We have begun work on two separate but related ontologies for the study of neurological diseases. The first, the Neurological Disease Ontology (ND), is intended to provide a set of controlled, logically connected classes to describe the range of neurological diseases and their associated signs and symptoms, assessments, diagnoses, and interventions that are encountered in the course of clinical practice. ND is built as an extension of the Ontology for General Medical Sciences — a high-level candidate OBO Foundry ontology that (...) provides a set of general classes that can be used to describe general aspects of medical science. ND is being built with classes utilizing both textual and axiomatized definitions that describe and formalize the relations between instances of other classes within the ontology itself as well as to external ontologies such as the Gene Ontology, Cell Ontology, Protein Ontology, and Chemical Entities of Biological Interest. In addition, references to similar or associated terms in external ontologies, vocabularies and terminologies are included when possible. Initial work on ND is focused on the areas of Alzheimer’s and other diseases associated with dementia, multiple sclerosis, and stroke and cerebrovascular disease. Extensions to additional groups of neurological diseases are planned. The second ontology, the Neuro-Psychological Testing Ontology (NPT), is intended to provide a set of classes for the annotation of neuropsychological testing data. The intention of this ontology is to allow for the integration of results from a variety of neuropsychological tests that assay similar measures of cognitive functioning. Neuro-psychological testing is an important component in developing the clinical picture used in the diagnosis of patients with a range of neurological diseases, such as Alzheimer’s disease and multiple sclerosis, and following stroke or traumatic brain injury. NPT is being developed as an extension to the Ontology for Biomedical Investigations. (shrink)

The problem -- The text -- Inclinations -- Good -- Nature -- The will -- Ought -- Obligation -- Principles -- Action.

This introduction to the history, philosophy and methodology of human geography explores complex ideas in an intelligible and accessible style. It takes into account the new developments in geographical thought and methods.

This volume celebrates the remarkable career of Dr. Preston King, an African American political philosopher with an international reputation. King's first degree was from Fisk University (1956). He moved directly to the London School of Economics (LSE), completing his M.Sc. (Econ) in 1958 with a Mark of Distinction. He taught at LSE for the next two years. A scrap with Jim Crow America kept him in exile for the next 40 years. Major friends and influences at LSE were Professors Sir (...) Karl Popper, Michael Oakeshott, and Dr Bernard Crick. King took up subsequent lectureships at the Universities of Keele, Ghana, and Sheffield. He was Senior Research Assistant at the Acton Society Trust (London), then professor at the Universities of Nairobi, New South Wales (Sydney), Lancaster, returning at last to the USA as joint Woodruff Professor at Emory and Distinguished Professor at Morehouse. The essays comprising this volume are by internationally renowned figures. They creatively explore History, Toleration, and Friendship, as three seminal themes running through Preston King's sizeable oeuvre. This book's first third consists of essays on Time and History, with brilliant contributions by Professors Browning, Lawson, Moore, and Cherribi. The second third consists of essays on Time and Toleration, with memorable and penetrating analyses by Professors Jones, Read, Modood/Dobbernak, and Brown. The third part consists of essays on Time and Friendship, with offerings - both charming and insightful - by Professors Devere, Smith, and Coleman. The book concludes with a novel and captivating chapter by King himself, on the philosophy of time, which constitutes the substratum of so much of his work and reflection. (shrink)

Sensation -- Skepticism -- Internal senses -- The emotions -- Mechanism -- Materialism and dualism -- Hylomorphism -- The problem of universal knowledge -- Reason -- Immortality -- Freedom -- The will -- Free decision -- Purpose.

This volume outlines a Deleuzian approach to analyzing science, culture and politics.

Ethical decision making is of concern to researchers across all fields. However, researchers typically focus on the biases that may act to undermine ethical decision making. Taking a new approach, this study focused on identifying the most common compensatory strategies that counteract those biases. These strategies were identified using a series of interviews with university researchers in a variety of areas, including biological, physical, social, and health as well as scholarship and the performing arts. Interview transcripts were assessed with two (...) scoring procedures, an expert rating system and computer-assisted qualitative analysis. Although the expert rating system identified Understanding Guidelines, Recognition of Insufficient Information, and Recognizing Boundaries as the most frequently used compensatory strategies across fields, other strategies, Striving for Transparency, Value/norm Assessment, and Following Appropriate Role Models, were identified as most common by the computer-assisted qualitative analyses. Potential reasons for these findings and implications for training and practice are identified and discussed. (shrink)

