Recently developed super‐resolution microscopy techniques are changing our understanding of lipid rafts and membrane organisation in general. The lipid raft hypothesis postulates that cholesterol can drive the formation of ordered domains within the plasma membrane of cells, which may serve as platforms for cell signalling and membrane trafficking. There is now a wealth of evidence for these domains. However, their study has hitherto been hampered by the resolution limit of optical microscopy, making the definition of their properties problematic and contentious. (...) New microscopy techniques circumvent the resolution limit and, for the first time, allow the fluorescence imaging of structures on length scales below 200 nm. This review describes such techniques, particularly as applied to the study of membrane organisation, synthesising newly emerging facets of lipid raft biology into a state‐of‐the art model.Editor's suggested further reading in BioEssays: Super‐resolution imaging prompts re‐thinking of cell biology mechanisms Abstract and Quantitative analysis of photoactivated localization microscopy (PALM) datasets using pair‐correlation analysis Abstract. (shrink)

Owen Flanagan argues in this book for a more psychologically realistic ethical reflection and spells out the ways in which psychology can enrich moral philosophy. Beginning with a discussion of such "moral saints" as Gandhi, Mother Teresa, and Oskar Shindler, Flanagan charts a middle course between an ethics that is too realistic and socially parochial and one that is too idealistic, giving no weight to our natures.

Despite their shared origins, medicine and dentistry are not always two sides of the same coin. There is a long history in medical philosophy of defining disease and various medical models have come into existence. Hitherto, little philosophical and phenomenological work has been done considering dental caries and periodontitis as examples of disease and illness. A philosophical methodology is employed to explore how we might define dental caries and periodontitis using classical medical models of disease – the naturalistic and normativist. (...) We identify shared threads and highlight how the features of these highly prevalent dental diseases prevent them fitting in either definition. The article describes phenomenology and the current thought around the phenomenology of illness, exploring how and why these dental illnesses might integrate into a phenomenological model. We discover that there are some features particular to dental caries and periodontitis: ubiquity, preventability and hyper-monitorablility. Understanding the differences that these dental diseases have compared to many other classically studied diseases leads us to ethical questions concerning how we might manage those who have symptoms and seek treatment. As dental caries and periodontitis are common, preventable and hyper-monitorable, it is suggested that these features affect the phenomenology of these illnesses. For example, if we experience dental illness when we have consciously made decisions that have led to it, do we experience them differently to those rarer illnesses that we cannot expect? Other diseases share these features are discussed. This paper highlights the central differences between the classical philosophical notion of disease in medicine and the dental examples of caries and periodontitis. It suggests that a philosophical method of conceptualising medical illness - phenomenology - should not be applied to these dental illnesses without thought. A phenomenological analysis of any dental illness is yet to be done and this paper highlights why a separate strand of phenomenology should be explored, instead of employing those that are extant. The article concludes with suggestions for further research into the nascent field of the phenomenology of dental illness and aims to act as a springboard to expose the dental sphere to this philosophical method of analysis. (shrink)

The debate between compatibilists and incompatibilists depends in large part on what ordinary people mean by ‘free will’, a matter on which previous experimental philosophy studies have yielded conflicting results. In Nahmias, Morris, Nadelhoffer, and Turner (2005, 2006), most participants judged that agents in deterministic scenarios could have free will and be morally responsible. Nichols and Knobe (2007), though, suggest that these apparent compatibilist responses are performance errors produced by using concrete scenarios, and that their abstract scenarios reveal the folk (...) theory of free will for what it actually is—incompatibilist. Here, we argue that the results of two new studies suggest just the opposite. Most participants only give apparent incompatibilist judgments when they mistakenly interpret determinism to imply that agents’ mental states are bypassed in the causal chains that lead to their behavior. Determinism does not entail bypassing, so these responses do not reflect genuine incompatibilist intuitions. When participants understand what determinism does mean, the vast majority take it to be compatible with free will. Further results indicate that most people’s concepts of choice and the ability to do otherwise do not commit them to incompatibilism, either, putting pressure on incompatibilist arguments that rely on transfer principles, such as the Consequence Argument. We discuss the implications of these findings for philosophical debates about free will, and suggest that incompatibilism appears to be either false, or else a thesis about something other than what most people mean by ‘free will’. (shrink)

Two models of assertion are described and their epistemological implications considered. The assurance model draws a parallel between the ethical norms surrounding promising and the epistemic norms which facilitate the transmission of testimonial knowledge. This model is rejected in favour of the view that assertion transmits knowledge by expressing belief. I go on to compare the epistemology of testimony with the epistemology of memory.

