Computationalism is the claim that all possible thoughts are computations, i.e. executions of algorithms. The aim of the paper is to show that if intentionality is semantically clear, in a way defined in the paper, then computationalism must be false. Using a convenient version of the phenomenological relation of intentionality and a diagonalization device inspired by Thomson's theorem of 1962, we show there exists a thought that cannot be a computation.

Education aims at more than supplying learners with information, or knowledge of facts. Even when the transmission of information is at stake, abilities relevant to using that information are among the things that teachers aim, or ought to aim, to inculcate. We may think that abilities for critical reflection on knowledge, and critical thinking more generally, are central to what teachers should cultivate in their students. Moreover, we may hope that students acquire not merely the ability to (e.g.) think critically, (...) but the propensity or habit of doing so. We hope that critical thinking will be something they *do* do, not something they merely *can* do; that they will become, not merely capable of inquiry, but inquisitive; and so on. If education aims at more than the inculcation of propositional knowledge, are these other aims non-cognitive, or non-epistemic? This essay aims to make progress on this question by critically examining Gilbert Ryle's conceptions of skill and habit. (shrink)

The idea underlying this article was that the humanities in general and business ethics in particular should be more firmly embedded in business management programs. A number of areas have been identified for students to use as topics for research projects in management ethics. These ranged from Biblical and classical times to the present day. Some were drawn from sources that were less well known e.g. the De consolatione philosphiae ‘The Consolation of Philosophy’ by Boethius 524 AD. This was chosen (...) partly for its ethical content, but also because Boethius was magister officiorum i.e. head of the civil service. Aelfred the Great (849–899) King of Wessex (he who burnt those cakes) was chosen because he promoted the intellectual, moral and spiritual qualities that were to serve as guidelines for his executives. Nineteenth century literature (Dickens, Thackeray, Trollope and Galsworthy) was also chosen as a source of topics for research projects in business ethics. The writer acknowledges the work of earlier writers in the fields of management, organisation theory, and business ethics. (shrink)

Most donated organs in the United States come from brain dead donors, while a small percentage come from patients who die in “controlled,” or expected, circumstances, typically after the family or surrogate makes a decision to withdraw life support. The number of organs available for transplant could be substantially if donations were permitted in “uncontrolled” circumstances–that is, from people who die unexpectedly, often outside the hospital. According to projections from the Institute of Medicine, establishing programs permitting “uncontrolled donation after (...) circulatory determination of death,” or uDCDD, throughout the United States has the potential to provide 22,000 more donation opportunities annually. In contrast, U.S. controlled donation after circulatory determination of death, or cDCDD, cases have increased progressively over the past decade from 87 to 848 donors, but currently account for only 10.6 percent of all deceased donors. Following the IOM recommendations, several projects exploring the feasibility of uDCDD were funded by the federal government, including a grant from the Health Resources and Services Administration that supported a pilot project in New York City in which the authors of this article participated.A key feature of our protocol, and indeed of many uDCDD protocols, is the initiation of preservation methods such as chest compressions and extracorporeal membrane oxygenation shortly after death in order to perfuse and preserve the donor's organs. Critics of uDCDD argue that the means of determining death deviates from generally ascribed principles. They assert that reinstituting circulation in order to preserve organs has the effect of “undoing” the prior determination of death. The result is that cDCDD is widely accepted and practiced routinely even though it only marginally increases the number of organs available for transplantation, and uDCDD is widely considered unacceptable despite being ethically embraced and proven to significantly increase organ donation opportunities in other countries. This article explores the evolution of this counterintuitive state of affairs and calls for a policy that, in line with the IOM report, allows for both cDCDD and uDCDD protocols. (shrink)