The increasing interconnectedness of academic research and external industry has left research vulnerable to conflicts of interest. These conflicts have the potential to undermine the integrity of scientific research as well as to threaten public trust in scientific findings. The present effort sought to identify themes in the perspectives of faculty researchers regarding conflicts of interest. Think-aloud interview responses were qualitatively analyzed in an effort to provide insights with regard to appropriate ways to address the threat of conflicts of interest (...) in research. Themes in participant responses included disclosure of conflicts of interest, self-removal from situations where conflict exists, accommodation of conflict, denial of the existence of conflict, and recognition of complexity of situations involving conflicts of interest. Moral disengagement operations are suggested to explain the appearance of each identified theme. In addition, suggestions for best practices regarding addressing conflicts of interest given these themes in faculty perspectives are provided. (shrink)

Introduction to modelling and validation -- Non-hierarchical coloured petri nets -- CPN ML programming -- Formal definition of non-hierarchical coloured petri nets -- Hierarchical coloured petri nets -- Formal defintion of hierarchical coloured petri nets -- State spaces and behavioural properties -- Advanced state space methods -- Formal definition of state spaces and behavioural properties -- Timed coloured petri nets -- Formal definition of timed coloured petri nets -- Simulation-based performance analysis -- Behavioural visualisation -- Examples of industrial applications -- (...) Teaching coloured petri nets. (shrink)

efining Documents in American History: Business Ethics offers an in-depth analysis of 67 primary source documents at the foundation of the study of business ethics. These include letters, newspaper accounts, book excerpts, speeches, political debates, testimony, firsthand accounts, memoirs, court rulings, legal texts, legislative acts, excerpts from both fiction and nonfiction books, and dialogues from dramatic works. More and more, the specific ethics policies that have many businesses and corporations developed in the 1970s and 80s are not enough today. Transparency (...) related to sources and materials, pricing strategies, and the public good are crucial for the success of any business. The material in this two-volume reference work is organized into five sections, and each section begins with a brief introduction that defines questions and problems underlying the subjects addressed in the historical documents. These documents provide an overview of business ethics and how it affects all of society, from the heads of corporations in industries like oil, energy, social media, food, and transportation to the workers that produce the goods and services to the consumers of those goods and services. They present a wide array of legal and moral opinions, descriptions of the effects that business ethics can play in the national and global economy, and they take a closer look at the way that business ethics relates to politics. Each historical document is supported by a critical essay, written by historians and teachers, that includes a Summary Overview, Defining Moment, Author Biography, Document Analysis, and Essential Themes. An important feature of each essay is a close reading of the primary source that develops broader themes, such as the author s rhetorical purpose, social or class position, point of view, and other relevant issues. Each essay also includes a Bibliography and Additional Reading section for further research. The detailed document analysis begins with early essays instrumental in the creation and development of the field of business ethics and continues to 2019 by examining issues relevant right now, from harassment and discrimination to technology and privacy. This two-volume set includes in-depth chapters that provide a thorough commentary of significant primary source documents. -- Amazon.com. (shrink)

Research misconduct is of growing concern within the scientific community. As a result, organizations must identify effective approaches to training for ethics in research. Previous research has suggested that biases and compensatory strategies may represent important influences on the ethical decision-making process. The present effort investigated a training intervention targeting these variables. The results of the intervention are presented, as well as a description of accompanying exercises tapping self-reflection, sensemaking, and forecasting and their differential effectiveness on transfer to an ethical (...) decision-making task. (shrink)

Den daarlige Darwinisme.--Om kommunisme.--Udviklingen og kunsten.--Ungdomsevangeliet.--Darwinismen defineret.--Opdragelsen.--Overbefolkningen.--Race og udvælgelse.--Slægtsarkivet.

The enigma of an evil will -- The order of actions to the ultimate end -- The satisfaction of desire -- Venial sin -- The first moral act -- The shared good -- Sins of passion -- Weakness of will -- Sins from an evil will -- Sins of ignorance -- Omissions -- The first cause of moral evil -- Compatibilism or libertarianism -- Free decision -- Choose life.

