Background: Individuals with psychopathic traits demonstrate an attenuated emotional response to aversive stimuli. However, recent evidence suggests heterogeneity in emotional reactivity among individuals with psychopathic or callous-unemotional (CU) traits, the emotional detachment dimension of psychopathy. We hypothesize that primary variants of psychopathy will respond with blunted affect to negatively valenced stimuli, whereas individuals marked with histories of childhood trauma/maltreatment exposure, known as secondary variants, will display heightened emotional reactivity. To test this hypothesis, the present study examined fear-potentiated startle between psychopathy (...) variants while viewing aversive, pleasant, and neutral scenes. Method: 238 incarcerated adolescent (M age = 16.8, SD = 1.11 years) boys completed a picture-startle paradigm and self-report questionnaires assessing CU traits, antisocial-aggressive behavior, and maltreatment. Results: Latent profile analyses identified four classes; primary variants (high CU traits, high aggression, low maltreatment; n = 46), secondary variants (high CU traits, high aggression, high maltreatment; n = 42), and two nonpsychopathic groups differentiated on maltreatment experience (n = 148). Findings from an ANOVA comparing identified groups on startle amplitude difference scores (i.e., aversive-neutral) suggested a main effect for group, F(3,196)=8.91, p<.001, η2 = .12. Primary variants of juvenile psychopathy displayed reduced startle potentiation to aversive images (threat and victim scenes), whereas secondary variants distinguished by high levels of childhood maltreatment did not. Conclusions: Findings add to a rapidly growing body of literature supporting the possibility of multiple developmental pathways to psychopathy (i.e., equifinality), and extend it by finding support for divergent potential biomarkers between primary and secondary psychopathy variants. (shrink)

This chapter addresses concerns that pragmatic encroachers are committed to problematic knowledge variance. It first replies to Charity Anderson and John Hawthorne’s new putative problem cases, which purport to show that pragmatic encroachment is committed to problematic variations in knowledge depending on what choices are available to the potential knower. It argues that the new cases do not provide any new reasons to be concerned about the pragmatic encroacher’s commitment to knowledge-variance. The chapter further argues that concerns about knowledge-variance are (...) not limited to the pragmatic encroacher, but come up for traditional purist invariantism as well. (shrink)

Les absents jouent un rôle considérable dans la création des signes qui servent, dans toute société, à désigner, nommer, et même instituer les places des présents et celles des absents tout en mettant du sens dans leurs relations. La sémiotique conçoit ainsi le processus d'humanisation à travers la création des signes alors que la psychanalyse a permis, à sa manière, de voir combien le monde des absents participe à la construction psychique du sujet. La fonction de l'absence perceptive chez le (...) bébé est également étudiée dans cet ouvrage dans sa contribution à la transformation des signes gestuels binaires en signes ternaires qui intègrent du sens. Ces transformations sémiotiques sont aussi éclairées par le regard des poètes et des philosophes présents dans cet ouvrage. (shrink)

The identification of a reference standard is a major problem in diagnostic imaging. This comment invites reflection on the notion by illustrating three philosophical approaches to truth and evidence.

Recently, there has been increasing interest in methodological aspects of advanced imaging, including the role of guidelines, recommendations, and experts’ consensus, the practice of self-referral, and the risk of diagnostic procedure overuse. In a recent Delphi study of the European Association for Nuclear Medicine (EANM), panelists were asked to give their opinion on 47 scientific questions about imaging in prostate cancer. Nine additional questions exploring the experts’ attitudes and opinions relating to the procedure of consensus building itself were also included. (...) The purpose was to provide insights into the mechanism of recommendation choice and consensus building as seen from the experts’ point of view. Results: Regarding the factors likely to influence the willingness to refer a patient for imaging, the most voted were incorporation into guidelines and data from scientific literature, while personal experience and personal relationship were chosen by a small minority. Regarding the recommendations more relevant to prescribe an imaging procedure, it resulted the incorporation into guidelines promoted by scientific societies (59% of votes); these guidelines also resulted the more trusted. With respect to patients’ preferences considered when prescribing an imaging procedure, the most voted was accuracy, resulted more important than easy access and time to access to the procedure. The majority of the experts expressed the opinion that there is a scarce use of imaging procedures in prostate cancer. With respect to the most relevant factor to build consensus, it resulted the transparency of the process (52% of votes), followed by multidisciplinarity of contributors. The main obstacle to incorporation of modern imaging procedures into guidelines resulted the lack of primary literature on clinical impact. Conclusions: Firstly, the panelists portray themselves as having Evidence-Based Medicine oriented and scientifically inclined attitudes and preferences. Secondly, guidelines and recommendations from scientific societies, especially clinical ones, are positively taken into account as factors influencing decisions, but panelists tend to consider their own appraisal of the scientific literature as more relevant. Thirdly, in respect of overuse, panelists do not think that advanced diagnostic procedures are overutilized in the specific case of Prostate Cancer, but rather they are underutilized. (shrink)

