The Istituto e Museo di Storia della Scienza, Florence, Italy, possesses an astrolabe with five latitude plates that is now attributed to the Duisburg workshop of Gerard Mercator. Although it is known that Mercator made instruments, this is the first surviving example to be identified. Another latitude plate is shown to come from the workshop of the Florentine, Giovan Battista Giusti. A seventh plate, possibly engraved by Rumold Mercator, provides the only known Mercatorian polar stereographic projection. The role of (...) Egnazio Danti, cosmographer to the Grand Duke of Tuscany, in the acquisition of the astrolabe in about 1570 is considered. (shrink)

Many individuals with disabling conditions have difficulty with gait and balance control that may result in a fall. Exoskeletons are becoming an increasingly popular technology to aid in walking. Despite being a significant aid in increasing mobility, little attention has been paid to exoskeleton features to mitigate falls. To develop improved exoskeleton stability, quantitative information regarding how a user reacts to postural challenges while wearing the exoskeleton is needed. Assessing the unique responses of individuals to postural perturbations while wearing an (...) exoskeleton provides critical information necessary to effectively accommodate a variety of individual response patterns. This report provides kinematic and neuromuscular data obtained from seven healthy, college-aged individuals during posterior support surface translations with and without wearing a lower limb exoskeleton. A 2-min, static baseline standing trial was also obtained. Outcome measures included a variety of 0 dimensional measures such as center of pressure RMS, peak amplitude, velocities, pathlength, and electromyographic RMS, and peak amplitudes. These measures were obtained during epochs associated with the response to the perturbations: baseline, response, and recovery. T-tests were used to explore potential statistical differences between the exoskeleton and no exoskeleton conditions. Time series waveforms of the COP and EMG data were also analyzed. Statistical parametric mapping was used to evaluate the 1D COP and EMG waveforms obtained during the epochs with and without wearing the exoskeleton. The results indicated that during quiet stance, COP velocity was increased while wearing the exoskeleton, but the magnitude of sway was unchanged. The OD COP measures revealed that wearing the exoskeleton significantly reduced the sway magnitude and velocity in response to the perturbations. There were no systematic effects of wearing the exoskeleton on EMG. SPM analysis revealed that there was a range of individual responses; both behaviorally and among neuromuscular activation patterns. Using both the OD and 1D measures provided a more comprehensive representation of how wearing the exoskeleton impacts the responses to posterior perturbations. This study supports a growing body of evidence that exoskeletons must be personalized to meet the specific capabilities and needs of each individual end-user. (shrink)

The concept of a technical frontier in branches of experimental measurement, such as the resolution of the microscope, angular measure and time telling, has been around for more than 60 years. The purpose of this brief paper is to identify the technical frontier operating on the achromatic astronomical telescope, where a limiting factor of the resolution of fine detail was the quality of the optical glass available. The achromatically corrected objective is formed from two kinds of glass, the common crown (...) glass and the heavy clear flint glass or lead glass. This last was difficult to make homogeneous, that is without regions of different density, and therefore different refraction and dispersion. Unusually, optical glass had to pass a second frontier, this time placed on the whole glass industry by the English Government in the form of excise duty, administered with a bureaucratic efficiency that effectively stopped, in around 1800, the making of optical glass suitable for the serious astronomical telescopes. The result of the tax imposition was to delay the English production of improved optical glass for more than 80 years. (shrink)

The general view is that there is one type of nocturnal, which is universal, first illustrated in a printed book in 1524. Recently, a number of quite differently constructed nocturnals has come to light. Six of these were made at the very beginning of the sixteenth century by Falcono of Bergamo in northern Italy. One of them, with the initials of the inventor, may well be the prototype. Five more are closely similar. Five further nocturnals of the same type have (...) been identified, but they are unsigned, and are not by Falcono. This paper establishes the existence of a hitherto unrecognized Italian workshop, and of a variant type of nocturnal. (shrink)