The standard view in epistemology is that propositional knowledge entails belief. Positive arguments are seldom given for this entailment thesis, however; instead, its truth is typically assumed. Against the entailment thesis, Myers-Schulz and Schwitzgebel (Noûs, forthcoming) report that a non-trivial percentage of people think that there can be propositional knowledge without belief. In this paper, we add further fuel to the fire, presenting the results of four new studies. Based on our results, we argue that the entailment thesis does not (...) deserve the default status that it is typically granted. We conclude by considering the alternative account of knowledge that Myers-Schulz and Schwitzgebel propose to explain their results, arguing that it does not explain ours. In its place we offer a different explanation of both sets of findings—the conviction account, according to which belief, but not knowledge, requires mental assent. (shrink)

In recent years, philosophers have identified a number of moral and psychological harms associated with the attention economy (Alysworth & Castro, 2021; Castro & Pham, 2020; Williams, 2018). Missing from many of these accounts of the attention economy, however, is what exactly attention is. As a result of this neglect of the cognitive science of attention, many of these accounts are not empirically credible. They rely on oversimplified and unsophisticated accounts of not only attention, but self- control, and addiction as (...) well. Of note are accounts of the attention economy that rely on the ‘brain disease’ rhetoric of addiction and subsequent control failures (Aylsworth & Castro, 2021; Bhargava & Velasquez, 2021), accounts that rely on a strict dichotomy of top-down vs. bottom-up attention (Williams, 2018; Aylsworth & Castro, 2021), and accounts that construe attention as a limited resource (Williams, 2018). -/- Drawing on recent work from the neuroscience and psychology of attention, I demonstrate the shortcomings of these accounts and sketch a way forward for an empirically grounded account of the attention economy. These accounts tend to uphold strict dichotomies of voluntary control (e.g., compulsion versus choice, dual-process models of self-control, and top-down versus bottom-up) that cannot account for the complexities of attentional control, mental agency, and decision-making. As such, these empirically and conceptually impoverished accounts cannot adequately address the current so-called crisis of attention. To better understand the harms associated with the attention economy, we need an empirically responsible account of the nature and function of attention and mental agency. (shrink)

If someone brings about an outcome without intending to, is she causally and morally responsible for it? What if she acts intentionally, but as the result of manipulation by another agent? Previous research has shown that an agent's mental states can affect attributions of causal and moral responsibility to that agent, but little is known about what effect one agent's mental states can have on attributions to another agent. In Experiment 1, we replicate findings that manipulation lowers attributions of responsibility (...) to manipulated agents. Experiments 2–7 isolate which features of manipulation drive this effect, a crucial issue for both philosophical debates about free will and attributions of responsibility in situations involving social influence more generally. Our results suggest that “bypassing” a manipulated agent's mental states generates the greatest reduction in responsibility, and we explain our results in terms of the effects that one agent's mental states can have on the counterfactual relations between another agent and an outcome. (shrink)

Within philosophy of action, there are three broad views about what, in addition to beliefs, answer the question of “what to do?” and so determine an agent’s motivation: desires, judgments about values/reasons, or states of the will, such as intentions. We argue that recent work in decision theory vindicates the volitionalist. “What to do?” isn’t settled by “what do I value” or “what reasons are there?” Rational motivation further requires determining how to trade off the possibility of a good outcome (...) against the possibility of a bad one—i.e., determining how much of a risk to take. The risk attitudes that embody this tradeoff seem best understood as intentions: as self-governing policies to weight desires or reasons in certain ways. That we need to settle our risk attitudes before making most decisions corroborates Bratman’s claim that self-governing policies are required for resolving impasses of evaluative and normative underdetermination. Moreover, far from being rare or confined to tie-breakings, cases that are underdetermined but for one’s risk attitudes are typical of everyday decision-making. The will is required for most rational action. (shrink)

