The arising of smart cities has shown the limitations of the traditional attempts to understand and characterize cities. The smart city marks a relevant step in the evolution of urban systems which is expected to have disruptive impacts in the near future. Indeed, the ‘smartness’ qualification of cities points to relevant changes in the possibilities these complex systems offer mainly due to changes in the information which is made available. This chapter studies the notion of city from an ontological viewpoint, (...) and provides the first elements of a general framework aimed to characterize and unify how to understand the city and its evolution. It starts from historical considerations to isolate the factors that drove the changes from ancient to modern cities, and the complexity that characterizes the nature of cities. Our analysis departs from the traditional views and leads to distinguish three ontological components in the city: the modified physical place, the distributed agentivity, and the knowledge present in the system. The analysis of these components and their interactions, we argue, provides a coherent reading of the city across its evolution steps, and may be used to establish the maturity of today’s smart cities. (shrink)

The field of bioethics is increasingly coming into contact with empirical research findings. In this article, we ask what role empirical research can play in the process of ethical clarification and decision-making. Ethical reflection almost always proceeds in three steps: the description of the moral question,the assessment of the moral question and the evaluation of the decision-making. Empirical research can contribute to each step of this process. In the description of the moral object, first of all, empirical research has a (...) role to play in the description of morally relevant facts. It plays a role in answering the “reality-revealing questions” (what, why,how, who, where and when), in assessing the consequences and in proposing alternative courses of action. Secondly, empirical research plays a role in assessing the moral question. It must be acknowledged that research possesses “the normative power of the factual,” which can also become normative by suppressing other norms. However, inductive normativity should always be balanced out by a deductive form of normativity. Thirdly, empirical research also has a role to play in evaluating the decision-making process. It can rule out certain moral choices by pointing out the occurrence of certain unexpected consequences or effects. It can also be useful, however, as a sociology of bioethics in which the discipline of bioethics itself becomes an object of research. (shrink)

Objectives: The objective of this research is to analyse the evolution and nature of published empirical research in the fields of medical ethics and bioethics.Design: Retrospective quantitative study of nine peer reviewed journals in the field of bioethics and medical ethics .Results: In total, 4029 articles published between 1990 and 2003 were retrieved from the journals studied. Over this period, 435 studies used an empirical design. The highest percentage of empirical research articles appeared in Nursing Ethics , followed by the (...) Journal of Medical Ethics and the Journal of Clinical Ethics . These three journals account for 84.1% of all empirical research in bioethics published in this period. The results of the χ2 test for two independent samples for the entire dataset indicate that the period 1997–2003 presented a higher number of empirical studies than did the period 1990–1996 . This increase is statistically significant . Most empirical studies employed a quantitative paradigm . The main topic of research was prolongation of life and euthanasia .Conclusions: We conclude that the proportion of empirical research in the nine journals increased steadily from 5.4% in 1990 to 15.4% in 2003. It is likely that the importance of empirical methods in medical ethics and bioethics will continue to increase. (shrink)

Critical Theory: The Key Concepts introduces over 200 widely-used terms, categories and ideas drawing from new historicism, postmodernism, psychoanalysis, Marxism, narratology and other approaches. Entries range from concise definitions to longer explanatory essays and include terms such as :EgoDesireConsumptionHypertextKitschMisogynyQueer StudiesSymbolSuperstructureRaceFeaturing cross-referencing throughout, a substantial bibliography and index, this accessible and easy-to-use guide is an invaluable introduction for anyone studying critical theory.

What contribution can visual art practice bring to interdisciplinary research? And how to give an account of practice-led research that acknowledges the need for interdisciplinary intelligibility? I consider these two questions by reflecting on the methodology--which I call "critical practical analogy" (CPA)--that I have developed while investigating the metaethical implications of French philosopher Simone Weil's notion of attention, during my practice-led PhD. In order to address the first question, I consider as a case study a research art project that employs (...) CPA, and I explain how CPA proved instrumental in overcoming the impasse that I reached by purely theoretical investigation of Weil's discourse on attention and how it opened a distinctly artistic way forward in my research. In order to address the second question, I consider a problem posed by the interdisciplinary nature of my research (covering art and philosophy). I show how, through the application of CPA to the case study, I articulated an exegesis of my research that was intelligible across these two heterogeneous fields of investigation. In conclusion, I give some reasons for my hope that CPA may possess some heuristic and exegetical applicability in practice-led interdisciplinary research beyond my own research. (shrink)