The interactions between literature and science and between literature and psychoanalysis have been among the most thriving areas for interdisciplinary study in recent years. Work in these 'open fields' has taught us to recognize the interdependence of different cultures of knowledge and experience, revealing the multiple ways in which science, literature, and psychoanalysis have been mutually enabling and defining, as well as corrective and contestatory of each other. Inspired by Gillian Beer's path-breaking work on literature and science, this volume presents (...) fourteen new essays by leading American and British writers. They focus on the evolutionary sciences in the nineteeth-century; the early years of psychoanalysis, from Freud to Ella Freeman Sharpe; and the modern development of the physical sciences. Drawing on recent debates within the history of science, psychoanalytic literary criticism, intellectual history, and gender studies, the volume makes a major contribution to our understanding of the formation of knowledge. Among its recurrent themes are: curiosity and epistemology; 'growth', 'maturity', and 'coming of age' as structuring metaphors ; taxonomy; sleep and dreaming and elusive knowledge; the physiology of truth; and the gender politics of scientific theory and practice. The essays also reflect Beer's extensive influence as a literary critic, with close readings of works by Charlotte Brontë, Alfred Lord Tennyson, George Eliot, Thomas Hardy, Henry James, Oscar Wilde, H. G. Wells, Edith Ayrton Zangwill, Charlotte Haldane, Virginia Woolf, George Orwell, and Karin Boye. (shrink)

The interactions between literature and science and between literature and psychoanalysis have been among the most thriving areas for interdisciplinary study in recent years. Work in these 'open fields' has taught us to recognize the interdependence of different cultures of knowledge and experience, revealing the multiple ways in which science, literature, and psychoanalysis have been mutually enabling and defining, as well as corrective and contestatory of each other. Inspired by Gillian Beer's path-breaking work on literature and science, this volume presents (...) fourteen new essays by leading American and British writers. They focus on the evolutionary sciences in the nineteeth-century; the early years of psychoanalysis, from Freud to Ella Freeman Sharpe; and the modern development of the physical sciences. Drawing on recent debates within the history of science, psychoanalytic literary criticism, intellectual history, and gender studies, the volume makes a major contribution to our understanding of the formation of knowledge. Among its recurrent themes are: curiosity and epistemology; 'growth', 'maturity', and 'coming of age' as structuring metaphors ; taxonomy; sleep and dreaming and elusive knowledge; the physiology of truth; and the gender politics of scientific theory and practice. The essays also reflect Beer's extensive influence as a literary critic, with close readings of works by Charlotte Brontë, Alfred Lord Tennyson, George Eliot, Thomas Hardy, Henry James, Oscar Wilde, H. G. Wells, Edith Ayrton Zangwill, Charlotte Haldane, Virginia Woolf, George Orwell, and Karin Boye. (shrink)

Unexpected discoveries in nonequilibrium physics and nonlinear dynamics are changing our understanding of complex phenomena. Recent research has revealed fundamental new properties of matter in far-from-equilibrium conditions, and the prevalence of instability-where small changes in initial conditions may lead to amplified effects.

Health disparities education is an integral and required part of medical professional training, and yet existing curricula often fail to effectively denaturalize injustice or empower learners to advocate for change. We discuss a novel collaborative intervention that weds the health humanities to the field of health equity. We draw from the health humanities an intentional focus retraining provider imaginations by centering patient narratives; from the field of health equity, we draw the linkage between stigmatized social identities and health disparities. We (...) describe a longitudinal health equity curriculum for the Hospice and Palliative Medicine fellowship in Memphis, Tennessee, to give trainees exposure to the concept of structural violence and how it affects clinical care. The curriculum was developed in partnership with humanities and social sciences faculty who staff a Health Equity academic program at a small liberal arts college in Memphis. This curriculum has been implemented for the past four years in support of 22 hospice and palliative medicine fellows. Group debriefs and a mixed methods survey have revealed widespread and lasting impact towards understanding health equity concepts, enhanced communication and treatment of patients, and empowerment to address the broader needs and policies affecting patients and the communities in which they live. Ultimately, we model an educational initiative that integrates equity across the full scope of healthcare practice and equips learners with skills for sustaining compassionate practices, focusing on equity-oriented, person-centered care across the full scope of healthcare practice. (shrink)

