The intelligent transportation system under the big data environment is the development direction of the future transportation system. It effectively integrates advanced information technology, data communication transmission technology, electronic sensing technology, control technology, and computer technology and applies them to the entire ground transportation management system to establish a real-time, accurate, and efficient comprehensive transportation management system that works on a large scale and in all directions. Intelligent video analysis is an important part of smart transportation. In order to improve (...) the accuracy and time efficiency of video retrieval schemes and recognition schemes, this article firstly proposes a segmentation and key frame extraction method for video behavior recognition, using a multi-time scale dual-stream network to extract video features, improving the efficiency and efficiency of video behavior detection. On this basis, an improved algorithm for vehicle detection based on Faster R-CNN is proposed, and the Faster R-CNN network feature extraction layer is improved by using the principle of residual network, and a hole convolution is added to the network to filter out the redundant features of high-resolution video images to improve the problem of vehicle missed detection in the original algorithm. The experimental results show that the key frame extraction technology combined with the optimized Faster R-CNN algorithm model greatly improves the accuracy of detection and reduces the leakage. The detection rate is satisfactory. (shrink)

The intracellular multiprotein complex β‐catenin destruction complex plays a key role in Wnt/β‐catenin signaling. Wnt stimulation induces the assembly of the receptor‐associated signalosome and the inactivation of the destruction complex, leading to β‐catenin accumulation and transcriptional activation of the target genes. The core components of the destruction complex include Axin, APC, GSK3β, CK1α and other proteins. Recent studies demonstrated that Axin and APC undergo liquid–liquid phase separation (LLPS), which is critical for their function to regulate Wnt/β‐catenin signaling. Here, we discuss (...) the possible roles of LLPS in Wnt/β‐catenin signaling and regulation of Axin LLPS by post‐translational modifications. (shrink)

Precision medicine (PM) aims to revolutionise healthcare, but little is known about the role religion and spirituality might play in the ethical discourse about PM. This Perspective reports the outcomes of a knowledge exchange fora with religious authorities in Singapore about data sharing for PM. While the exchange did not identify any foundational religious objections to PM, ethical concerns were raised about the possibility for private industry to profiteer from social resources and the potential for genetic discrimination by private health (...) insurers. According to religious authorities in Singapore, sharing PM data with private industry will require a clear public benefit and robust data governance that incorporates principles of transparency, accountability and oversight. (shrink)

本书稿以思想札记的形式,广泛涉及儒家思想文化的许多命题和当下思想文化界的思想文化命题,在某种意义和一定程度上以特别的方式对各种论题进行回应和分析批评.

Ben shu fen wu ge zhuan ji,Xuan lu le wang wei guang,Zhang quan jing,Tian xin ming,Liang zhu,Li shen ming,Liu run wei,Zhou xin cheng deng fa biao zai deng qi kan shang de pi pan li shi xu wu zhu yi de wen zhang,Zhi zai yin dao guang da dang yuan gan bu shen ke ren shi li shi xu wu zhu yi de wei hai,Shi zhong jian chi wei wu shi guan,Jian jue fan dui li shi xu wu (...) zhu yi. (shrink)

Ben shu wan zheng di ti xian le yang ming xin xue"xin ji li","zhi xing he yi","zhi liang zhi"san da ming ti,Sheng dong di ji zai le yang ming xin xue li lun zai yang ming shi sheng zhi jian de gou jian he chuan bo guo cheng,Jiao wei ji zhong di zhan xian he hui ji le yang ming de xin xue si xiang ti xi,Dui yu yang ming hou xue de fa zhan chan sheng le zhi jie er (...) shen yuan de ying xiang. (shrink)

Ben shu wei "Song Ming shi qi Chang Jiang zhong you de ru xue yan jiu" cong shu zhi yi: ben cong shu shi ren wen she hui ke xue chong dian yan jiu ji di-Wuhan da xue Zhongguo chuan tong wen hua yan jiu zhong xin tou biao, jing jiao yu bu zu zhi zhuan jia ping shen tong guo, zheng shi pi zhun de jiao yu bu ren wen she hui ke xue 2001 nian du zhong da yan (...) jiu xiang mu, xiang mu pi zhun hao shi 01JAZJD720008, ding yu 2004 nian qian hou wan cheng. ke ti zu zhu chi ren wei Guo Qiyong jiao shou, "Jiangxi zhi xue"shi Zhu Xi ti chu de yi ge gai nian, zhu yao zhi chu zi yu Jiangxi Jinxi Lu shi jia zu yi men de xue shuo, qi nei he shi Lu Jiuyuan de xin xue; di 2 quan ze shi you "Song Yuan xue an" suo zai zhi Xiangshan xiong Zhangfu, Suoshan de xue shuo; di 3 quan wei Xiangshan xiong di de di zi men de si xiang. Ben shu quan mian kao cha Jiangxi zhi xue zai Song dai Chang Jiang zhong you xing qi de xue mo yuan yuan, zhu yao xue shuo, yu Luo xue Min xue Zhejiang zhu xue zhe (Lü Zuqian, Yong Shangsi xian sheng deng) zhi jian de guan xi, yi ji qi dui Wang (Yangming) xue xing qi de nei zai guan lian xing, bing yan ji dui xian dai xin ru xue de tan tao. ben shu de xie zuo jiang zhu zhong si xiang kao gu de fang fa, zai quan mian yan jiu you guan dian ji de ji chu shang, dui you guan ren wu de chu sheng di, huo dong de di qu (ru jia zu suo zai cun luo, xue zhe shu xin wang lai, jiang xue, hui jiang, shu yuan deng) jin xing shi di de kao cha, guang fan di yun yong fang zhi, nian pu, shu yuan zhi, jia pu deng cai liao, ba si xiang jia huan yuan yu ju ti huan jing zhi zhong, zai ju ti she hui de li shi de jia zu de bei jing xia kao cha qi si xiang de nei han, jie shi qi jing shen suo zai, bing jin er yin shen chu qi yi yi yu jia zhi. (shrink)