In a well-known paper, Nick Bostrom presents a confrontation between a fictionalised Blaise Pascal and a mysterious mugger. The mugger persuades Pascal to hand over his wallet by exploiting Pascal's commitment to expected utility maximisation. He does so by offering Pascal an astronomically high reward such that, despite Pascal's low credence in the mugger's truthfulness, the expected utility of accepting the mugging is higher than rejecting it. In this article, I present another sort of high value, low credence mugging. This (...) time, the mugger utilises research on existential risk and the long-term potential of humanity to exploit Pascal's expected-utility-maximising descendant. This mugging is more insidious than Bostrom's original as it relies on plausible facts about the long-term future, as well as realistic credences about how our everyday actions could, albeit with infinitesimally low likelihood, affect the future of humanity. (shrink)

In Measuring the Immeasurable Mind: Where Contemporary Neuroscience Meets the Aristotelian Tradition, Matthew Owen argues that despite its nonphysical character, it is possible to empirically detect and measure consciousness. -/- Toward the end of the previous century, the neuroscience of consciousness set its roots and sprouted within a materialist milieu that reduced the mind to matter. Several decades later, dualism is being dusted off and reconsidered. Although some may see this revival as a threat to consciousness science aimed at (...) measuring the conscious mind, Owen argues that measuring consciousness, along with the medical benefits of such measurements, is not ruled out by consciousness being nonphysical. Owen proposes the Mind-Body Powers model of neural correlates of consciousness, which is informed by Aristotelian causation and a substance dualist view of human nature inspired by Thomas Aquinas, who often followed Aristotle. In addition to explaining why there are neural correlates of consciousness, the model provides a philosophical foundation for empirically discerning and quantifying consciousness. En route to presenting and applying the Mind-Body Powers model to neurobiology, Owen rebuts longstanding objections to dualism related to the mind-body problem. With scholarly precision and readable clarity, Owen applies an oft forgotten yet richly developed historical vantage point to contemporary cognitive neuroscience. (shrink)

The use of drones in public healthcare is suggested as a means to improve efficiency under constrained resources and personnel. This paper begins by framing drones in healthcare as a social experiment where ethical guidelines are needed to protect those impacted while fully realizing the benefits the technology offers. Then we propose an ethical framework to facilitate the design, development, implementation, and assessment of drones used in public healthcare. Given the healthcare context, we structure the framework according to the four (...) bioethics principles: beneficence, non-maleficence, autonomy, and justice, plus a fifth principle from artificial intelligence ethics: explicability. These principles are abstract which makes operationalization a challenge; therefore, we suggest an approach of translation according to a values hierarchy whereby the top-level ethical principles are translated into relevant human values within the domain. The resulting framework is an applied ethics tool that facilitates awareness of relevant ethical issues during the design, development, implementation, and assessment of drones in public healthcare. (shrink)

The first book-length treatment in English of Habermas’s theory of social evolution and progress.

Models of experience -- The interpenetration of concepts and society -- Negativism and truth -- Texture, performativity, and truth -- Aesthetic truth content and oblique second reflection -- Beethoven, proust, and applying adorno's aesthetic theory.

Jacques Lacan's thinking revolutionised the theory and practice of psychoanalysis and had a major impact in fields as diverse as film studies, literary criticism, feminist theory and philosophy. Yet his writings are notorious for their complexity and idiosyncratic style. Emphasising the clinical basis of Lacan's work, _An Introductory Dictionary of Lacanian Psychoanalysis_ is an ideal companion to his ideas for readers in every discipline where his influence is felt. The _Dictionary _features: * over 200 entries, explaining Lacan's own terminology and (...) his use of common psychoanalytic expressions * details of the historical and institutional context of Lacan's work * reference to the origins of major concepts in the work of Freud, Saussure, Hegel and other key thinkers * a chronology of Lacan's life and works. (shrink)

This valuable book will give educators solution-based methods and research-based resources to improve classroom culture, as well as enabling schools to elevate students' engagement and academic achievement.