The present collection of translations arises from our work within Writing Urban Places, a network of researchers interested in the different ways citizens appropriate meaningful built environments through stories, and in doing so are also better able to integrate with others. A key locus in this respect is what our network has termed the ‘mid-sized’ [or ‘intermediate’] European city. Often afforded only cursory attention in the discussion of both culture and society, overlooked in favour of more usual suspects, such urban (...) places allow for a more de-centred, and on occasions regionally focused, view of urban practices, even as they play host to a significant element of contemporary European life and experience. The quest for meaningfulness and appropriation of the urban environment through co-creative, adaptive, and transformative processes (many of which have a textual quality) became central to the theoretical framework of this initiative. Between the individual places in which such processes could be observed and documented, we hypothesized, arises the problem of intermediation – the move from place to place, and its techniques. Translation, more than a textual practice among others, emerged as a structuring consideration of the project at a European scale. Other Destinations is the outcome of this collective process presented here, offering entry into this work to an English-language readership for the first time. We hope that, even as they bring their cities of origin somewhat closer to a new readership, those readers will be uprooted and moved some distance in the direction of these ‘other destinations.’ -/- The edited volume Other Destinations. Translating the Mid-sized European City thus features English translations of 15 21st century (mainly) literary texts published in different media (books, podcasts, journals, online/social media) originally written in languages other than English and that have not previously been translated into English. The selected texts cover the topic of mid-sized European cities, where mid-sized does not solely refer to the size in terms of geographical scope or the number of inhabitants, but also to their socio-historical context of urban identity where these cities are neither metropolises nor small towns, but “other”, lesser-known European cities. The texts selected to be translated in this edited volume cover cities like Volos, Canakkale, Varna, Plovdiv, Durres, Tirana, Porto, Den Haag, Osijek, Salzburg, Naples, Zrenjanin, Loule and others…. The publication intends to enhance the dissemination and accessibility to an international readership of texts about overlooked urban contexts, “other”, lesser-known European cities, their stories and signifying practices in order to develop a better awareness of these cities, their self-constructions, and their responses to the challenges of the present. (shrink)

Why do we watch and like horror films? Despite a century of horror film-making and en-tertainment, little research has examined the human motivation to watch fictional horror and how horror film influences individuals’ behavioural, cognitive and emotional re-sponses. This review provides the first synthesis of the empirical literature on the psy-chology of horror film using multi-disciplinary research from psychology, psychotherapy, communication studies, development studies, clinical psychology, and media studies. The paper considers the motivations for people’s decision to watch horror, why (...) people enjoy horror, how individual differences influence responses to, and preference for, hor-ror film, how exposure to horror film changes behaviour, how horror film is designed to achieve its effects, why we fear and why we fear specific classes of stimuli, and how lik-ing for horror develops during childhood and adolescence. The literature suggests that (1) low empathy and fearfulness are associated with more enjoyment and desire to watch horror film but that specific dimensions of empathy are better predictors of people’s re-sponses than are others; (2) there is a positive relationship between sensation-seeking and horror enjoyment/preference but this relationship is not consistent; (3) men and boys prefer to watch, enjoy and seek our horror more than do women and girls; (4) women are more prone to disgust sensitivity or anxiety than are men and this may mediate the sex difference in the enjoyment of horror; (5) younger children are afraid of symbolic stimuli whereas older children become afraid of concrete or realistic stimuli; (6) in terms of coping with horror, physical coping strategies are more successful in younger children; priming with information about the feared object reduces fear and increases children’s enjoyment of frightening television and film. A number of limitations in the literature are identified, including the multifarious range of horror stimuli used in studies, disparities in methods, small sample sizes, and a lack of research on cross-cultural differences and similarities. Ideas for future research are explored. (shrink)

Although nature of science and nature of scientific inquiry are related to each other, they are differentiated as NOS is being more related to the product of scientific inquiry which is scientific knowledge whereas NOSI is more related to the process of SI. Lederman et al. determined eight NOSI aspects for K-16 context. In this study, a science camp was conducted to teach scientific inquiry and NOSI to 24 6th and 7th graders. The core of the program was guided inquiry (...) in nature. The children working in small groups under guidance of science advisors conducted four guided-inquiries in the nature in morning sessions on nearby plants, animals, water, and soil. NOSI aspects were made explicit during and at the end of each inquiry session. Views about scientific inquiry questionnaire was applied as pre- and post-test. The results of the study showed that children developed in all eight NOSI aspects, but higher developments were observed in “scientific investigations all begin with a question” and “there is no single scientific method,” and “explanations are developed from data and what is already known” aspects. It was concluded that the science camp program was effective in teaching NOSI. (shrink)

