Background and purposeThis study aimed to analyze the feasibility and safety of endovascular therapy (EVT) in patients with acute posterior circulation stroke and vertebrobasilar dolichoectasia (VBD).Materials and methodsBASILAR was a national prospective registry of consecutive patients with symptomatic and imaging-confirmed acute stroke in the posterior circulation within 24 h of symptom onset. We evaluated EVT feasibility and safety in patients with VBD. Primary outcomes included improvement in modified Rankin Scale scores (mRS) at 90 days and mortality within 90 days. The (...) secondary outcome was the rate of favorable functional outcome, defined as mRS ≤ 3 (indicating independent ambulation) at 90 days. Safety outcomes included surgery-related complications and other serious adverse events.ResultsA total of 534 cases were included: 159 with VBD and 375 controls. No significant difference in mRS at 90 days was found between groups, but patients with VBD had a higher baseline National Institutes of Health Stroke Scale (NIHSS) score [30 (19–33) vs. 25 (15–32)] and were older [65 (59–74) vs. 63 (55–72) year]. After propensity score matching, there were no significant differences in baseline NIHSS score between the two groups, and the efficacy and safety of EVT were similar between patients with or without VBD. Furthermore, the prognostic effect of puncture-to-recanalization time on the probability of mortality within 90 days in EVT-treated patients with VBD was significant {adjusted odds ratio, 1.008 [95% confidence interval (1.001–1.015)]}.ConclusionEndovascular therapy is safe and feasible in patients with acute posterior circulation stroke and VBD. The puncture-to-recanalization time is important for predicting the prognosis of EVT-treated patients with VBD. (shrink)

Abstract:Retro-writing has ethical implications. How a speaking subject applies a retro-perspective frames a piece of writing within certain cultural discourses. In contemporary Chinese poetry, cultural nostalgia and the attempted revival of ancient aesthetics is a complex issue, one that is largely the result of a general interest in cultural archeology, writers’ anxiety of influence, the desire to escape from various political pressures, and the claim of a need for a distinctive Chinese cultural identity. The subject in many contemporary Chinese poems, (...) in many cases, is a male subject striving to retrieve the premodern holistic state of being, which is illusory. Han Bo’s two poems “Modern Sex Machine” and “Mass(ive) Killing Machine” are unique in that they examine the bludgeoning of modernity within postmodern parameters and attempt to map the dynamics of modern and contemporary subjecthood, which is in fact a transcorporeal experience of the subject as that which is, ultimately, subjectless. Such work, in creating a cross-corporeal subjectless subject, embraces alterity and renders possibilities for the reader to reject a prior unitary transcendental subject that is illusory, and thereby to discover the beings of themselves and their roles in the world—and to extend this work of reconfiguring subjecthood from literature into other aspects of social life. (shrink)

Retro-writing has ethical implications. How a speaking subject applies a retro-perspective frames a piece of writing within certain cultural discourses. In contemporary Chinese poetry, cultural nostalgia and the attempted revival of ancient aesthetics is a complex issue, one that is largely the result of a general interest in cultural archeology, writers’ anxiety of influence, the desire to escape from various political pressures, and the claim of a need for a distinc­tive Chinese cultural identity. The subject in many contemporary Chinese poems, (...) in many cases, is a male subject striving to retrieve the premodern holistic state of being, which is illusory. Han Bo’s two poems “Modern Sex Machine” and “Mass Killing Machine” are unique in that they examine the bludgeoning of modernity within postmodern parameters and attempt to map the dynamics of modern and contemporary subjecthood, which is in fact a transcorporeal experience of the subject as that which is, ultimately, subjectless. Such work, in creating a cross-corporeal subjectless subject, embraces alterity and renders possibilities for the reader to reject a prior unitary transcendental subject that is illusory, and thereby to discover the beings of themselves and their roles in the world—and to extend this work of reconfiguring subjecthood from literature into other aspects of social life. (shrink)

The processing of words in sentence reading is influenced by both information from sentential context and information from previewing upcoming words, but how both effects interact during online reading is not clear. In this study, we tested the interaction of predictability effect and the preview effect in predicting reading processing. In the experiment, sentence constraint was controlled using all high-constraint sentences as materials. We manipulated both the predictability of the target word in the sentence and the semantic relationship between the (...) preview word and the target word as predictors of the semantic preview effect. The results showed that the semantic preview effect was present only when the target word had low-predictability in the sentence but was not observed when the target word had high-predictability in the sentence. The results suggest that contextual information in reading can modulate the pre-activation of words and thus influence whether the preview word has a priming effect. The results of this study provide further evidence that reading comprehension involves an interactive system of processing multiple sources of information at multiple levels. (shrink)

Urban space is the spatial projection of various social and economic activities. Given the complexity of urban functions and the ongoing expansion of urban areas, the spatial differentiation of various economic activities within cities tends to become more and more clear; moreover, there tends to be spatial inequalities in resource allocation. Taking Beijing as an example, this study develops a spatial accessibility model at the town level by integrating the spatial distribution of economic activities with the transport system and evaluating (...) the accessibility to various economic activities. The equality of the residents’ economic-related travel activity is also evaluated in line with the population distribution. The results show that the accessibility to economic activities generally decreases in going from the urban center to the peripheral suburbs, and this “core to edge” difference is readily apparent. In general, residents tend to choose areas to settle in which have a high degree of accessibility, however, the attractiveness of accessibility is constrained within certain limits, as evidenced by a reduction of population in the center of Beijing. Additionally, there are inequalities with respect to traveling experiences. For instance, 27.8% of residents experience very convenient travel conditions, mostly in the Xicheng, Dongcheng, and Haidian districts, and this equates to a high level of accessibility; about half of the residents in Beijing live in areas ranked as being of medium accessibility and where the distribution of economic activities and transportation facilities are insufficient. Residents living in the outlying Changping, Mentougou, Shunyi, and Fangshan districts have relatively poor access to transportation indicating a low level of accessibility. Overall, the evaluation method for spatial equality considers comprehensively the distribution of economic activities, transportation, and population distribution and can provide a reference framework for optimization of the urban spatial structure to improve urban spatial equality. (shrink)