Results for 'Device Approval '

994 found
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  1.  31
    Unregulated Health Research Using Mobile Devices: Ethical Considerations and Policy Recommendations.Mark A. Rothstein, John T. Wilbanks, Laura M. Beskow, Kathleen M. Brelsford, Kyle B. Brothers, Megan Doerr, Barbara J. Evans, Catherine M. Hammack-Aviran, Michelle L. McGowan & Stacey A. Tovino - 2020 - Journal of Law, Medicine and Ethics 48 (S1):196-226.
    Mobile devices with health apps, direct-to-consumer genetic testing, crowd-sourced information, and other data sources have enabled research by new classes of researchers. Independent researchers, citizen scientists, patient-directed researchers, self-experimenters, and others are not covered by federal research regulations because they are not recipients of federal financial assistance or conducting research in anticipation of a submission to the FDA for approval of a new drug or medical device. This article addresses the difficult policy challenge of promoting the welfare and (...)
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  2.  83
    Ethical challenges with the left ventricular assist device as a destination therapy.Aaron G. Rizzieri, Joseph L. Verheijde, Mohamed Y. Rady & Joan L. McGregor - 2008 - Philosophy, Ethics, and Humanities in Medicine 3:1-15.
    The left ventricular assist device was originally designed to be surgically implanted as a bridge to transplantation for patients with chronic end-stage heart failure. On the basis of the REMATCH trial, the US Food and Drug Administration and the US Centers for Medicare & Medicaid Services approved permanent implantation of the left ventricular assist device as a destination therapy in Medicare beneficiaries who are not candidates for heart transplantation. The use of the left ventricular assist device as (...)
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  3.  10
    Riegel v. Medtronic, Inc.: Revisiting Pre-Emption for Medical Devices.Bruce Patsner - 2009 - Journal of Law, Medicine and Ethics 37 (2):305-317.
    The pre-emption doctrine as applied to food and drug law argues that manufacturers whose products gain Food and Drug Administration marketing approval are immune from tort liability in state court solely on the basis of their FDA approval. This pre-emption protection applies both to claims of direct damages caused by the product and as well as indirect damages claims.The recent 8-1 U.S. Supreme Court decision in Riegel v. Medtronic, Inc. upheld the manufacturer’s contention that the pre-emption provision in (...)
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  4.  23
    Informed consent and compulsory medical device registries: ethics and opportunities.Daniel B. Kramer & Efthimios Parasidis - 2022 - Journal of Medical Ethics 48 (2):79-82.
    Many high-risk medical devices earn US marketing approval based on limited premarket clinical evaluation that leaves important questions unanswered. Rigorous postmarket surveillance includes registries that actively collect and maintain information defined by individual patient exposures to particular devices. Several prominent registries for cardiovascular devices require enrolment as a condition of reimbursement for the implant procedure, without informed consent. In this article, we focus on whether these registries, separate from their legal requirements, have an ethical obligation to obtain informed consent (...)
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  5.  18
    Riegel v. Medtronic, Inc.: Revisiting Pre-emption for Medical Devices.Bruce Patsner - 2009 - Journal of Law, Medicine and Ethics 37 (2):305-317.
    The recent United States Supreme Court decision in Riegel v. Medtronic, Inc. affirmed the doctrine of pre-emption protection only for those medical devices reaching U.S. markets via the PMA process and preserved the previous Lohr v. Medtronic decision's lack of preemption protection for those medical devices marketed via the generally more abbreviated 510 clearance mechanism. This paper reviews the logic and faults of the Riegel decision and discusses the implications of the Riegel decision for pre-emption protection for other classes of (...)
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  6.  5
    Why-UD? Assessing the requirement to trial an intrauterine device as a condition for elective sterilisation in female patients.Teresa Baron - forthcoming - Journal of Medical Ethics.
    Some National Health Service healthcare boards in the UK will approve a request for female sterilisation only if the patient first accepts a trial period of 1 year with an intrauterine device (IUD), a form of long-acting reversible contraception. In this article, I argue that this requirement is not justified by appeal to any of (or any combination of) promotion of informed consent, paternalistic concerns regarding patient regret in later life and health service budgetary considerations. Informed consent and patient (...)