Citing of previous publications is an important factor in knowledge development. Because of the great amount of publications available, only a selection of studies gets cited, for varying reasons. If the selection of citations is associated with study outcome this is called citation bias. We will study determinants of citation in a broader sense, including e.g. study design, journal impact factor or the funding source of the publication. As a case study we assess which factors drive citation in the human (...) literature on phthalates, specifically the metabolite mono phthalate. A systematic literature search identified all relevant publications on human health effect of MEHP. Data on potential determinants of citation were extracted in duplo. Specialized software was used to create a citation network, including all potential citation pathways. Random effect logistic regression was used to assess whether these determinants influence the likelihood of citation. 112 Publications on MEHP were identified, with 5684 potential citation pathways of which 551 were actual citations. Reporting of a harmful point estimate, journal impact factor, authority of the author, a male corresponding author, research performed in North America and self-citation were positively associated with the likelihood of being cited. In the literature on MEHP, citation is mostly driven by a number of factors that are not related to study outcome. Although the identified determinants do not necessarily give strong indications of bias, it shows selective use of published literature for a variety of reasons. (shrink)

What were Shakespeare's final thoughts on history, tragedy, and comedy? Shakespeare's Last Plays focuses much needed scholarly attention on Shakespeare's "Late Romances." The work--a collection of newly commissioned essays by leading scholars of classical political philosophy and literature--offers careful textual analysis of Pericles, Prince of Tyre, Cymbeline, The Winter's Tale, The Tempest, All is True, and The Two Noble Kinsmen. The essays reveal how Shakespeare's thought in these final works compliments, challenges, fulfills, or transforms previously held conceptions of the playwright (...) and his political-philosophical views. (shrink)

This book assesses how Vatican II opened up the Catholic Church to encounter, dialogue, and engagement with other world religions. Opening with a contribution from the President of the Pontifical Council for Interreligious Dialogue, Cardinal Jean-Louis Tauran, it next explores the impact, relevance, and promise of the Declaration Nostra Aetate before turning to consider how Vatican II in general has influenced interfaith dialogue and the intellectual and comparative study of world religions in the postconciliar decades, as well as the contribution (...) of particular past and present thinkers to the formation of current interreligious and comparative theological methods. Additionally, chapters consider interreligious dialogue vis-à-vis theological anthropology in conciliar documents; openness to the spiritual practices of other faith traditions as a way of encouraging positive interreligious encounter; the role of lay and new ecclesial movements in interreligious dialogue; and the development of Monastic Interreligious Dialogue. Finally, it includes a range of perspectives on the fruits and future of Vatican’s II’s opening to particular faiths such as Judaism, Islam, Hinduism, and Buddhism. (shrink)

Les théories de la connaissance, appelées aussi épistémologies, étudient comment les êtres humains construisent leurs savoirs. Ces disciplines sont plus faciles qu'on ne le croit. En fait, nous avons tous des idées sur ce sujet : des termes comme " prouver, rigueur, observation, percevoir, disciplines, interprétations, savoirs, technologies ", nous sont familiers. D'autres sont moins connus et peuvent faire peur, comme : " paradigme scientifique, représentation, standardisation, idéologie, éthique ". Ce manuel se propose de les apprivoiser par un exposé simple. (...) Il poursuit deux finalités : d'une part, la formation générale personnelle du lecteur ou de la lectrice et, d'autre part, l'acquisition de compétences didactiques. Cet ouvrage intéressera particulièrement les professeurs et étudiants des Hautes Ecoles et des IUFM, les enseignants du secondaire ainsi que les étudiants du 1er cycle universitaire pour un cours d'introduction à la théorie de la connaissance. (shrink)