This paper locates a source of contingency for Leibniz in the fact that God can do otherwise, absolutely speaking. This interpretative line has been previously thought to be a dead-end because it appears inconsistent with Leibniz’s own conception of God, as the ens perfectissimum, or the most perfect being (Adams, 1994). This paper points out that the best argument on offer which seeks to demonstrate this inconsistency fails. The paper then argues that the supposition that God does otherwise implies for (...) Leibniz (at least) that God would not be praiseworthy, which is an absurd implication—or a violation of the principle of sufficient reason (PSR)—but that this is not, strictly speaking, an inconsistency—or a violation of the principle of contradiction (POC). While praiseworthiness is a perfection—and is compossible with God’s other perfections—and so God must instantiate it, this paper argues that, given the nature of praiseworthiness for Leibniz, it in fact makes sense to say that praiseworthiness is merely a contingent perfection of God. (shrink)

I argue that believing that p implies having a credence of 1 in p. This is true because the belief that p involves representing p as being the case, representing p as being the case involves not allowing for the possibility of not-p, while having a credence that’s greater than 0 in not-p involves regarding not-p as a possibility.

Imaginative resistance refers to cases in which one’s otherwise flexible imaginative capacity is constrained by an unwillingness or inability to imaginatively engage with a given claim. In three studies, we explored which specific imaginative demands engender resistance when imagining morally deviant worlds and whether individual differences in emotion predict the degree of this resistance. In Study 1 (N = 176), participants resisted the notion that harmful actions could be morally acceptable in the world of a narrative regardless of the author’s (...) claims about these actions but did not resist imagining that a perpetrator of harm could believe their actions to be morally acceptable. In Study 2 (N = 167) we replicated the findings of Study 1 and showed that imaginative resistance is greatest among participants who experience more negative affect in response to imagining harm and are lower in either trait anxiety or trait psychopathy. In Study 3 (N = 210) we show that this is the case even when the harms assessed include both low-severity (i.e., emotional harm) and high-severity (i.e., killing) cases. Thus, people’s moral beliefs constrain their ability to imagine hypothetical moral alternatives, although this ability systematically varies on the basis of stable individual differences in emotion. (shrink)

This volume seeks to advance and popularise the use of corpus-driven quantitative methods in the study of semantics. The first part presents state-of-the-art research in polysemy and synonymy from a Cognitive Linguistic perspective. The second part presents and explains in a didactic manner each of the statistical techniques used in the first part of the volume. A handbook both for linguists working with statistics in corpus research and for linguists in the fields of polysemy and synonymy.

Was love invented by European poets in the middle ages, as C. S. Lewis claimed, or is it part of human nature? Will winning the lottery really make you happy? Is it possible to build robots that have feelings? These are just some of the intriguing questions explored in this new guide to the latest thinking about the emotions. Drawing on a wide range of scientific research, from anthropology and psychology to neuroscience and artificial intelligence, Emotion: The Science of Sentiment (...) takes the reader on a fascinating journey into the human heart. Illustrating his points with entertaining examples from fiction, film, and popular culture, Dylan Evans ranges from the evolution of the emotions to the nature of love and happiness to the language of feelings, offering readers the most recent thinking on real life topics that touch us all. But Emotion is also a book filled with surprises. Readers will discover, for instance, that the basic emotions are felt the world over--whether we live in the shadow of Times Square or in the depths of the rain forest, we all feel the emotions of disgust, joy, surprise, anger, fear, and distress. We find out that, according to research, winning the lottery does not cause a lasting increase in happiness--a short-lived euphoria is followed in almost every case with a return to our usual emotional state, if not worse. And we meet Kismet, an MIT robot that can express a wide range of emotions, from fear to happiness. Fun to read and based on the latest scientific thinking, here is a stimulating look at our emotions. (shrink)

Nick Bostrom and others have suggested treating decision-making under moral uncertainty as analogous to parliamentary decision-making. The core suggestion of this “parliamentary approach” is that the competing moral theories function like delegates to the parliament, and that these delegates then make decisions by some combination of bargaining and voting. There seems some reason to hope that such an approach might avoid standard objections to existing approaches (for example, the “maximise expected choiceworthiness” (MEC) and “my favourite theory” approaches). However, the parliamentary (...) approach is so far extremely underspecified, making it largely indeterminate how such a model will in fact behave in the respects that those concerned with moral uncertainty care about. This paper explores one way of making it precise. We treat predicaments of moral uncertainty as analogous to bargaining situations alone (setting aside voting), and apply a version of the Nash solution that is standard in bargaining theory. The resulting model does indeed perform in many of the hoped-for ways. However, so also does a version of MEC that employs a structural approach to intertheoretic comparisons. It seems to us an open question which, regarding this version of MEC and the bargaining-theoretic approach, is superior to the other. We identify the key points on which the two differ. (shrink)