Agent Relative Ethics asks what the world would look like if we adopted agent relativity wholeheartedly, clinging to no shred of absolute morality. Alastair MacIntyre's haunting image of a post-apocalyptic world, in which our knowledge of ethics has been fragmented, poses a contrast between modern morality and ancient ethics. The two stand divided along the fault line of the nature of the good. Modern ethics has placed its stake in the absolute good, while ancient ethics rests upon the foundation of (...) the relative good. Following the lead of Bernard Williams, Agent Relative Ethics identifies alienation as a disturbing symptom of the present focus upon absolute goods. It then completes the diagnosis of the malady afflicting modern moral theory by clarifying the difference between absolute and relative goods. The remainder of the book explores how agent relativity can overcome the modern fragmentation of our ethical knowledge. Not just any relative goods can rectify the modern disorder. Only shared goods, belonging to a union of individuals, are sufficiently robust to overthrow the contemporary despotism of neutral goods. These shared goods exhibit many parallels with common sense morality, including partiality, impartiality, punishment, and an antagonism toward harmfully using others together with a more lenient attitude toward foreseeing harm. The final chapters probe the conditions, often unpalatable to the modern mind, by which ethics might be restored. Agent Relative Ethics will be of interest to scholars and advanced students working in ethics and moral theory, ancient ethics, and the history of philosophy. (shrink)

Ecosystems, the human brain, ant colonies, and economic networks are all complex systems displaying collective behaviour, or emergence, beyond the sum of their parts. Complexity science is the systematic investigation of these emergent phenomena, and stretches across disciplines, from physics and mathematics, to biological and social sciences. This introductory textbook provides detailed coverage of this rapidly growing field, accommodating readers from a variety of backgrounds, and with varying levels of mathematical skill. Part I presents the underlying principles of complexity science, (...) to ensure students have a solid understanding of the conceptual framework. The second part introduces the key mathematical tools central to complexity science, gradually developing the mathematical formalism, with more advanced material provided in boxes. A broad range of end of chapter problems and extended projects offer opportunities for homework assignments and student research projects, with solutions available to instructors online. Key terms are highlighted in bold and listed in a glossary for easy reference, while annotated reading lists offer the option for extended reading and research. (shrink)

Some recent views of action have claimed that a correct conceptual account of action must include second-order motivational states. This follows from the fact that first-order motivational states such as desires account for action or mere behavior in which the agent's participation is lacking; thus, first-order motivational states cannot by themselves account for action in which the agent participates, so-called full-blooded action. I argue that representing the agent's participation by means of second-order states is bound to fail because it misrepresents (...) what an agent is doing when acting in the full-blooded sense. I begin by characterizing full-blooded action and explaining the failure of first-order accounts to explain it. I next show that while second-order accounts have some success in explaining full-blooded action, they fail to distinguish it from action which exhibits motivational alienation. I then argue that even if this problem were resolved, the second-order accounts more fundamentally misrepresent full-blooded action by depicting such action in an introverted manner. I conclude by considering a sketch of agency and full-blooded action that does not rely on second-order states and by addressing a primary concern thought to favor the second-order accounts, the concern of agent causation. (shrink)

Since the 1980s the concept of ANT has remained unsettled. ANT has continuously been critiqued and hailed, ridiculed and praised. It is still an open question whether ANT should be considered a theory or a method or whether ANT is better understood as entailing the dissolution of such modern ‘‘genres’’. In this paper the authors engage with some important reflections by John Law and Bruno Latour in order to analyze what it means to ‘‘do ANT,’’ and, doing so after ‘‘doing (...) ANT on ANT.’’ In particular the authors examine two post-ANT case studies by Annemarie Mol and Marilyn Strathern and outline the notions of complexity, multiplicity, and fractality. The purpose is to illustrate the analytical consequences of thinking with post-ANT. The analysis offers insights into how it is possible to ‘‘go beyond ANT,’’ without leaving it entirely behind. (shrink)

Ideen om et videnskabsteoretisk sygdomsbegreb peger på følgende generalisering. Sygdomme er modsigelser imellem biologiske og sociale fænomener. Det centrale ved sygdomme er, at de både er forandringer og skader i biologiske systemer og indskrænkninger i handlemuligheder. Dette synspunkt medfører selvfølgelig at sygdomme hverken er naturbegivenheder, sociale normer eller kontroller, og ej heller en særlig del af virkeligheden vi kunne kalde den patolo- giske del. Sygdomme lokaliseres på vores konceptuelle kort som mod- sigelser imellem det biologiske og det sociale. Det fremstillede (...) begreb benægter altså muligheden af en reduktion til det rent bio- logiske eller rent sociologiske, idet sygdom netop opfattes som en modsigelse imellem disse. (shrink)

Thomas Nagel recognizes that it is commonly believed that people can neither be held morally responsible nor morally assessed for what is beyond their control. Yet he is convinced that although such a belief may be intuitively plausible, upon reflection we find that we do make moral assessments of persons in a large number of cases in which such assessments depend on factors not under their control. Of such factors he says: (p. 26).

