Male sexual arousal (SA) has been known as a multidimensional experience involving closely interrelated and coordinated neurobehavioral components that rely on widespread brain regions. Recent functional neuroimaging studies have shown relation between abnormal/altered dynamics in these circuits and male sexual dysfunction. However, alterations in the topological1 organization of structural brain networks in male sexual dysfunction are still unclear. Here, we used graph theory2 to investigate the topological properties of large-scale structural brain networks, which were constructed using inter-regional correlations of cortical (...) thickness between 78 cortical regions (subcortical regions were not included due to the used cortical surface model) in 40 patients with psychogenic erectile dysfunction (pED) and 39 normal controls. Compared with normal controls, pED patients exhibited a less optimal global topological organization with reduced global and increased local efficiencies. Our results suggest disrupted neural integration among distant brain regions in pED patients, consistent with previous reports of impaired white matter structure and abnormal functional integrity in pED. Additionally, disrupted global network topology in pED was observed to be primarily relevant to altered subnetwork and nodal properties within the networks mediating the cognitive, motivational and inhibitory processes of male SA, possibly indicating disrupted integration of these networks in the whole brain networks and might account for pED patients’ abnormal cognitive, motivational and inhibitory processes for male SA. In total, our findings provide evidence for disrupted integrity in large-scale brain networks underlying the neurobehavioral processes of male SA in pED and provide new insights into the understanding of the pathophysiological mechanisms of pED. (shrink)

The user data mining was introduced into the model construction process, and the user behavior was decomposed by analyzing various influencing factors through the factorization machine learning method. In the recommendation screening stage, the collaborative filtering recommendation is combined to screen the recommendation candidate set. The idea of user-based collaborative filtering is used for reference to obtain music works favored by similar users. On the other hand, we learn from item-based CF, which ensures that the candidate set covers user preference. (...) Firstly, the user’s interest value is predicted by using dynamic interest model. Then, the common problems such as cold start and hot items processing are fully considered. The frequent pattern growth algorithm is compared with the association rule algorithm based on the collaborative filtering recommendation algorithm and the content-based recommendation algorithm, which proves the superiority of the algorithm and its role in solving the recommendation problem after applying the recommendation. The music data in the database data conversion effectively improve the efficiency and accuracy of mining. According to the implementation of the algorithm described in this article, the accuracy of the music recommendation results used to recommend user satisfaction is proved. And the recommended music is indeed feasible and practical. (shrink)

This study explores the research paradigms of contemporary business ethics research in 2001–2008. With citation data from the top two business ethics journals included in the Social Sciences Citation Index, this study conducts citation and co-citation analysis to identify the most important publications, scholars, and research themes in the business ethics area and then maps the intellectual structure of business ethics studies between 2001 and 2008. The results show that current business ethics studies cluster around four major research themes, including (...) morality and social contract theory, ethical decision making, corporate social responsibility, and stakeholder theory. This study helps profile the invisible network of knowledge production in business ethics and provides important insights on current research paradigms of business ethics studies. (shrink)

This study explores the research paradigms of contemporary business ethics research in 2001–2008. With citation data from the top two business ethics journals included in the Social Sciences Citation Index, this study conducts citation and co‐citation analysis to identify the most important publications, scholars, and research themes in the business ethics area and then maps the intellectual structure of business ethics studies between 2001 and 2008. The results show that current business ethics studies cluster around four major research themes, including (...) morality and social contract theory, ethical decision making, corporate social responsibility, and stakeholder theory. This study helps profile the invisible network of knowledge production in business ethics and provides important insights on current research paradigms of business ethics studies. (shrink)

While N6‐methyladenosine (m6A) is a well‐known epigenetic modification in bacterial DNA, it remained largely unstudied in eukaryotes. Recent studies have brought to fore its potential epigenetic role across diverse eukaryotes with biological consequences, which are distinct and possibly even opposite to the well‐studied 5‐methylcytosine mark. Adenine methyltransferases appear to have been independently acquired by eukaryotes on at least 13 occasions from prokaryotic restriction‐modification and counter‐restriction systems. On at least four to five instances, these methyltransferases were recruited as RNA methylases. Thus, (...) m6A marks in eukaryotic DNA and RNA might be more widespread and diversified than previously believed. Several m6A‐binding protein domains from prokaryotes were also acquired by eukaryotes, facilitating prediction of potential readers for these marks. Further, multiple lineages of the AlkB family of dioxygenases have been recruited as m6A demethylases. Although members of the TET/JBP family of dioxygenases have also been suggested to be m6A demethylases, this proposal needs more careful evaluation. (shrink)

