The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and incomplete. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct.

There is a growing interest in non-invasive stimulation interventions as treatment strategies to improve functional outcomes and recovery after spinal cord injury. Repetitive transcranial magnetic stimulation is a neuromodulatory intervention which has the potential to reinforce the residual spinal and supraspinal pathways and induce plasticity. Recent reviews have highlighted the therapeutic potential and the beneficial effects of rTMS on motor function, spasticity, and corticospinal excitability modulation in SCI individuals. For this scoping review, we focus on the stimulation parameters used in (...) 20 rTMS protocols. We extracted the rTMS parameters from 16 published rTMS studies involving SCI individuals and were able to infer preliminary associations between specific parameters and the effects observed. Future investigations will need to consider timing, intervention duration and dosage that may depend on the stage, the level, and the severity of the injury. There is a need for more real vs. sham rTMS studies, reporting similar designs with sufficient information for replication, to achieve a significant level of evidence regarding the use of rTMS in SCI. (shrink)

Using computer programs to correct English grammar can improve the efficiency of English grammar correction, improve the effect of error correction, and reduce the workload of manual error correction. In order to deal with and solve the problem of loss evaluation mismatch in the current mainstream machine translation, this study proposes the application of the deep learning method to propose an algorithm model with high error correction performance. Therefore, the framework of confrontation learning network is introduced to continuously improve the (...) optimization model parameters through the confrontation training of discriminator and generator. At the same time, convolutional neural network is introduced to improve the algorithm training effect, which can make the correction sentences generated by the model generator better in confrontation. In order to verify the performance of the algorithm model, P-value, R-value, F 0.5-value, and MRR-value were selected for the comprehensive evaluation of the model performance index. The simulation results of the CoNLL-2014 test set and Lang-8 test set show that the proposed algorithm model has significant performance improvement compared with the traditional transformer method and can correct the fluency of sentences. It has good application values. (shrink)

In this paper, the notions of Fα-categorical and Gα-categorical structures are introduced by choosing the isomorphism such that the function itself or its graph sits on the α-th level of the Ershov hierarchy, respectively. Separations obtained by natural graphs which are the disjoint unions of countably many finite graphs. Furthermore, for size-bounded graphs, an easy criterion is given to say when it is computable-categorical and when it is only G2-categorical; in the latter case it is not Fα-categorical for any recursive (...) ordinal α. (shrink)

To address the need for a valid and reliable scale of youth leadership potential based on the development theory of leadership, the current study developed the Youth Leadership Potential Scale (YLPS) and investigated its factor structure and psychometric properties in a sample of 696 students (grades 7-9) in China. Exploratory structural equation modeling (ESEM) identified a five-factor solution comprising leadership information, leadership attitude, communication skills, decision-making skills, and stress management skills. ESEM within confirmatory factor analysis demonstrated an adequate fit for (...) this structure. The scale showed good composite reliability and measurement invariance across different gender and grade/age groups. The scale also showed sufficient concurrent validity with the Coping Self-Efficacy Scale, the Chinese Roets Rating Scale for Leadership, and the Leadership Skills Inventory. Furthermore, criterion-related validity was supported by the relationship between YLPS scores and the length of student leadership positions. The results suggest that the YLPS is a valid and pragmatic measure for assessing youth leadership potential. The current study is the first to develop a youth leadership potential scale based on the development theory of leadership. (shrink)

A growing group of Chinese students is returning to China following graduation, especially young returnees. This group is seen as one of the most innovative sectors of Chinese society. Based on the theory of planned behavior and three kinds of capital theories, this study explores entrepreneurial intention and its influencing factors among Newly Returned Chinese International Students. A survey of 211 NRCIS showed a low level of EI and little knowledge of supporting policies about entrepreneurship. Influencing factors included culture harmony (...) as culture capital, overseas social networks as social capital, and foreign entrepreneurship education and foreign language proficiency as human capital. Attitude mediated the effects of foreign language proficiency, culture harmony, and foreign entrepreneurship education on EI. Perceived behavior control mediated the effect of foreign language proficiency, Chinese language proficiency, culture harmony, foreign entrepreneurship education, domestic entrepreneurship education, and overseas social networks on EI, and subjective norms have no significant mediating effect in any mediation path. Based on these findings, policymakers could pay attention to examining whether the current policies are working and accessible for NRCIS, and domestic entrepreneurship education could keep cultivating students' cross-cultural communication and understanding abilities, and society and education sectors could encourage positive cognition of entrepreneurship and guide students to form a positive attitude toward entrepreneurship and enhance their confidence. (shrink)