This book is intended as a historical and critical study on the origin of the equations of motion as established in Newton's Principia. The central question that it aims to answer is whether it is indeed correct to ascribe to Galileo the inertia principle and the law of falling bodies. In order to accomplish this task, the study begins by considering theories on the motion of bodies from classical antiquity, and especially those of Aristotle. The theories developed during the Middle (...) Ages and the Renaissance are then reviewed, with careful analysis of the contributions of, for example, the Merton and Parisian Schools and Galileo's immediate predecessors, Tartaglia and Benedetti. Finally, Galileo's work is examined in detail, starting from the early writings. Excerpts from individual works are presented, to allow the texts to speak for themselves, and then commented upon. The book provides historical evidence both for Galileo's dependence on his forerunners and for the major breakthroughs that he achieved. It will satisfy the curiosity of all who wish to know when and why certain laws have been credited to Galileo. (shrink)

ABSTRACTSince its origin, bioethics has attracted the collaboration of few social scientists, and social scientific methods of gathering empirical data have remained unfamiliar to ethicists. Recently, however, the clouded relations between the empirical and normative perspectives on bioethics appear to be changing. Three reasons explain why there was no easy and consistent input of empirical evidence into bioethics. Firstly, interdisciplinary dialogue runs the risk of communication problems and divergent objectives. Secondly, the social sciences were absent partners since the beginning of (...) bioethics. Thirdly, the meta‐ethical distinction between ‘is’ and ‘ought’ created a ‘natural’ border between the disciplines. Now, bioethics tends to accommodate more empirical research. Three hypotheses explain this emergence. Firstly, dissatisfaction with a foundationalist interpretation of applied ethics created a stimulus to incorporate empirical research in bioethics. Secondly, clinical ethicists became engaged in empirical research due to their strong integration in the medical setting. Thirdly, the rise of the evidence‐based paradigm had an influence on the practice of bioethics. However, a problematic relationship cannot simply and easily evolve into a perfect interaction. A new and positive climate for empirical approaches has arisen, but the original difficulties have not disappeared. (shrink)

Approximately a quarter of a billion people around the world suffer from malaria each year. Most cases are located in sub-Saharan Africa where Anopheles gambiae mosquitoes are the principal vectors of this public health problem. With the use of CRISPR-based gene drives, the population of mosquitoes can be modified, eventually causing their extinction. First, we discuss the moral status of the organism and argue that using genetically modified mosquitoes to combat malaria should not be abandoned based on some moral value (...) of A. gambiae. Secondly, we argue that environmental impact studies should be performed to obtain an accurate account of the possible effects of a potential eradication of the organism. However, the risks from the purposeful extinction of A. gambiae should not overtake the benefits of eradicating malaria and risk assessments should be used to determine acceptable risks. Thirdly, we argue that the eventual release of the genetically modified mosquitoes will depend on transparency, community involvement, and cooperation between different nations. (shrink)

In Boccacio's Decameron, Cervigni sees a parodic echo of the circles of Dante's Divine Comedy, and asks whether Bocaccio envisions the voyage of the brigata as similar to Dante the Pilgrim's journey toward the center, first the abysmal center of Lucifer, then towards the highest center, God.

This book describes in detail the various theories on the shape of the Earth from classical antiquity to the present day and examines how measurements of its form and dimensions have evolved throughout this period. The origins of the notion of the sphericity of the Earth are explained, dating back to Eratosthenes and beyond, and detailed attention is paid to the struggle to establish key discoveries as part of the cultural heritage of humanity. In this context, the roles played by (...) the Catholic Church and the philosophers of the Middle Ages are scrutinized. Later contributions by such luminaries as Richer, Newton, Clairaut, Maupertuis, and Delambre are thoroughly reviewed, with exploration of the importance of mathematics in their geodetic enterprises. The culmination of progress in scientific research is the recognition that the reference figure is not a sphere but rather a geoid and that the earth’s shape is oblate. Today, satellite geodesy permits the solution of geodetic problems by means of precise measurements. Narrating this fascinating story from the very beginning not only casts light on our emerging understanding of the figure of the Earth but also offers profound insights into the broader evolution of human thought. (shrink)