Guang Yangs Arbeit nimmt die zentrale Frage des heideggerschen Denkens nach dem Wesen des Logos und der Sprache wieder auf, verbindet sie aber mit dem Begriff der Dynamis. So erweist sich der Logos als diejenige Kraft, die zwischen Bewegung und Ruhe vermitteln und damit die Bewegtheit des Seins in sich versammeln kann. Mit dieser in sich gesammelten Kraft hängt auch das Phänomen der Ruhe zusammen, welches die Bewegung auffängt und entsprechend aufgewertet werden muss. Dieser in der Heidegger-Forschung selten beachtete (...) Gedanke der Ruhe deutet auf die privative Dimension des Seins hin, die auch bei Phänomenen wie räumlicher Leere und der Stille zum Tragen kommt und dabei nicht negativ zu fassen ist. In dieser Untersuchung wird zudem - mit und gegen Heidegger - der Möglichkeitscharakter des Seins hervorgehoben, der nicht allein in der vollzugshaften Bewegung aufgeht. (shrink)

Recently, Frauchiger and Renner proposed a Gedankenexperiment, which was claimed to be able to prove that quantum theory cannot consistently describe the use of itself. Here we show that the conclusions of Frauchiger and Renner actually came from their incorrect description of some quantum states. With the correct description there will be no inconsistent results, no matter which quantum interpretation theory is used. Especially, the Copenhagen interpretation can satisfy all the three assumptions,, and of Frauchiger and Renner simultaneously, thus it (...) has no problem consistently describing the use of itself. (shrink)

Ferroptosis, a form of regulated cell death triggered by lipid hydroperoxide accumulation, has an important role in a variety of diseases and pathological conditions, such as cancer. Targeting ferroptosis is emerging as a promising means of therapeutic intervention in cancer treatment. Polyunsaturated fatty acids, reactive oxygen species, and labile iron constitute the major underlying triggers for ferroptosis. Other regulators of ferroptosis have also been discovered recently, among them the mechanistic target of rapamycin complex 1 (mTORC1), a central controller of cell (...) growth and metabolism. Inhibitors of mTORC1 have been used in treating diverse diseases, including cancer. In this review, we discuss recent findings linking mTORC1 to ferroptosis, dissect mechanisms underlying the establishment of mTORC1 as a key ferroptosis modulator, and highlight the potential of co‐targeting mTORC1 and ferroptosis in cancer treatment. This review will provide valuable insights for future investigations of ferroptosis and mTORC1 in fundamental biology and cancer therapy. (shrink)

v. 1. Li ze xue -- v. 2. Yu zhou lun xin li xue -- v. 3 Xing shang xue.

本书从生态文艺的基本观念到历史扫描,进而比较宏观地把握中国美学中的生态思想及中国古代艺术中生态性体验的特点,并由此通过对中国古代美学与艺术的生态特点的认识,通过对其理论及审美转换性的把握而引申至现代, 着力挖掘其现代意义及价值。.

We give a general proof showing that if the evolution from one state to another is not reversible, then the projective measurements on the superposition of these two states are impossible. Applying this no-go result to the Schrödinger’s cat paradox implies that if something is claimed to be a real Schrödinger’s cat, there will be no measurable difference between it and a trivial classical mixture of ordinary cats in any physically implementable process, unless raising the dead becomes reality. Other similar (...) macroscopic quantum superpositions cannot be observed either, due to the lack of non-commuting measurement bases. Our proof does not involve any quantum interpretation theory and hypothesis. (shrink)

本书集中了当今学术界马一浮研究与近现代思想学术史的专家,从各个角度对马一浮学术思想与生平活动予以述介与阐发。.

本书包括两类:一类是从各个不同角度研究王阳明的生平事迹与思想学说,评论其学说宗旨、思想性质与历史影响的论文;另一类则主要是探讨阳明后学各家各派对阳明心学的继承、丰富、修正、扬弃的演变轨迹与思想特色.

Solid-state processing of metal material is a very complex physical and chemical process, which is coupled by a series of variations including heat transfer, momentum transfer, mass transfer, and phase change. Applying three-dimensional finite element numerical method to the simulation of solid-state processing can perform analysis of metal material’s forging processes before production trial production, can obtain their relevant information such as material flow law, temperature field, and strain field under the minimum physical test conditions, thereby predicting metal material’s forming (...) defects and improving their forging quality. On the basis of summarizing and analyzing previous research works, this paper expounded the current status and significance of solid-state processing of metal materials, elaborated the development background, current status, and future challenges of 3D finite element numerical simulation, introduced the discrimination method and free surface solution method of numerical simulation calculation, conducted finite element model’s geometric assumptions, material selection, element division, model establishment, parameter selection, and initial and boundary condition determination, and simulated and analyzed rheological casting, remelting heating, thixoforming, and rotary piercing processes of metal materials. The results show that the 3D finite element numerical method can not only simulate various processes of flow field, temperature field, stress field, and microstructure in solid-state processing but also can provide a reliable basis for effectively obtaining a reasonable description and finding a more optimized design plan for metal material processing in a short time, which plays an important role in understanding and analyzing solid metal forming process, controlling and optimizing process parameters, guiding and mastering rheological casting, and secondary heating and rotary piercing of metal materials. (shrink)