OBJECTIVE: To describe the issues faced, and how they were addressed, by the University of Toronto Critical Care Medicine Program/Joint Centre for Bioethics Task Force on Appropriate Use of Life-Sustaining Treatment. The clinical problem addressed by the Task Force was dealing with requests by patients or substitute decision makers for life-sustaining treatment that their healthcare providers believe is inappropriate. DESIGN: Case study. SETTING: The University of Toronto Joint Centre for Bioethics/Critical Care Medicine Program Task Force on Appropriate Use of Life-Sustaining (...) Treatment. PARTICIPANTS: The 24-member Task Force included physician and nursing leaders from five critical care units, bioethicists, a legal scholar, a health administration expert, a social worker, and a hospital public relations professional. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Our specific lessons learned include a) a policy focus on process; b) use of a negotiation and mediation model, rather than a hospital ethics committee model, for this process; and c) the policy development process is itself a negotiation, so we recommend equal involvement of interested groups including patients, families, and the public. CONCLUSIONS: This article describes the key issues faced by the Task Force while developing its policy. It will provide a useful starting point for other groups developing policy on appropriate use of life-sustaining treatment. (shrink)

Recent magnetic resonance imaging and pathological studies have indicated that axonal loss is a major contributor to disease progression in multiple sclerosis. 1 H magnetic resonance spectroscopy, through measurement of N -acetyl aspartate, a neuronal marker, provides a unique tool to investigate this. Patients with primary progressive multiple sclerosis have few lesions on conventional MRI, suggesting that changes in normal appearing white matter, such as axonal loss, may be particularly relevant to disease progression in this group. To test this hypothesis (...) NAWM was studied with MRS, measuring the concentration of N -acetyl derived groups. Single-voxel MRS using a water-suppressed PRESS sequence was carried out in 24 patients with primary progressive multiple sclerosis and in 16 age-matched controls. Ratios of metabolite to creatine concentration were calculated in all subjects, and absolute concentrations were measured in 18 patients and all controls. NA/Cr was significantly lower in NAWM in patients than in controls, as was the absolute concentration of NA. There was no significant difference in the absolute concentration of creatine between the groups. This study supports the hypothesis that axonal loss occurs in NAWM in primary progressive multiple sclerosis and may well be a mechanism for disease progression in this group. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in (...) the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

For historical epistemology to succeed, it must adopt a defensible set of categories to characterise scientific activity over time. In historically orientated philosophy of science during the twentieth century, the original categories of theory and observation were supplemented or replaced by categories like paradigm, research program and research tradition. Underlying all three proposals was talk about conceptual systems and conceptual structures, attributed to individual scientists or to research communities, however there has been little general agreement on the nature of these (...) structures. Recent experimental research in cognitive science has considerably refined the theory of concepts. Drawing upon the results of that research, philosophers can construct more concrete and empirically defensible representations of conceptual systems. I will suggest that this research supports a modest and useful sense of both normal and revolutionary science, not as epistemological continuities or discontinuities, but as particular patterns of conceptual change. (shrink)

Can hybridism about moral claims be made to work? I argue it can if we accept the conventional implicature approach developed in Barker (Analysis 2000). However, this kind of hybrid expressivism is only acceptable if we can make sense of conventional implicature, the kind of meaning carried by operators like ‘even’, ‘but’, etc. Conventional implictures are a form of pragmatic presupposition, which involves an unsaid mode of delivery of content. I argue that we can make sense of conventional implicatures, (...) but doing so requires we embrace a form of pure, non-hybrid expressivism. This is a cognitivist expressivism I have developed elsewhere. We need cognitivist expressivism to make sense of how we evaluate—judge as correct or incorrect—implicature-bearing sentences. Once we embraced the possibility of this pure expressivism, we might as well be pure expressivists about normative discourse too. I show how we can do that. The motivations for a specifically hybrid theory are dialectically undercut. (shrink)