This article discusses the relation between empirical and normative approaches in bioethics. The issue of dwarf tossing, while admittedly unusual, is chosen as a point of departure because it challenges the reader to look with fresh eyes upon several central bioethical themes, including human dignity, autonomy, and the protection of vulnerable people. After an overview of current approaches to the integration of empirical and normative ethics, we consider five ways that the empirical and normative can be brought together to speak (...) to the problem of dwarf tossing: prescriptive applied ethics, theoretical ethics, critical applied ethics, particularist ethics and integrated empirical ethics. We defend a position of critical applied ethics that allows for a two-way relation between empirical and normative theories. Against efforts fully to integrate the normative and the empirical into one synthesis, we propose that the two should stand in tension and relation to one another. The approach we endorse acknowledges that a social practice can and should be judged both by the gathering of empirical data and by normative ethics. Critical applied ethics uses a five stage process that includes: (a) determination of the problem, (b) description of the problem, (c) empirical study of effects and alternatives, (d) normative weighing and (e) evaluation of the effects of a decision. In each stage, we explore the perspective from both the empirical (sociological) and the normative ethical point of view. We conclude by applying our five-stage critical applied ethics to the example of dwarf tossing. (shrink)

This article examines Paul Guyer’s claim that we should attempt to ground the principle of religious freedom on the basis of Kant’s arguments for religious liberty. I problematise Guyer’s suggestion by investigating a hypothetical ‘dogmatic conflict’ between a scientifically and a religiously grounded belief. I further suggest that considering Christian Wolff’s philosophy might provide us with an approach which shares the benefits that Guyer identifies in Kant, while at the same time avoiding the issues Kant might run into that result (...) from the occurrence of the dogmatic conflict. I start by providing a background to Wolff’s philosophy and explaining the notion of the dogmatic conflict. Then I present a potential contemporary case of the dogmatic conflict and try to see how it would be dealt with based on Guyer’s proposal. Finally, I consider what a Wolffian solution would look like, arguing that Guyer’s project might benefit from considering Wolff. (shrink)

This paper presents Christian Wolff’s claim that philosophy, undertaken on the basis of a proper method, cannot contradict revealed religion. The paper first provides a context of Wolff’s banishment from Halle for holding views in conflict with religious doctrines. Next, it proceeds, on the basis of Wolff’s Discursus præliminaris de philosophia in genere prefixed to his 1728 Latin Logic, to explain the principles of Wolff’s method, and to show how his conception of method enables him to disallow the possibility of (...) a genuine conflict between philosophical and religious dogmas. For Wolff, doctrinal conflicts between philosophy and revealed religion can only occur as a result of terminological disagreements, disagreements between dogmas and hypotheses, or disagreements between dogmas and theological misinterpretations. The actual conflict of dogmas, understood as religious or philosophical truths, Wolff holds to be impossible. (shrink)

This thesis investigates the development of ontology as a philosophical discipline in the German philosophical tradition. It starts from what can be considered the invention of ontology and proceeds to the way it was received in the philosophy of Hegel. It is separated into two parts. The first part argues that what can be called the ‘traditional’ form of ontology is developed by Christian Wolff in his 1730 monograph Philosophia prima sive Ontologia, and it traces both the history of the (...) name ‘ontology’, as well as the history of the conception which led to Wolff’s formulation of it. The history of the name tracks the use of the concept ‘ontology’ from its first occurrence in 1606 up to Wolff. The history of the conception tracks the conceptions of various philosophical disciplines, found in thinkers such as Aristotle, Aquinas, and Spinoza, that ultimately give rise to Wolff’s conception of ontology as a science of an entity qua entity. The second part traces the development of this Wolffian conception through the philosophical systems of Kant and Hegel. The aim of this thesis is to argue that Wolff’s philosophy should be seen as the original formulation of the philosophical discipline of ontology and that the Wolffian conception of ontology is the one shared by subsequent German thinkers up to, and including, Hegel. I refer to this shared understanding of what ontology is as ‘the German ontological tradition’. The title of the thesis, The Possibility of Ontology, refers to the way in which this traditional understanding of what ontology is, is treated throughout the German ontological tradition. Specifically, Kant argues that the traditional conception is effectively impossible, while in Hegel one can find arguments that are intended to show that some aspects of this traditional discipline are in fact possible. Besides focusing on a fairly under-researched topic of the early history of ontology as a philosophical discipline, this thesis attempts to utilise its historical findings in order to provide novel ways in which the systems of the thinkers such as Kant and Hegel can be understood. There is a serious disregard for, or underplaying of, the Wolffian influence on the philosophical thought of Kant and Hegel, and it is my aim to contribute to the rectification of this situation by demonstrating the frequently overlooked dialogue these thinkers had with Wolff’s conception of ontology. (shrink)