The book in front of you is the first international academic volume on the legal, philosophical and economic aspects of the rise of 3D printing. In recent years 3D printing has become a hot topic. Some claim that it will revolutionize production and mass consumption, enabling consumers to print anything from clothing, automobile parts and guns to various foods, medication and spare parts for their home appliances. This may significantly reduce our environmental footprint, but also offers potential for innovation and (...) creativity. At the same time 3D printing raises social, ethical, regulatory and legal questions. If individuals can print anything they want, how does this affect existing systems of intellectual property rights? What are the societal consequences of the various types of products one can print with a 3D printer, for example weapons? Should all aspects of 3D printing be regulated, and if so, how and to what ends? How will businesses (have to) change their way of working and their revenue model in light of the shift to printing-on-demand? How will the role of product designers change in a world where everyone has the potential to design their own products? These and other questions are addressed in high quality and in-depth contributions by academics and experts, bringing together a wide variety of academic discussions on 3D printing from different disciplines as well as presenting new views, broadening the discussion beyond the merely technical dimension of 3D printing. Bibi van den Berg is Associate Professor at eLaw, the Center for Law and Digital Technologies at Leiden University, The Netherlands. Simone van der Hof is Full Professor at eLaw in Leiden and Eleni Kosta is Associate Professor at TILT, the Tilburg Institute for Law, Technology and Society at Tilburg University, The Netherlands. (shrink)

Psychologists and philosophers agree that personal narratives are a central component of one’s identity. The concept of narrative self has been proposed to capture this aspect of selfhood. In recent times, it has been a matter of debate how the narrative self relates to the embodied and experiential dimension of the self. In this debate, the role attributed to inner speech is that of constructing and maintaining personal narratives. Indeed, evidence suggests that inner speech episodes are involved in self-reflection and (...) autobiographical reasoning. That is, previous works have focused mostly, if not solely, on the role of inner speech for narrative self-understanding. However, inner speech is also involved in enacting personal narratives. In such cases, the content of the inner speech episodes is not in the service of the construction of narratives, rather it implies the identification with the character of the personal narratives. I introduce two instances of the use of inner speech for narrative self-enactment: positive self-talk and stereotype threat. I conclude by considering the implications of the examples introduced for the debate regarding the relation between the narrative and the embodied dimensions of selfhood. (shrink)

Though the ancient Greek philosophical concept of scholê is usually translated as 'leisure', there is a vast difference between the two. Leisure, derived from Latin licere, has its roots in Roman otium and connotes the uses of free time in ways permitted by the status quo. Scholê is the actualization of mind and one's humanity within a republic that devotes its culture to making such a choice possible. This volume traces the background in Greek culture and the writings of Plato (...) of a daring proposal presented by Aristotle, that scholê is a principle for political organization. The concept of scholê by and large did not survive Aristotle. To sharpen our understanding of scholê the book goes on to identify the concepts of leisure which we have inherited from the intellectuals of the Hellenistic and Roman empires and the early Church Fathers. Scholê also had its contrary ascholia – busyness – which Plato described as a social and psychological pathology and his analysis suggests why, due to these ills, current visions of a leisure society are highly unlikely. (shrink)

This concise, accessible and engaging collection debunks the myths and corrects the falsehoods surrounding one of the most famous scientific figures in history - Charles Darwin. Leading scholars examine his life and work to set the historical record straight, and to draw conclusions about the very nature of science itself.