Combining a Nietzschean framework with close attention to a wide range of carefully selected literary texts, Autoaesthetics presents a case for Nietzche's centrality in contemporary aesthetic and literary studies. Based on Nietzche's own practice of combining poetry and philosophy by transcending ressentiment and approaching life to its fullest, Autoaesthetics engages in a heated but intricate debate through and with Nietzche's re-articulation of the self as a strategic (and impossible) aesthetic creation." "Stephen Barker argues that all notions of self are (...) aesthetic, literary, strategic, and teleological, and must be seen not in the context of any essential self but as a complex series of self-articulations. He sets out a strategy of reading that combines Nietzschean "psychology" with subsequent theoretical investigations and shows how Nietzschean dialectics of the self are at work in all (self-defining) human experience in the (post)modern world. His book itself is a play of dialectics (again after Nietzche), designed for interdisciplinary scholars and graduate students interested in exploring the scope of literary and aesthetic theory and philosophy. (shrink)

In a recent paper, Pickel and Rabern (2016) argue that a dynamic Tarskian semantics resolves Fine’s antinomy of the variable without the radical consequences for semantics proposed by Fine (2003, 2007). While Pickel and Rabern’s basic insight—a parameter of discourse context that tracks occurrences of variable-binding expressions—is important, I will argue that their own Tarskian theory faces a destructive dilemma: either their theory does not resolve Fine’s antinomy as they propose, or their theory does not reflect the intuitive motivation for (...) what they call structured meanings. I suggest that in response to this dilemma we should reject one of the principles that generates Pickel and Rabern’s version of the antinomy. Here Pickel and Rabern’s insight has surprising, but salutary, foundational consequences for semantics. (shrink)

A Managerial Philosophy of Technology offers a unique combination of a review of academic work in the philosophy of technology with practical methodologies for business management of technology strategy.

Transcending Subjects: Augustine, Hegel and Theology engages the seminal figures of Hegel and Augustine around the theme of subjectivity, with consideration toward the theology and politics of freedom.

Derided and disregarded by many of his contemporaries, Michel Foucault is now regarded as probably the most influential thinker of the twentieth century, his work is studied across the humanities and social sciences. Reading Foucault, however, can be a challenge, as can writing about him, but in Understanding Foucault, the authors offer an entertaining and informative introduction to his thinking. They cover all the issues Foucault dealt with, including power, knowledge, subjectivity and sexuality and discuss the development of his analysis (...) throughout his work. (shrink)

Tragedy and Citizenship provides a wide-ranging exploration of attitudes toward tragedy and their implications for politics. Derek W. M. Barker reads the history of political thought as a contest between the tragic view of politics that accepts conflict and uncertainty, and an optimistic perspective that sees conflict as self-dissolving. Drawing on Aristotle's political thought, alongside a novel reading of the Antigone that centers on Haemon, its most neglected character, Barker provides contemporary democratic theory with a theory of tragedy. (...) He sees Hegel's philosophy of reconciliation as a critical turning point that results in the elimination of citizenship. By linking Hegel's failure to address the tragic dimensions of politics to Richard Rorty, John Rawls, and Judith Butler, Barkeroffers a major reassessment of contemporary political theory and a fresh perspective on the most urgent challenges facing democratic politics. Derek W. M. Barker is a program officer at the Kettering Foundation. (shrink)

Despite the burgeoning interest in new and more complex accounts of the organism-environment dyad by biologists and philosophers, little attention has been paid in the resulting discussions to the history of these ideas and to their deployment in disciplines outside biology—especially in the social sciences. Even in biology and philosophy, there is a lack of detailed conceptual models of the organism-environment relationship. This volume is designed to fill these lacunae by providing the first multidisciplinary discussion of the topic of organism-environment (...) interaction. It brings together scholars from history, philosophy, psychology, anthropology, medicine, and biology to discuss the common focus of their work: entangled life, or the complex interaction of organisms and environments. (shrink)

A symposium was held at the Centre for Research in the Arts, Social Sciences and Humanities at the University of Cambridge on June 12th 2019, ‘Rethinking Repetition in a Digital Age’, at which Geoff Stead, a leading mobile tech designer, was a keynote speaker. The focus of the Cambridge UK event was on how the potentials of digital technologies—whose harms have received widespread attention—could be redirected for the social good. For Stead, this is precisely what Babbel are doing in (...) their approach to commercial digital language learning. Stead spoke to the idea of reversing our personal relationships to mechanical affordances, and finding empowerment in understanding their designed logics. The transcript of the interview below, made in October 2021, revisits some of the main points he raised at that event. (shrink)