Transcranial direct current stimulation over the contralateral primary motor cortex of the target muscle has been described to enhance corticospinal excitability, as measured with transcranial magnetic stimulation. Recently, tDCS targeting the brain regions functionally connected to the contralateral primary motor cortex was reported to enhance corticospinal excitability more than conventional tDCS. We compared the effects of motor network tDCS, 2 mA conventional tDCS, and sham tDCS on corticospinal excitability in 21 healthy participants in a randomized, single-blind within-subject study design. We (...) applied tDCS for 12 min and measured corticospinal excitability with TMS before tDCS and at 0, 15, 30, 45, and 60 min after tDCS. Statistical analysis showed that neither motor network tDCS nor conventional tDCS significantly increased corticospinal excitability relative to sham stimulation. Furthermore, the results did not provide evidence for superiority of motor network tDCS over conventional tDCS. Motor network tDCS seems equally susceptible to the sources of intersubject and intrasubject variability previously observed in response to conventional tDCS. (shrink)

À la recherche du temps perdu est une recherche de la vérité produite par la seule écriture romanesque. Le temps est le flux qui traverse ' le réel, l'involontaire et la sensation '. Les affects sont des modes temporels du réel que la sensation involontaire révèle, entre instant et éternité.

A leitura que Hegel faz da antinomia em Kant permite entender que as considerações deste não estão isentas de pressupostos antropológicos e de que, portanto, ele estuda a finitude das categorias nelas mesmas, mas em sua pertinência ao "sujeito", que, no final das contas, é um sujeito "psicológico". Eis o interesse que há em retormar os textos de Hegel para fazer jus à "arte de ler" hegeliana.

Le heurt entre croyances anciennes, découvertes scientifiques et pratiques rationnelles est souvent une guerre dont les victimes se comptent par milliers ou millions : malades mal soignés ou atteints par des épidémies qu'on laisse se ...

This paper presents the algebraic and Kripke modelsoundness and completeness ofa logic over Boolean monoids. An additional axiom added to thelogic will cause the resulting monoid models to be representable as monoidsof relations. A star operator, interpreted as reflexive, transitiveclosure, is conservatively added to the logic. The star operator isa relative modal operator, i.e., one that is defined in terms ofanother modal operator. A further example, relative possibility,of this type of operator is given. A separate axiom,antilogism, added to the logic (...) causes the Kripke models to support acollection of abstract topological uniformities which become concretewhen the Kripke models are dual to monoids of relations. The machineryfor the star operator is shownto be a recasting of Scott-Montague neighborhood models. An interpretationof the Kripke frames and properties thereof is presented in terms ofcertain CMOS transister networks and some circuit transformation equivalences.The worlds of the Kripke frame are wires and the Kripke relation is a specializedCMOS pass transistor network. (shrink)

Defeasible reasoning is concerned with the logics of non-deductive argument. As is described in the literature, the study of this type of reasoning is considerably more involved than the study of deductive argument, even so that, in realistic applications, there is often a lack of resources to perform an exhaustive analysis. It follows that, in a theory of defeasible reasoning, the order and direction in which arguments are developed, i.e. theprocedure, is important. The aim of this article is to show (...) that debate is the most efficient procedure to argue in the presence of limited resources. To do so, there is first some general theory on defeasible argumentation, which is followed by an introduction to the problem of dialectical search. The problem of dialectical search is (or at least, should be) the essential issue in every theory on argumentation, and emerges at every occasion that involves adjudication on competing arguments. Starting with an example, it is explained that dialectical search can be best scheduled according to classical debating techniques, that work along well-tried methods. These methods (which include various forms of curtailment, interruption, and interpretation) have proven their value in keeping debating efforts within reasonable bounds. How they apply in a theory of formal argument, will be shown in this article. (shrink)

Pour sortir des intégrismes et en finir avec la violence.

Philosophy of Communication Ethics is a unique and timely volume that creatively examines communication ethics, philosophy of communication, and "the other.".