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  7.  28
    Ethical and regulatory implications of the COVID-19 pandemic for the medical devices industry and its representatives.Guy Maddern, Bernadette Richards, Robyn Clay-Williams, Katrina Hutchison, Quinn Grundy, Jane Johnson, Wendy Rogers & Brette Blakely - 2022 - BMC Medical Ethics 23 (1):1-7.
    The development and deployment of medical devices, along with most areas of healthcare, has been significantly impacted by the COVID-19 pandemic. This has had variable ethical implications, two of which we will focus on here. First, medical device regulations have been rapidly amended to expedite approvals of devices ranging from face masks to ventilators. Although some regulators have issued cessation dates, there is inadequate discussion of triggers for exiting these crisis standards, and evidence that this may not be feasible. (...)
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  8.  8
    Opinions among pediatric critical care physicians regarding the ethics of withdrawal of ventricular assist devices and extracorporeal membrane oxygenation.Antonia A. Melas, Leanna L. Huard, Rong Guo & Robert B. Kelly - forthcoming - Clinical Ethics:147775092110015.
    Background Pediatric critical care physician attitudes about withdrawal of ventricular assist devices and extracorporeal membrane oxygenation in cases of medical futility are poorly defined. Our aim was to define current attitudes regarding the withdrawal of these devices. Methods IRB-approved, cross-sectional observational survey conducted among pediatric critical care attending physicians and fellow physicians in the United States between 2016 and 2017. Data was collected anonymously and statistically analyzed. Results A total of 158 physicians responded with 67% being attending physicians. Compared to (...)
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  9.  72
    Vioxx and other pharmaceutical product withdrawals: ethical issues in ensuring the integrity of drug and medical device research, development and commercialization.K. L. Phua & F. I. Achike - 2007 - Clinical Ethics 2 (3):155-162.
    The Vioxx drug recall and other cases of withdrawals of approved pharmaceutical products as a result of reports of serious harm to users indicate that there are many problems associated with the process of getting these products to the end user the ordinary person in the street. The problems include those related to drug/medical device research and development, clinical trials, presentation and publication of research results, approval by regulatory authorities, preparation of clinical practice guidelines, marketing of products by (...)
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  10.  2
    Kritika Fulerovog shvatanja prirodnog prava.Dejan Dević - 2007 - Beograd: Službeni glasnik.
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  11.  24
    A clinical trials manual from the Duke Clinical Research Institute: lessons from a horse named Jim.Margaret B. Liu - 2010 - Hoboken, NJ: Wiley-Blackwell. Edited by Kate Davis & Margaret B. Liu.
    As the_number of clinical trials continues to grow, there is an increasing need for education and training in the field. The clinical research climate is less forgiving of errors and oversights and therefore requires more knowledge of regulations and requirements. This brand new edition details new laws and regulations in protecting children participating in clinical trials and how a new focus on privacy of individual health information in the United States has changed how medical records are handled. Includes a manual (...)
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  12.  30
    Perspectives on informed assent and bodily integrity in prospective deep brain stimulation for youth with refractory obsessive-compulsive disorder.Jared N. Smith, Natalie Dorfman, Meghan Hurley, Ilona Cenolli, Kristin Kostick-Quenet, Gabriel Lazaro-Munoz, Eric A. Storch & Jennifer Blumenthal-Barby - forthcoming - Clinical Ethics.
    BackgroundDeep brain stimulation is approved for treating refractory obsessive-compulsive disorder in adults under the US Food and Drug Administration Humanitarian Device Exemption, and studies hav...
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  13.  18
    Asking questions that matter – Question prompt lists as tools for improving the consent process for neurotechnology clinical trials.Andreas Schönau, Sara Goering, Erika Versalovic, Natalia Montes, Tim Brown, Ishan Dasgupta & Eran Klein - 2022 - Frontiers in Human Neuroscience 16.
    Implantable neurotechnology devices such as Brain Computer Interfaces and Deep Brain Stimulators are an increasing part of treating or exploring potential treatments for neurological and psychiatric disorders. While only a few devices are approved, many promising prospects for future devices are under investigation. The decision to participate in a clinical trial can be challenging, given a variety of risks to be taken into consideration. During the consent process, prospective participants might lack the language to consider those risks, feel unprepared, or (...)
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  14. Authentic faith and acknowledged risk: dissolving the problem of faith and reason.Daniel J. McKaughan - 2013 - Religious Studies 49 (1):101-124.