Quantum mechanics, which describes the behavior of subatomic particles, seems to challenge common sense. Waves behave like particles; particles behave like waves. You can tell where a particle is, but not how fast it is moving--or vice versa. An electron faced with two tiny holes will travel through both at the same time, rather than one or the other. And then there is the enigma of creation ex nihilo, in which small particles appear with their so-called antiparticles, only to (...) disappear the next instant in a tiny puff of energy. Since its inception, physicists and philosophers have struggled to work out the meaning of quantum mechanics. Some, like Niels Bohr, have responded to quantum mechanics' mysteries by replacing notions of position and velocity with probabilities. Others, like Einstein and Penrose, have disagreed and think that the entire puzzle reflects not a fundamental principle of nature but our own ignorance of basic scientific processes. Sneaking a Look at God's Cards offers the general reader a deep and real understanding of the problems inherent to the interpretation of quantum mechanics, from its inception to the present. The book presents a balanced overview of current debates and explores how the theory of quantum mechanics plays itself out in the real world. Written from the perspective of a leading European physicist, the book looks extensively at ideas from both sides of the Atlantic and also considers what philosophers have contributed to the scientific discussion of this field. Sneaking a Look at God's Cards sets out what we know about the endlessly fascinating quantum world, how we came to this understanding, where we disagree, and where we are heading in our quest to comprehend the seemingly incomprehensible. (shrink)

1. Introduction : humanity's urge to understand -- 2. Elements of scientific thinking : skepticism, careful reasoning, and exhaustive evaluation are all vital. Science Is universal -- Maintaining a critical attitude. Reasonable skepticism -- Respect for the truth -- Reasoning. Deduction -- Induction -- Paradigm shifts -- Evaluating scientific hypotheses. Ockham's razor -- Quantitative evaluation -- Verification by others -- Statistics : correlation and causation -- Statistics : the indeterminacy of the small -- Careful definition -- Science at the (...) frontier. When good theories become ugly -- Stuff that just does not fit -- 3. Christopher Columbus and the discovery of the "Indies" : it can be disastrous to stubbornly refuse to recognize that you have falsified your own hypothesis -- 4. Antoine Lavoisier and Joseph Priestley both test the befuddling phlogiston theory : junking a confusing hypothesis may be necessary to clear the way for new and productive science -- 5. Michael Faraday discovers electromagnetic induction but fails to unify electromagnetism and gravitation : it is usually productive to simplify and consolidate your hypotheses -- 6. Wilhelm Röntgen intended to study cathode rays but ended up discovering X-rays : listen carefully when Mother Nature whispers in your ear : she may be leading you to a Nobel Prize -- 7. Max Planck, the first superhero of quantum theory, saves the universe from the ultraviolet catastrophe : assemble two flawed hypotheses about a key phenomenon into a model that fits experiment exactly and people will listen to you even if you must revolutionize physics -- 8. Albert Einstein attacks the problem "Are atoms real?" from every angle : solving a centuries-old riddle in seven different ways can finally resolve it -- 9. Niels Bohr models the hydrogen atom as a quantized system with compelling exactness, but his later career proves that collaboration and developing new talent can become more significant than the groundbreaking research of any individual -- 10. Conclusions, status of science, and lessons for our time. Conclusions from our biographies -- What thought processes lead to innovation? -- Is the scientist an outsider? -- The status of the modern scientific enterprise -- Lessons for our time -- Can the scientific method be applied to public policy? -- Why so little interest in science? -- Knowledge is never complete. (shrink)

We apply the distinction between parameter independence and outcome independence to the linear and nonlinear models of a recent nonrelativistic theory of continuous state vector reduction. We show that in the nonlinear model there is a set of realizations of the stochastic process that drives the state vector reduction for which parameter independence is violated for parallel spin components in the EPR-Bohm setup. Such a set has an appreciable probability of occurrence (≈ 1/2). On the other hand, the linear model (...) exhibits only extremely small parameter dependence effects. We investigate some specific features of the models and we recall that, as has been pointed out recently, if one wants to be able to speak of definite outcomes (or equivalently of possessed objective elements of reality) at finite times, one has to slightly change the criteria for their attribution to physical systems. The concluding section is devoted to a detailed discussion of the difficulties which one meets when one tries to take, as a starting point for the formulation of a relativistic theory, a nonrelativistic scheme which exhibits parameter dependence. Here we derive a theorem which identifies the precise sense in which the occurrence of parameter dependence forbids a genuinely relativistic generalization. Finally we show how the appreciable parameter dependence of the nonlinear model gives rise to problems with relativity, while the extremely weak parameter dependence of the linear model does not give rise to any difficulty, provided one takes into account the appropriate criteria for the attribution of definite outcomes. (shrink)

