Methodological objectivism is a conception of bias which obscures the contingent and limited nature of methodological principles behind the guise of fixed a priori standards. I suggest as an alternative a more flexible view of the operation of bias which I call the attribution model. The attribution model makes explicit the working principles of both parties to an actual charge of bias. It enables those involved to identify the issues in dispute between them, and is the basis for an approach (...) to handling charges of bias within the process of discussion and negotiation which characterizes normal scientific decision-making. (shrink)

Dr Schaffer outlines the development of the mythological school of European Biblical criticism, especially its German origins and its reception in England, and studies the influence of this movement in the work of specific writers: Coleridge Hölderlin, Browning, and George Eliot. The 'higher criticism' treated sacred scripture as literature and as history, as the product of its time, and the highest expression of a developing group consciousness; it challenged current views on the authorship and dating of the Pentateuch and the (...) Gospels, on inspiration, prophecy, and canonicity, and formulated a new apologetics closely linked with the growth of Romantic aesthetics. The importance of this study is that it shows that readings of specific literary texts can intersect with general movements of thought and action through the scrutiny of a clearly defined intellectual discipline, here the higher criticism, which developed as a particular expression of the larger trends in the history of the period. Dr Shaffer throws light on individual works of literature, the formation between England and Germany, and the bases of European Romanticism. (shrink)

State Medical Boards (SMBs) can take severe disciplinary actions (e.g., license revocation or suspension) against physicians who commit egregious wrongdoing in order to protect the public. However, there is noteworthy variability in the extent to which SMBs impose severe disciplinary action. In this manuscript, we present and synthesize a subset of 11 recommendations based on findings from our team’s larger consensus-building project that identified a list of 56 policies and legal provisions SMBs can use to better protect patients from egregious (...) wrongdoing by physicians. (shrink)

Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...) were younger age and female sex in the United States, and male sex in Mali. Scores in the United States were higher than in Mali (P = 0.005). Despite this difference participants at both sites were well informed overall. Although interpretation must be qualified because questionnaires were not intended as research tools and were not standardized among sites, these results do not support concerns about systematic low understanding among research participants in developing versus developed countries. (shrink)

ABSTRACTPrevious studies have identified two powerful ways to regulate emotional responses to a stressor: experiencing incidental positive emotions and using cognitive reappraisal to reframe the stressor. Several cognitive and motivational theories of positive emotion support the formulation that incidental positive emotions may facilitate cognitive reappraisal. To test the separate and interacting effects of positive emotions and cognitive reappraisal, we first adapted an established picture-based reappraisal paradigm by interspersing blocks of positive emotion inducing and neutral pictures. Across two pre-registered studies, reappraisal (...) effectively decreased self-reported negative emotions and increased self-reported positive emotions; however, experiencing incidental positive emotions did not facilitate reappraisal success. In another preregistered study, we employed a more powerful positive emotion induction via virtual reality, used a social stress anticipation task, and... (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

This paper challenges Williamson's "E = K" thesis on the basis of evidential practice. The main point is that most evidence is only approximately true and so cannot be known if knowledge is factive.

