Structure–activity relationship and quantitative SAR are modeling methods largely used in assessing biological properties of chemical substances. QSAR is based on the hypothesis that the chemical structure is responsible for the activity; it follows that similar molecules are expected to have similar properties. Similarity plays an important role in read across, which categorizes molecules primarily on the basis of similarity. Similarity, and chemical similarity too, is a property differently perceived by humans. The various proposed metrics often disagree with human judgment, (...) and no a unique metric for chemical similarity is universally adopted. Researchers argued that categorization is not only explained by similarity but depends as well on abstract knowledge and the task to accomplish. Moreover, similarity cannot be the unique explanation of a categorization, as different perceptual processes take place in category formation. Assuming that similarity judgments are deeply rooted in human knowledge and perception, cognitive sciences contributions are as important as the mathematical considerations of the classical theories. After an excursus in the many views of similarity in philosophy, mathematics, and cognitive science, the paper explores how connectionist systems, which loosely mimic the human cognitive system, could improve similarity-based choices. A case study on building SARs using connectionism and deep neural networks shows the role of similarity in building and explaining those models. A discussion about deep learning for QSAR and as a modeling tool for science concludes the presentation. (shrink)

: In recent years, research on the family role and entrepreneurship has increased extremely, consolidating itself as a valid and current subject of study. However, a part of the scientific literature seems to lack systematization and the boundaries appear unclear, maybe due to its multidisciplinary nature. This paper presents a systematic analysis of academic research, applying bibliometric indicators and cluster analysis, which define the state of research on the international scene. For this purpose, using three well accepted databases among the (...) research community: Scopus, Web of Science, Business Source, a total of 92 articles were selected and analyzed, published between 1989 and 2019 (until March). The results show that this is a relatively recent field of study, with a multidisciplinary character and in which the most influential authors do not coincide with the most productive scientific journals. A cluster analysis finds out five main areas of literature development: the cluster with the largest percentage of co-occurrences (25%) is the one that relates to the dimensions of entrepreneurship, self-employment and personality; in contrast, the area with a lower percentage of co-occurrences of keywords (12,1%) is refers to family business, succession, economic development and Arabia Saudita. Based on the outcome obtained and the shortcomings above, in the final part of the article, possible points of reflection for future research are exposed, which could be useful to further of this field of study. (shrink)

Cet article présente une synthèse du rôle des animaux dans la religion égyptienne en se focalisant tout particulièrement sur le cas des entités hybrides. Alors que l’association avec un ou plusieurs animaux est l’une des caractéristiques des divinités égyptiennes, l’interprétation soulève plusieurs difficultés méthodologiques. Dans la plupart des cas, ces associations sont relativement simples, et mettent en rapport, selon des modalités diverses, un animal avec une divinité ; de telles relations sont alors relativement faciles à identifier et peuvent faire l’objet (...) d’une typologie, en tout cas rudimentaire. Un cas de figure plus complexe est par contre posé par les représentations qui mobilisent non seulement un animal, mais aussi plusieurs motifs iconographiques à la fois. Le présent article commence par identifier les principales formes d’association d’animaux à des divinités, pour ensuite s’interroger plus longuement sur le cas des associations plus complexes, qui sont ici étudiées à partir de deux exemples paradigmatiques : les divinités protectrices et les habitants de la Douat ou monde souterrain. (shrink)

In recent years, the study of women entrepreneurship has experienced great growth, gaining a broad consensus among academics and contributing above all to understanding all those factors that explain the difficulty of women in undertaking an entrepreneurial career. This document tries to contribute to the field of study, thanks to a systematic analysis through the publications present in the topic. For this purpose, 2,848 peer-reviewed articles were analyzed, published between 1950 and 2019, using the Scopus database (SCImago Research Group). Through (...) the use of a series of bibliometric indicators it was possible to define the current state of research on the international scene. The analysis revealed that it is a multidisciplinary field of study and that has started to expand further since 2006, culminating in 2019, which makes it become a current and valid object of study. The analysis of the clusters allowed to isolate 6 different lines of research in which emerged, on the one hand, the importance of entrepreneurial education, social entrepreneurship and the socio-cultural context of reference (e.g. culture, family and institutional support) as tools to overcome the gender gap, on the other, the importance that women entrepreneurship assumes in the economic growth of the country (especially in developing economies), promoting social inclusion and combating poverty and discrimination. The study presents an important contribution to reflect on current policies and to outline future lines of investigation. (shrink)

This volume analyzes and studies how vagueness occurs and matters as a specific problem in the context of theories that are primarily about something else.

