To prepare for potential human infection challenge studies involving SARS-CoV-2, we convened a multidisciplinary working group to address ethical questions regarding whether and how much SAR...

Over the course of the 20th century, unprecedented growth in scientific discovery was fueled by broad growth in the number of university-based scientists. During this period the American undergraduate enrollment rate and number of universities with STEM graduate programs each doubled three times and the annual volume of new PhDs doubled six times. This generated the research capacity that allowed the United States to surpass early European-dominated science production and lead for the rest of the century. Here, we focus on (...) origins in the organizational environment and institutional dynamics instead of conventional economic factors. We argue that three trends of such dynamics in the development of American higher education not often considered together—mass undergraduate education, decentralized founding of universities, and flexible mission charters for PhD training—form a process characterized by a term coined here: access symbiosis. Then using a 90-year data series on STEM PhD production and institutional development, we demonstrate the historical progression of these mutually beneficial trends. This access symbiosis in the U.S., and perhaps versions of it in other nations, is likely one critical component of the integration of higher education development with the growing global capacity for scientific discovery. These results are discussed in terms of the contributions of American universities to the Century of Science, recent international trends, and its future viability. (shrink)

The peer commentaries on our Target Article, “Promoting Ethical Payment in Human Infection Challenge Studies,” offer a number of insights that will help advance the co...

People with lived experience are individuals who have first-hand experience of the medical condition being considered. The value of including the viewpoints of people with lived experience in health policy, health care, and health care and systems research has been recognized at many levels, including by funding agencies. However, there is little guidance or established best practices on how to include non-academic reviewers in the grant review process. Here we describe our approach to the inclusion of people with lived experience (...) in every stage of the grant review process. After a budget was created for a specific call, a steering committee was created. This group included researchers, people with lived experience, and health systems administrators. This group developed and issued the call. After receiving proposals, stage one was scientific review by researchers. Grants were ranked by this score and a short list then reviewed by people with lived experience as stage two. Finally, for stage three, the Steering Committee convened and achieved consensus based on information drawn from stages one and two. Our approach to engage people with lived experience in the grant review process was positively reviewed by everyone involved, as it allowed for patient perspectives to be truly integrated. However, it does lengthen the review process. The proposed model offers further practical insight into including people with lived experience in the review process. (shrink)

People with lived experience are individuals who have first-hand experience of the medical condition being considered. The value of including the viewpoints of people with lived experience in health policy, health care, and health care and systems research has been recognized at many levels, including by funding agencies. However, there is little guidance or established best practices on how to include non-academic reviewers in the grant review process. Here we describe our approach to the inclusion of people with lived experience (...) in every stage of the grant review process. After a budget was created for a specific call, a steering committee was created. This group included researchers, people with lived experience, and health systems administrators. This group developed and issued the call. After receiving proposals, stage one was scientific review by researchers. Grants were ranked by this score and a short list then reviewed by people with lived experience as stage two. Finally, for stage three, the Steering Committee convened and achieved consensus based on information drawn from stages one and two. Our approach to engage people with lived experience in the grant review process was positively reviewed by everyone involved, as it allowed for patient perspectives to be truly integrated. However, it does lengthen the review process. The proposed model offers further practical insight into including people with lived experience in the review process. (shrink)

Our aim in this paper is to evaluate Frank Jackson and Philip Pettit’s ‘program explanation’ framework as an account of the autonomy of the special sciences. We argue that this framework can only explain the autonomy of a limited range of special science explanations. The reason for this limitation is that the framework overlooks a distinction between two kinds of properties, which we refer to as ‘higher-level’ and ‘higher-order’ properties. The program explanation framework can account for the autonomy of (...) special science explanations that appeal to higher-level properties but it does not account for the autonomy of most of those explanations that appeal to higher-order properties. (shrink)

In this volume, fourteen scholars, many of them contemporaries of Professor Frank, engage with his legacy with important and seminal works which take some of ...