Dismissed as a miserable elitist who condemned popular culture in the name of 'high art', Theodor W. Adorno (1903–1969) is one of the most provocative and important yet least understood of contemporary thinkers. This book challenges this popular image and re-examines Adorno as a utopian philosopher who believed authentic art could save the world. Adorno Reframed is not only a comprehensive introduction to the reader coming to Adorno for the first time, but also an important re-evaluation of this founder of (...) the Frankfurt School. Using a wealth of concrete illustrations from popular culture, Geoffrey Boucher recasts Adorno as a revolutionary whose subversive irony and profoundly historical aesthetics defended the integrity of the individual against social totality. (shrink)

Contextualism in epistemology has traditionally been understood as the view that “know” functions semantically like an indexical term, encoding different contents in contexts with different epistemic standards. But the indexical hypothesis about “know” faces a range of objections. This article explores an alternative version of contextualism on which “know” is a semantically stable term, and the truth-conditional variability in knowledge claims is a matter of pragmatic enrichment. The central idea is that in contexts with stringent epistemic standards, knowledge claims are (...) narrowed: “know” is used in such contexts to make assertions about particularly demanding types of knowledge. The resulting picture captures all of the intuitive data that motivate contextualism while sidestepping the controversial linguistic thesis at its heart. After developing the view, the article shows in detail how it avoids one influential linguistic objection to traditional contextualism concerning indirect speech reports, and then answers an objection concerning the unavailability of certain types of clarification speeches. (shrink)

This paper argues against the view that trolley cases are of little or no relevance to the ethics of automated vehicles. Four arguments for this view are outlined and rejected: the Not Going to Happen Argument, the Moral Difference Argument, the Impossible Deliberation Argument and the Wrong Question Argument. In making clear where these arguments go wrong, a positive account is developed of how trolley cases can inform the ethics of automated vehicles.

Traditional approaches tend to regard figuration (and by extension, deference in general) as an essentially marked or playful use of language, which is associated with a pronounced stylistic effect. For linguistic purposes, however, there is no reason for assigning a special place to deferred uses that are stylistically notable — the sorts of usages that people sometimes qualify with a phrase like "figuratively speaking." There is no important linguistic difference between using redcoat to refer to a British soldier and using (...) suit to refer to a corporate executive (as in "A couple of suits stopped by to talk about the new products"). What creates the stylistic effect of the latter is not the mechanism that generates it, but the marked background assumptions that license it — here, the playful presupposition that.. (shrink)

The phenomenon of systematic polysemy offers a fruitful domain for examining the theoretical differences between lexicological and lexicographic approaches to description. We consider here the process that provides for systematic conversion of count to mass nouns in English (a chicken Æ chicken, an oak Æ oak etc.). From the point of view of lexicology, we argue, standard syntactic and pragmatic tests suggest the phenomenon should be described by means of a single unindividuated transfer function that does not distinguish between interpretations (...) (rabbit = "meat" vs. "fur"). From the point of view of lexicography, however, these pragmatically determined"sense precisions" are made part of explicit description via the inclusion of semantic "licenses," a mechanism distinct from lexical rules. (shrink)

The view that it is better for life to be created free of disability is pervasive in both common sense and philosophy. We cast doubt on this view by focusing on an influential line of thinking that manifests it. That thinking begins with a widely-discussed principle, Procreative Beneficence, and draws conclusions about parental choice and disability. After reconstructing two versions of this argument, we critique the first by exploring the relationship between different understandings of well-being and disability, and the second (...) by more briefly focusing on the idea of a significant reason. By placing these results against the broader historical and ongoing contexts in which the lives of those with disabilities have been deemed of inferior quality, we conclude with a call for greater humility about disability and well-being in thought and practice. (shrink)