The article focuses on Intranet technology as the result of overlapping negotiations among social actors inside organizations. Such negotiations are aimed at establishing and embedding specific relations and representations of work, communication, and learning into the technological artifact. Two case studies are presented to analyze practices and processes of implementation and use of the Intranet. The fieldwork, carried out in two companies in Italy and the United Kingdom, shows how specific contexts and organizational histories can affect such processes. Despite the (...) “optimistic” imagery associated with Intranet technology and the high expectations about its communicative and economic efficiency, the article points out many constraints in the process of implementation and use. Company history and culture, skills and work groups, and use of other technologies and media are relevant factors to account for the current use of the two systems and their low degree of integration into everyday working and communicative practices. (shrink)

Starting from the social construction of technology approach and proposing a literature review of the concept of technological frame, the distinction or continuity between contexts inside and around technology is analyzed as constitutive of a thicker frame. A multilayered articulation of the technological frame is proposed. Organizational history, identity, interorganizational relations, along with discursive practices and communicational routines are seen as the components of the intranet technological frame. Discursive practices, therefore, mediate between macro components belonging to the organizational dimension and (...) micro components concerning the practice of specific organizational communities or workgroups and the inscribed patterns of use through which technology is temporarily stabilized into specific artifacts. The analysis of the frame as set of practices and contexts is carried out by referring to sociotechnical literature and findings of a completed Ph.D. dissertation about intranet technology. (shrink)

Social entrepreneurship, individual activities with a social objective, is used in this study as a conceptual tool for empirically examining farmers’ participation in alternative food networks. This study verifies whether their participation is driven by the social entrepreneurship dimension to satisfy social and environmental needs. We develop a more inclusive view of how social entrepreneurship is present among farmers participating in AFNs by using a behavioural approach based on three main psychological constructs: attitude, objective, and behaviour. The empirical results show (...) that two types of farmers participate in AFNs. One type is closer to commercial entrepreneurs; the main attitudes and objectives affecting their behaviour are oriented toward profit maximization and farm progress. The second type is closer to social entrepreneurial activity; the main objectives affecting their behaviour are oriented towards satisfying social and environmental needs. The study’s results offer implications and suggest recommendations concerning social entrepreneurial practices and the motivations of the farmers who participate in AFNs. (shrink)

We face with the question of a suitable measure theory in Euclidean point-free geometry and we sketch out some possible solutions. The proposed measures, which are positive and invariant with respect to movements, are based on the notion of infinitesimal masses, i.e. masses whose associated supports form a sequence of finer and finer partitions.

Social embeddedness, defined as the interaction of economic activities and social behavior, is used in this study as a conceptual tool to describe the growing phenomenon of food community networks (FCNs). The aim in this paper was to map the system of relations which the FCNs develop both inside and outside the network and, from the number of relations, it was inferred the influence of each FCN upon the formation of new socially embedded economic realities. A particular form of FCN (...) was taken under consideration: solidarity purchase groups (SPGs). Performed with the aid of social network analysis on a sample of SPGs in Sicily (a region in southern Italy), the study allowed us to identify a relational (internal) social embeddedness, in which groups of consumers and farmers are directly influenced by reciprocal interactions, giving rise to more or less numerous links of reciprocity and trust depending on the number of interactions. It was also identified a structural (external) social embeddedness, generated by the nature of relations that the SPGs undertake with the various social actors. From the results of our analysis it emerges that SPGs lie at the intersection of many social realities, influencing them and in turn being influenced by such realities. We highlight the major role played by consumer and environmental associations in affecting the phenomenon of social embeddedness. (shrink)

We explore the notion of a measure in a mereological structure and we deal with the difficulties arising. We show that measure theory on connection spaces is closely related to measure theory on the class of ortholattices and we present an approach akin to Dempster’s and Shafer’s. Finally, the paper contains some suggestions for further research.

The pervasiveness of lying -- Why the lie? The reasons and justifications for lying -- How and why different types of people lie -- Taking the Lie-Q test : learning where you fit -- Everyday social lies -- Lying in public -- Lying at work -- Lying in business -- Lying to friends & relatives -- When men & women lie-the dating game -- Lies with husbands, wives, & intimate others -- The lies of parents & children -- Lying to (...) oneself -- The strategy of deceiving and perceiving (or how to detect when someone is lying) -- Conclusion (or how to deal with different kinds of lies and liars). (shrink)

The Cambridge Companion to Philosophical Methodology offers clear and comprehensive coverage of the main methodological debates and approaches within philosophy. The chapters in this volume approach the question of how to do philosophy from a wide range of perspectives, including conceptual analysis, critical theory, deconstruction, experimental philosophy, hermeneutics, Kantianism, methodological naturalism, phenomenology, and pragmatism. They explore general conceptions of philosophy, centred on the question of what the point of philosophising might be; the method of conceptual analysis and its recent naturalistic (...) critics and competitors; perspectives from continental philosophy; and also a variety of methodological views that belong neither to the mainstream of analytic philosophy, nor to continental philosophy as commonly conceived. Together they will enable readers to grasp an unusually wide range of approaches to methodological debates in philosophy. (shrink)