Frank Jackson champions the cause of conceptual analysis as central to philosophical inquiry. In recent years conceptual analysis has been undervalued and widely misunderstood, suggests Jackson. He argues that such analysis is mistakenly clouded in mystery, preventing a whole range of important questions from being productively addressed. He anchors his argument in discussions of specific philosophical issues, starting with the metaphysical doctrine of physicalism and moving on, via free will, meaning, personal identity, motion, and change, to ethics and the (...) philosophy of color. In this way the book not only offers a methodological program for philosophy, but also casts new light on some much-debated problems and their interrelations. (shrink)

Wind, water, and molten rock constantly tear apart and resculpt the natural world we live in, and people have always struggled to create structures that will permanently establish their existence on the land. Frank Golhke has committed his camera lens to documenting that fraught relationship between people and place, and this retrospective collection of his work by John Rohrbach reveals how people carve out their living spaces in the face of constant natural disruption. An acclaimed master of landscape photography, (...) Golhke explores in _Accommodating Nature_ how people configure the places where they live, work, and commune, both on an everyday level and in the aftermath of catastrophic destruction. Whether a ranch house anchored fast on an endless Texas plain, the shattered buildings and whipped trees left by a category 5 tornado, or the jagged cliffs of ash and rock created by the volcanic eruption of Mount St. Helens, the photographs unearth the ways in which new homes and lives emerge from the fragments of the old. Thought-provoking essays by Rebecca Solnit, Frank Gohlke, and John Rohrbach expand upon the issues raised by the images, contemplating the complexities of human and cultural geography and the relationships we have with our respective place. An arresting and vibrant visual essay combining magnificent vistas with intimate emotional detail, _Accommodating Nature_ exposes the intricate threads that bind our lives to the land surrounding us. (shrink)

This book offers a philosophical account of memory. Memory is remarkably interesting from a philosophical point of view. Our memories interact with mental states of other types in a characteristic way. They also have some associated feelings that other mental states lack. Our memories are special in terms of their representational capacity too, since we can have memories of objective events, and we can have memories of our own past experiences. Finally, our memories are epistemically special, in that beliefs formed (...) on the basis of our memories are protected from certain errors of misidentification and justified in a way which does not rely on any cognitive capacity other than memory. The aim of the book is to explain these features of memory. It proposes that memories have a particular functional role which involves past perceptual experiences and beliefs about the past and suggests that memories have a particular content as well; they represent themselves as having a certain causal origin. The book then accounts for the feelings associated with our memories as the experience of some of the things that our memories represent; things such as our own past experiences, or the fact the memories originate in those experiences. It also accounts for the special justification for belief afforded by our memories in terms of the content that memories have. The resulting picture is a unified account of several philosophically interesting aspects of memory. (shrink)

Many of the things that we try to explain, in both our common sense and our scientific engagement with the world, are capable of being explained more or less finely: that is, with greater or lesser attention to the detail of the producing mechanism. A natural assumption, pervasive if not always explicit, is that other things being equal, the more finegrained an explanation, the better. Thus, Jon Elster, who also thinks there are instrumental reasons for wanting a more fine-grained explanation, (...) assumes that in any case the mere fact of getting nearer the detail of production makes such an explanation intrinsically superior: “a more detailed explanation is also an end in itself”. Michael Taylor agrees: “A good explanation should be, amongst other things, as fine-grained as possible.”. (shrink)

How do we know our current states of mind--what we want, and believe in? Jordi Fernández proposes a new theory of self-knowledge, challenging the traditional view that it is a matter of introspection. He argues that we know what we believe and desire by 'looking outward', towards the states of affairs which those beliefs and desires are about.

_"A stimulating history of how the imagination interacted with its sibling psychological faculties—emotion, perception and reason—to shape the history of human mental life."—_The __Wall Street Journal__ To imagine—to see what is not there—is the startling ability that has fueled human development and innovation through the centuries. As a species we stand alone in our remarkable capacity to refashion the world after the picture in our minds. Traversing the realms of science, politics, religion, culture, philosophy, and history, Felipe Fernández-Armesto reveals the (...) thrilling and disquieting tales of our imaginative leaps—from the first _Homo sapiens_ to the present day. Through groundbreaking insights in cognitive science, Fernández-Armesto explores how and why we have ideas in the first place, providing a tantalizing glimpse into who we are and what we might yet accomplish. Unearthing historical evidence, he begins by reconstructing the thoughts of our Paleolithic ancestors to reveal the subtlety and profundity of the thinking of early humans. A masterful paean to the human imagination from a wonderfully elegant thinker, _Out of Our Minds_ shows that bad ideas are often more influential than good ones; that the oldest recoverable thoughts include some of the best; that ideas of Western origin often issued from exchanges with the wider world; and that the pace of innovative thinking is under threat. (shrink)

