S), OBO format, Protégé frames, and Rich Release Format. BioPortal functionality, driven by a service-oriented architecture, includes the ability to browse, search and visualize ontologies (Figure 1). The Web interface also facilitates community-based participation in the evaluation and evolution of ontology content.

Rita Bottino,1 Santosh Nagaraju,2 Vikas Satyananda,2 Hidetaka Hara,2 Martin Wijkstrom,2 Massimo Trucco,1 David KC Cooper2 1Institute of Cellular Therapeutics, Allegheny Health Network, 2Thomas E Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA: Diabetes mellitus is increasing worldwide. Type 1 diabetes can be treated successfully by islet allotransplantation, the results of which are steadily improving. However, the number of islets that can be obtained from deceased human donors will never be sufficient to cure more than a very (...) small percentage of patients who might benefit from transplantation. Although there are some differences in glucose metabolism between pigs and humans, the use of pigs could provide an unlimited supply of islets, and the insulin produced would undoubtedly control glucose levels. Transplantation of islets into the portal vein results in islets residing in the liver; however, an early inflammatory response and rejection remain problematic, even when the recipient is receiving immunosuppressive therapy. In the long term, immunosuppressive drugs may exhibit toxicities to patients and specifically harm the islet cells. In contrast, encapsulation techniques provide islets with a physical barrier that prevents antibodies binding to the islet graft while still allowing insulin to be released into the recipient's circulation; in theory, patients receiving encapsulated grafts might not require exogenous immunosuppressive therapy. Nonhuman primates with encapsulated pig islet transplants have remained insulin-independent for several weeks, but long-term efficacy remains uncertain. Furthermore, techniques are now available to knock out genes from the pig and/or insert human genes, thus rendering the antigenic structure of pigs closer to that of humans, and providing protection from the human immune response. Islet transplantation from genetically engineered pigs has been followed by insulin independence in a small number of nonhuman primates for greater than 1 year. Neonatal islets have some advantages over adult islets in that they are easier to isolate and culture, and have the ability to proliferate during the first few months after transplantation. In 2009, the International Xenotransplantation Association set up a group to encourage and advise on clinical trials of pig islet xenotransplantation; this group's guidelines are discussed. Clinical trials of encapsulated pig islets are already under way. Keywords: diabetes, islets, pancreatic, pig, xenotransplantation. (shrink)

Maurice Blanchot’s “The Strange and the Stranger” (1958) is an essential text for understanding Blanchot’s thought, its development, and its enduring importance. He presents an early account of the impersonal “neuter” in subject-less experiences like “alienation,” “alteration,” “dispersion,” “disappearance,” and “absence.” These experiences of strangeness threaten thought, which is only “itself and for-itself its own experience.” Relatedly, they also reveal “the neutrality of being or neutrality as being.” With reference to both Emmanuel Levinas and Martin Heidegger, Blanchot clarifies the meaning (...) and exigency of a neuter that can take “upon itself the reality of alienation.”. (shrink)

Terence Irwin's edition of the Nicomachean Ethics offers more aids to the reader than are found in any modern English translation. It includes an Introduction, headings to help the reader follow the argument, explanatory notes on difficult or important passages, and a full glossary explaining Aristotle's technical terms. The Third Edition offers additional revisions of the translation as well as revised and expanded versions of the notes, glossary, and Introduction. Also new is an appendix featuring translated selections from related texts (...) of Aristotle. (shrink)

Corruption is a serious problem in Mexico and the available information regarding the levels of academic dishonesty in Mexico is not very encouraging. Academic integrity is essential in any teaching-learning process focussed on achieving the highest standards of excellence and learning. Promoting and experiencing academic integrity within the university context has a twofold purpose: to achieve the necessary learnings and skills to appropriately perform a specific profession and to develop an ethical perspective which leads to correct decision making. The objective (...) of this study is to explore the relationship between academic integrity and ethical behaviour, particularly workplace behaviour. The study adopts a quantitative, hypothetical and deductive approach. A questionnaire was applied to 1203 college students to gather information regarding the frequency in which they undertake acts of dishonesty in different environments and in regards to the severity they assign to each type of infraction. The results reflect that students who report committing acts against academic integrity also report being involved in dishonest activities in other contexts, and that students who consider academic breaches less serious, report being engaged in academic misconduct more frequently in different contexts. In view of these results, it is unavoidable to reflect on the role that educational institutions and businesses can adopt in the development of programmes to promote a culture of academic integrity which: design educational experiences to foster learning, better prepare students to fully meet their academic obligations, highlight the benefits of doing so, prevent the severity and consequences of dishonest actions, discourage cheating and establish clear and efficient processes to sanction those students who are found responsible for academic breaches. (shrink)