Science appeared in modern Greece in the first decades after its establishment as a sovereign state in 1828. The University of Athens, the Royal Observatory, the Botanical Garden, and the Natural History Museum were quickly established as spaces of scientific activity. Greek scientists were enthusiastic participants in the emerging Greek public sphere, often not only as science experts, but also as poets, intellectuals and political personae. In a space whose cultural, intellectual and historical boundaries were still being negotiated, the choice (...) of language was not a given but a pressing, sensitive national desideratum. This article examines how Greek scientists used languages to communicate with their peers and with their publics, how they handled terminology and nomenclature, and how the issues surrounding the Greek language in particular affected their practice as scientists. The article aims to show that, in nineteenth-century Greece, languages were not passive, neutral vehicles of communication, but rather integral components of the practice of science. (shrink)

This paper presents an emerging aspect of intentionality through recent Artificial Intelligence (AI) developments in art and design. Our main thesis is that, if we focus just on the outcome of the artistic process, the intentionality of the artist does not have any relevance. Intention is measured as a result of actions regardless of whether they are human-based or not as long as there is an esthetical value intersubjectively acknowledged. In other words, what matters is the ‘intentio’ embedded in the (...) work of art (the output) rather than the ‘intendere’ (the process). By considering the former aspect, intentionality becomes free of human intervention, therefore 'unintentional'. This thesis is supported through a range of examples related to AI in general and AI art in particular. However, in the case of a self-driving vehicle, the macro-goal of the system is fixed by humans, even though the AI system itself will take care of decomposing the macro-goal into a set of micro-goals and take the corresponding decisions. In the case of art, the system does not need to have any exterior goal to the extent that art is pure freedom of expression, as many philosophers have acknowledged. In this sense, the decisions of any AI system generating art or design are independent of humans and must be judged only on the ground of the final outcome. A work of art will be judged ‘artistic’ to the extent that humans will recognize an artistic intent in the work itself. In particular, the introduction of random processes makes an AI-generated artwork fully independent of human creativity. (shrink)

I propose an analysis of deception as the activity of intentionally misleading other agents’ hypothetical inferences. Understanding deception in this way has the advantages of clarifying the epistemological and cognitive dynamics involved in deception. Indeed, if deception can be framed as the intentional manipulation of others’ hypothetical inferences so that they will accept the false or disadvantageous hypotheses, then a better understanding of the epistemological and cognitive dynamics involved in deception will emerge by clarifying how abduction works. Tracing it back (...) to Peirce’s analysis, I will focus on recent perspectives on abduction, which stress the inherent strategic character of abductive cognition and offer a realistic description of the reasoners’ capabilities and their scant resources, both internal (computational power) and external (time and information available). To support and substantiate my thesis, I will examine psychological analyses of military deception. I will conclude by remarking the advantages of the thesis here presented to better understand the epistemological dynamics of deception and by highlighting the questions it leaves open for further investigations. (shrink)

The widely known but also somewhat esoteric Mach principle envisages a fully relational formulation of physical theories without any reference to a concept of ‘absolute space’. When applied to classical mechanics, under the guise of an extended symmetry group, this procedure is known to lead to an equation of motion with inertial-like forces that are sourced by the mass distribution of the system itself. In this paper we follow a similar procedure and reformulate the Schrödinger equation of non-relativistic quantum mechanics (...) in a fully Machian way. Just like its classical counterpart, the resulting quantum theory is fully relational in the positions and momenta of the bodies comprising a given physical system, leaving no room for the notion of absolute space. (shrink)

How happy it is to recall Imre Lakatos. Now, fifteen years after his death, his intelligence, wit, generosity are vivid. In the Preface to the book of Essays in Memory of Imre Lakatos, the editors wrote:... Lakatos was a man in search of rationality in all of its forms. He thought he had found it in the historical development of scientific knowledge, yet he also saw rationality endangered everywhere. To honor Lakatos is to honor his sharp and aggressive criticism as (...) well as his humane warmth and his quick wit. He was a person to love and to struggle with. The book before us carries old and new friends of that Lakatosian spirit further into the issues which he wanted to investigate. That the new friends include a dozen scientific, historical and philosophical scholars from Greece would have pleased Lakatos very much, and with an essay from China, he would have smiled all the more. But the key lies in the quality of these papers, and in the imaginative organization of the conference at Thessaloniki in summer 1986 which worked so well. (shrink)

LetSbe the group of finitely supported permutations of a countably infinite set. Let$K[S]$be the group algebra ofSover a fieldKof characteristic 0. According to a theorem of Formanek and Lawrence,$K[S]$satisfies the ascending chain condition for two-sided ideals. We study the reverse mathematics of this theorem, proving its equivalence over$RC{A_0}$ to the statement that${\omega ^\omega }$is well ordered. Our equivalence proof proceeds via the statement that the Young diagrams form a well partial ordering.