This article assumes that the key element in Relativism is the denial of any comparability between different moral codes. Each system of morality is, according to the relativist, defined internally to any given culture, as parallels with examples in sport might illustrate, and as two key examples from recent moral disputes amply show. While classical writers such as Hume and Bentham, each in his way a kind of utilitarian, certainly intended to be absolutist, it might nevertheless be argued that they (...) left the way open to relativism despite their intentions. The absolutist needs to establish a common moral standard of some kind which can be used as a standard of comparison between apparently different moral codes. Hume's assumption that we share the disposition to sympathy with others seems far too optimistic; and Bentham's attempt to be scientific presupposes a shared view both of values and of the canons of moral reasoning; but there is arguably no such shared view. Might some version of Aristotelianism be a more promising approach? The article ends with an ariswer to this question. /// O presente artigo parte do pressuposto de que o elemento-chave do Relativismo é a negação de toda e qualquer comparabilidade entre diferentes códigos morais. Cada sistema de moralidade é, de acordo com o relativista, deftnido internamente nos termos de cada cultura determinada, tal como se pode ilustrar com exemplos do mundo do desporto, e dois exemplos tirados da discussão moral mais recente amplamente demonstram. Enquanto que escritores clássicos tais como David Hume e Jeremy Bentham, cada um deles utilitarista à sua maneira, pretendiam certamente ser absolutistas, a verdade é que, argumenta o autor do artigo, ambos deixaram, apesar das suas intenções, o caminho aberto ao relativismo. O absolutista necessita de alguma forma de estabelecer um padrão moral comum que possa ser usado como termo de comparação entre códigos morais aparentemente diferenciados. O pressuposto de Hume de que nós partilhamos uma inclinação para a simpatia em relação a outros seres humanos parece demasiado optimista; por seu lado, a tentativa de Bentham de corresponder às expectativas da ciência pressupõem, por seu lado, uma visdo comum dos valores e dos cânones do raciocínio moral. O problema, porém, é que se pode demonstrar não existir uma tal visão comum. Assim, pergunta o autor do artigo, não será de considerar uma certa versão do Aristotelismo como uma abordagem mais promissora? A resposta a esta questão constitui a parte final do artigo. (shrink)

BackgroundKnowledge development depends on an unbiased representation of the available evidence. Selective citation may distort this representation. Recently, some controversy emerged regarding the possible impact of swimming on childhood asthma, raising the question about the role of selective citation in this field. Our objective was to assess the occurrence and determinants of selective citation in scientific publications on the relationship between swimming in chlorinated pools and childhood asthma.MethodsWe identified scientific journal articles on this relationship via a systematic literature search. The (...) following factors were taken into account: study outcome (authors’ conclusion, data-based conclusion), other content-related article characteristics (article type, sample size, research quality, specificity), content-unrelated article characteristics (language, publication title, funding source, number of authors, number of affiliations, number of references, journal impact factor), author characteristics (gender, country, affiliation), and citation characteristics (time to citation, authority, self-citation). To assess the impact of these factors on citation, we performed a series of univariate and adjusted random-effects logistic regressions, with potential citation path as unit of analysis.ResultsThirty-six articles were identified in this network, consisting of 570 potential citation paths of which 191 (34%) were realized. There was strong evidence that articles with at least one author in common, cited each other more often than articles that had no common authors (odds ratio (OR) 5.2, 95% confidence interval (CI) 3.1–8.8). Similarly, the chance of being cited was higher for articles that were empirical rather than narrative (OR 4.2, CI 2.6–6.7), that reported a large sample size (OR 5.8, CI 2.9–11.6), and that were written by authors with a high authority within the network (OR 4.1, CI 2.1–8.0). Further, there was some evidence for citation bias: articles that confirmed the relation between swimming and asthma were cited more often (OR 1.8, CI 1.1–2.9), but this finding was not robust.ConclusionsThere is clear evidence of selective citation in this research field, but the evidence for citation bias is not very strong. (shrink)