The following is an early, previously untranslated essay by Emmanuel Levinas concerning “the metaphysics of antisemitism.” This essay, published originally in 1938 for Paix et Droit, concerns the shared history and destiny of Jews and Christians, religious groups who maintain a relation of essential “foreignness” to, and so “do not belong” to, the “pagan” world. Levinas distinguishes between the long history of Jewish-Christian antagonism and the newer Nazi-style antisemitism, a particularly insidious “racism” that threatens both Jews and Christians. Levinas calls (...) for a renewed appreciation of the “vocation” common to Jews and Christians to advance Judeo-Christian “solidarity,” a solidarity that Levinas believes is increasingly necessary. (shrink)

France Guwy and Emmanuel Levinas discuss the relationship between “the Bible and philosophy.” Levinas explains that he never “experienced” a contradiction between the two, and that they both aim at the same thing: meaning outside of immanence. Such transcendence, Levinas argues, is impossible for the Spinozist.

ABSTRACT Marcia Sá Cavalcante Schuback’s Time in Exile illuminates being in “gerundive time.” The gerundive tense (which is similar to the infinitive tense in English) captures how our being is always already “suspended” between worlds and meanings—how our being is a “non-final verb.” Schuback considers such existence in the work of Martin Heidegger, Maurice Blanchot, and Clarice Lispector. Of the three thinkers, Lispector’s writing best reveals how existence (especially existence in exile) is an “immense struggle for presence.” Schuback’s hope is (...) that we may find a home in our homelessness. (shrink)

El presente trabajo expone el intento romántico de la interpretación del ánimo épocal, aplicándolo a la misma génesis del romanticismo. Para ello, emn primer lugar, se analiza el caso paradigmáitico de la crísis que significó para Heinrich von Kleist la lectura de las críticas kantianas. Y, luego, se interroga por el verdadero sentido que comporta la "estetización del mundo y lo real" que lleva a cabo el romanticismo temprano, mostrando como esto significa una recuperación de los sentidos (para el sentido) (...) en contra de la razón. (shrink)

El emprendimiento social es visualizado como alternativa para responder a las consecuencias que ha generado el neoliberalismo a nivel mundial. La revisión del concepto, desde una perspectiva axiológica y pragmática, por parte de algunos autores, han demostrado que el emprendimiento social, lejos de ser una alternativa al neoliberalismo es una continuidad del mismo. El presente artículo estudia la relación que tiene el emprendimiento social y el neoliberalismo en función de los elementos ontológicos que lo conforman y las escuelas de pensamiento (...) sobre las que se ha implementado. El resultado muestra las paradojas que presenta el concepto a nivel ontológico, y cómo los emprendimientos sociales desarrollados desde la escuela de Economía Social tienen una mayor capacidad de generar una ruptura con el sistema e ideología neoliberal; mientras que los emprendimientos desarrollados bajo la escuela de innovación social, tienden a generar una continuidad al neoliberalismo.Social entrepreneurship is visualized as an alternative to respond to the consequences generated by neoliberalism worldwide. The review of the concept, from an axiological and practical perspective by several authors, has shown that social entrepreneurship is an alternative to neoliberalism. This article studies the relationship between social entrepreneurship and neoliberalism regarding the ontological elements that make it up and the schools of thought on which it has implemented. The result shows the paradoxes that present the concept at the ontological level, and how the enterprises of the School of Economics have a higher capacity to generate a rupture with the neoliberal system and ideology; while entrepreneurship under the school of social innovation tends to create a continuity to neoliberalism. (shrink)

Abstract:Geodiversity is defined as “the natural range (diversity) of geological (rocks, minerals, fossils), geomorphological (land form, processes) and soil features. It includes their assemblages, relationships, properties, interpretations and systems.” This very physical definition is enlarged by a holistic point of view associated to cultural geomorphology which embraces social and artistic representations of landforms, sometimes considered as a geo-heritage. In this point of view, coal mining memory is symbolized by heap and mine's galleries which are anthropogenic landforms. With abandonment, their appearance (...) has changed through time and in the North of France, the “black gold” became “green gold.” This paper aims to reconstitute the landscape trajectories of these recently rediscovered “coalscapes” and focuses on European coal landscapes, particularly on the Atlantic Front. The studies of the iconography of the National Work Archives compared to present landscapes shows that new heritage statuses focus on picturesque landscape but also reveal an evolution of this model: after having included ecology, (geo)heritage coalscapes make the picturesque model change by taking into account environmental changes, new touristic practices (eco and geo-tourism) and new perceptions of industrial and mining landscapes. In a broader sense, this perception of landscapes refers to the anthropocene times, where human artifacts such as mining features represent human prints on the environment. This paper questions European coal landscape as symbols of migrating landscapes that linked, scientifically and aesthetically, old and modern Europe. (shrink)