    One challenge to the rationality of religious commitment has it that faith is unreasonable because it involves believing on insufficient evidence. However, this challenge and influential attempts to reply depend on assumptions about what it is to have faith that are open to question. I distinguish between three conceptions of faith each of which can claim some plausible grounding in the Judaeo-Christian tradition. Questions about the rationality or justification of religious commitment and the extent of compatibility with doubt look different (...)
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  15. Higher-Order Epistemic Attitudes and Intellectual Humility.Allan Hazlett - 2012 - Episteme 9 (3):205-223.
    This paper concerns would-be necessary connections between doxastic attitudes about the epistemic statuses of your doxastic attitudes, or ‘higher-order epistemic attitudes’, and the epistemic statuses of those doxastic attitudes. I will argue that, in some situations, it can be reasonable for a person to believe p and to suspend judgment about whether believing p is reasonable for her. This will set the stage for an account of the virtue of intellectual humility, on which humility is a matter of your higher-order (...)
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  16. Empirical tests of interest-relative invariantism.Chandra Sekhar Sripada & Jason Stanley - 2012 - Episteme 9 (1):3-26.
    According to Interest-Relative Invariantism, whether an agent knows that p, or possesses other sorts of epistemic properties or relations, is in part determined by the practical costs of being wrong about p. Recent studies in experimental philosophy have tested the claims of IRI. After critically discussing prior studies, we present the results of our own experiments that provide strong support for IRI. We discuss our results in light of complementary findings by other theorists, and address the challenge posed by a (...)
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  17. How to Use the Experience Machine.Eden Lin - 2016 - Utilitas 28 (3):314-332.
    The experience machine was traditionally thought to refute hedonism about welfare. In recent years, however, the tide has turned: many philosophers have argued not merely that the experience machine doesn't rule out hedonism, but that it doesn't count against it at all. I argue for a moderate position between those two extremes: although the experience machine doesn't decisively rule out hedonism, it provides us with some reason to reject it. I also argue for a particular way of using the experience (...)
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  18. The Non-Conceptuality of the Content of Intuitions: A New Approach.Clinton Tolley - 2013 - Kantian Review 18 (1):107-36.
    There has been considerable recent debate about whether Kant's account of intuitions implies that their content is conceptual. This debate, however, has failed to make significant progress because of the absence of discussion, let alone consensus, as to the meaning of ‘content’ in this context. Here I try to move things forward by focusing on the kind of content associated with Frege's notion of ‘sense ’, understood as a mode of presentation of some object or property. I argue, first, that (...)
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  19. From Justified Emotions to Justified Evaluative Judgements.Julien A. Deonna & Fabrice Teroni - 2012 - Dialogue 51 (1):55-77.
    ABSTRACT: Are there justified emotions? Can they justify evaluative judgements? We first explain the need for an account of justified emotions by emphasizing that emotions are states for which we have or lack reasons. We then observe that emotions are explained by their cognitive and motivational bases. Considering cognitive bases first, we argue that an emotion is justified if and only if the properties the subject is aware of constitute an instance of the relevant evaluative property. We then investigate the (...)
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  20. Justification as 'Would-Be' Knowledge.Aidan McGlynn - 2012 - Episteme 9 (4):361-376.
    In light of the failure of attempts to analyse knowledge as a species of justified belief, a number of epistemologists have suggested that we should instead understand justification in terms of knowledge. This paper focuses on accounts of justification as a kind of ‘would-be’ knowledge. According to such accounts a belief is justified just in case any failure to know is due to uncooperative external circumstances. I argue against two recent accounts of this sort due to Alexander Bird and Martin (...)
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  21. Kant on Radical Evil and the Origin of Moral Responsibility.Irene McMullin - 2013 - Kantian Review 18 (1):49-72.
    The notion of radical evil plays a more important role in Kant's moral theory than is typically recognized. In Religion Within the Limits of Mere Reason, radical evil is both an innate propensity and a morally imputable act – a paradoxical status that has prompted commentators to reject it as inconsistent with the rest of Kant's moral theory. In contrast, I argue that the notion of radical evil accounts for the beginning of moral responsibility in Kant's theory, since the act (...)
