Introduction Future HIV vaccine efficacy trials with adolescents will need to ensure that participants comprehend study concepts in order to confer true informed assent. A Hepatitis B vaccine trial with adolescents offers valuable opportunity to test youth understanding of vaccine trial requirements in general. Methods Youth reviewed a simplified assent form with study investigators and then completed a comprehension questionnaire. Once enrolled, all youth were tested for HIV and confirmed to be HIV-negative. Results 123 youth completed the questionnaire (mean age=15 (...) years; 63% male; 70% Hispanic). Overall, only 69 (56%) youth answered all six questions correctly. Conclusions Youth enrolled in a Hepatitis B vaccine trial demonstrated variable comprehension of the study design and various methodological concepts, such as treatment group masking. (shrink)

Biologists study life in its various physical forms, while philosophers of biology seek answers to questions about the nature, purpose, and impact of this research. What permits us to distinguish between living and nonliving things even though both are made of the same minerals? Is the complex structure of organisms proof that a creative force is working its will in the physical universe, or are existing life-forms the random result of an evolutionary process working itself out over eons of time? (...) What moral and social questions arise regarding modern advances in biotechnology? What is more relevant to human nature: genetics or sociocultural influences? Is Darwinism the death-knell of God? These are just some of the vital questions addressed by a distinguished group of philosophers and scientists which includes: Aristotle, Francisco J. Ayala, , Michael Benton, Tom Bethell, Joe Cain, David Castle, Charles Darwin, Richard Dawkins, Michael Denton, A.G.N. Flew, Stephen Jay Gould, J.B.S. Haldane, John F. Haught, D. W. E. Hone, James W. Kirchner, James Lovelock, Jane Maienschein, Ernst Mayr, Gregory M. Mikkelson, Leslie Orgal, William Paley, the Prince of Wales, Christopher Pynes, Richard A. Richards, Mark Ridley, Holmes Rolston III, Michael Ruse, Lee Silver, Elliott Sober, Kim Sterelny, Derek Turner, and Edward O. Wilson. This second edition contains material on design without selection, testing macroevolutionary claims, recent biotechnological issues, key ecological concerns, the Gaia hypothesis, genetically modified foods, and the so-called intelligent design movement. (shrink)

The tomb of the ancient Pharaoh, Tut-ankh-Amen, was opened some years ago. Lord Carnarvon, who financed the investigations, died shortly after the opening. Lord Westbury fell to his death from the high window of a London flat on February 21, 1930. His son, the Hon. Richard Bethell, had been found dead in his room the previous November. He was secretary to Mr. Howard Carter, one discoverer of Tut-ankh-Amen’s tomb. Many persons who had been connected with the excavations had died previously—M. (...) Benedite, for example, died after participating in the research, and Mrs. Greely committed suicide after visiting the tomb. The Hon. Richard Bethell was the thirteenth person connected with Tut-ankh-Amen's tomb, directly or indirectly, to die, and his father, Lord Westbury, was the fourteenth. The death of Lord Carnarvon, a few weeks after the tomb was opened, stirred the notion that a curse had been placed on the mummy of the Pharaoh, or in his tomb, to menace violators. Succeeding deaths kept the notion alive, and the thirteenth death, of the Hon. Richard Bethell, wrung an opinion from Dr. Mardus, the eminent French Egyptologist. He was convinced that the ancient Egyptians could surround “their mummies with some dynamic force.” Such a force lurked in the tomb of Tut-ankh-Amen. Its nature was unknown, but it had manifested itself in the series of deaths. (shrink)

Attempts have been made to prove God's non-existence. Often this takes the form of an appeal to the so-called Argument from Evil: if God were to exist, then he would not permit as much suffering in the world as there actually is. Hence the fact that there is so much suffering constitutes evidence for God's non-existence. In this essay I propose a variation which I shall call ‘The Argument from Non-belief’. Its basic idea is that if God were to exist, (...) then he would not permit as much non-belief in the world as there actually is. Hence the fact that there is so much non-belief constitutes evidence for God's non-existence. (shrink)