Every thinking person wants to lead a life of meaning and purpose. For thousands of years, holy books have told us that such a life is available only through obedience and submission to some higher power. Today, the faithful keep popular devotionals and tracts within easy reach on bedside tables and mobile devices, all communicating this common message: "Life is meaningless without God." In this volume, former pastor Dan Barker eloquently, powerfully, and rationally upends this long-held belief. Offering words (...) of enrichment, emancipation, and inspiration, he reminds us how millions of atheists lead happy, loving, moral, and purpose-filled lives. Practicing what he preaches, he also demonstrates through his own personal journey that life is valuable for its own sake--that meaning and purpose come not from above, but from within. (shrink)

Transitional justice scholars are increasingly concerned with measuring the impact of transitional justice initiatives. Scholars often assume that TJ mechanisms must be properly designed and ordered to achieve lasting effect, but the impact of TJ timing and sequencing has attracted relatively little theoretical or empirical attention. Focusing on Latin America, this article explores variation within the region as to when TJ occurs and the order in which mechanisms are implemented. We utilize qualitative comparative analysis to assess the impact of TJ (...) timing and sequencing on democratic development. We find little evidence for path dependency owing to the chronological order of mechanisms. We do find, however, that amnesties and trials approach a sufficient condition for democratic consolidation in Latin America; trials, however, come closest to being a necessary condition for successful democratic consolidation. (shrink)

Are the sculpture and the mass of gold which permanently makes it up one object or two? In this article, we argue that the monist, who answers ‘one object’, cannot accommodate the asymmetry of material constitution. To say ‘the mass of gold materially constitutes the sculpture, whereas the sculpture does not materially constitute the mass of gold’, the monist must treat ‘materially constitutes’ as an Abelardian predicate, whose denotation is sensitive to the linguistic context in which it appears. We motivate (...) this approach in terms of modal analyses of material constitution, but argue that ultimately it fails. The monist must instead accept a deflationary, symmetrical use of ‘materially constitutes’. We argue that this is a serious cost for her approach. (shrink)

All aspects of the concept of collocation – the phenomenon whereby words naturally tend to occur in the company of a restricted set of other words – are covered in this book. It deals in detail with the history of the word collocation, the concepts associated with it and its use in a linguistic context. The authors show the practical means by which the collocational behavior of words can be explored using illustrative computer programs and examine applications in teaching, lexicography (...) and natural language processing that use collocation in formation. The book investigates the place that collocation occupies in theories of language and provides a thoroughly comprehensive and up-to-date survey of the current position of collocation in language studies and applied linguistics. (shrink)

All over the globe, in both Western and Eastern traditions, philosophers have searched for answers to lifeʼs fundamental questions. Beginning with the Ancient Greeks and Chinese, through the founders of modern philosophy, to modern times, they have inspired legions of followers, some have generated fear, and many have made such an impact as to alter the course of history.\\Discover the life and work of more than 100 philosophers. Find out where and when they lived, review their accomplishments, and understand how (...) they transformed our world.\\An essential guide to 2,500 years of philosophical endeavor. \Learn about ancient philosophy, medieval philosophy, the foundations of modern philosophy, philosophy in Britain and America, Continental philosophy, and Eastern philosophy. \See philosophers in the context of their times.\Includes highlights of each philosopherʼs life and work, and an analysis of their contribution and legacy. (shrink)

This paper discusses the normative structure of principles that require belief-revision in the face of disagreement, the role of self-trust in our epistemic lives, and the tensions that arise between the two. Section 2 argues that revisionary principles of disagreement share a general normative structure such that they prohibit continued reliance upon the practices via which one came to hold the beliefs under dispute. Section 3 describes an affective mode of epistemic self-trust that can be characterised as one’s having an (...) attitude of optimism about the reliability of the practices via which one forms beliefs. The availability of affective self-trust is crucial to being able to rationally resist doubts about those practices. However, as argued in the final section of the paper, following revisionary principles of disagreement can render such trust psychologically unavailable. Consequently, attempts to follow such principles can have doxastic consequences that predictably exceed their normative implications. (shrink)

Discusses the importance of the early history of Greek mathematics to education and civic life through a study of the Parthenon and dialogues of Plato.