The functioning of a subject in a changing environment is most effective from the point of view of survival if the subject can form, maintain and use internal representations of the external world for decision-making. These representations are also called reflection in a broad sense. Using it, one can win in reflexive games since an internal representation of the enemy allows predicting their future moves. The goal is to assess the reflexive potential of heuristic model objects – artificial neural networks (...) – in the reflexive games “Even-Odd” (or “Matching pennies”) and “Rock-Paper-Scissors”. We used homogeneous fully connected neural networks of small sizes (from 8 to 45 neurons). Games were played between neural networks with different configurations and parameters (size, step size for modifying weight coefficients). A set of reflexivity criteria is presented, corresponding to different levels of consideration: neuronal, behavioral, formal. The transitivity of formal success in the game is shown. The most successful configurations, however, may not meet other criteria of reflexivity. We hypothesize that the best compliance with the criteria and, as a consequence, universal success in reflection tasks is achievable for heterogeneous configurations with a structure in which the formation of hierarchical systems of attractors is possible. (shrink)

Obstetricians face difficult decisions when the interests of fetus and mother conflict. An example is the problem of choosing the delivery method when labour begins prematurely and the fetus is breech. Vaginal delivery involves risks for the breech fetus of brain damage or death caused by umbilical cord compression and head entrapment. Caesarean section might avoid these dangers but involves risks for the mother, including infection, haemorrhage and even death in a small percentage of cases. If a caesarean section (...) is performed the infant might die anyway, due to complications of prematurity. Thus, decisions about delivery method involve balancing the risks to mother and fetus. Uncertainty about the frequency of fetal injuries in vaginal breech deliveries adds to the difficulty of these decisions. (shrink)

Farmers in developed countries have established various tillage practices for crop production. These include plowing, disking, subsoiling, harrowing, field cultivating, rotary hoeing, and row-crop cultivating. But these conventional tillage practices necessitate the use of heavy equipment that often causes soil compaction, impairs soil physical conditions, and creates conditions leading to soil erosion. Many Western countries, studying their conventional tillage systems through the new perspective of sustainable approaches to agriculture, are developing new tillage practices, called conservation tillage, which limit tillage to (...) essential operations and prevent damage to soil. The majority of the small-scale farmers in developing countries use indigenous tillage systems. These are low-cost, locally adapted technologies that reflect considerable knowledge of sustainable agriculture. Ironically, the new conservation tillage systems currently being developed in the West have many characteristics of indigenous tillage systems. This paper compares conventional, conservation, and indigenous tillage practices, using examples from the United States and India, and concludes that, for sustainable food production, indigenous tillage practices in developing countries should continue to be used. (shrink)

The authors deal with the classic paradox of ethical theories, “Hume’s guillotine,” based on the contradiction in morality between what is and what should be. At the same time, the theological justification of moral principles is beyond this criticism, because the sacred commandments “by definition” combine what is and what should be, overcoming the “secular” gap between being and duty, and thus “the problem of transition from description to evaluation is removed.” Modern ways of removing this contradiction, revealed by Hume, (...) are considered from several points of view. Special attention is paid to the analogy between the development of ethical and mathematical theories, a synergistic approach to the formation of ethics, as well as to the ethical choice associated with the development of digital reality, which humanity will face soon. A synergistic approach can be viewed as a bridge “over the abyss of two cultures - natural science and humanities.” Now it has become clear that there can be many logics, geometries, versions of analysis of infinitely small, etc. Ethics can also be constructed and then put into practice. A classic example is the ethical code of King Lycurgus. Separate ethical systems are not able to ensure the survival of humanity under extreme conditions. Existence of general ethical rules in global crises allows many to survive. Without them, everyone would die. True amazement is the fact that the eight Dyakonov phase transitions in human history completely coincide with the crises periodicity presented in the text of the Apocalypse, where crises are figuratively called “beasts.” Then a vivid picture is given, a picture of the civilization transformation into a post-singular state, which goes beyond the horizon of scientific forecast. (shrink)