Short-term traffic flow prediction is an effective means for intelligent transportation system to mitigate traffic congestion. However, traffic flow data with temporal features and periodic characteristics are vulnerable to weather effects, making short-term traffic flow prediction a challenging issue. However, the existing models do not consider the influence of weather changes on traffic flow, leading to poor performance under some extreme conditions. In view of the rich features of traffic data and the characteristic of being vulnerable to external weather conditions, (...) the prediction model based on traffic data has certain limitations, so it is necessary to conduct research studies on traffic flow prediction driven by both the traffic data and weather data. This paper proposes a combined framework of stacked autoencoder and radial basis function neural network to predict traffic flow, which can effectively capture the temporal correlation and periodicity of traffic flow data and disturbance of weather factors. Firstly, SAE is used to process the traffic flow data in multiple time slices to acquire a preliminary prediction. Then, RBF is used to capture the relation between weather disturbance and periodicity of traffic flow so as to gain another prediction. Finally, another RBF is used for the fusion of the above two predictions on decision level, obtaining a reconstructed prediction with higher accuracy. The effectiveness and robustness of the proposed model are verified by experiments. (shrink)

Though a few scholars have discussed the transnational engagement of Caribbean thinkers with China, hitherto unknown is the imaginative alliance Left-wing Chinese writers crafted with the Caribbean via their works on the Haitian Revolution. This paper explores writings by four Chinese Marxists—Li Chunhui, Wang Chunliang, Lu Guojun, and Mao Xianglin—who engaged with Caribbean intellectuals, like Eric Williams, and used the history of the first anti-colonial revolution to rethink China’s own decolonial experiment. During the Maoist era, these thinkers argued for the (...) independence of the Haitian Revolution from the French Revolution, imagining Haiti’s revolutions as prefigurations of Third-World Revolution. In the deradicalized Deng era, these writers held contradictory stances towards capitalism, stressing how old and neocolonialism plundered Haiti. By reducing Sino-Caribbean relations to the Chinese diaspora in the Caribbean, or to the recent Belt and Road Initiative, scholars overlook lost revolutionary solidarities that aimed to dismantle world white supremacy. (shrink)

Many studies demonstrate that people form their first impression of a stranger based on facial appearance, and these impressions influence their subsequent decisions and behaviors. However, much less research has examined the factors that moderate the accuracy of first impressions based on a photo of face. The present study included three experiments to explore gender differences in the accuracy of impressions based on faces. The results showed that people judge facial attractiveness more accurately for female faces than for male faces (...) while giving more accurate wealth judgments for male faces than for female faces. Interestingly, although we did not find a significant correlation between confidence ratings and the accuracy of wealth rating, we recognized a significant moderate correlation between confidence ratings and the accuracy of attractiveness ratings when female participants rated male faces. To our knowledge, the present study is the first to reveal gender biases in the accuracy of impression judgments based on facial appearance. These findings imply a significant influence of traditional gender roles on accurate facial judgments. (shrink)

Economic and social disruptions of the COVID-19 pandemic have important implications for gender and class inequality. Drawing on Statistics Canada’s monthly Labour Force Survey, we document trends in gender gaps in employment and work hours over the pandemic. Our findings highlight the importance of care provisions for gender equity, with gaps larger among parents than people without children, and most pronounced when care and employment were more difficult to reconcile. When employment barriers eased, so did the gender–employment gap. The pandemic (...) could not undo longer-standing cultural and structural shifts motivating contemporary mothers’ employment. The pandemic also exacerbated educational inequalities among women, highlighting the importance of assessing gendered impacts through an intersectional lens. (shrink)

Industry groups engage in venue shifting when they seek to overturn or alter restrictive regulations imposed by one political venue through another. A critical step in this process is resolving uncertainties surrounding the preference of the targeted venue and the nature of the relevant policy proposal. While existing studies emphasize a long-term trial-and-error process of policy learning, we focus on nascent industries and argue that ventures seek other information sources to resolve these uncertainties quickly. In particular, nascent industry groups are (...) likely to perceive that the targeted venue will support their policy proposal if the targeted venue is ideologically distant from the venue that has enacted the restrictive regulations, if the targeted venue has recently supported other nascent industry groups’ similar policy proposals, or if the industry groups themselves are more exposed to industry peers’ success in promoting the same policy proposal in other jurisdictions. Under these conditions, the industry groups invest more to influence the targeted venue in response to restrictive regulations enacted by other venues. We find support for our theory by examining how from 2013 to 2019 the small unmanned aircraft systems industry trade associations in the United States lobbied state governments to nullify local regulations. (shrink)

A fundamental aspect of human cognition is the ability to parse our constantly unfolding experience into meaningful representations of dynamic events and to communicate about these events with others. How do we communicate about events we have experienced? Influential theories of language production assume that the formulation and articulation of a linguistic message is preceded by preverbal apprehension that captures core aspects of the event. Yet the nature of these preverbal event representations and the way they are mapped onto language (...) are currently not well understood. Here, we review recent evidence on the link between event conceptualization and language, focusing on two core aspects of event representation: event roles and event boundaries. Empirical evidence in both domains shows that the cognitive representation of events aligns with the way these aspects of events are encoded in language, providing support for the presence of deep homologies between linguistic and cognitive event structure. (shrink)

In this paper, we prove that there is a Π01 class in 2ω with a unique nonrecursive member, with that member a cohesive set. This solves an open question from Cenzer. The proof uses the Δ03 method in the context of the construction of a Π01 class.