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  22.  12
    Closed-Loop Neuromodulation and Self-Perception in Clinical Treatment of Refractory Epilepsy.Tobias Haeusermann, Cailin R. Lechner, Kristina Celeste Fong, Alissa Bernstein Sideman, Agnieszka Jaworska, Winston Chiong & Daniel Dohan - 2023 - American Journal of Bioethics Neuroscience 14 (1):32-44.
    Background: Newer “closed-loop” neurostimulation devices in development could, in theory, induce changes to patients’ personalities and self-perceptions. Empirically, however, only limited data of patient and family experiences exist. Responsive neurostimulation (RNS) as a treatment for refractory epilepsy is the first approved and commercially available closed-loop brain stimulation system in clinical practice, presenting an opportunity to observe how conceptual neuroethical concerns manifest in clinical treatment. Methods: We conducted ethnographic research at a single academic medical center with an active RNS treatment program (...)
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  23.  56
    The pure theory of public justification.Steven Wall - 2016 - Social Philosophy and Policy 32 (2):204-226.
    :The ideal of public justification holds, at a minimum, that the most fundamental political and legal institutions of a society must be publicly justified to each of its members. This essay proposes and defends a new account of this ideal. The account defended construes public justification as an ideal of rational justification, one that is grounded in the moral requirement to respect the rational agency of persons. The essay distinguishes two kinds of justifying reasons that bear on politics and shows (...)
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  24.  24
    Off-Label Prescribing: A Call for Heightened Professional and Government Oversight.Rebecca Dresser & Joel Frader - 2009 - Journal of Law, Medicine and Ethics 37 (3):476-486.
    Under current U.S. law, physicians may prescribe drugs and devices in situations not covered on the label approved by the Food and Drug Administration. Those supporting this system say that requiring FDA approval for off-label uses would unnecessarily impede the delivery of benefits to patients. Patients do benefit from off-label prescribing that is supported by sound scientific and medical evidence. In the absence of such evidence, however, off-label prescribing can expose patients to risky and ineffective treatments. The medical community (...)
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  25.  10
    Off-Label Prescribing: A Call for Heightened Professional and Government Oversight.Rebecca Dresser & Joel Frader - 2009 - Journal of Law, Medicine and Ethics 37 (3):476-486.
    Off-label prescribing is an integral part of contemporary medicine. Many patients benefit when they receive drugs or devices under circumstances not specified on the label approved by the Food and Drug Administration. An off-label use may provide the best available intervention for a patient, as well as the standard of care for a particular health problem. In oncology, pediatrics, geriatrics, obstetrics, and other practice areas, patient care could not proceed without off-label prescribing. When scientific and medical evidence justify off-label uses, (...)
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  26.  46
    Gender Bias in Medical Implant Design and Use: A Type of Moral Aggregation Problem?Katrina Hutchison - 2019 - Hypatia 34 (3):570-591.
    In this article, I describe how gender bias can affect the design, testing, clinical trials, regulatory approval, and clinical use of implantable devices. I argue that bad outcomes experienced by women patients are a cumulative consequence of small biases and inattention at various points of the design, testing, and regulatory process. However, specific instances of inattention and bias can be difficult to identify, and risks are difficult to predict. This means that even if systematic gender bias in implant design (...)
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  27. Should Utilitarianism Be Scalar?Gerald Lang - 2013 - Utilitas 25 (1):80-95.
    Scalar utilitarianism, a form of utilitarianism advocated by Alastair Norcross, retains utilitarianism's evaluative commitments while dispensing with utilitarianism's deontic commitments, or its commitment to the existence or significance of moral duties, obligations and requirements. This article disputes the effectiveness of the arguments that have been used to defend scalar utilitarianism. It is contended that Norcross's central ‘Persuasion Argument’ does not succeed, and it is suggested, more positively, that utilitarians cannot easily distance themselves from deontic assessment, just as long as scalar (...)
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  28. Practial reasoning, decision theory and anti-intellectualism.Jessica Brown - 2012 - Episteme 9 (1):1-20.
    In this paper, I focus on the most important form of argument for anti-intellectualism, one that exploits alleged connections between knowledge and practical reasoning. I first focus on a form of this argument which exploits a universal principle, Sufficiency, connecting knowledge and practical reasoning. In the face of putative counterexamples to Sufficiency, a number of authors have attempted to reformulate the argument with a weaker principle. However, I argue that the weaker principles suggested are also problematic. I conclude that, so (...)