We study the bi-embeddability and elementary bi-embeddability relation on graphs under Borel reducibility and investigate the degree spectra realized by these relations. We first give a Borel reduction from embeddability on graphs to elementary embeddability on graphs. As a consequence we obtain that elementary bi-embeddability on graphs is a $\boldsymbol {\Sigma }^1_1$ complete equivalence relation. We then investigate the algorithmic properties of this reduction. We obtain that elementary bi-embeddability on the class of computable graphs is $\Sigma ^1_1$ complete with respect (...) to computable reducibility and show that the elementary bi-embeddability and bi-embeddability spectra realized by graphs are related. (shrink)

The origin of the genetic code has been attributed in part to an accidental assignment of codons to amino acids. Although several lines of evidence indicate the subsequent expansion and improvement of the genetic code, the hypothesis of Francis Crick concerning a frozen accident occurring at the early stage of genetic code evolution is still widely accepted. Considering Crick’s hypothesis, mathematical descriptions of hypothetical scenarios involving a huge number of possible coexisting random genetic codes could be very important to explain (...) the origin and evolution of a selected genetic code. This work aims to contribute in this regard, that is, it provides a theoretical framework in which statistical parameters of error functions are calculated. Given a genetic code and an amino acid property, the functional code robustness is estimated by means of a known error function. In this work, using analytical calculations, general expressions for the average and standard deviation of the error function distributions of completely random codes with standard stop codons were obtained. As a possible biological application of these results, any set of amino acids and any pure or mixed amino acid properties can be used in the calculations, such that, in case of having to select a set of amino acids to create a genetic code, possible advantages of natural selection of the genetic codes could be discussed. (shrink)

Since its origin, bioethics has attracted the collaboration of few social scientists, and social scientific methods of gathering empirical data have remained unfamiliar to ethicists. Recently, however, the clouded relations between the empirical and normative perspectives on bioethics appear to be changing. Three reasons explain why there was no easy and consistent input of empirical evidence into bioethics. Firstly, interdisciplinary dialogue runs the risk of communication problems and divergent objectives. Secondly, the social sciences were absent partners since the beginning of (...) bioethics. Thirdly, the meta‐ethical distinction between ‘is’ and ‘ought’ created a ‘natural’ border between the disciplines. Now, bioethics tends to accommodate more empirical research. Three hypotheses explain this emergence. Firstly, dissatisfaction with a foundationalist interpretation of applied ethics created a stimulus to incorporate empirical research in bioethics. Secondly, clinical ethicists became engaged in empirical research due to their strong integration in the medical setting. Thirdly, the rise of the evidence‐based paradigm had an influence on the practice of bioethics. However, a problematic relationship cannot simply and easily evolve into a perfect interaction. A new and positive climate for empirical approaches has arisen, but the original difficulties have not disappeared. (shrink)