Gegenuber den Ansatzen, den fruhen Hegel entweder von den theologischen Jugendschriften her (Dilthey) oder aus seiner Kritik an der Nationalokonomie (Lukacs) zu verstehen, wird diese Arbeit geleitet von der Frage nach dem eigentumlichen philosophischen Interesse, das Hegel von Anfang fuhrte: Religion und Politik in eine Einheit zu bringen.

L’acceptabilité sociale fait référence aux échelons d’acceptation sociale accordée par les communautés et les autres parties prenantes à une entreprise, un projet ou une activité. La SLO est importante pour maintenir le développement économique local ; par conséquent, les entreprises doivent favoriser le développement communautaire et maintenir de bonnes relations avec les communautés pour atteindre leurs objectifs. Certaines études montrent comment des communautés ont obligé des entreprises à arrêter leurs opérations en raison de leurs impacts négatifs, mais dans des pays (...) considérés par Transparency International comme ayant un niveau élevé de corruption, tel le Mexique, ces actions collectives ne sont pas totalement efficaces. Sur la base de sources secondaires, cet article expose les incohérences et les limitations qui existent dans le contexte de l’exploitation minière mexicaine, où les entreprises qui ne disposent pas de SLO obtiennent des résultats différents en fonction de leur proximité avec des groupes politiques et économiques. La présente recherche contribue à l’étude de la SLO dans les pays ayant un niveau élevé de corruption et un système socioéconomique caractérisé par la collusion entre les pratiques des secteurs public et privé. (shrink)

El autor argumenta que el elemento clave que define la existencia de un sistema político democrático es el hecho que la Constitución y las leyes sean el producto de la voluntad mayoritaria del pueblo, expresada en asambleas que lo representen a través de un voto que tenga realmente el mismo valor. Sostiene que para el Chile actual es claro que la Constitución no es el producto de la voluntad mayoritaria del pueblo pues fue impuesta por la dictadura en un plebiscito (...) espurio, y sus contenidos configuran un régimen autoritario. El autor junto con desarrollar estas ideas cuestiona cómo los gobiernos concertacionistas fueron dando por realizada la transición a la democracia. (shrink)

El presente artículo se refiere a la discusión de los autores del así llamado romanticismo temprano con las tesis estéticas de Lessing. En directa vinculación con los movimientos artísticos de finales de siglo XVIII y comienzos del XIX, los hermanos Schlegel se separan de la larga tradición, de procedencia aristotélica, en que la acción creadora es reducida al acto mimético, proponiendo para ello un concepto común de arte que ya no separa a la poética de la plástica, iniciando así, según (...) el autor, la moderna crítica de arte. (shrink)

According to the classical view, beauty is grounded on the universe’s objective harmony, defined by the formula of unity in variety. Concurrently, nature’s beauty is univocal and independent of subjective judgement. In this paper I will argue that, although Leibniz’s view coincides with this formula, his philosophy offers an explanation for subjective dissent in aesthetic judgements about nature. I will show that the acceptance of divergences on aesthetic value are the result of a conception of harmony that includes qualitative variety (...) and dissonance. (shrink)

Ilustración tardía y Proyecto de modernidad -- Ensayos criticos sobre tradición y verdad -- Formación para la tolerancia : la filosofía en escena.

Este artículo expone y discute los principales problemas referidos al status de la Filosofía del espíritu como parte componente del sistema, por un lado, y como realización de la historicidad, por el otro. Dicha polémica exige revisar el estado de la producción hegeliana y sus ediciones, pues se advierte una diferencia textual que, sin duda, influye en la determinación sistemática de la filosofía de Hegel.