What is the nature of, and what is the relationship between, external objects and our visual perceptual experience of them? In this book, Frank Jackson defends the answers provided by the traditional Representative theory of perception. He argues, among other things that we are never immediately aware of external objects, that they are the causes of our perceptual experiences and that they have only the primary qualities. In the course of the argument, sense data and the distinction between mediate (...) and immediate perception receive detailed defences and the author criticises attempts to reduce perceiving the believing and to show that the Representative theory makes the external world unknowable. Jackson recognises that his views are unfashionable but argues in detail that they are to be preferred to their currently favoured competitors. It will become an obvious point of reference for all future work on the philosophy of perception. (shrink)

Frank Ramsey was the greatest of the remarkable generation of Cambridge philosophers and logicians which included G. E. Moore, Bertrand Russell, Ludwig Wittgenstein and Maynard Keynes. Before his tragically early death in 1930 at the age of twenty-six, he had done seminal work in mathematics and economics as well as in logic and philosophy. This volume, with a new and extensive introduction by D. H. Mellor, contains all Ramsey's previously published writings on philosophy and the foundations of mathematics. The (...) latter gives the definitive form and defence of the reduction of mathematics to logic undertaken in Russell and Whitehead's Principia Mathematica; the former includes the most profound and original studies of universals, truth, meaning, probability, knowledge, law and causation, all of which are still constantly referred to, and still essential reading for all serious students of these subjects. (shrink)

First published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.

Despite the renewed interest in Frank Lloyd Wright and the increasing body of literature that has illuminated his career, the deeper meaning of his architecture continues to be elusive. His own writings are often interesting commentaries but tend not to enlighten us as to his design methodology, and it is difficult to make the connection between his stated philosophy and his actual designs. This book is a refreshing account that evaluates Wright’s contribution on the basis of his architectural form, (...) its animating principle and consequent meaning. Wright’s architecture, not his persona, is the primary focus of this investigation. This study presents a comprehensive overview of Wright’s work in a comparative analytical format. Wright’s major building types have been identified to enable the reader to pursue a more systematic understanding of his work. The conceptual and experiential order of each building group is demonstrated visually with specially developed analytical illustrations. These drawings offer vital insights into Wright’s exploration of form and underscore the connection between form and principle. The implications of Wright’s work for architecture in general serves as an important underlying theme throughout. This volume also integrates the research of several noted scholars to clarify the interaction of theory and practice in Wright’s work, as well as the role of formal order in architectural experience in general. By seeing how Wright integrates his intuitive and intellectual grasp of design, the reader will build a keen awareness of the rational and coherent basis of his architecture and its symbiotic relationship with emotional, qualitative reality. A graphic taxonomy of plans of Wright’s building designs helps the reader focus on specific subjects. Among the diverse areas covered are sources and influences of Wright’s work, domestic themes and variations, public buildings and skyscraper designs, and the influence of site on design. Complete with a chronology of the master architect’s work, Frank Lloyd Wright: Between Principle and Form is an important reference for students, architects and architectural historians. (shrink)

In this book, I make use of an idea from economics to suggest how noble human tendencies might not only have survived the ruthless pressures of the material world, but actually have been nurtured by them.

Los teóricos de la democracia dejaron de lado la pregunta de quién legalmente forma parte del "pueblo" autorizado, pregunta que atraviesa a todas las teoría de la democracia y continuamente vivifica la práctica democrática. Determinar quién constituye el pueblo es un dilema inabordable e incluso imposible de responder democráticamente; no es una pregunta que el pueblo mismo pueda decidir procedimentalmente porque la propia premisa subvierte las premisas de su resolución. Esta paradoja del mandato popular revela que el pueblo para ser (...) mejor comprendido como una demanda política, como un proceso de subjetivación, surge y se desarrolla en distintos contextos democráticos. En Estados Unidos el disputado poder para hablar en beneficio del pueblo deriva de un excedente constitutivo heredado de la era revolucionaria, a partir del hecho de que desde la Revolución el pueblo ha sido por vez primera encarnado por la representación y como exceso de cualquier forma de representación. La autoridad posrevolucionaria del vox populi deriva de esa continuamente reiterada pero nunca realizada referencia a la soberanía del pueblo a partir de la representación, legitimidad a partir de la ley, espíritu a partir de la letra, la palabra a través de la palabra. Este ensayo examina la emergencia histórica de este exceso de democracia en el período revolucionario, y cómo este habilita a una subsecuente historia de "momentos constituyentes", momentos cuando subautorizados -radicales, entidades autocreadas-, se apoderan del manto de la autoridad, cambiando las reglas de la autoridad en ese proceso. Estos pequeños dramas de reclamos de autoridad política para hablar en nombre del pueblo son felices, aun cuando explícitamente rompan con los procedimientos o reglas estatuidas para representar la voz popular. -/- Momentos constituyentes: paradojas y poder popular en los Estados Unidos de América posrevolucionarios [traducción], Revista Argentina de Ciencia Política, N°15, EUDEBA, Buenos Aires, Octubre 2012, pp. 49-74. ISSN: 0329-3092. Introducción de “Constituent Moments: Enacting the People in Postrevolutionary America”, de Jason Frank [Ed.: Duke University Press Books, enero de 2010. ISBN-10: 0822346753; ISBN-13: 978-0822346753]. (shrink)