Paradoxes have played an important role both in philosophy and in mathematics and paradox resolution is an important topic in both fields. Paradox resolution is deeply important because if such resolution cannot be achieved, we are threatened with the charge of debilitating irrationality. This is supposed to be the case for the following reason. Paradoxes consist of jointly contradictory sets of statements that are individually plausible or believable. These facts about paradoxes then give rise to a deeply troubling epistemic problem. (...) Specifically, if one believes all of the constitutive propositions that make up a paradox, then one is apparently committed to belief in every proposition. This is the result of the principle of classical logical known as ex contradictione (sequitur) quodlibetthat anything and everything follows from a contradiction, and the plausible idea that belief is closed under logical or material implication (i.e. the epistemic closure principle). But, it is manifestly and profoundly irrational to believe every proposition and so the presence of even one contradiction in one’s doxa appears to result in what seems to be total irrationality. This problem is the problem of paradox-induced explosion. In this paper it will be argued that in many cases this problem can plausibly be avoided in a purely epistemic manner, without having either to resort to non-classical logics for belief (e.g. paraconsistent logics) or to the denial of the standard closure principle for beliefs. The manner in which this result can be achieved depends on drawing an important distinction between the propositional attitude of belief and the weaker attitude of acceptance such that paradox constituting propositions are accepted but not believed. Paradox-induced explosion is then avoided by noting that while belief may well be closed under material implication or even under logical implication, these sorts of weaker commitments are not subject to closure principles of those sorts. So, this possibility provides us with a less radical way to deal with the existence of paradoxes and it preserves the idea that intelligent agents can actually entertain paradoxes. (shrink)

This paper critically explores Timothy Williamson’s view of evidence, and it does so in light of the problem of epistemic luck. Williamson’s view of evidence is, of course, a crucially important aspect of his novel and influential “knowledge-first” epistemological project. Notoriously, one crucial thesis of this project is that one’s evidence is equivalent to what one knows. This has come to be known as the E = K thesis. This paper specifically addresses Williamson’s knowledge-first epistemology and the E = K (...) thesis in the context of anti-luck epistemology and the idea that knowledge is factive. Williamson’s views on these matters are worth investigating in some detail because he subscribes to a well-worked out anti-luck view of knowledge that incorporates what is perhaps the most common anti-luck condition. But this paper is also of more general importance because the critique of Williamson’s views on these matters reveals some important things about the nature of evidence and evidence is one of the most fundamental concepts in epistemology. (shrink)

Recently Timothy Williamson (2007) has argued that characterizations of the standard (i.e. intuition-based) philosophical practice of philosophical analysis are misguided because of the erroneous manner in which this practice has been understood. In doing so he implies that experimental critiques of the reliability of intuition are based on this misunderstanding of philosophical methodology and so have little or no bearing on actual philosophical practice or results. His main point is that the orthodox understanding of philosophical methodology is incorrect in that (...) it treats philosophical thought experiments in such a way that they can be “filled in” in various ways that undermines their use as counter-examples and that intuition plays no substantial role in philosophical practice when we properly understand that methodology as a result of the possibility of such filling in. In this paper Williamson’s claim that philosophical thought experiments cases can be legitimately filled in this way will be challenged and it will be shown that the experimental critique of the intuition-based methods involved a serious issue. (shrink)

It is a commonplace belief that many beliefs, e.g. religious convictions, are a purely private matter, and this is meant in some way to serve as a defense against certain forms of criticism. In this paper it is argued that this thesis is false, and that belief is really often a public matter. This argument, the publicity of belief argument, depends on one of the most compelling and central thesis of Peircean pragmatism. This crucial thesis is that bona fide belief (...) cannot be separated from action. It is then also suggested that we should accept a form of W. K. Clifford's evidentialism. When these theses are jointly accepted in conjunction with the basic principle of ethics that it is prima facie wrong to act in such a way that may subject others to serious but unnecessary and avoidable harm, it follows that many beliefs are morally wrong. (shrink)

The volume opens with selections from Descartes and proceeds in chronological order through the contributions of forty other authors to the philosophy of mind, ending with J. Shaffer's "Could mental states be brain processes?" Other recent contributors include Ryle, Vesey, Smart, Strawson, Wisdom, Campbell, and MacKay. For the combination of the period and perspectives covered, the book is as exhaustive as could be hoped. Vesey's analytical index makes the volume an even more valuable tool for the beginning student.—E. A. (...) R. (shrink)