Le XI.ème Congrès International de Philosophie Médiévale de la Société Internationale pour l’Étude de la Philosophie Médiévale (S.I.E.P.M..) s’est déroulé à Porto (Portugal), du 26 au 30 août 2002, sous le thème général: Intellect et Imagination dans la Philosophie Médiévale. A partir des héritages platonicien, aristotélicien, stoïcien, ou néo-platonicien (dans leurs variantes grecques, latines, arabes, juives), la conceptualisation et la problématisation de l’imagination et de l’intellect, ou même des facultés de l’âme en général, apparaissaient comme une ouverture possible pour aborder (...) les principaux points de la pensée médiévale. Les Actes du congrès montrent que « imagination » et « intellect » sont porteurs d’une richesse philosophique extraordinaire dans l’économie de la philosophie médiévale et de la constitution de ses spécificités historiques. Dans sa signification la plus large, la théorisation de ces deux facultés de l’âme permet de dédoubler le débat en au moins six grands domaines: — la relation avec le sensible, où la fantaisie/l’imagination joue le rôle de médiation dans la perception du monde et dans la constitution de la connaissance ; — la réflexion sur l’acte de connaître et la découverte de soi en tant que sujet de pensée ; — la position dans la nature, dans le cosmos, et dans le temps de celui qui pense et qui connaît par les sens externes, internes et par l’intellect ; — la recherche d’un fondement pour la connaissance et l’action, par la possibilité du dépassement de la distante proximité du transcendant, de l’absolu, de la vérité et du bien ; — la réalisation de la félicité en tant qu’objectif ultime, de même que la découverte d’une tendance au dépassement actif ou mystique de toutes les limites naturelles et des facultés de l’âme ; — la constitution de théories de l’image, sensible ou intellectuelle, et de ses fonctions. Les 3 volumes d’Actes incluent les 16 leçons plénières et 112 communications, ainsi que les index correspondants (manuscrits ; noms anciens et médiévaux ; noms modernes ; auteurs). Le volume IV des Actes, contenant 39 communications et des index, est publié par la revue " Mediaevalia. Textos e Estudos ", du Gabinete de Filosofia Medieval de l’Universidade do Porto (volume 23, de 2004). Ouvrage publié avec l’appui de l’Universidade do Porto, de la Faculdade de Letras da U.P., du Departamento de Filosofia - F.L.U.P. et de la Fundação para a Ciência e a Tecnologia (Portugal). (shrink)

In this volume, fourteen scholars, many of them contemporaries of Professor Frank, engage with his legacy with important and seminal works which take some of ...

A timeless resource that probes Jewish texts, spirituality, and observance provides a unique approach to caring for the aging and elderly, helping today's ...

Richard M Weaver, a thinker and writer celebrated for his unsparing diagnoses and realistic remedies for the ills of our age, is known largely through a few of his works that remain in print. This new collection of Weaver's shorter writings, assembled by Ted J Smith III, Weaver's leading biographer, presents many long-out-of-print and never-before-published works that give new range and depth to Weaver's sweeping thought. Included are eleven previously unpublished essays and speeches that were left in near-final form at (...) the time of Weaver's death in 1963. In all, there are some one hundred and twenty-six essays, speeches, book reviews, and editorials. (shrink)

Over the course of an illustrious career, the late Bernard Diamond established himself as the preeminent forensic psychiatrist of the century. _The Psychiatrist in the Courtroom_ brings together in a single volume Diamond's pivotal contributions to a variety of important issues, including the nature of diminished capacity, the fallacy of the impartial expert, the predictability of dangerousness, and the unacceptability of hypnotically facilitated memory in courtroom proceedings. Ably introduced and edited by Jacques M. Quen, M.D., a close colleague of Diamond's (...) and leading historian of forensic psychiatry, these writings enable experts and neophytes alike to track Diamond's evolving positions while clarifying where current legal and psychiatric opinion converge -- and diverge -- on a host of critical topics. For the forensic specialist, _The Psychiatrist in the Courtroom_ is not only an invaluable reference work but a compassionate reminder of the clinician's obligation to protect patients in legal proceedings. And in an age when clinicians are increasingly called into court, the book will be no less valuable to psychoanalysts and other mental health professionals eager for an introduction to the intricacies of judicial reasoning. Then, too, owing to Diamond's clinical acumen, the book is a compelling human document. With great erudition and deep compassion, Diamond tackles these and other knotty questions, always with an eye to clarifying the legal and clinical implications of the answers. By combining superb clinical gifts with an incisive understanding of legal principle, Diamond produced a seminal corpus whose relevance to discussions of therapeutic ethics and to legal debates will continue well into the next century. (shrink)