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  29. When may we kill government agents? In defense of moral parity.Jason Brennan - 2016 - Social Philosophy and Policy 32 (2):40-61.
    :This essay argues for what may be called the parity thesis: Whenever it would be morally permissible to kill a civilian in self-defense or in defense of others against that civilian's unjust acts, it would also be permissible to kill government officials, including police officers, prison officers, generals, lawmakers, and even chief executives. I argue that in realistic circumstances, violent resistance to state injustice is permissible, even and perhaps especially in reasonably just democratic regimes. When civilians see officials about to (...)
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  30.  54
    Making the Ideal Real: Publicity and Morality in Kant.Melissa Zinkin - 2016 - Kantian Review 21 (2):237-259.
    This article discusses the concept of publicity in Kant’s moral philosophy. Insofar as the concepts of ‘public’ and ‘private’ can describe our relations with others, they can be considered to be moral concepts. I argue that we can find in Kant a moral duty not to keep our maxims of action private, or secret. Whereas Korsgaard argues that sometimes in the face of evil it is permissible to sidestep the moral law, I argue that it is rather through publicity that (...)
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  31.  50
    Meta-induction in epistemic networks and the social spread of knowledge.Gerhard Schurz - 2012 - Episteme 9 (2):151-170.
    Indicators of the reliability of informants are essential for social learning in a society that is initially dominated by ignorance or superstition. Such reliability indicators should be based on meta-induction over records of truth-success. This is the major claim of this paper, and it is supported in two steps. One needs a non-circular justification of the method of meta-induction, as compared to other learning methods. An approach to this problem has been developed in earlier papers and is reported in section (...)
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  32.  26
    Decisional nonconsequentialism and the risk sensitivity of obligation.Horacio Spector - 2016 - Social Philosophy and Policy 32 (2):91-128.
    :A good deal of contemporary moral nonconsequentialism assumes that agents have perfect knowledge about the various features and consequences of their options. This assumption is unrealistic. More often than not, moral agents can only assess with a certain degree of probability the factual circumstances that are morally relevant for their decision making. My aim in this essay is to discuss the problem of moral decisions under risk from the point of view of nonconsequentialism. Basically, I analyze how objective moral principles (...)
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  33. Freedom, Knowledge and Affection: Reply to Hogan.Nicholas Stang - 2013 - Kantian Review 18 (1):99-106.
    In a recent paper, Desmond Hogan aims to explain how Kant could have consistently held that noumenal affection is not only compatible with noumenal ignorance but also with the claim that experience requires causal affection of human cognitive agents by things in themselves. Hogan's argument includes the premise that human cognitive agents have empirical knowledge of one another's actions. Hogan's argument fails because the premise that we have empirical knowledge of one another's actions is ambiguous. On one reading, the argument (...)
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  34.  47
    Blueprint for Transparency at the U.S. Food and Drug Administration: Recommendations to Advance the Development of Safe and Effective Medical Products.Joshua M. Sharfstein, James Dabney Miller, Anna L. Davis, Joseph S. Ross, Margaret E. McCarthy, Brian Smith, Anam Chaudhry, G. Caleb Alexander & Aaron S. Kesselheim - 2017 - Journal of Law, Medicine and Ethics 45 (s2):7-23.
    BackgroundThe U.S. Food and Drug Administration traditionally has kept confidential significant amounts of information relevant to the approval or non-approval of specific drugs, devices, and biologics and about the regulatory status of such medical products in FDA’s pipeline.ObjectiveTo develop practical recommendations for FDA to improve its transparency to the public that FDA could implement by rulemaking or other regulatory processes without further congressional authorization. These recommendations would build on the work of FDA’s Transparency Task Force in 2010.MethodsIn 2016-2017, (...)
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  35. Responsibility and the value of choice.T. M. Scanlon - 2013 - Think 12 (33):9-16.
    ExtractImagine that you are struggling to finish a project, with the deadline fast approaching. Nearly done, you are about to print out what you have finished when a dialog box appears on your computer screen telling you that you must download and install an update for some piece of software. Frustrated, you try to make it go away, but it keeps reappearing. So you relent and click on ‘Install’, and your screen is filled with small print listing ‘Terms and Conditions’. (...)