Objectives: To describe the concerns and priorities of key stakeholders in a developing country regarding ethical obligations held by researchers and perceptions of equity or “what is fair” for study participants in an HIV/AIDS clinical drug trial. Design: Qualitative study with focus groups. Setting: Teaching and referral hospital and rural health centre in western Kenya. Participants: Potential HIV/AIDS clinical trial participants, clinician researchers, and administrators. Results: Eighty nine individuals participated in a total of 11 focus groups over a four month (...) period. The desire for continued drug therapy, most often life long, following an HIV/AIDS clinical trial was the most common priority expressed in all focus groups. Patients with and without HIV/AIDS also thought subsidisation of drug therapies and education were critical forms of compensation for clinical trial participation. Financial incentives were considered important primarily for purchasing drug therapy as well as obtaining food. Patients noted a concern for the potential mismanagement of any money offered. Clinician researchers and administrators felt strongly that researchers have a moral obligation to participants following a trial to provide continued drug therapy, adverse event monitoring, and primary care. Finally, clinician researchers and administrators stressed the need for thorough informed consent to avoid coercion of study participants. Conclusions: Kenyan patients, clinician researchers, and administrators believe that it would be unfair to stop antiretroviral therapy following an HIV/AIDS clinical trial and that researchers have a long term obligation to participants. (shrink)

It is wholly uncontroversial that measurements-or, more properly, propositions that are measurement reports-are often paradigmatically good cases of propositions that serve the function of evidence. In normal cases it is also obvious that stating such a report is an utterly pedestrian case of successful assertion. So, for example, there is nothing controversial about the following claims: (1) that a proposition to the effect that a particular thermometer reads 104C when properly used to determine the temperature of a particular patient is (...) evidence that the patient in question has a fever and (2) that there is nothing wrong with asserting the proposition that a particular thermometer reads 104C for appropriate reasons of communication, etc. when the thermometer has been properly used to determine the temperature of a particular patient. Here it will be shown that Timothy Williamson’s commitments to a number of principles about knowledge and assertion imply that a whole class of utterly ordinary statements like these that are used as evidence are not really evidence because they are not knowledge and so are (perversely) unassertable according to his principled commitments. This paper deals primarily with the second of these two problems and an alternative account of the norms of assertion is introduced which allows for the assertability of such measurement reports. (shrink)

What do the airplane, the escalator, the vacuum cleaner, and the Polaroid camera have in common? It took many, many attempts to perfect these inventions. But the people who invented them persevered and did not give up on their ideas. With TIME For Kids content, this nonfiction book will engage students in reading about inventions as they build their comprehension, vocabulary, and literacy skills. The Reader's Guide and culminating activity direct students back to the text as they develop their higher-order (...) thinking skills. Check It Out! provides resources for additional reading and learning. With text features such as a glossary, index, and table of contents, this book aligns with national and state standards and will keep students engaged in reading. (shrink)

Are moral systems actually impediments to leading a truly good human life? What is good and what is not good? Do we need anyone to tell us these things? With Russ Shaffer-Landau, Bryan Van Norden, and Richard Garner.

This chapter contains sections titled: Mark's Story: ‘It was like Line Dancing for the First Time’ Carl's Story: ‘Everyone Avoids the Front and Center in Class’ Jake's Story: ‘The only Judging going on is in my Own Head’ Competing against their own Bodies (but is it More than a Workout?) Competing against other People (perhaps the Real Competition is within Yourself) Competing against their Own Egos (Playing Nice with your Ego).

This comparative field study evaluated the choices made by U.S., Portuguese, and Hong Kong Chinese evening MBA and graduating university business students when resolving business-related moral dilemmas. The authors developed hypotheses at the country level based on Hofstede’s ratings of each country’s national culture dimensions of power distance, uncertainty avoidance, individualism, and masculinity. The more individualistic U.S. respondents resolved the dilemmas with choices indicating less self-interest and more concern for unidentified others than did their Portuguese and Hong Kong Chinese counterparts, (...) who are from more collectivist societies. The authors discuss implications for future cross-cultural research on business dilemmas and for cooperative interactions among managers from these and other countries. (shrink)

