Results for 'Enik�� Sepsi'

26 found
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  1.  1
    Simone Weil: Philosophie, Mystique, Esthétique: Actes du Colloque International du Centenaire de Simone Weil, Organisé les 21 Et 22 Janvier à Budapest. [REVIEW]Gizella Gutbrod, Joël Janiaud & Enikő Sepsi (eds.) - 2012 - Archives Karéline.
    De facture classique, la philosophie de Simone Weil ne forme pas moins un ensemble de doctrines qu'unifie une intuition morale de portée métaphysique. La prescription de l'obéissance, de l'humilité, de la pauvreté traduisent une conception du moi qui, ayant une condition métaphysique illégitime de centre du monde, est appelé à renoncer à soi, à s'abandonner. Bref, créature jouissant d'une position usurpée de centre, il ne réalise sa vérité que par la décréation, mettant fin à la prétention d'un individu de valoir (...)
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  2. The SEARCH Neonatal Sepsis Study: Was It Ethical.M. Angell - 2007 - In James V. Lavery (ed.), Ethical Issues in International Biomedical Research: A Casebook. Oxford University Press. pp. 114--116.
     
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  3. Did the SEARCH Neonatal Sepsis Trial Violate the Declaration of Helsinki.Z. A. Bhutta - 2007 - In James V. Lavery (ed.), Ethical Issues in International Biomedical Research: A Casebook. Oxford University Press. pp. 109--113.
     
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  4.  9
    Review of Miklós Vassányi, Enikő Sepsi, and Anikó Daróczi , The Immediacy of Mystical Experience in the European Tradition: Cham, Switzerland: Springer, 2017, ISBN: 978-3-319-45067-4, Hb, Xix+274pp. [REVIEW]Peter Gan - 2018 - Sophia 57 (3):533-534.
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  5.  14
    Hypothesis: L‐Selectin: A Novel Receptor for Lipopolysaccharide and its Potential Role in Bacterial Sepsis.Rajneesh Malhotra & Michael I. Bird - 1997 - Bioessays 19 (10):919-923.
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  6.  6
    Great Idea: What a Fuss About a Swab.Margot R. Brazier - 2020 - Journal of Medical Ethics 46 (8):534-535.
    Developing a simple test to identify swiftly neonates with sepsis who carry the genetic variant which means that one dose of the recommended antibiotic, gentamicin, will cause the child to become profoundly deaf looks like an admirable objective. The baby needs antibiotics and needs them within 1 hour of admission to the neonatal intensive care unit. Conventional genetic tests take much longer to yield results. The test being trialled produces results in 25 min; a baby who carries the variant can (...)
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  7.  17
    Methodological Challenges in European Ethics Approvals for a Genetic Epidemiology Study in Critically Ill Patients: The GenOSept Experience.Ascanio Tridente, Paul A. H. Holloway, Paula Hutton, Anthony C. Gordon, Gary H. Mills, Geraldine M. Clarke, Jean-Daniel Chiche, Frank Stuber, Christopher Garrard, Charles Hinds & Julian Bion - 2019 - BMC Medical Ethics 20 (1):30.
    During the set-up phase of an international study of genetic influences on outcomes from sepsis, we aimed to characterise potential differences in ethics approval processes and outcomes in participating European countries. Between 2005 and 2007 of the FP6-funded international Genetics Of Sepsis and Septic Shock project, we asked national coordinators to complete a structured survey of research ethic committee approval structures and processes in their countries, and linked these data to outcomes. Survey findings were reconfirmed or modified in 2017. Eighteen (...)
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  8.  12
    Ethics Briefing.Martin Davies, Ruth Campbell, Sophie Brannan, Veronica English, Rebecca Mussell & Julian C. Sheather - 2018 - Journal of Medical Ethics 44 (10):725-726.
    The Supreme Court has ruled in the case of Y that there is no requirement to seek the approval of the Court of Protection in decisions to withdraw clinically assisted nutrition and hydration from patients in a prolonged disorder of consciousness.1 Mr Y was 52-year-old man who suffered a cardiac arrest after a myocardial infarction as a result of coronary artery disease. It was not possible to resuscitate him for well over 10 min, resulting in severe cerebral hypoxia which caused (...)
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  9.  3
    Genetic Testing in the Acute Setting: A Round Table Discussion.John Henry McDermott - 2020 - Journal of Medical Ethics 46 (8):531-532.
    Genetic testing has historically been performed in the context of chronic disease and cancer diagnostics. The timelines for these tests are typically measured in days or weeks, rather than in minutes. As such, the concept that genetic information might be generated and then used to alter management in the acute setting has, thus far, not been feasible. However, recent advances in genetic technologies have the potential to allow genetic information to be generated significantly quicker. The m.1555A>G genetic variant is present (...)
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  10.  59
    The Ethics of Paid Plasma Donation: A Plea for Patient Centeredness.Albert Farrugia, Joshua Penrod & Jan M. Bult - 2015 - HEC Forum 27 (4):417-429.