In this paper I argue for a doctrine I call ?infallibilism?, which I stipulate to mean that If S knows that p, then the epistemic probability of p for S is 1. Some fallibilists will claim that this doctrine should be rejected because it leads to scepticism. Though it's not obvious that infallibilism does lead to scepticism, I argue that we should be willing to accept it even if it does. Infallibilism should be preferred because it has greater explanatory power (...) than fallibilism. In particular, I argue that an infallibilist can easily explain why assertions of ?p, but possibly not-p? (where the ?possibly? is read as referring to epistemic possibility) is infelicitous in terms of the knowledge rule of assertion. But a fallibilist cannot. Furthermore, an infallibilist can explain the infelicity of utterances of ?p, but I don't know that p? and ?p might be true, but I'm not willing to say that for all I know, p is true?, and why when a speaker thinks p is epistemically possible for her, she will agree (if asked) that for all she knows, p is true. The simplest explanation of these facts entails infallibilism. Fallibilists have tried and failed to explain the infelicity of ?p, but I don't know that p?, but have not even attempted to explain the last two facts. I close by considering two facts that seem to pose a problem for infallibilism, and argue that they don't. (shrink)

In its attempt to deflate of the pretensions of ‘Western knowledge’, the epistemic decolonisation movement carries on the work of Socrates, who sought to persuade those who thought that they were wise but were not, that they were not. Yet in its determination to recover and elevate indigenous systems of thought, decolonisation seems opposed to this very work, which is always corrosive of inherited belief. Decolonisation both expresses and contradicts the spirit of Socratic philosophy.

This chapter contains sections titled: The Problem of Normative Power Consent and Choice Promise, Consent and Normative Interests Permissive Interests.

Robert Pippin's Nietzsche, Psychology, & First Philosophy is a striking, lucid study of Nietzsche's thoughts on the vicissitudes of subjectivity and its constituent commitments. It is an invaluable read not only for Nietzsche specialists, who will find it a serious challenge to prevailing attitudes, but also for all philosophers, who will discover his relevance to contemporary subfields concerned with human intention and action. Nietzsche emerges as the philosopher who came the closest, in the face of the perils of modernity, to (...) offering a radically new picture of what it means to act as a free, authentic subject. (shrink)

This original study examines Jean-François Lyotard's philosophical concept of the differend and details its unexplored implications for literature. it provides a new framework with which to understand the discourse itself, from its Homeric beginnings to postmodern works by authors such as Michael Ondaatje and Jonathan Safran Foer.

By introducing the concept of “mental data,” Palermos (2023) highlights an underappreciated aspect of data ethics that policymakers would do well to heed. Sweeping artificial intelligence (AI) legi...

The most widely endorsed philosophical and scientific theories of consciousness assume that it contributes a single functional capacity to an organism’s information processing toolkit. However, conscious processes are a heterogeneous class of psychological phenomena supported by a variety of neurobiological mechanisms. This suggests a plurality of functional contributions of consciousness (FCCs), in the sense that conscious experience facilitates different functional capacities in different psychological domains. In this paper, I first develop a general methodological framework for isolating the psychological functions that (...) are associated with conscious experience. I then use this to show that the leading accounts—Global Workspace Theories, Higher Order Thought Theory and Information Integration Theory—all fail to acknowledge this functional pluralism, which limits their applicability as theories of consciousness. (shrink)

Virtue ethics prescribes cultivating global and behaviorally efficacious character traits, but John Doris and others argue that situationist social psychology shows this to be infeasible. Here, I show how certain versions of virtue ethics that ‘go mental’ can withstand this challenge as well as Doris’ further objections. The defense turns on an account of which psychological materials constitute character traits and which the situationist research shows to be problematically variable. Many situationist results may be driven by impulsive akrasia produced by (...) low-level , emotionally induced ignorance about one’s situation, and some may be driven by a further subtype: modal akrasia. Many subjects in the infamous Milgram experiments, e.g., seem to have recognized what the virtuous thing to do was and that they should do it, and only failed to do it because their emotions prevented them from seeing that they could. If the primary constituents of character traits are higher-level mental dispositions involved in deliberation, though, then the results don’t show that these psychological materials are problematically variable. (shrink)