This paper adopts a cognitive linguistic framework to explore the influence of spatial and social factors on the use of Spanish demonstratives esta ‘this’ and esa ‘that’. Twenty adult Spanish speakers in Monterrey, Mexico, were asked questions prompting the selection of puzzle pieces for placement in a 25-piece puzzle located in the shared space between the participant and an addressee. Although participants were not explicitly instructed to produce demonstratives, the need to identify specific puzzle pieces naturally elicited a total of (...) 523 tokens of esta and esa. Analyses of the distribution of esta versus esa show that demonstratives are not used in a categorical manner to mark differences in physical space. Although participants tended to produce proximal esta for referents near the speaker, both esta and esa were used for referents further from the speaker and closer to the addressee. Participants’ demonstrative selection was also influenced by interaction type: intersubjective misalignment between speakers promoted the use of proximal esta, whereas intersubjective alignment promoted the use of distal esa. These results support the view that nominal grounding is an intersubjective activity. Physical and social factors jointly shape speakers’ construal of the developing co-constructed communicative event as a whole, leading to increasingly variable usage of demonstratives as the referent is more distant both spatially and intersubjectively from the speaker. (shrink)

This paper contains a critical examination of the prospects for analyses of knowledge that weaken the factivity condition such that knowledge implies approximate truth.

This article deals with the gamut of international law. Empirical research on international law, charts three main factors—states and bureaucracies, private actors, and international institutions, specifically international tribunals. International law maintains the centrality of the state, which is also the functioning ground for various sub-state structures, governmental actors, and institutions. Private actors such as corporations and non-governmental organizations are instrumental in influencing the construction and outcome of international law. Regarding the relevance of international laws, some opine that while states do (...) infact deliver on obligations, they only choose those that are easy to comply by. Hence, efficiency becomes doubtful. Further, it is claimed that state's compliance only reflects its intentions, not a behavioral shift. These opinions merit questions regarding the relevance of international law. Studies in this field concern, broadly, international human rights law, criminal law, war laws, trade laws, investment law, and regulatory laws. (shrink)

The American Educational Research Association and American Psychological Association published standards for reporting on research. The transparency of reporting measures and data collection is paramount for interpretability and replicability of research. We analyzed 57 articles that assessed alphabet knowledge using researcher-developed measures. The quality of reporting on different elements of AK measures and data collection was not related to the journal type nor to the impact factor or rank of the journal but rather seemed to depend on the individual author, (...) reviewers, and journal editor. We propose various topics related to effective reporting of measures and data collection methods that we encourage the early childhood and literacy communities to discuss. (shrink)

This paper is a response to Baumann's comments on "Can Knowledge Really be Non-fative?" In this paper Baumann's suggestions for how those who deny the factivty of knowledge might deal with the argument from inconsistency and explosion are addressed.

This paper shows how the availability heuristic can be used to justify inference to the best explanation in such a way that van Fraassen's infamous "best of a bad lot" objection can be adroitly avoided. With this end in mind, a dynamic and contextual version of the erotetic model of explanation sufficient to ground this response is presented and defended.

The main question addressed in this paper is whether some false sentences can constitute evidence for the truth of other propositions. In this paper it is argued that there are good reasons to suspect that at least some false propositions can constitute evidence for the truth of certain other contingent propositions. The paper also introduces a novel condition concerning propositions that constitute evidence that explains a ubiquitous evidential practice and it contains a defense of a particular condition concerning the possession (...) of evidence. The core position adopted here then is that false propositions that are approximately true reports of measurements can constitute evidence for the truth of other propositions. So, it will be argued that evidence is only quasi-factive in this very specific sense. (shrink)

This book is a sustained defense of the compatibility of the presence of idealizations in the sciences and scientific realism. So, the book is essentially a detailed response to the infamous arguments raised by Nancy Cartwright to the effect that idealization and scientific realism are incompatible.