Resumen: El artículo busca una comprensión de los trabajos académicos acerca de filosofía de la historia desarrollados por Hegel y Friedrich Schlegel a partir del análisis de lo que considera una disputa constante entre idealismo y romanticismo, en la que se encuentran involucradas tanto la idea de una exposición sistemática inherente a la filosofía en tanto ciencia, como así también el recurso retórico a la ironía y el enfrentamiento confesional de los cristianismos posteriores a la Reforma y su concepto de (...) historia universal.: The article aims to reach an understanding of the scholarly work developed by Hegel and Friedrich Schlegel concerning the Philosophy of History, from the analysis of what is considered as a constant dispute between idealism and romanticism, in which the ideas of a systematic exposition, inherent to philosophy as science, as well as the rhetorical resort to irony and the confessional confrontation of Christianities following the Reformation and its universal history. (shrink)

El artículo busca una comprensión de los trabajos académicos sobre filosofía de la historia desarrollados por Hegel y Friedrich Schlegel a partir del análisis de lo que considera una disputa constante entre idealismo y romanticismo, en la que se encuentran involucradas tanto la idea de una exposición sistemática inherente a la filosofía en tanto ciencia, como así también el recurso retórico a la ironía y el enfrentamiento confesional de los cristianismos posteriores a la Reforma y su concepto de historia universal.

En el presente trabajo se valora la impronta de la perspectiva deconstructiva del mal en/de/por la soberanía, en la obra de Jaques Derrida, para una crítica anti-idolátrica de la democracia. Parte del estudio crítico de dos tradiciones de fundamentación contemporánea de la democracia representativa. El examen de la propuesta de democracia deliberativa de Habermas y de la concepción de radicalización de la democracia de Ernesto Laclau, las cuales permiten evidenciar la reproducción del proceso de formalización de la democracia. Ambas critican (...) al paradigma del conflicto material de clases de origen marxista y responden con una comprensión comunicativa que parte de la centralidad del lenguaje y el discurso como práctica subjetiva consensual. A partir de la reducción del proceso subjetivo a la anterioridad preminente del discurso, la democracia deja de comprender las condiciones materiales de reproducción del sujeto corporal. Marco ante el cual valoramos el papel de la crítica al malestar de la soberanía presente en la obra de Jaques Derrida. El pensamiento derridiano en torno al Malestar de Soberanía critica la reducción de la diferencia desde una constelación categorial y metódica que implica el reconocimiento del conflicto irreductible que representa la emergencia contingencial del otro. La espectralidad como intuición comprensiva permite la afirmación de la responsabilidad ética, como base de toda posición gnoseológica, que pretenda dar condición de posibilidad a un discurso verdadero. Posición que resguarda la posibilidad transformadora del ejercicio de la soberanía a partir de develar sus procesos de represión subjetiva. Esta constelación categorial es sustantiva a una crítica de la reducción de la democracia en tanto ejercicio soberano. (shrink)

Freezers with biospecimen deposits became biobanks and later were networked at the pan-European level in 2013 under the Biobanking and BioMolecular Resources Research Infrastructure—European Research Infrastructure Consortium (BBMRI-ERIC). Drawing on document analysis about the BBMRI-ERIC and multi-sited fieldwork with biobankers in Spain from a science and technology studies approach, we explore what biobanks are expected to do and become under the BBMRI-ERIC framework, and how infrastructural transitions promote particular transformations in biobanking practices. The primary purpose of biobanks in Europe is (...) presented as being to become mediators in contemporary biomedical research (global sharing nodes) distribution, and distributed nodes of samples and their associated data. We argue that infrastructural transitions are complicated and heterogeneous, giving rise to unattended local concerns on adjusting their practices to fit into the BBMRI-ERIC framework, even for non-members, as the case of Spain illustrates, where “old practices” of collection and storage are questioned. In this article, we aim to encourage qualitative studies to explore the lags between pan-European policies and prospects, different contextual interpretations, and biobanking reconfigurations as an opportunity to explore what that lag is made of (e.g. tensions with “old practices,” unresolved conflicts with the national agendas, reservations on a possible centralization of the biobanking practices by regional biobanks, lack of funding, etc.). Such research could enrich not only policy guidance, but also the understanding of technoscientific infrastructures’ scalability. (shrink)

This volume offers a collection of in-depth explorations of pragmatism as a framework for discussions in philosophy of science and metaphysics. Each chapter involves explicit reflection on what it means to be pragmatist, and how to use pragmatism as a guiding framework in addressing topics such as realism, unification, fundamentality, truth, laws, reduction, and more. -/- .

كتاب بحصي يتناول الصراع بين الصوفية والسلفية ويتناول قصة حياة الحلاج وابن الفارض والسهروردي ودواوينهم ويتناول الحب الإلهي عند الصوفية.

"First published by Oxford University Press, 1916."--Title page verso.

An English language translation accompanies the original Greek text of Aristotle's book about the nature of the state, constitutions, revolutions, democracy, and oligarchy.