In At the Will of the Body , Arthur Frank told the story of his own illnesses, heart attack and cancer. That book ended by describing the existence of a "remission society," whose members all live with some form of illness or disability. The Wounded Storyteller is their collective portrait. Ill people are more than victims of disease or patients of medicine they are wounded storytellers. People tell stories to make sense of their suffering when they turn their diseases (...) into stories, they find healing. Drawing on the work of authors such as Oliver Sacks, Anatole Broyard, Norman Cousins, and Audre Lorde, as well as from people he met during the years he spent among different illness groups, Frank recounts a stirring collection of illness stories, ranging from the well-known--Gilda Radner's battle with ovarian cancer--to the private testimonials of people with cancer, chronic fatigue syndrome, and disabilties. Their stories are more than accounts of personal suffering: they abound with moral choices and point to a social ethic. Frank identifies three basic narratives of illness in restitution, chaos, and quest. Restitution narratives anticipate getting well again and give prominence to the technology of cure. In chaos narratives, illness seems to stretch on forever, with no respite or redeeming insights. Quest narratives are about finding that insight as illness is transformed into a means for the ill person to become someone new. (shrink)

Prescriptive political and moral theories contain ideas about what human beings are like and about what, correspondingly, is good for them. Conceptions of human “nature” and corresponding human good enter into normative argument by way of support and justification. Of course, it is logically open for the ratiocinative traffic to run the other way. Strongly held convictions about the rightness or wrongness, goodness or badness, of certain social institutions or practices may help condition and shape one's responses to one or (...) another set of propositions about what people are like and what, in consequence, they have reason to value. (shrink)

Frank Ramsey was a brilliant Cambridge philosopher, mathematician, and economist who died in 1930 at 26 having made landmark contributions to decision theory, game theory, mathematics, logic, semantics, philosophy of science, and the theory of truth. This rich biography tells the story of his extraordinary life and intellectual achievement.

At the most general level I am interested in how we come to make sense of the world around us. Much of this research involves asking how intuitive explanations and understandings emerge in development and how they are related to notions of cause, mechanism and agency. These relations are linked to broader questions of what concepts are, how they change with development and increasing expertise and how they are structured in adults.

I'm pleased to have been offered the chance of replying to Joseph Frank's criticisms . He is a courteous opponent, though capable of a certain asperity. . . . Frank complains that his critics appear incapable of attending to what he really said in his original essay. It is the blight critics are born for; and it is undoubtedly sometimes caused by the venal haste of reviewers, and sometimes by native dullness, and sometimes by malice. But there are (...) other reasons why an author may sometimes feel himself to be misrepresented. One is that a genuinely patient and intelligent reader may be more interested in what the piece under consideration does not quite say than in what is expressly stated. Another is the consequence of fame. Frank's original article is over thirty years old; it crystallised what had been for the most part vague notions, ideas that were in the air, and gave them a memorable name. "Spatial form" entered the jargon of the graduate school and began an almost independent existence. The term might well be used by people who had never read the essay at all; or they might casually attribute to him loose inferences made by others from the general proposition—inferences he had already disallowed and now once more contests. It must be difficult, particularly for an exasperated author, to distinguish between these causes of apparent misrepresentation. But sometimes it can be done; and then it will appear that the effect of the first is far more interesting than that of the second cause. For the suggestion then must be that the author has repressed a desire to take a position which, in his manifest argument, he differentiates from his own. This, as it happens, is what he advances as an explanation of certain ambiguities in my Sense of an Ending; the least one can say is that it is perfectly possible. Frank Kermode is the author of The Sense of an Ending: Studies in the Theory of Fiction, Continuities, and Shakespeare, Spenser, Donne: Renaissance Essays; his works also include The Classic and The Genesis of Secrecy. His contributions to Critical Inquiry are "Novels: Recognition and Deception" , "A Reply to Denis Donoghue" , and "Secrets and Narrative Sequence". (shrink)