BackgroundCurrent preimplantation genetic testing (PGT) technologies enable embryo genotyping across the whole genome. This has led to the development of polygenic risk scoring of human embryos (PGT-P). Recent implementation of PGT-P, including screening for intelligence, has been extensively covered by media reports, raising major controversy. Considering the increasing demand for assisted reproduction, we evaluated how information about PGT-P is communicated in press media and explored the diversity of ethical themes present in the public debate.MethodsLexisNexis Academic database and Google News were (...) searched to identify articles about polygenic embryo screening. This led to 535 news articles. 59 original articles met the inclusion criteria. Inductive content analysis was used to analyse these articles.Results8.8% of articles gave embryo polygenic scoring a positive portrayal, while 36.8% expressed a negative attitude. 54.4% were neutral, mostly highlighting limited practical value of the technology in in vitro fertilization settings. We identified five main ethical themes that are also present in academic literature and the broader debate on reproductive technologies: a slippery slope towards designer babies, well-being of the child and parents, impact on society, deliberate choice and societal readiness.ConclusionsImplementation of embryo polygenic profiling engenders a need for specific recommendations. Current media analysis discloses important ethical themes to consider when creating future guidelines for PGT-P. (shrink)

Participation in healthcare decision-making is considered to be an important right of minors, and is highlighted in both international legislation and public policies. However, despite the legal recognition of children’s rights to participation, and also the benefits that children experience by their involvement, there is evidence that legislation is not always translated into healthcare practice. There are a number of factors that may impact on the ability of the child to be involved in decisions regarding their medical care. Some of (...) these factors relate to the child, including their capacity to be actively involved in these decisions. Others relate to the family situation, sociocultural context, or the underlying beliefs and practices of the healthcare provider involved. In spite of these challenges to including children in decisions regarding their clinical care, we argue that it is an important factor in their treatment. The extent to which children should participate in this process should be determined on a case-by-case basis, taking all of the potential barriers into account. (shrink)

The new wave of ‘foundation models’—general-purpose generative AI models, for production of text (e.g., ChatGPT) or images (e.g., MidJourney)—represent a dramatic advance in the state of the art for AI. But their use also introduces a range of new risks, which has prompted an ongoing conversation about possible regulatory mechanisms. Here we propose a specific principle that should be incorporated into legislation: that any organization developing a foundation model intended for public use must demonstrate a reliable detection mechanism for the (...) content it generates, as a condition of its public release. The detection mechanism should be made publicly available in a tool that allows users to query, for an arbitrary item of content, whether the item was generated (wholly or partly) by the model. In this paper, we argue that this requirement is technically feasible and would play an important role in reducing certain risks from new AI models in many domains. We also outline a number of options for the tool’s design, and summarize a number of points where further input from policymakers and researchers would be required. (shrink)

Il termineha cominciato a essere impiegato nel nostro paese con riferimento all'integrazione sociale di gruppi minoritari solo a partire dagli anni sessanta, per sostituire il concetto ormai logoro di. Prendendo in esame le piů recenti normative italiane ed europee l'articolo mostra come le nuove politiche disegnino un ritorno, al di sotto di una terminologia rimasta immutata, alla concettualitÀ assimilazionista. Questo ritorno, in controtendenza rispetto alla progressiva giuridificazione e proceduralizzazione dell'appartenenza messa in moto dall'emergere nel secondo dopoguerra della politica dei diritti (...) umani, sembra spingere le nostre societÀ politiche indietro verso una pericolosa ri-sostanzializzazione del concetto di cittadinanza in un processo che, lungi dall'aprire spazi di convivenza culturalmente plurali, sembra condurre concretamente verso una sempre piů spregiudicata e discriminante selezione migratoria funzionale a perpetuare quella sistematica inferiorizzazione economica e simbolica degli immigrati in cui consiste e di cui si nutre il razzismo istituzionale europeo. (shrink)

The debate over the genetic testing of minors has developed into a major bioethical topic. Although several controversial questions remain unanswered, a degree of consensus has been reached regarding the policies on genetic testing of minors. Recently, several commentators have suggested that these policies are overly restrictive, too narrow in focus, and even in conflict with the limited empirical evidence that exists on this issue. We respond to these arguments in this paper, by first offering a clarification of three key (...) concepts—autonomy of the minor, future autonomy, and parental authority—which must be disentangled. We then respond to the arguments by noting the uncertainty of the value of predictive genetic information, and by assessing the psychosocial risks still involved in genetic testing of minors, which are also largely unknown. We conclude that the current consensus position is justified at this stage, in light of the predictions of harm resulting from genetic testing of minors that have not been adequately proved to be unwarranted. (shrink)

Developing World Bioethics, Volume 22, Issue 1, Page 15-22, March 2022.