This volume explores how Catholicism began and continues to open its doors to the wider world and to other confessions in embracing ecumenism, thanks to the vision and legacy of the Second Vatican Council. It explores such themes as the twentieth century context preceding the council; parallels between Vatican II and previous councils; its distinctively pastoral character; the legacy of the council in relation to issues such as church-world dynamics, as well as to ethics, social justice, economic activity. Several chapters (...) discuss the role of women in the church before, during, and since the council. Others discern inculturation in relation to Vatican II. The book also contains a wide and original range of ecumenical considerations of the council, including by and in relation to Free Church, Reformed, Orthodox, and Anglican perspectives. Finally, it considers the Council’s ongoing promise and remaining challenges with regard to ecumenical issues, including a groundbreaking essay on the future of ecumenical dialogue by Cardinal Walter Kasper. (shrink)

It is possible to predict future life forms? In this paper it is argued that the answer to this question may well be positive. As a basis for predictions a rationale is used that is derived from historical data, e.g. from a hierarchical classification that ranks all building block systems, that have evolved so far. This classification is based on specific emergent properties that allow stepwise transitions, from low level building blocks to higher level ones. This paper shows how this (...) hierarchy can be used for predicting future life forms.The extrapolations suggest several future neural network organisms. Major aspects of the structures of these organisms are predicted. The results can be considered of fundamental importance for several reasons. Firstly, assuming that the operator hierarchy is a proper basis for predictions, the result yields insight into the structure of future organisms. Secondly, the predictions are not extrapolations of presently observed trends, but are fully integrated with all historical system transitions in evolution. Thirdly, the extrapolations suggest the structures of intelligences that, one day, will possess more powerful brains than human beings.This study ends with a discussion of possibilities for falsification of the present theory, the implications of the present predictions in relation to recent developments in artificial intelligence and the philosophical implications of the role of humanity in evolution with regard to the creation of future neural network organisms. (shrink)