This collection introduces the reader to some of the most interesting current work on conditionals. Particular attention is paid to possible world semantics for conditionals, the role of conditional probability in helping us to understand conditionals, implicature and the material conditional, and subjunctive versus indicative conditionals. Contributors include V.H. Dudman, Dorothy Edgington, Nelson Goodman, H.P. Grice, David Lewis, and Robert Stalnaker.

Values-based practice (VBP), developed as a partner theory to evidence-based medicine (EBM), takes into explicit consideration patients’ and clinicians’ values, preferences, concerns and expectations during the clinical encounter in order to make decisions about proper interventions. VBP takes seriously the importance of life narratives, as well as how such narratives fundamentally shape patients’ and clinicians’ values. It also helps to explain difficulties in the clinical encounter as conflicts of values. While we believe that VBP adds an important dimension to the (...) clinician’s reasoning and decision-making procedures, we argue that it ignores the degree to which values can shift and change, especially in the case of psychiatric disorders. VBP does this in three respects. First, it does not appropriately engage with the fact that a person’s values can change dramatically in light of major life events. Second, it does not acknowledge certain changes in the way people value, or in their modes of valuing, that occur in cases of severe psychiatric disorder. And third, it does not acknowledge the fact that certain disorders can even alter the degree to which one is capable of valuing anything at all. We believe that ignoring such changes limits the degree to which VBP can be effectively applied to clinical treatment and care. We conclude by considering a number of possible remedies to this issue, including the use of proxies and written statements of value generated through interviews and discussions between patient and clinician. (shrink)

Frank Palmeri sees the conjectural histories of Rousseau, Hume, Herder, and other Enlightenment philosophers as a template for the development of the social sciences in the nineteenth and early twentieth centuries. Without documents or memorials, these thinkers, he argues, employed conjecture to formulate a naturalistic account of society's commercial and secular progression. This approach can be traced in the work of political economists, anthropologists, sociologists, and sociologists of religion, and its speculative framework creates a surprising ambivalence toward modernity in (...) these disciplines. In addition, Palmeri shows that conjectural histories by Darwin and Nietzsche opened the way to new disciplines in the late twentieth century. (shrink)

Aristotle famously distinguishes between merely doing a virtuous action and acting in the way in which a virtuous person would. Against an interpretation prominent in recent scholarship, I argue that ‘acting virtuously,’ in the sense of exercising a virtue actually possessed, is prior to ‘virtuous action,’ understood generically. I propose that the latter notion is best understood as a derivative abstraction from the former, building upon a reading of a neglected distinction between per se and coincidentally just action in Nicomachean (...) Ethics 5, and thus shed light on the meaning and philosophical significance of the priority of acting from virtue. (shrink)

In this work, the first overview of the German Idealism that is both conceptual and methodological, Paul W. Franks offers a philosophical reconstruction that is...

The concept of the universe is used in physical cosmology differently from the usual meaning of the term, naively considered as the entire reality. Traditionally, thinking about the whole led to logical contradictions. Taking as reference the Kantian antecedent, different contemporary philosophical notions of the universe are analysed in the first part of this paper, including realist and constructivist approaches, as well as a notion of the universe as a physical object. In the second part, the specific notion from the (...) standard physical cosmology is discussed. Although modelling the universe as a physical system provides a specific way to define some global properties, the universe as a whole remains empirically inaccessible. Hence, the discussion about the under-determined global properties depends ultimately on philosophical preferences. Under these circumstances, it is argued that the realist interpretation of such properties becomes problematic because it leads to unstable conclusions. Finally, it is argued that the notion of the universe as conceived in standard cosmology is not necessarily consistent with an approach that considers it to be a physical object. (shrink)