Advanced medical imaging, such as CT, fMRI and PET, has undergone enormous progress in recent years, both in accuracy and utilization. Such techniques often bring with them an illusion of immediacy, the idea that the body and its diseases can be directly inspected. In this paper we target this illusion and address the issue of the reliability of advanced imaging tests as knowledge procedures, taking positron emission tomography in oncology as paradigmatic case study. After individuating a suitable notion of reliability, (...) we argue that PET is a highly theory-laden and non-immediate knowledge procedure, in spite of the photographic-like quality of the images it delivers; the diagnostic conclusions based on the interpretation of PET images are population-dependent; PET images require interpretation, which is inherently observer-dependent and therefore variable. We conclude with a three-step methodological proposal for enhancing the reliability of advanced medical imaging. (shrink)

What was science for the Orthodox Greek theologian of the nineteenth century? How did it feature in his (theologians were all men at the time) own work? This article is an attempt to describe the science and religion interactions by placing Greek Orthodox theologians of the nineteenth century in the center of the historical narrative, rather than treat them as occasional deuteragonists in the scientists’ historiography. The picture that emerges is far more complicated than one of antagonism, indifference, conflict, or (...) coexistence. Greek theologians saw themselves as scientists and treated theology as a positive, rational science. They developed strategies to delineate their disciplinary borders and safeguard their identity as expert scholars by harnessing their university and academic credentials. For that reason, they had to invoke famous German and other Western theologians, while ensuring that they were seen as true defenders of Orthodox Christianity. The idea of science was an integral part of this achievement. (shrink)

The romance Imberios and Margarona does not belong to the Renaissance. It does not acknowledge many of the issues which become current in the age of Humanism: the value of individual consciousness, to name but one, will wait until the seventeenth century to be explored in Greek literature. And yet, the vintage of Imberios is hybrid: being late medieval and modelled after a popular European prototype, it slants ever so gently towards what will later be fully fledged humanistic sensibilities.

The romance Imberios and Margarona does not belong to the Renaissance. It does not acknowledge many of the issues which become current in the age of Humanism: the value of individual consciousness, to name but one, will wait until the seventeenth century to be explored in Greek literature. And yet, the vintage of Imberios is hybrid: being late medieval and modelled after a popular European prototype, it slants ever so gently towards what will later be fully fledged humanistic sensibilities.

In Neither Physics Nor Chemistry, Kostas Gavroglu and Ana Simoes examine the evolution of quantum chemistry into an autonomous discipline, tracing its development from the publication of early papers in the 1920s to the dramatic changes ...

The article deals with the legal, political, philosophical and religious dimensions of Socrates’ trial and execution. It considers the issue in five separate aspects: 1) the validity of charging Socrates with impiety and corrupting the youth of the Athens; 2) the legal basis of the philosopher’s indictment; 3) the then manner of conducting a legal trial in the Athens; 4) the extent to which Socrates’ conviction can ultimately be characterized as unjust and — finally — 5) the cultural ramifications of (...) the philosopher’s trial and execution. (shrink)

This paper analyzes the ongoing university reform in Russia by underlining historical roots and peculiarities of its system of higher education. It is pointed out that the Soviet model of economy, political and ideological bias deeply impacted the university system and enforced its estrangement from foreign universities. A limited number of the best Soviet higher education institutions which provided a military-oriented education and fundamental research were re-casted along the so called “PhysTech” system after the end of the WWII. As a (...) result of this system, higher education and R&D in Russia is not presently competitive in the educational international market. Closing the gap between Russian universities and the “global university” approach and raising university competitiveness are the main objectives of the current reform in science and education. As universities are considered core actors of knowledge economy, a new set of federal and national research universities was created. However, reform faces numerous conceptual and institutional obstacles, risks and constraints are significant, and positive outcomes elusive. (shrink)

We present the design of a secure and privacy preserving e-petition system that we have implemented as a proof-of-concept demonstrator. We use the Belgian e-ID card as source of authentication, and then proceed to issue an anonymous credential that is used to sign petitions. Our system ensures that duplicate signatures are detectable, while preserving the anonymity of petition signers. We analyze the privacy and security requirements of our application, present an overview of its architecture, and discuss the applicability of data (...) protection legislation to our system. (shrink)