In this impassioned polemic, radical environmental philosopher Derrick Jensen debunks the near-universal belief in a hierarchy of nature and the superiority of humans. Vast and underappreciated complexities of nonhuman life are explored in detail--from the cultures of pigs and prairie dogs, to the creative use of tools by elephants and fish, to the acumen of caterpillars and fungi. The paralysis of the scientific establishment on moral and ethical issues is confronted and a radical new framework for assessing the intelligence (...) and sentience of nonhuman life is put forth. Jensen attacks mainstream environmental journalism, which too often limits discussions to how ecological changes affect humans or the economy--with little or no regard for nonhuman life. With his signature compassionate logic, he argues that when we separate ourselves from the rest of nature, we in fact orient ourselves against nature, taking an unjust and, in the long run, impossible position. Jensen expresses profound disdain for the human industrial complex and its ecological excesses, contending that it is based on the systematic exploitation of the earth. Page by page, Jensen, who has been called the philosopher-poet of the environmental movement, demonstrates his deep appreciation of the natural world in all its intimacy, and sounds an urgent call for its liberation from human domination. (shrink)

Increasing interest in applying the theory and practice of deliberative democracy to new and varied political contexts leads us to ask whether or not deliberation is a universal political practice. While deliberation does manifest a universal competence, its character varies substantially across time and space, a variation partially explicable in cultural terms. We deploy an intersubjective conception of culture in order to explore these differences. Culture meets deliberation where publicly accessible meanings, symbols, and norms shape the way political actors engage (...) one another in discourse. Fuller understanding of political deliberation requires comparative and historical studies of particular contexts. We look at one case from Egypt in some depth and provide shorter illustrations from Botswana, Europe, India, Japan, Madagascar, the United States, Yemen, and elsewhere. Cross-cultural learning can enrich the theory of deliberative democracy, and give democratic theory a more universal reach. (shrink)

Aquinas talks about a topic with which fans of Sons of Anarchy are all too familiar: homicide and murder. For Aquinas, murder is the private, intentional homicide of an innocent human being and always wrong. This is called the Murder Principle. Murder is the killing of an innocent. This seems to leave the Sons—a private organization rather than an arm of the state—without the legitimate authority to take a life. Watching Sons of Anarchy makes us increasingly suspicious of the moral (...) authority of the state and its agents, who hardly seem like the competent “doctors” of Aquinas's amputation analogy. Contemporary philosophers have articulated the Doctrine of Double Effect (DDE), the gist of which states that it is sometimes morally permissible to bring about as a foreseen but unintended side‐effect what one would not be permitted to bring about intentionally. Aquinas's Murder Principle condemns much of what the Sons do. (shrink)

This chapter contains section titled: Should We Stay or Should We Go Now? Frak the Numbers! Saving Starbuck? The Mark of Cain “Evil Men in the Gardens of Paradise?” Sacrifice Notes.

This chapter contains sections titled: Identity Transitions Connection or Alienation? “I want to be involved” Rites of Passage Daddy at Last Postscript Notes.

In the early days, before Superman's full array of superpowers “developed,” Clark Kent's reporter persona was necessary for gathering information. Although he was pretty tough and fast, Superman didn't yet have the flight, the super‐hearing, the super‐vision, or the super‐intelligence that he would later have. The strategies that explain why a mere mortal or even a Golden Age Superman might not be up to meeting the demands of the S‐principle full time won’t apply to today's Superman. We may face a (...) choice: either we say goodbye to Clark or we abandon the S‐Principle. Clark Kent and Superman: We've had glimpses of worlds in which one exists without the other. But they're both normally there, and occasionally at odds. Jor‐El wants Superman to embrace his destiny as Earth's savior, Martha wants Clark to find a life for himself, and Lex wants Superman to leave and let humanity find its own path. (shrink)

In Beyond Rationality: Contemporary Issues, scholars from a variety of disciplines explore the concept of "irrationality" in today's increasingly complex world. Combining both theory and practice, this is essential reading for anyone wishing to understand such diverse puzzles as why citizens often readily support dictatorships, how terrorists "reason," and why seemingly rational people often make irrational choices.