Decades of empirical and theoretical research has produced an extensive literature on the ethical judgments construct. Given its importance to understanding people’s ethical choices, future research should explore the psychological processes that produce ethical judgments. In this paper, the authors discuss two steps needed to advance this effort. First, they note that the business ethics literature lacks a single, generally accepted definition of ethical judgments. After reviewing several extant definitions, the authors offer a definition of the construct and discuss its (...) advantages. Second, future ethical judgment research would benefit from greater integration between theories of ethical decision making and theories of social cognition. Drawing upon the Hunt–Vitell ( Journal of Macromarketing 6 (Spring), 5–15, 1986 ; In: N. C. Smith and J. A. Quelch (eds.), Ethics in Marketing . Irwin, Homewood, IL, pp. 775–784, 1992 ) model and the heuristic-systematic model (Chaiken, Journal of Personality and Social Psychology 39 (November), 752–766, 1980 ), the authors present a brief research agenda intended to stimulate research on the psychological processes behind ethical judgments. (shrink)

This paper examines the construction of the poet Du Mu’s libertine image to illustrate how Chinese writers and readers of the ninth and tenth centuries validated the search for sensual pleasure by associating it with literary talent, unconventional character, and political disengagement. In doing so, they added indulgence in sensual pleasures to the repertoire of fengliu cultural ideals, a repertoire previously associated with reclusion and drinking. Because sensual pleasure was traditionally viewed as trivial and/or disruptive to social order, ninth-century writers (...) approached the new ideal with considerable ambivalence. Although Du Mu had fashioned a libertine poetic self-image as a young man, he attempted to shed this image later in life. I argue that it was Du Mu’s readers who, by creatively reading his poems and writing anecdotes about his sexual adventures, re-imagined the poet as a figure of fascination and thus created one of the most enduring fengliu characters in Chinese history. (shrink)

Transgressive Typologies: Constructions of Gender and Power in Early Tang China. By Rebecca Doran. Harvard-Yenching Institute Monographs, vol. 103. Cambridge, Mass.: Harvard University Asia Center, Harvard University Press. Pp. viii + 260. $39.95.

Human population genetic research (HPGR) seeks to identify the diversity and variation of the human genome and how human group and individual genetic diversity has developed. This book asks whether developing countries are well prepared for the ethical and legal conduct of human population genetic research, with specific regard to vulnerable target group protection. The book highlights particular issues raised by genetic research on populations as a whole, such as the capacity for current frameworks of Western developed countries to provide (...) adequate protections for target groups in human population genetic research, and explores potential groups of people that may suffer harm in this kind of research. Using The People's Republic of China as a key example, Yue Wang argues that since the target groups of HPGR are almost always vulnerable groups from isolated and rural areas of developing countries, the ethical and legal frameworks for human subject protection need to be reconsidered in order to eliminate, or at least reduce, the vulnerability of those groups. While most research in this field focuses on the impact on individuals, this book breaks new ground in exploring how the interests of target groups are also seriously implicated in genetic work. The book argues that current regulations are far from sufficient to prevent harm to vulnerable groups and puts forward an alternative model for group protection in the context of human population genetic research in developing countries. The book will be of great interest to students and academics of medical law, ethics, and the implications of genetic research. (shrink)

Classification of sciences; Moslem scholars; Africa, North.

本书结合对马克思、恩格斯哲学原著的研究探讨,对大学生们在学习中提出的若干问题进行了阐释。.

Background The enhancement of nursing care quality is closely related to the clinical competence of nurses, making it a crucial component within health systems. Objective The present study investigated the relationship between nurses’ clinical competence, moral identity, and moral injury during the COVID-19 outbreak. Research design This cross-sectional study was carried out among frontline nurses, using the Moral Identity Questionnaire (MIQ), the Moral Injury Symptom Scale-Healthcare Professionals version (MISS-HP), and the Competency Inventory for Registered Nurse (CIRN) as data collection tools. (...) Participants and research context: The research population for this study consisted of all frontline nurses ( n = 251) employed in a hospital in southern Iran. Sampling was conducted between May 1, 2021 and September 30, 2021, during the COVID-19 outbreak. Ethical considerations The present study received approval from the research ethics committee of Rafsanjan University of Medical Sciences, with project No. 99267 and code of ethics ID No. IR. RUMS.REC.1399.262, dated 15.02.2021. Results According to the study findings, 42.2% of the nurses demonstrated high clinical competence, while 51.4% exhibited moderate clinical competence. The results indicated a positive correlation between moral identity and clinical competence but a negative correlation between moral injury and clinical competence. Furthermore, the variables of moral identity and moral injury were found to predict 10% of the variance in clinical competence. Conclusion According to the results, moral identity and moral injury had an impact on the clinical competence of nurses. Therefore, implementing a program aimed at enhancing moral identity and providing training strategies to address moral injury during crises like the COVID-19 pandemic can lead to improvements in nurses’ clinical competence and the overall quality of care they provide. (shrink)