    Plasma protein therapies are a group of essential medicines extracted from human plasma through processes of industrial scale fractionation. They are used primarily to treat a number of rare, chronic disorders ensuing from inherited or acquired deficiencies of a number of physiologically essential proteins. These disorders include hemophilia A and B, different immunodeficiencies and alpha 1-antitrypsin deficiency. In addition, acute blood loss, burns and sepsis are treated by PPTs. Hence, a population of vulnerable and very sick individuals is dependent on (...)
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  11.  4
    Improving Clinical Outcome in Bacteremia.Thomas Herchline & Sheila Gros - 1998 - Journal of Evaluation in Clinical Practice 4 (3):191-195.
  12.  43
    An Apology for Philosophical Transgressions.James W. Heisig - 2017 - European Journal of Japanese Philosophy 2:43-67.
    The essay that follows is, in substance, a lecture delivered in Brussels on 7 December 2016 to the 2nd International Conference of the European Network of Japanese Philosophy. In it I argue that the strategy of qualifying nothingness as an “absolute,” which was adopted by Kyoto School thinkers as a way to come to grips with fundamental problems of Western philosophy, is inherently ambiguous and ultimately weakens the notion of nothingness itself. In its place, a proposal is made to define (...)
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  13.  7
    Ambition, ‘Failure’ and the Laboratory: Birmingham as a Centre of Twentieth-Century British Scientific Psychiatry.Rebecca Wynter - 2021 - British Journal for the History of Science 54 (1):19-40.
    This article will reveal how local scientific determination and ambition, in the face of rejection by funders, navigated a path to success and to influence in national policy and international medicine. It will demonstrate that Birmingham, England's ‘second city’, was the key centre for cutting-edge biological psychiatry in Britain in the 1920s and 1930s. The ambitions of Frederick Mott – doyen of biochemistry, neuropathology and neuropsychiatry, until now celebrated as a London figure – to revolutionize psychiatric treatment through science, chimed (...)
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  14.  7
    A Clinical Case Study That Raised Ethical Issues in a Developing Country.Uchenna Chinweokwu Onubogu - 2019 - Clinical Ethics 14 (3):137-140.
    A 4-day-old female was admitted into a Nigerian Hospital, with neonatal tetanus, jaundice, and sepsis. Four days into the treatment, her clinical condition continued to deteriorate. The family requ...
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  15. Unequal Sample Sizes and the Use of Larger Control Groups Pertaining to Power of a Study.Marie Oldfield - 2016 - Dstl 1 (1).
    To date researchers planning experiments have always lived by the mantra that 'using equal sample sizes gives the best results' and although unequal groups are also used in experimentation, it is not the preferred method of many and indeed actively discouraged in literature. However, during live study planning there are other considerations that we must take into account such as availability of study participants, statistical power and, indeed, the cost of the study. These can all make allocating equal sample sizes (...)
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  16.  14
    Can Health Care Rationing Ever Be Rational?David A. Gruenewald - 2012 - Journal of Law, Medicine and Ethics 40 (1):17-25.
    Mr. M. was a 77-year-old decisionally incapacitated long-term nursing home resident with chronic schizophrenia who was admitted to the hospital with a bacterial pneumonia. His past medical history was notable for deteriorating functional status over the past 2-3 years, urinary retention requiring chronic indwelling bladder catheterization, and two recent hospitalizations for urinary tract infections leading to sepsis. He developed respiratory failure soon after admission and was intubated and placed on mechanical ventilation. Follow-up studies suggested worsening pneumonia and acute respiratory distress (...)
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  17.  6
    Terrible Choices in the Septic Child: A Response to the PALOH Trial Round Table Authors.Joshua Parker & David Wright - 2021 - Journal of Medical Ethics 47 (2):114-116.
    In this response article, we challenge a core assumption that lies at the centre of a round table discussion regarding the Pharmacogenetics to Avoid Loss of Hearing trial. The round table regards a genetic test for a variant that increases the risk of deafness if a carrier is given the antibiotic gentamicin. The idea is that rapid testing can identify neonates at risk, providing an opportunity to prevent giving an antibiotic that might cause deafness. We challenge the assumption that a (...)
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  18. The Grandview Medical Center Bioethics Consultation Service Perspective on the Peril of Isolated and Vulnerable Individuals Due to COVID-19.Jeffrey Kaufhold, Sharon Merryman, Leland Cancilla & Nicholas Salupo - 2021 - Asian Bioethics Review 13 (4):463-471.
    We present the perspective of a Bioethics Consultation Service operating in an urban hospital in Dayton, Ohio, USA, as it adapted to treating Sars-CoV-2 patients throughout 2020. Since the first case of COVID-19 was reported in Ohio on 9 March 2020, until 1 January 2021, the Bioethics Consultation Service was consulted 60 times, a 22.5% increase from the same period of 2019. The most common diagnoses requiring consultation included end-stage renal disease requiring dialysis, out-of-hospital cardiac arrest, and sepsis. Only 10% (...)