The economic importance of optimizing the environmental situation from the perspective of an entrepreneur are assessed in the article. The classification of administrative decisions taken in the course of the business activities is proposed. The authors identified a group of solutions directly providing optimization of environment external to the enterprise, solutions that have an indirect positive impact on the environment and solutions that improve ecology of industrial premises. The nature of economic effect of resulting solutions of various types is taken (...) into account. Vectors of influence of working conditions on the economic results of business activities are described. The nature and strength of the impact of model management decisions results of business activities are defined. Key performance indicators of entrepreneurial activity are identified: employee productivity, the amount of revenue and profitability, solvency, staff stability, the competitiveness of enterprises. Grouping the costs of ecological parameters optimization of the production environment is proposed. Relationship between level of working conditions and socio-psychological climate in the collective enterprise is disclosed. The methods of motivation of entrepreneurs in solving of environmental, production problems are considered. The role of training entrepreneurs engaged of medium and small businesses are underlined especially. Thus, in the article the relationship between environmental and economic problems of entrepreneurial activity is investigated. Role and opportunities of entrepreneurs in solving these problems are defined and structured. (shrink)

CtBP family proteins predominantly function as transcriptional corepressors. Studies with mutant mouse suggest that the two mouse genes, Ctbp1 and Ctbp2, play unique and redundant gene regulatory roles during development.1 Ctbp1-deficient mice are viable, but are small and die early, while Ctbp2 deficiency leads to embryonic lethality. Ctbp2-null mutation causes defects in axial patterning, heart morphogenesis and neural development. The Ctbp2 mutant phenotype is more severe in the absence of Ctbp1. The studies with Ctbp2 mutant embryos suggest that CtBP (...) can also activate transcription. A plant CtBP homolog, Angustifolia (AN), has recently been identified.2, 3 AN controls polar elongation of leaf cells via the microtubule cytoskeleton. Microarray analysis suggests that AN also functions as a transcriptional repressor. Thus, the CtBP family proteins control cellular processes by serving as transcriptional activators and regulators of the cytoskeleton as well as transcriptional corepressors. BioEssays 25:9–12, 2003. © 2002 Wiley Periodicals, Inc. (shrink)

Ran is one of the most abundant and best conserved of the small GTP binding and hydrolyzing proteins of eukaryotes. It is located predominantly in cell nuclei. Ran is a member of the Ras family of GTPases, which includes the Ras and Ras‐like proteins that regulate cell growth and division, the Rho and Rac proteins that regulate cytoskeletal organization and the Rab proteins that regulate vesicular sorting. Ran differs most obviously from other members of the Ras family in both (...) its nuclear localization, and its lack of sites required for post‐translational lipid modification. Ran is, however, similar to other Ras family members in requiring a specific guanine nucleotide exchange factor (GEF) and a specific GTPase activating protein (GAP) as stimulators of overall GTPase activity. In this review, the multiple cellular functions of Ran are evaluated with respect to its known biochemistry and molecular interactions. (shrink)

Modern thinkers long have been troubled by everyday talk. For example, one nineteenth-century Tory critic observes, “General small-talk” is any exchange “in mixed society, where men and women, young and old, wise and foolish, are all mingled together.” However available the occasion or obvious the topics, chatting is easy for the talented but awkward for the ungifted. On the other hand, “special, or professional small talk” is an exchange of words between persons of “the same mode of life, (...) as between two apothecaries, two dissenters, two lawyers, two beggars, two reviewers, two butlers, two statements, two thieves, &c.&c.&c.; in short all conversations which are tinctured with the art, craft, mystery, occupation... (shrink)

