This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6–9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy. Discussions during The Budapest Meeting are reported in depth in this paper as well as the initiatives to involve the participating groups and others in ongoing collaborations with the goal of forming (...) an integrated network of European resources in the fields of ethics of science. (shrink)

This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6–9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy. Discussions during The Budapest Meeting are reported in depth in this paper as well as the initiatives to involve the participating groups and others in ongoing collaborations with the goal of forming (...) an integrated network of European resources in the fields of ethics of science. (shrink)

Bayesian learning theory and evolutionary theory both formalize adaptive competition dynamics in possibly high‐dimensional, varying, and noisy environments. What do they have in common and how do they differ? In this paper, we discuss structural and dynamical analogies and their limits, both at a computational and an algorithmic‐mechanical level. We point out mathematical equivalences between their basic dynamical equations, generalizing the isomorphism between Bayesian update and replicator dynamics. We discuss how these mechanisms provide analogous answers to the challenge of adapting (...) to stochastically changing environments at multiple timescales. We elucidate an algorithmic equivalence between a sampling approximation, particle filters, and the Wright‐Fisher model of population genetics. These equivalences suggest that the frequency distribution of types in replicator populations optimally encodes regularities of a stochastic environment to predict future environments, without invoking the known mechanisms of multilevel selection and evolvability. A unified view of the theories of learning and evolution comes in sight. (shrink)

There are two foundational issues concerning the understanding of life: the investigation of the nature of living organisms and the elucidation of the principles of evolution.

Our ability to successfully fight major challenges of climate change is diminished by rising social and economic inequality. One important source of inequality can be identified in the formula of compound interest which describes unlimited growth of monetary assets and debts based on the law of exponential growth. The paper suggests a novel way to calculate compound interest in times of crisis based on a mechanism that could mitigate the effects of economic competition and help achieve sustainable life on our (...) planet. (shrink)

This is a lovely and very useful book. It deals with the emergence of higher and higher level units of evolution, especially regarding what Queller (1997) called “fraternal major transitions.” These are evolutionary transitions where the lower-level units that gang up are genetically alike and, therefore, the initial advantage is likely to come from the economy of scale rather than the complementation of function, as in the case of “egalitarian transitions.” Simple division of labor may arise from simple conditions (such (...) as some cells being inside, others outside, so that even with the same physiological reactivity the responses of the two cell types may differ), but the spectacular forms arise from evolved epigenetic mechanisms (Jablonka and Lamb 2005). (shrink)

This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6–9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy. Discussions during The Budapest Meeting are reported in depth in this paper as well as the initiatives to involve the participating groups and others in ongoing collaborations with the goal of forming (...) an integrated network of European resources in the fields of ethics of science. (shrink)