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  19.  48
    At the Coalface: For Whom the Bells Knell.Michael Heim - 1988 - Journal of Medical Ethics 14 (3):140.
    A 72-year-old widowed woman known to have an organic brain syndrome was hospitalised owing to gangrene of her lower limbs. The gangrene had been caused by an adduction contracture of her hip resulting in pressure on the medial surface of her left leg. In addition she had pressure sores over both trochanters and the sacrum. The smell of putrefication could be sensed from a distance and on examination large white worms could be seen slithering in the decomposing tissue. The patient (...)
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  20.  14
    Breastfeeding with HIV: An Evidence-Based Case for New Policy.Marielle S. Gross, Holly A. Taylor, Cecilia Tomori & Jenell S. Coleman - 2019 - Journal of Law, Medicine and Ethics 47 (1):152-160.
    To help eliminate perinatal HIV transmission, the US Department of Health and Human Services recommends against breastfeeding for women living with HIV, regardless of viral load or combined antiretroviral therapy status. However, cART radically improves HIV prognosis and virtually eliminates perinatal transmission, and breastfeeding's health benefits are well-established. In this setting, pregnancy is increasing among American women with HIV, and a harm reduction approach to those who breastfeed despite extensive counseling is suggested. We assess the evidence and ethical justification for (...)
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  21.  3
    Is One Narrative Enough? Analytical Tools Should Match the Problems They Address.Nathan Hodson & Susan Bewley - 2021 - Journal of Medical Ethics 47 (5):357-359.
    Jeff Nisker describes his personal experience of a diagnosis of advanced prostate cancer and the kindnesses he received from friendly doctors. He claims that this narrative account supports the promotion of Prostate Specific Antigen screening for asymptomatic men and impugns statisticians, mistakenly thinking that their opposition to PSA screening derives from concerns about financial cost. The account inadvertently demonstrates the danger of over-reliance on a single ethical tool for critical analysis. In the first part of this response, we describe the (...)
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  22.  4
    Clinical Ethics Case Consultation in a University Department of Cardiology and Intensive Care: A Descriptive Evaluation of Consultation Protocols.Michel Noutsias, Daniel Sedding, Jochen Dutzmann, Henning Rosenau, Kim P. Linoh, Nicolas Heirich, Stephan Nadolny, Jan Schildmann & Andre Nowak - 2021 - BMC Medical Ethics 22 (1):1-12.
    BackgroundClinical ethics case consultations provide a structured approach in situations of ethical uncertainty or conflicts. There have been increasing calls in recent years to assess the quality of CECCs by means of empirical research. This study provides detailed data of a descriptive quantitative and qualitative evaluation of a CECC service in a department of cardiology and intensive care at a German university hospital.MethodsSemi-structured document analysis of CECCs was conducted in the period of November 1, 2018, to May 31, 2020. All (...)
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  23.  6
    Drs Bramhall and Bawa-Garba and the Rightful Domain of the Criminal Law.Suzanne Ost - 2019 - Journal of Medical Ethics 45 (3):151-155.
    In the wake of two recent high-profile, controversial cases involving the prosecution and conviction of Drs Bramhall and Bawa-Garba, this article considers when it is socially desirable to criminalise doctors’ behaviour, exploring how the matters of harm, public wrongs and the public interest can play out to justify—or not, as the case may be—the criminal law’s intervention. Dr Bramhall branded his initials on patients’ livers during transplant surgery, behaviour acknowledged not to have caused his patients any harm by way of (...)
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  24.  7
    I Am Not Interested in Talking with You.Adam Peña & Trevor Bibler - 2016 - Hastings Center Report 46 (4):7-9.
    Mr. M is an eighty-five-year-old who presented to the hospital with congestive heart failure exacerbation, pneumonia, altered mental status, and sepsis. A physician determines that he lacks capacity, and the team in the intensive care unit looks to the patient's daughter, Celia, as his surrogate decision-maker because she is named as an agent in his medical power of attorney form. While in the ICU, Mr. M suffers acute respiratory distress secondary to pneumonia and thus requires intubation. Celia accepts several life-sustaining (...)
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  25.  1
    Why Algorithmic Speed Can Be More Important Than Algorithmic Accuracy.Jakob Mainz, Lauritz Munch, Jens Christian Bjerring & Godtfredsen Sissel - forthcoming - Clinical Ethics.
    Artificial Intelligence (AI) often outperforms human doctors in terms of decisional speed. For some diseases, the expected benefit of a fast but less accurate decision exceeds the benefit of a slow but more accurate one. In such cases, we argue, it is often justified to rely on a medical AI to maximize decision speed – even if the AI is less accurate than human doctors.
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  26.  19
    Long‐Term Survival of Intensive Care and Hospital Patient Cohorts Compared with the General Australian Population: A Relative Survival Approach.Dhaval Ghelani, John L. Moran, Andy Sloggett, Richard J. Leeson & Sandra L. Peake - 2009 - Journal of Evaluation in Clinical Practice 15 (3):425-435.