The amygdala is a key brain area regulating responses to stress and emotional stimuli, so improving our understanding of how it is regulated could offer novel strategies for treating disturbances in emotion regulation. As we review here, a growing body of evidence indicates that the gut microbiota may contribute to a range of amygdala-dependent brain functions from pain sensitivity to social behavior, emotion regulation, and therefore, psychiatric health. In addition, it appears that the microbiota is necessary for normal development of (...) the amygdala at both the structural and functional levels. While further investigations are needed to elucidate the exact mechanisms of microbiota-to-amygdala communication, ultimately, this work raises the intriguing possibility that the gut microbiota may become a viable treatment target in disorders associated with amygdala dysregulation, including visceral pain, post-traumatic stress disorder, and beyond. Also see the video abstract here: https://youtu.be/O5gvxVJjX18 The amygdala plays a central role in regulating many aspects of behavior in rodents and humans, from pain responding to social interaction and psychiatric function. Accumulating evidence suggests microbiota-to-amygdala communication along the gut-brain axis is a key modulator of these amygdala-dependent behaviors, with critical implications for health and disease. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:AN EXPLICATION OF THE DE HEBDOMADIBUS OF BOETHIUS IN THE LlGHT OF ST. THOMAS'S COMMENTARY HE WRITINGS o:f Ancius Manlius Severinus Boehius exercised a powerful influence on the nature and evelopment o:f mediaeval philosophy. The extent of his influence was such that I think it fair to say that anyone seeking more than a superficial grasp of mediaeval philosophy must acquire some first-hand knowledge of his work. The trouble (...) is, however, that while The Corwlsation of Philosophy is well-known and much commented upon, Boethius's other works are relatively neglected.1 Included in this latter group are the five theological tractates, one of which has this imposing title: Quomodo Substantiae In Eo Quad Sint Bonae Sint Cum Non Sint Substantialia Bona. This tractate also has the more managable title De Hebdomadibus and it is as such that I shall refer to it throughout this article.2 I have chosen to give an explication of the De Hebdomadibus for three reasons. First the problem with which it deals (the nature of the relation between goodness and substance) is intrinsically interesting and Boethius's solution to the problem is a model of philosophical analysis. Second, in addition to the fact that the philosophical status of the nine axioms listed in the tractate is a matter of some scholarly controversy, the answer to the obvious question of how these axioms function in the tractate as a whole is not at all clear. And third, this tractate is philosophically significant to those philosophers who take St. 1 I am obliged to Professor Ralph Mcinerny for awakening my interest in Boethius and for his suggestion that the De Hebdomadibus would repay careful study. 2 All references are to the H. F. Stewart and E. K. Rand edition of The Theological Traotates and The Consolation of Philosophy, in the Loeb Classical Library (Cambridge, Massachusetts: Harvard University Press, 1973). 419 420 GERARD CASEY Thomas as their inspiration since it appears that St. Thomas's existence/essence distinction is adumbrated here. I shall begin my explication by giving a brief overview of the main lines of the tractate. Then I shall lay out the arguments contained in the statement and resolution of the dilemma which Boethius constructs, indicating (by means of Roman numerals in parentheses ) where I think particular axioms are meant to apply. Finally, I shall display the axioms as perspicuously as possible and comment on them. Overview The groundplan of the De Hebdomadibus is as follows. It begins with a brief introduction which contains the nine axioms. Then the problem to be considered is outlined in the form of the following dilemma. Things which are are good. This is the basic assumption which will generate the dilemma. Things which are good are so either by virtue of their substance or by participation. If they are good by virtue of their substance then, since God is the only substantial good, we arrive at an impious conclusion: we identify creatures with their Creator. lf they are good by participation then we generate a contradiction : things do and do not tend toward the good. Therefore, the conclusion must be that things which are are not good, which manifestly contradicts the basic assumption. Boethius's solution to the dilemma makes use of a thought-experiment. Abstracting from the first good he distinguishes locutions such as ' to be ' from locutions such as ' to be good.' On the basis of this distinction he is led to conclude that goodness is either a property of things or a principle of things. Re-introducing the notion of the first good, he notes that it is good by virtue of its very being. Secondary goods are also good by virtue of their being but only because that being derives from the will of the first good. Boethius cautions us against likening the being of particular things to the being of the first good and concludes the tractate by considering and refuting two objections to his solution. THE DE HEBDOMADIBUS IN THE LIGHT OF ST. THOMAS 421 The theme of the tractate is the problem of how substances can be good in virtue of their being without, at the same time... (shrink)

Summary Research consists of choosing a problem, proposing and testing problem solutions, and presenting the results. In its central moment — conjectures and testing — science must be autonomous in order to be successful. Securing this autonomy by organizational means is one of the tasks of research policy. Research needs to justify itself only when the researcher makes a claim to the resources of others. To discuss problems of justification of governmental support, it is imperative to distinguish between basic and (...) applied research. In basic research the problem choice is guided only by considerations of scientific interest , while in applied research the problems emanate from extra-scientific concerns since applied research is by definition a means for tackling concrete practical problems. Deciding on external criteria (e.g. deciding whether to support more energy research or more cancer research) is a genuine political problem rather than a problem of research policy. Thus applied research can be justified by referring to the benefit the expected results will yield, but basic research requires a completely different justification. One such justification is the argument that applied research requires a certain overhead in basic research. Securing an adequate balance between funding basic and applied research within the problem area concerned is another task of research policy. (E.g. in the area of cancer whether to support more molecular biology research or more clinical research.) When the overhead argument is not applicable, there still remain several possible justifications for basic research. These are examined in the paper. When setting priorities for basic research within a certain discipline, one apparently must turn to the scientific community itself. It may well be that the researches, who constitute the only expertise available for this task, have to rely on tacit knowledge . If so, this remains afaute de mieux procedure since articulated criteria would be preferable to intuitive procedures. The purpose of methodological reflection on research policy making is to supply intellectual instruments for making the discussion about substantive problems more rational. The substantive problems can be tackled only through the close cooperation of research policy makers and researchers. Thus methodology should not limit the degrees of freedom of either but increase them. (shrink)