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  36.  73
    Transcranial magnetic stimulation: a historical evaluation and future prognosis of therapeutically relevant ethical concerns.Jared C. Horvath, Jennifer M. Perez, Lachlan Forrow, Felipe Fregni & Alvaro Pascual-Leone - 2011 - Journal of Medical Ethics 37 (3):137-143.
    Transcranial Magnetic Stimulation (TMS) is a non-invasive neurostimulatory and neuromodulatory technique increasingly used in clinical and research practices around the world. Historically, the ethical considerations guiding the therapeutic practice of TMS were largely concerned with aspects of subject safety in clinical trials. While safety remains of paramount importance, the recent US Food and Drug Administration approval of the Neuronetics NeuroStar TMS device for the treatment of specific medication-resistant depression has raised a number of additional ethical concerns, including marketing, (...)
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  37. The normative standing of group agents.Rachael Briggs - 2012 - Episteme 9 (3):283-291.
    Christian List and Philip Pettit argue that groups of people can be agents – beings that believe, desire and act. Their account combines a non-reductive realist view of group attitudes, on which groups literally have attitudes that cannot be analyzed in terms of the attitudes of their members, with methodological individualism, on which good explanations of group-level phenomena should not posit forces above individual attitudes and behaviors. I then discuss the main normative conclusion that LP draw from the claim that (...)
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  38. Personhood, animals, and the law.Christine M. Korsgaard - 2013 - Think 12 (34):25-32.
    ExtractThe idea that all the entities in the world may be, for legal and moral purposes, divided into the two categories of ‘persons’ and ‘things’ comes down to us from the tradition of Roman law. In the law, a ‘person’ is essentially the subject of rights and obligations, while a thing may be owned as property. In ethics, a person is an object of respect, to be valued for her own sake, and never to be used as a mere means (...)
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  39.  51
    When Scientists Deceive: Applying the Federal Regulations.Collin C. O'Neil & Franklin G. Miller - 2009 - Journal of Law, Medicine and Ethics 37 (2):344-350.
    Deception is a useful methodological device for studying attitudes and behavior, but deceptive studies fail to fulfill the informed consent requirements in the U.S. federal regulations. This means that before they can be approved by Institutional Review Boards, they must satisfy the four regulatory conditions for a waiver or alteration of these requirements. To illustrate our interpretation, we apply the conditions to a recent study that used deception to show that subjects judged the same wine as more enjoyable when (...)
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  40. Eternity, knowledge, and freedom.Joseph Diekemper - 2013 - Religious Studies 49 (1):45-64.
    This article addresses the problem of divine foreknowledge and human freedom by developing a modified version of Boethius' solution to the problem – one that is meant to cohere with a dynamic theory of time and a conception of God as temporal. I begin the article by discussing the traditional Boethian solution, and a defence of it due to Kretzmann and Stump. After canvassing a few of the objections to this view, I then go on to offer my own modified (...)
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  41. Social justice, genomic justice and the veil of ignorance: Harsanyi meets Mendel.Samir Okasha - 2012 - Economics and Philosophy 28 (1):43-71.
    John Harsanyi and John Rawls both used the veil of ignorance thought experiment to study the problem of choosing between alternative social arrangements. With his ‘impartial observer theorem’, Harsanyi tried to show that the veil of ignorance argument leads inevitably to utilitarianism, an argument criticized by Sen, Weymark and others. A quite different use of the veil-of-ignorance concept is found in evolutionary biology. In the cell-division process called meiosis, in which sexually reproducing organisms produce gametes, the chromosome number is halved; (...)
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  42. A glass half-full: Brian Skyrms's signals.Kim Sterelny - 2012 - Economics and Philosophy 28 (1):73-86.
    ExtractBrian Skyrms's Signals has the virtues familiar from his Evolution of the Social Contract and The Stag Hunt. He begins with a very simple model of agents in interaction, and in a series of brief and beautifully clear chapters, this model and its successors are explored, elaborated, connected and illustrated through biological theory and the social sciences. Signals borrows its core model from David Lewis: it is Lewis's signalling game. In this game, two agents interact. One agent can observe which (...)
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  43.  95
    Group agency and epistemic dependency.Aaron Dewitt - 2012 - Episteme 9 (3):235-244.
    Modern epistemic questions have largely been focused around the individual and her ability to acquire knowledge autonomously. More recently epistemologists have begun to look more broadly in providing accounts of knowledge by considering its social context, where the individual depends on others for true beliefs. Hardwig explains the effect of this shift starkly, arguing that to reject epistemic dependency is to deny certain true beliefs widely held throughout society and, more specifically, it is to deny that science and scholarship can (...)