This is an introduction to world affairs in 1961 and after. It shows in bold outline how our rather small, increasingly overpopulated world has come to be dominated by the two giants powers, the USA and the USSR, with a new class of neutralist ex-colonial countries holding an increasingly important position. While Mr Pearson shows the part played by European or Western influence in creating one world, he also stresses that the outlying parts of the world are now independent (...) and dynamic, and that they have their own personality, aspirations and interests. Mr Pearson begins with the 'European springboard', showing how the Europe of the sixteenth century and after was a kind of powerhouse sending out currents of intellectual and political activity all over the world. Then he goes straight to the USA and the USSR and outlines their development. Next he turns to the time of European dominance and imperialism up to 1914; then to the course and effects of the two world wars; then to the decisive rise of the Asian contenders for great-power status and the decline of colonialism. Final chapters outline the history of the Middle East and comment on the 'lands of the future', especially Africa. (shrink)

We present a proof system for a multimode and multimodal logic, which is based on our previous work on modal Martin-Löf type theory. The specification of modes, modalities, and implications between them is given as a mode theory, i.e., a small 2-category. The logic is extended to a lambda calculus, establishing a Curry–Howard correspondence.

SummaryHeterozygous 4.1 hereditary elliptocytosis results from the absence of one haploid set of protein 4.1, a major component of the red cell skeleton. Two successive epidemiological investigations revealed fifteen probands in the French Northern Alps. The frequency of this disease seems to be very high in four small villages isolated in the Aravis mountains. The genealogical study shows that eleven probands share common ancestors who lived eight or ten generations ago in these villages. Thus there was probably a founder (...) effect from one pair of ancestors, strengthened by endogamy. In contrast, four probands originate from another area and are not genealogically related. Recent results in molecular genetics support the present data. (shrink)

In dealing with the whole complex of questions concerning human nature, no small role is played by the problem of language — the role of language in man's life — both personal and social. In successive periods of human history different representatives of social thought saw in different perspectives the role of language in human life and its influence on social development.

A very slight reading of Clement of Alexandria is enough to prove how deeply he is indebted to Plato both in respect of language and of thought. Quotations from Plato are to be found throughout Clement's works, and in many cases acknowledgment is made of their origin. In addition there are frequent allusions, which for the most part the student of Plato can easily recognize. Clement invariably shows a profound respect for the Greek philosopher, whom he looks upon as a (...) seeker after truth and as an authority, we may almost say, second only to the Scriptures. A careful comparison of the Protrepticus with the Phaedrus, results of which are given below, will furnish a striking illustration of the close dependence of Clement upon Plato. The Protrepticus is a short work, occupying in space not more than one–twelfth of Clement's extant writings, while the Phaedrus is even smaller in proportion to the whole of Plato. It is remarkable that so much inter-connexion should be found in so small a field, especially when we remember that the references to the Phaedrus represent by no means the whole of Clement's drawing upon Plato in the Protrepticus. There are allusions also to the Theaetetus, Republic, Charmides, Laws and Epistles, and possibly to the Politicus, Cratylus, Philebus, Symposium and Apology. (shrink)

INTRODUCTION: Delusional misidentification syndromes (DMS) are a group of psychopathological experiences occurring in psychosis, involving the misidentification of a person or place. DMS are often accompanied by hostility towards the object of delusional misidentification. This is of a particular concern in perinatal mental illness due to the potential disruption of the mother-infant bond, and risk of neglect, violence, or infanticide towards a misidentified child. This review aimed to collate all published cases of DMS in postpartum psychosis to further understand how (...) these syndromes present in perinatal mental illness. METHODS: In August 2021, an online database search was conducted using PubMed, MEDLINE, PsycINFO, CINAHL, and Embase to identify all publications reporting DMS in the perinatal period. RESULTS: Nine papers were included in the review involving 8 case reports of Capgras syndrome and one case series involving 4 cases of Fregoli syndrome. Three cases identified organic pathology, which may have contributed to the presentation. The most common subject of misidentification was the patient’s husband (n = 7), followed by their baby (n = 6), hospital staff (n = 4), other family members (n = 3), and self (n = 1). Five cases remark on the impact of perinatal illness on the maternal-infant bond, of which four result in the mother being unwilling to care for the infant as the result of their delusional beliefs. CONCLUSION: This is the first systematic review of the literature in this field. Although small in number, these cases reveal several important learning points including that DMS can occur with or without underlying organic disease. Active exploration of the nature of delusions in postpartum psychosis is required to mitigate the risk of harm to the infant and mother-infant bond. It may also uncover that these syndromes are more common in postpartum psychosis than previously realized. (shrink)

