9 found
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  1. Multiplex parenting: IVG and the generations to come.César Palacios-González, John Harris & Giuseppe Testa - 2014 - Journal of Medical Ethics 40 (11):752-758.
    Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional human gametes could soon be created in vitro. While the ethical debate on the uses of in vitro generated gametes (IVG) was originally constrained by the fact that they could be derived only from embryonic stem cell lines, the advent of somatic cell reprogramming, with the possibility to easily derive human induced pluripotent stem cells from any individual, affords now a major leap in the feasibility of IVG derivation and (...)
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  2. The Identity of Living Beings, Epigenetics, and the Modesty of Philosophy.Giovanni Boniolo & Giuseppe Testa - 2012 - Erkenntnis 76 (2):279-298.
    Two problems related to the biological identity of living beings are faced: the who-problem (which are the biological properties making that living being unique and different from the others?); the persistence-problem (what does it take for a living being to persist from a time to another?). They are discussed inside a molecular biology framework, which shows how epigenetics can be a good ground to provide plausible answers. That is, we propose an empirical solution to the who-problem and to the persistence-problem (...)
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  3.  54
    Ethics and Synthetic Gametes.Giuseppe Testa & John Harris - 2005 - Bioethics 19 (2):146-166.
    The recent in vitro derivation of gamete‐like cells from mouse embryonic stem (mES) cells is a major breakthrough and lays down several challenges, both for the further scientific investigation and for the bioethical and biolegal discourse. We refer here to these cells as gamete‐like (sperm‐like or oocyte‐like, respectively), because at present there is still no evidence that these cells behave fully like bona fide sperm or oocytes, lacking the fundamental proof, i.e. combination with a normally derived gamete of the opposite (...)
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  4.  29
    The European politics of animal experimentation: From Victorian Britain to ‘Stop Vivisection’.Pierre-Luc Germain, Luca Chiapperino & Giuseppe Testa - 2017 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 64:75-87.
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  5.  16
    Rethinking Human Embryo Research Policies.Kirstin R. W. Matthews, Ana S. Iltis, Nuria Gallego Marquez, Daniel S. Wagner, Jason Scott Robert, Inmaculada de Melo-Martín, Marieke Bigg, Sarah Franklin, Soren Holm, Ingrid Metzler, Matteo A. Molè, Jochen Taupitz, Giuseppe Testa & Jeremy Sugarman - 2021 - Hastings Center Report 51 (1):47-51.
    It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...)
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  6.  30
    Reprogramming Potentiality: The Co-Production of Stem Cell Policy and Democracy.Alessandro Blasimme, Bettina Schmietow & Giuseppe Testa - 2013 - American Journal of Bioethics 13 (1):30-32.
  7.  13
    Rethinking Human Embryo Research Policies.Kirstin R. W. Matthews, Ana S. Iltis, Nuria Gallego Marquez, Daniel S. Wagner, Jason Scott Robert, Inmaculada Melo-Martín, Marieke Bigg, Sarah Franklin, Soren Holm, Ingrid Metzler, Matteo A. Molè, Jochen Taupitz, Giuseppe Testa & Jeremy Sugarman - 2021 - Hastings Center Report 51 (1):47-51.
    It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...)
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    The time of timing: How Polycomb proteins regulate neurogenesis.Giuseppe Testa - 2011 - Bioessays 33 (7):519-528.
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    Big Tech platforms in health research: Re-purposing big data governance in light of the General Data Protection Regulation’s research exemption.Ine Van Hoyweghen, Giuseppe Testa & Luca Marelli - 2021 - Big Data and Society 8 (1).
    The emergence of a global industry of digital health platforms operated by Big Tech corporations, and its growing entanglements with academic and pharmaceutical research networks, raise pressing questions on the capacity of current data governance models, regulatory and legal frameworks to safeguard the sustainability of the health research ecosystem. In this article, we direct our attention toward the challenges faced by the European General Data Protection Regulation in regulating the potentially disruptive engagement of Big Tech platforms in health research. The (...)
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