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  44.  32
    RAC Oversight of Gene Transfer Research: A Model Worth Extending?Nancy M. P. King - 2002 - Journal of Law, Medicine and Ethics 30 (3):381-389.
    Clinical gene transfer research has both a unique history and a complex and layered system of research oversight, featuring a unique review body, the Recombinant DNA Advisory Committee. This paper briefly describes the process of decision-making about clinical GTR, considers whether the questions, problems, and issues raised in clinical GTR are unique, and concludes by examining whether the RAC's oversight is a useful model that should be reproduced for other similar areas of clinical research.Clinical GTR is governed by the same (...)
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  45.  46
    On the supposed dilemma of conciliationism.Stefan Reining - 2016 - Episteme 13 (3):305-328.
    My aim in this paper is to propose a way to resolve a supposed dilemma currently troubling the debate about rational belief formation in cases of peer disagreement. In section 1, I will introduce the general debate in question as well as the kind of view figuring in the supposed dilemma. In section 2, I will describe how the supposed dilemma arises. In section 3, I will consider the replies that have hitherto been offered and explain in how far these (...)
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  46.  99
    Appearances and Things in Themselves: Actuality and Identity.Nicholas F. Stang - 2016 - Kantian Review 21 (2):283-292.
    Lucy Allais’s anti-phenomenalist interpretation of transcendental idealism is incomplete in two ways. First of all, like some phenomenalists, she is committed to denying the coherence of claims of numerical identity of appearances and things in themselves. Secondly, she fails to explain adequately what grounds the actuality of appearances. This opens the door to a phenomenalist understanding of appearances. View HTML Send article to KindleTo send this article to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail (...)
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  47. The real presence.H. E. Baber - 2013 - Religious Studies 49 (1):19-33.
    The doctrine that Christ is really present in the Eucharist appears to entail that Christ's body is not only multiply located but present in different ways at different locations. Moreover, the doctrine poses an even more difficult meta-question: what makes a theological explanation of the Eucharist a ‘real presence’ account? Aquinas's defence of transubstantiation, perhaps the paradigmatic account, invokes Aristotelian metaphysics and the machinery of Scholastic philosophy. My aim is not to produce a ‘rational reconstruction’ of his analysis but rather (...)
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  48.  44
    Where the Right Gets in: On Rawls’s Criticism of Habermas’s Conception of Legitimacy.James Gordon Finlayson - 2016 - Kantian Review 21 (2):161-183.
    Many commentators have failed to identify the important issues at the heart of the debate between Habermas and Rawls. This is partly because they give undue attention to differences between Rawls’s original position and Habermas’s principle, neither of which is germane to the actual dispute. The dispute is at bottom about how best to conceive of democratic legitimacy. Rawls indicates where the dividing issues lie when he objects that Habermas’s account of democratic legitimacy is comprehensive and his is confined to (...)
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    How can yes-or-no questions be informative before they are answered?Emmanuel J. Genot & Justine Jacot - 2012 - Episteme 9 (2):189-204.
    We examine a special case of inquiry games and give an account of the informational import of asking questions. We focus on yes-or-no questions, which always carry information about the questioner's strategy, but never about the state of Nature, and show how strategic information reduces uncertainty through inferences about other players' goals and strategies. This uncertainty cannot always be captured by information structures of classical game theory. We conclude by discussing the connection with Gricean pragmatics and contextual constraints on interpretation.Send (...)
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  50.  9
    Understanding nurses’ justification of restraint in a neurosurgical setting: A qualitative interview study.Amina Guenna Holmgren, Ann-Christin von Vogelsang, Anna Lindblad & Niklas Juth - 2023 - Nursing Ethics 30 (1):71-85.
    Background Despite its negative impact on patients and nurses, the use of restraint in somatic health care continues in many settings. Understanding the reasons and justifications for the use of restraint among nurses is crucial in order to manage this challenge. Aim To understand nurses’ justifications for restraint use in neurosurgical care. Research design A qualitative, descriptive design was used. Data were analysed with inductive qualitative content analysis. Participants and research context Semi-structured interviews with 15 nurses working in three neurosurgical (...)
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