BackgroundPreprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completeness of reporting, as transparency can improve the reader’s ability to independently interpret data and reproduce findings.MethodsIn this observational study, we initially compared independent samples of articles published in bioRxiv and in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed paired comparisons (...) between preprints from bioRxiv to their own peer-reviewed versions in journals.ResultsPeer-reviewed articles had, on average, higher quality of reporting than preprints, although the difference was small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in the independent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easy it was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions did not correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journal publication.ConclusionsOur results suggest that, on average, publication in a peer-reviewed journal is associated with improvement in quality of reporting. They also show that quality of reporting in preprints in the life sciences is within a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea that preprints should be considered valid scientific contributions. (shrink)

It is shown that the Riemannian curvature of the 3-dimensional hypersurfaces in space-time, described by the Wilson loop integral, can be represented by a quaternion quantum operator induced by the SU(2) gauge potential, thus providing a justification for quaternion quantum gravity at the Tev energy scale.

Escritos por onze renomados filósofos os ensaios pretendem, de forma acessível e didática, explicitar as principais tendências e perspectivas da reflexão ética contemporânea. Indicado a estudantes e docentes de filosofia ética, teologia, sociologia e interessados em geral. -/- Prefàcio 1.Tendencias neoaristotelicas na etica atual - Sergio Cremaschi 2. Alasdair MacIntyre e o retorno as tradicoes morais de pesquisa racional - Helder Buenos Aires de Carvalho 3. Etica da finitude - Zeljko Loparic 4. Por uma etica ilustrada e progressista: uma (...) defesa do utilitarismo - Maria Cecilia Maringoni de Carvalho 5. A relacao da filosofia analitica com a teologia moral - Terence Kennedy 6. Rawls: uma teoria etico-politica da justica - Sonia T. Felipe 7. Etica do discurso - F. Javier Herrero 8. Hans Jonas: o principio responsabilidade - Oswaldo Giacoia Junior 9. Etica de coerencia dialetica - Carlos Cirne-Lima 10. Etica intencionalista-teleologica em vittorio hosle - Manfredo Araujo de Oliveira. (shrink)

An admirable introduction to inductive logic, this book is both informative and lucidly written. After an excellent introductory chapter comparing deductive with inductive logic, the author presents Hume's problem of induction and several proposed methods for solving or dissolving it, none of which are adequate. Chapter III is devoted to Goodman's paradox about "grue" and the problems it poses for induction. No attempt, however, is made to develop a calculus of projectibility, which is needed to solve this new riddle of (...) induction. The systematic part of inductive logic is presented in the fourth and longest chapter. This chapter begins with a brief account of elementary truth functions which the author then uses to present an updated and rather elegant version of Mill's methods. The rest of the chapter is devoted to the development of the probability calculus in a systematic manner, without, however, any method of assigning initial probabilities. An account of statistics is appended, which is too brief to be of much value. The fifth chapter is devoted to interpretations of the probability calculus. The frequency interpretation of probability is described as an adequate account of descriptive probability. Two interpretations of inductive probability are presented: Carnap's "logic" interpretation and the frequency interpretation of Reichenbach. Both, however, are found lacking in ultimate justification. Though not flawless, this book is of very high quality.—F. S. M. (shrink)

An updated and extended second edition supporting the findings of its well-known predecessor which claimed that courts employ common-sense notions of causation in determining legal responsibility.

The present essay is organized into five main sections. We begin with a few preliminary remarks about "cloud computing," which are developed more fully in a later section. This is followed by a brief overview of the evolution of Helen Nissenbaum's framework of "privacy as contextual integrity." In particular, we examine Nissenbaum's "Decision Heuristic" model, described in her most recent work on privacy, to see how it enables the contextual-integrity framework to respond to privacy challenges posed by new and emerging (...) technologies. We then apply that heuristic device to questions surrounding one aspect of cloud computing -- viz., "cloud storage" technology. In particular, we focus on current practices affecting Google Docs as an instance of a cloud-storage system. (shrink)

There is a growing literature on the concept of e-trust and on the feasibility and advisability of “trusting” artificial agents. In this paper we present an object-oriented model for thinking about trust in both face-to-face and digitally mediated environments. We review important recent contributions to this literature regarding e-trust in conjunction with presenting our model. We identify three important types of trust interactions and examine trust from the perspective of a software developer. Too often, the primary focus of research in (...) this area has been on the artificial agents and the humans they may encounter after they are deployed. We contend that the humans who design, implement, and deploy the artificial agents are crucial to any discussion of e-trust and to understanding the distinctions among the concepts of trust, e-trust and face-to-face trust. (shrink)

This is an edition of one of the crucial texts of Renaissance scepticism, Quod nihil scitur, by the Portuguese scholar Franciso Sanches. The treatise, first published in 1581, is a refutation of Aaristotelian dialectics and scientific theory in the search for a true scientific method. This volume provides a critical edition of the original text, an English translation, a substantial introduction, and comprehensive annotation.

This study is concerned with certainty and examines the work of Dewey for the light he sheds on this problem. Hart concentrates on the process of verification, the final stage of inquiry in Dewey's theory. He does this because he believes that, according to Dewey, through the process of verification we may attain "flexible" certainty. The first chapter discusses the background of the problem. The second chapter, "A Dewey Dictionary," contains passages selected from Dewey's works on about sixty topics which (...) Hart considers important for his later discussion. In the third chapter, a chronological account of the development of Dewey's theory of inquiry and his views on verification is meticulously presented. The fourth chapter is devoted to a systematic presentation of the place of verification in Dewey's philosophy. In the fifth chapter are the author's critical reflections: Hart holds that the basic principles of Dewey's theory cannot be justified but must be taken on faith. Here Hart does not seem sufficiently appreciative of Dewey's pragmatism. Dewey could answer: such principles are adopted because they are fruitful and will be maintained only so long as they continue to be fruitful. An epilogue concludes the study.—F. S. M. (shrink)

Upshot: In this response, I address the points raised in the commentaries, in particular those related to the scalability and robustness of the mechanism CALM, to its relation with the CAES architecture, and to the transition from sensorimotor to symbolic.