In this third paper in a series on stochastic electrodynamics (SED), the nonrelativistic dipole approximation harmonic oscillator-zero-point field system is subjected to an arbitrary classical electromagnetic radiation field. The ensemble-averaged phase-space distribution and the two independent ensemble-averaged Liouville or Fokker-Planck equations that it satisfies are derived in closed form without furtner approximation. One of these Liouville equations is shown to be exactly equivalent to the usual Schrödinger equation supplemented by small radiative corrections and an explicit radiation reaction (RR) vector (...) potential that is similar to the Crisp-Jaynes semiclassical theory (SCT) RR potential. The wave function in this SED Schrödinger equation is shown to have thea priori significance of position probability amplitude. The other Liouville equation has no counterpart in ordinary quantum mechanics, and is shown to restrict initial conditions such that (i) The Wigner-type phase-space distribution is always positive, (ii) in the absence of an applied field, the only allowed solution of both equations is the quantum ground state, and (iii) if a previously applied field is suddenly turned off, then spontaneous transitions occur, with no need for a triggering perturbation as in SCT, until the system is in the ground state. It is also shown that the oscillator energy is a fluctuating quantity that must take on a continuum of values, with average value equal to the quantum ground-state energy plus a contribution due to the applied classical field. (shrink)

According to one productive and influential approach to cognition, categorization, object recognition, and higher level cognitive processes operate on a set of fixed features, which are the output of lower level perceptual processes. In many situations, however, it is the higher level cognitive process being executed that influences the lower level features that are created. Rather than viewing the repertoire of features as being fixed by low-level processes, we present a theory in which people create features to subserve the representation (...) and categorization of objects. Two types of category learning should be distinguished. Fixed space category learning occurs when new categorizations are representable with the available feature set. Flexible space category learning occurs when new categorizations cannot be represented with the features available. Whether fixed or flexible, learning depends on the featural contrasts and similarities between the new category to be represented and the individual's existing concepts. Fixed feature approaches face one of two problems with tasks that call for new features: If the fixed features are fairly high level and directly useful for categorization, then they will not be flexible enough to represent all objects that might be relevant for a new task. If the fixed features are small, subsymbolic fragments (such as pixels), then regularities at the level of the functional features required to accomplish categorizations will not be captured by these primitives. We present evidence of flexible perceptual changes arising from category learning and theoretical arguments for the importance of this flexibility. We describe conditions that promote feature creation and argue against interpreting them in terms of fixed features. Finally, we discuss the implications of functional features for object categorization, conceptual development, chunking, constructive induction, and formal models of dimensionality reduction. Key Words: concept learning; conceptual development; features; perceptual learning; stimulus encoding. (shrink)

Synthetic genomics is a new field of research in which small DNA pieces are assembled in a series of steps into whole genomes. The highly reduced genomes of host‐associated bacteria are now being used as models for de novo synthesis of small genomes in the laboratory. Bacteria with the smallest genomes identified in nature provide nutrients to their hosts, such as amino acids, co‐factors and vitamins. Comparative genomics of these bacteria enables predictions to be made about the gene (...) sets required for core cellular functions and the associated metabolic network for the biosynthesis of host‐selected compounds. Synthetic biology may ultimately enable researchers to make customized cell‐specific organelles for the production and delivery of drugs to humans and domestic animals. Synthetic genomics may also become the method of choice for functional analyses of genes and genomes from bacteria that cannot be cultivated in the laboratory. (shrink)

The authors explore how urban versus rural community location shapes the extent to which various individual, relational, and structural factors affect the gender gap in small business success. Building on previous research on gender and small business success, gender queuing theories, and gendered organization/institution theories, they develop a place-specific theory of the gender gap in small business success. The findings, based on small business data collected in urban and rural Iowa, support queuing arguments and raise questions (...) about the effectiveness of crowded-sector explanations. They indicate that the gender gap in small business success operates such that men-owned businesses are more successful in both urban and rural settings but that men-owned businesses are even more successful than women-owned businesses in urban than rural communities. The authors discuss the causes and consequences of the gender gap in small business success in rural and urban places and identify key issues for further research. (shrink)