Even if our justified beliefs are closed under known entailment, there may still be instances of transmission failure. Transmission failure occurs when P entails Q, but a subject cannot acquire a justified belief that Q by deducing it from P. Paradigm cases of transmission failure involve inferences from mundane beliefs (e.g., that the wall in front of you is red) to the denials of skeptical hypotheses relative to those beliefs (e.g., that the wall in front of you is not white (...) and lit by red lights). According to the Bayesian explanation, transmission failure occurs when (i) the subject’s belief that P is based on E, and (ii) P(Q|E) P(Q). No modifications of the Bayesian explanation are capable of accommodating such cases, so the explanation must be rejected as inadequate. Alternative explanations employing simple subjunctive conditionals are fully capable of capturing all of the paradigm cases, as well as those missed by the Bayesian explanation. (shrink)

The Thousands of Problems for Theorem Provers (TPTP) World is a well-established infrastructure that supports research, development and deployment of automated theorem proving systems. This paper provides an overview of the logic languages of the TPTP World, from classical first-order form (FOF), through typed FOF, up to typed higher-order form, and beyond to non-classical forms. The logic languages are described in a non-technical way and are illustrated with examples using the TPTP language.

Karl Popper is a philosopher of knowledge and politics, rationality and freedom. His ideas have won acceptance and provoked controversy among an academic as well as a more general audience. This book aims to broaden our understanding of Popper's philosophy. It is one of the few studies to present his work as an evolving "system of ideas", and to take account of the full range of his writings. The book discusses Popper's early philosophy of politics, science and social science, as (...) well as his later philosophy, which offers an evolutionary account of human nature and the growth of knowledge. Contrary to many earlier interpretations, Stokes argues that we should look to Popper's political values to understand the unity of his work and the evolution of his theory of knowledge and general philosophy. The chapters in this book examine Popper's arguments, and offer critical analysis of the achievements and shortcomings of his philosophy. In particular, Stokes considers the problems of rationality, politics and ethics in the context of debates between the Frankfurt School of critical theory and critical rationalism. The book will be of interest to second-year undergraduates and above in the fields of philosophy and critical theory. (shrink)

Whether it seems that you know something depends in part upon practical factors. When the stakes are low, it can seem to you that you know that p, but when the stakes go up it'll seem to you that you don't. The apparent sensitivity of knowledge to stakes presents a serious challenge to epistemologists who endorse a stable semantics for knowledge attributions and reject the idea that whether you know something depends on how much is at stake. After arguing that (...) previous attempts to meet this challenge fall short, I offer a new solution: the unassertability account. The account starts with the observation that high stakes subjects aren't in an epistemic position to assert. We generally presuppose that knowing is sufficient for epistemically proper assertion, but this presupposition only stands up to scrutiny if we draw a distinction between two notions of epistemic propriety, and we shouldn't expect ordinary speakers to draw it. A subject in a high stakes situation who fails to draw the distinction will be led by the sufficiency claim to treat anything she isn't in a position to assert as something she isn't in a position to know. The sensitivity of epistemically proper assertion to practical factors explains the merely apparent sensitivity of knowledge to stakes. (shrink)

Demonstratives and Indexicals In the philosophy of language, an indexical is any expression whose content varies from one context of use to another. The standard list of indexicals includes pronouns such as “I”, “you”, “he”, “she”, “it”, “this”, “that”, plus adverbs such as “now”, “then”, “today”, “yesterday”, “here”, and “actually”. Other candidates include the tenses … Continue reading Demonstratives and Indexicals →.

The concept of integration has garnered increased attention in the past few years, despite a long history of only brief mention. Integration services are offered by therapists, coaches, and other practitioners, or may be self-guided. There are many definitions of psychedelic integration, and the term encompasses a range of practices and techniques. This seems to have led to confusion about what integration is and how it is best practiced. The primary focus of this manuscript is the presentation of the first (...) extensive review and concept analysis of definitions, practices, and models of psychedelic integration. We provide a synthesized definition of integration, synthesized model of integration, and comprehensive summary of integration practices to bring clarity to the subject. (shrink)

English ethologist, evolutionary biologist, and writer Richard Dawkins opens Chapter 2 of his bestseller The God Delusion by saying that the God of the Old Testament is "arguably the most unpleasant character in all fiction" and goes on to list nineteen negative character traits. Now in God : the Most Unpleasant Character in All Fiction, Dan Barker, a former ordained minister and current atheist, proves that Dawkins was right."--Jacket.