Studying Lacan's Seminar VII offers a contemporary, critically informed set of analyses of Lacan's ethics seminar and astute reflections about what Lacan's ethics offers to the field of psychoanalytic thought today. The volume interrogates the seminar with fresh voices and situated curiosities and perspectives, making for a compellingly exciting range of explorations of the crucial matters related to an ethics of psychoanalysis. The essays question and tease out the paradoxes Lacan draws attention to in his seminar of 1959-1960, and in (...) addition, offer radical engagements with the seminar in light of theories of racism, inequality, capitalism, education, and subjectivity. The key elements in Lacan's seminar are explained, debated, and reconsidered with Antigone, das Ding, and the inevitable "ne ceder pas sur son desir" duly unpacked, examined, and ruminated upon. Studying Lacan's Seminar VII will be of interest to psychoanalytic scholars and students of Lacanian psychoanalysis, as well as psychoanalytic therapists and analysts. It will also be of interest to scholars and students of politics, philosophy, and studies at the intersections of racism, film, feminism, sociology, gender and queer theory. (shrink)

A historical review -- Contemplative practices in higher education -- Challenges and replies to contemplative methods -- Contemplative research -- The contemplative mind : a vision of higher education for the 21st century.

Many contemporary philosophers argue that assertion is governed by an epistemic norm. In particular, many defend the knowledge account of assertion, which says that one should assert only what one knows. Here, I defend a non‐normative alternative to the knowledge account that I call the repK account of assertion. According to the repK account, assertion represents knowledge, but it is not governed by a constitutive epistemic rule. I show that the repK account offers a more straightforward interpretation of the conversational (...) patterns and intuitions that motivate the knowledge account. It does so in terms of ordinary normative principles that philosophers already accept, none of which are constitutive to assertion. I then contend that the repK account is preferable to the knowledge account because it is simpler, its implications are less contentious, and it avoids a problem for normative accounts of assertion recently raised by Peter Pagin. I also argue that the repK account offers a satisfying explanation of selfless assertion, a counterexample to the knowledge account posed by Jennifer Lackey. (shrink)

Peter Carruthers argues that the global workspace theory implies there are no facts of the matter about animal consciousness. The argument is easily extended to other cognitive theories of consciousness, posing a general problem for consciousness studies. But the argument proves too much, for it also implies that there are no facts of the matter about human consciousness. A key assumption of the argument is that scientific theories of consciousness must explain away the explanatory gap. I criticize this assumption and (...) point to an alternative strategy for defending scientific theories of consciousness, one that better reflects the ongoing scientific practice. I argue there are introspectable inferential connections from phenomenal concepts to functional concepts that scientists can use to individuate the global workspace in terms of capacities that animals and humans share. (shrink)

Many philosophers and psychologists now argue that emotions play a vital role in reasoning. This paper explores one particular way of elucidating how emotions help reason which may be dubbed ?the search hypothesis of emotion?. After outlining the search hypothesis of emotion and dispensing with a red herring that has marred previous statements of the hypothesis, I discuss two alternative readings of the search hypothesis. It is argued that the search hypothesis must be construed as an account of what emotions (...) typically do, rather than as a definition of emotion. Even as an account of what emotions typically do, the search hypothesis can only be evaluated in the context of a specific theory of what emotions are. 1 Introduction 2 The search hypothesis of emotion 3 A red herring: the frame problem 4 The search problem 5 Two readings of the search hypothesis 6 Two final remarks 7 Conclusion. (shrink)

This chapter contains sections titled: Learning Difference Against Ignoring Difference I Am Because We Are and We Are Because I Am Practicing Just Parenting Teaching Alienation? Notes.

Abstract In this paper, I take exception with a widely held philosophical doctrine, according to which agents are morally responsible only for actions they have intentionally done, or chosen to bring about. I argue that that there are positive duties of consideration and proper regard that make sense of holding persons responsible in the absence of any choice to commit wrong acts.