First published in 1986. Nations have a unity often described as 'cultural'; and within them there are divergences some of which are termed 'political'. But culture and politics do not, therefore, comprise two wholly distinct zones or orders of experience, the one marked by unity, the other by plurality. Unity and plurality interpenetrate. These insights, which derive from the thinking of Herder, have been fundamental to the work of F. M. Barnard. In this volume a number of scholars contribute, in (...) Barnardian vein, reflections on the tensions between unity and plurality in the history of ideas. The central underlying question is, in essence, 'what is the context of political life?' The question remains of more importance than any single answer. (shrink)

Using as a springboard a three-way debate between theoretical physicist Lee Smolin, philosopher of science Nancy Cartwright and myself, I address in layman’s terms the issues of why we need a unified theory of the fundamental interactions and why, in my opinion, string and M-theory currently offer the best hope. The focus will be on responding more generally to the various criticisms. I also describe the diverse application of string/M-theory techniques to other branches of physics and mathematics which render the (...) whole enterprise worthwhile whether or not “a theory of everything” is forthcoming. (shrink)

SummarySeventeenth-century thinking on the relationship between trade and state power was routinely conducted using the concept of state interests, which enabled users to conceive a Europe of competing states that managed the balance of power through trade and war. Poor interest management could arise from ignorance, error, or the divergence between the private interests of rulers and a state's true interests. The stakes of pursuing or neglecting true interest were high: the survival and prosperity of the state. The dominance of (...) ‘mercantilism’ as a historiographical category has obscured the role of interest in early modern thought. This paper examines the work of one of England's most prolific interest writers, Slingsby Bethel, to demonstrate the importance of reading interest writings without recourse to mercantilism. The two focuses are, first, how the rhetoric of counsel was used to defend an ordinary subject's presumption to comment on state affairs and, second, the capacity for interest writers to construe the rise and fall of state power in terms of good laws and statesmanship. (shrink)

In fall 1844, a party of colonists led by William Keil arrived at what was to become their new home, a gentle slope rising from the bank of the North River in Shelby County, Missouri, about forty-five miles west of Hannibal. One year later the utopian Bethel Colony had been laid out, houses were being added as fast as they could be built, and construction of a steam-powered gristmill was under way.The Bethel colonists were Bible Communists who found (...) the inspiration for their communal life in the book of Acts, which records that in the Early Church "as many as were possessors of lands or houses sold them and brought the proceeds and laid them at the apostles' feet; and distribution was made to each as any had need"... (shrink)

Twentieth century philosophers introduced the distinction between “objective rightness” and “subjective rightness” to achieve two primary goals. The first goal is to reduce the paradoxical tension between our judgments of what is best for an agent to do in light of the actual circumstances in which she acts and what is wisest for her to do in light of her mistaken or uncertain beliefs about her circumstances. The second goal is to provide moral guidance to an agent who may be (...) uncertain about the circumstances in which she acts, and hence is unable to use her standard moral principle directly in deciding what to do. This paper distinguishes two important senses of “moral guidance”; proposes criteria of adequacy for accounts of subjective rightness; canvasses existing definitions for “subjective rightness”; finds them all deficient; and proposes a new and more successful account. It argues that each comprehensive moral theory must include multiple principles of subjective rightness to address the epistemic situations of the full range of moral decision-makers, and shows that accounts of subjective rightness formulated in terms of what it would reasonable for the agent to believe cannot provide that guidance. (shrink)

Taylor, R. A tribute.--Epistemology: Cornman, J. W. Chisholm on sensing and perceiving. Ross, J. F. Testimonial evidence. Lehrer, K. Reason and consistency. Keim, R. Epistemic values and epistemic viewpoints. Hanen, M. Confirmation, explanation, and acceptance. Canfield, J. V. "I know that I am in pain" is senseless. Steel, T. J. Knowledge and the self-presenting.--Metaphysics: Cartwright, R. Scattered objects. Duggan, T. J. Hume on causation. Arnaud, R. B. Brentanist relations. Johnson, M. L., Jr. Events as recurrables.--Ethics: Stevenson, J. T. On doxastic (...) responsibility. Feldman, F. World utilitarianism. Lamb, J. W. Some definitions for the theory of rules. Donnelly, J. Suicide: some epistemological considerations. (shrink)