In this contribution we explore revisionists and anti-revisionists conceptions of the historical imagination. The focus will be on how these conceptions of the historical imagination determine how one ought to answer the question of whether or not it is in principle possible to know the past in its own terms rather than from the perspective of the present. The contrast that we are seeking to draw is that between a conception of the historical imagination which is revisionist in the sense (...) that it is committed to the claim that knowledge of the past is in principle impossible, and one which is anti-revisionist in the sense that it regards knowledge of the past in its own terms to be in principle possible. Revisionism, as we understand it here, is not the contingent claim that in some cases (where, for example, new evidence which was previously unavailable comes to light) the historical understanding of the past may be revised; rather, it represents an a priori claim about the impossibility of knowing the past in its own terms in all cases, and not just in some. Likewise, anti-revisionism, as we understand it here, is the view that historical knowledge is in principle possible; it is not the claim that it is always achieved as a matter of fact. The debate between revisionist and anti-revisionist conceptions of the historical imagination is therefore a second-order debate about the nature of historical knowing, about whether it is possible, and if so, about what its conditions of possibility are. It is not a first order debate about whether or not such knowledge has been achieved in any given case. (shrink)

Material kept in the National Library of Finland shows that from 1963 until 1969 Erik Stenius (1911–1990) worked on a book on antinomies , having been invited by the Dutch logician Evert Beth (1908–1964) to contribute a monograph to the North-Holland series Studies in Logic and the Foundations of Mathematics . The book was never published, but the manuscript has been found, and it is the purpose of this note to report on this finding.

It is our hope that this volume will serve to document both the history of the Collegium Phaenomenologicum during its first ten years as well as some of the philosophical work that has grown out of the annual gatherings in Perugia. The Introduction narrates the history and is supplemented by the Appendices, in which the programs and the participants for each of the ten years are listed. The essays, on the other hand, present in more finished form work that was (...) developed in connection with courses, lectures, or seminars conducted during the first ten years of the Collegium. Giuseppina Moneta John Sallis Jacques Taminiaux Introduction The Collegium Phaenomenologicum in Its First Ten Years GIUSEPPINA C. MONETA The idea of the Collegium Phaenomenologicum first took shape in a conversa tion that I had with Werner Marx at his home in Bollschweil in the Spring of 1975. Previously I had thought of the possibility of a gathering of phenom enologists somewhere in Italy during the summer months. And when I ex plained to Werner Marx that it would not be difficult to find accommodation for such a gathering in a Franciscan monastery in Umbria, he responded enthusiastically and assured me that such a project would have the support of the Husserl Archives in Leuven and in Freiburg. (shrink)

INTRODUCTION The purpose of this essay is to investigate the meaning of the concept of identity within a framework of the phenomenological theory of ...

Humor, laughter, joke telling can be frivolous fun or it could act as a sword and a shield to defend and protect us against life. Humor can, at times, illuminate if not completely explain, some of the irresoluble problems and mysteries that individuals face. And, if all else fails, humor can hold off our fear of the unanswerable and the unacceptable. Historically it can be argued that during times of trial, tribulations, and suffering, Jewish communities and individuals have used humor (...) as a way to cope with and deal with reality. (shrink)

The article aims at integrating the cultural psychology perspective of into the multidisciplinary field of border studies. It analyses the border phenomenon as a co-genetic system. The authors investigate the psychological side of people who relate to the border out of different motives. Then, it expands some of the theoretical concepts current in border studies by introducing psychological dimensions such as intentionality and directionality. Finally, the framework is applied to two case-studies representing the northern and southern European Union frontiers: the (...) case of Estonian officer Eston Kohver in the Setumaa region on the Estonian–Russian border; and the experiences of border guards in the re-bordering process on the Spanish–Moroccan border. It offers an innovative conceptual resource based on a triadic co-genetic epistemological approach, which allows us to overcome the binary oppositions still very present in the contemporary debates in borders studies. (shrink)

Communication as work: we have recently experienced a profound transformation in the processes of production. While the assembly line excluded any form of linguistic productivity, today, there is no production without communication. The new technologies are linguistic machines. This revolution has produced a new kind of worker who is not a specialist but is versatile and infinitely adaptable. If standardized mass production was dominant in the past, today we produce an array of different goods corresponding to specific consumer niches. This (...) is the post-Fordist model described by Christian Marazzi in Capital and Affects. Tracing the development of this new model of labor from Toyota plants in Japan to the most recent innovations, Marazzi's critique goes beyond political economy to encompass issues related to social life, political engagement, democratic institutions, interpersonal relations, and the role of language in liberal democracies.This translation at long last makes Marazzi's first book available to English readers. Capital and Affects stands not only as the foundation to Marazzi's subsequent work, but as foundational work in post-Fordist literature, with an analysis startlingly relevant to today's troubled economic times.This Semiotext edition includes the afterword Marazzi wrote for the 1999 Italian edition. (shrink)

In societies founded on communication, it is increasingly important to think about the formation of subjectivities and of their political function. In this context, a reflection concerning a course given on these themes at the University of Pittsburgh in the Spring of 2004 tries to identify strategies of positive engagement in the contemporary social and political milieu. The presence of writers such as Antonio Negri and Jacques Rancière in a class syllabus will be considered as a contribution to the autonomous (...) and egalitarian formation of the political subject during his/her passage through the American academic system. (shrink)