The use of machine learning systems for decision-support in healthcare may exacerbate health inequalities. However, recent work suggests that algorithms trained on sufficiently diverse datasets could in principle combat health inequalities. One concern about these algorithms is that their performance for patients in traditionally disadvantaged groups exceeds their performance for patients in traditionally advantaged groups. This renders the algorithmic decisions unfair relative to the standard fairness metrics in machine learning. In this paper, we defend the permissible use of affirmative algorithms; (...) that is, algorithms trained on diverse datasets that perform better for traditionally disadvantaged groups. Whilst such algorithmic decisions may be unfair, the fairness of algorithmic decisions is not the appropriate locus of moral evaluation. What matters is the fairness of final decisions, such as diagnoses, resulting from collaboration between clinicians and algorithms. We argue that affirmative algorithms can permissibly be deployed provided the resultant final decisions are fair. (shrink)

In his excellent essay, ‘Nudges in a post-truth world’, Neil Levy argues that ‘nudges to reason’, or nudges which aim to make us more receptive to evidence, are morally permissible. A strong argument against the moral permissibility of nudging is that nudges fail to respect the autonomy of the individuals affected by them. Levy argues that nudges to reason do respect individual autonomy, such that the standard autonomy objection fails against nudges to reason. In this paper, I argue that Levy (...) fails to show that nudges to reason respect individual autonomy. (shrink)

Suppose a driverless car encounters a scenario where harm to at least one person is unavoidable and a choice about how to distribute harms between different persons is required. How should the driverless car be programmed to behave in this situation? I call this the moral design problem. Santoni de Sio defends a legal-philosophical approach to this problem, which aims to bring us to a consensus on the moral design problem despite our disagreements about which moral principles provide the correct (...) account of justified harm. He then articulates an answer to the moral design problem based on the legal doctrine of necessity. In this paper, I argue that Santoni de Sio’s answer to the moral design problem does not achieve the aim of the legal-philosophical approach. This is because his answer relies on moral principles which, at least, utilitarians have reason to reject. I then articulate an alternative reading of the doctrine of necessity, and construct a partial answer to the moral design problem based on this. I argue that utilitarians, contractualists and deontologists can agree on this partial answer, even if they disagree about which moral principles offer the correct account of justified harm. (shrink)

This article holds that governmental investments in quantum technologies speak to the imaginable futures of digital sovereignty and digital infrastructures, two major areas of change driven by related technologies like AI and Big Data, among other things, in international law today. Under intense development today for future interpolation into digital systems that they may alter, quantum technologies occupy a sort of liminal position, rooted in existing assemblages of computational technologies while pointing to new horizons for them. The possibilities they raise (...) are neither certain nor determinate, but active investments in them (legal, political and material investments) offer perspective on digital technology-driven influences on an international legal imagination. In contributing to visions of the future that are guiding ambitions for digital sovereignty and digital infrastructures, quantum technologies condition digital technology-driven changes to international law and legal imagination in the present. Privileging observation and description, I adapt and utilize a diffractive method with the aim to discern what emerges out of the interference among the several related things assembled for this article, including material technologies and legal institutions. In conclusion, I observe ambivalent changes to an international legal imagination, changes which promise transformation but appear nonetheless to reproduce current distributions of power and resources. (shrink)

Alvin Plantinga has argued that evolutionary naturalism (the idea that God does not tinker with evolution) undermines its own rationality. Natural selection is concerned with survival and reproduction, and false beliefs conjoined with complementary motivational drives could serve the same aims as true beliefs. Thus, argues Plantinga, if we believe we evolved naturally, we should not think our beliefs are, on average, likely to be true, including our beliefs in evolution and naturalism. I argue herein that our cognitive faculties are (...) less reliable than we often take them to be, that it is theism which has difficulty explaining the nature of our cognition, that much of our knowledge is not passed through biological evolution but learned and transferred through culture, and that the unreliability of our cognition helps explain the usefulness of science. (shrink)