Listening to someone from some distance in a crowded room you may experience the following phenomenon: when looking at them speak, you may both hear and see where the source of the sounds is; but when your eyes are turned elsewhere, you may no longer be able to detect exactly where the voice must be coming from. With your eyes again fixed on the speaker, and the movement of her lips a clear sense of the source of the sound will (...) return. This ‘ventriloquist’ effect reflects the ways in which visual cognition can dominate auditory perception. And this phenomenological observation is one what you can verify or disconfirm in your own case just by the slightest reflection on what it is like for you to listen to someone with or without visual contact with them. (shrink)

Originally published in 1988, M. C. Dillon's classic study of Merleau-Ponty is now available in a revised second edition containing a new preface and a new ...

W.M. Gorman has been a major figure in the development of economies during the past forty years. His publications on separability, aggregation, duality and the modelling of consumer demand are recognized as fundamental contributions to economic theory. Many of his unpublished papers have achieved similar status as privately-circulated classics.This volume brings together for the first time all Gorman's important work, much of which has never been published before, on aggregation across commodities and agents, including separability, budgeting, representative agents, and the (...) construction of capital and labour aggregates. Each chapter is preceded by an editorial introduction which describes its origin and place within the literature as well as the main results themselves. A forthcoming second volume, Modelling and Methodology, will cover topics on duality, demand, trade, and welfare.This book will appeal to academic economists interested in either specific aspects of Gorman's work or in the evolution of economic theory. (shrink)

We argue that thoughts are structures of concepts, and that concepts should be individuated by their origins, rather than in terms of their semantic or epistemic properties. Many features of cognition turn on the vehicles of content, thoughts, rather than on the nature of the contents they express. Originalism makes concepts available to explain, with no threat of circularity, puzzling cases concerning thought. In this paper, we mention Hesperus/Phosphorus puzzles, the Evans-Perry example of the ship seen through different windows, and (...) Mates cases, and we believe that there are many additional applications. (shrink)

A large body of literature agrees that persons with schizophrenia suffer from a Theory of Mind deficit. However, most empirical studies have focused on third-person, egocentric ToM, underestimating other facets of this complex cognitive skill. Aim of this research is to examine the ToM of schizophrenic persons considering its various aspects, to determine whether some components are more impaired than others. We developed a Theory of Mind Assessment Scale and administered it to 22 persons with a DSM-IV diagnosis of schizophrenia (...) and a matching control group. Th.o.m.a.s. is a semi-structured interview which allows a multi-component measurement of ToM. Both groups were also administered a few existing ToM tasks and the schizophrenic subjects were administered the Positive and Negative Symptoms Scale and the WAIS-R. The schizophrenic persons performed worse than control at all the ToM measurements; however, these deficits appeared to be differently distributed among different components of ToM. Our conclusion is that ToM deficits are not unitary in schizophrenia, which also testifies to the importance of a complete and articulated investigation of ToM. (shrink)

Western democracy is now at a critical juncture. Some worry that power has been wrested from the people and placed in the hands of a small political elite. Others argue that the democratic system gives too much power to a populace that is largely ill-informed and easily swayed by demagogues. This classic study of democratic principles is thus now more relevant than ever. A renowned historian of antiquity and political philosophy, Sir M.I. Finley offers a comparative analysis of Greek and (...) modern conceptions of democracy. As he puts the ancient Greeks in dialogue with their contemporary counterparts, Finley tackles some of the most pressing issues of our day, including public apathy, partisanship, consensus politics, distrust of professional politicians, and the limits of free speech. Including three lectures that Finley delivered at Rutgers University, plus two additional essays that further illuminate his thinking, _Democracy Ancient and Modern _explores the dramatic differences between the close-knit civil society of the ancient Greeks and our own atomized mass societies. By mapping out democracy’s past and its present manifestations, this book helps us plot a course for democracy’s future. (shrink)