胡適（1891-1962），安徽績溪人。原名嗣穈，後改名胡適，字適之，曾用筆名希彊、臧暉等。新文化運動的奠基人與領袖之一，倡導約翰・杜威的實用主義。1917年回國任教北大，參與編輯《新青年》《努力周報 》《獨立評論》等雜誌，先後擔任中華民國駐美大使、國立北京大學校長、台北「中央研究院」院長等職，著有《中國哲學史大綱》《嘗試集》《胡適文存》等書，並獲諾貝爾文學獎提名。.

This paper proposes an adaptive neural network control approach for a direct-current system with full state constraints. To guarantee that state constraints always remain in the asymmetric time-varying constraint regions, the asymmetric time-varying Barrier Lyapunov Function is employed to structure an adaptive NN controller. As we all know that the constant constraint is only a special case of the time-varying constraint, hence, the proposed control method is more general for dealing with constraint problem as compared with the existing works on (...) DC systems. As far as we know, this system is the first studied situations with time-varying constraints. Using Lyapunov analysis, all signals in the closed-loop system are proved to be bounded and the constraints are not violated. In this paper, the effectiveness of the control method is demonstrated by simulation results. (shrink)

本书分为神话与诉讼,历史与诉讼,故事与诉讼,制度法理,学术争鸣,法学教育,治学人生等八辑,收录了剧与诉的随想,正义之舞,游戏与诉讼,圣殿骑士的死亡密码,走向刑事宪法,法官权力之源与品格之治,法国法学教 育三题,关问于山水之间等文章.

Finding meaning in our lives is a central tenet to the human experience and a core contributor to mental health. Individuals tend to actively seek the sources of meaning in their lives or consciously enact efforts to create or “craft” meaning in different life domains. These overall “Life Crafting” behaviors refer to the conscious efforts individuals exert to create meaning in their lives through cognitively framing how they view life, seeking social support systems to manage life challenges, and actively seeking (...) challenges to facilitate personal growth. Specifically, these behaviors are actioned to better align life goals, personal needs, values, and capabilities. However, no psychological assessment instrument currently exists to measure overall life crafting. As such, the purpose of this paper was twofold: to conceptualize life crafting and to develop, validate and evaluate a robust measure of overall life crafting. A mixed-method, multi-study research design was employed. First, nine participants were interviewed to determine the methods or techniques used to craft meaningful life experiences. These methods/techniques were used as indicators to create an initial item pool which was then reviewed by a panel of experts to ensure face validity. Second, in Study 1, the factorial structure of the instrument was explored by gathering data from a convenience sample, with the results showing support for a three-factor structure of life crafting, consisting of cognitive crafting, seeking social support, and seeking challenges. Finally, in Study 2, the aim was to confirm the factorial structure of the Life Crafting scale and to determine its level of internal consistency, partial measurement invariance across genders, and criterion validity [meaning in life, mental health, work engagement, and job burnout ]. The results supported a second-order factorial model of Life Crafting, which comprised of three first-order factors. Therefore, the Life Crafting Scale can be used as a valid and reliable instrument to measure- and track the effectiveness of life crafting interventions. (shrink)

This article explores how experienced regret and relief evoked in a risky gambling task influence subsequent intertemporal pro-social behavior. We apply a dictator game experiment with delayed rewards to investigate the effect on donating behavior by simultaneously the time delay when the recipient accepts the donation and the emotions experienced by the participant. We examine this effect using a choice titration procedure. The results reveal that independent of the prior experienced emotions, participants’ donations decrease as the time delay rises; the (...) hyperbolic model provides a better explanation of this finding. Significantly, experienced regret impacts the shape of the social discount function with delayed rewards, which is reflected in notably different discount rates. Participants who experienced regret exhibit a lower discount rate than those in the relief condition. Note that this distinct type of generosity differs significantly at the 14-day delay but not at the shortest and longest. It follows that regret can promote future altruism and intertemporal pro-social behavior, depending on the delay. (shrink)

This paper introduces the Generalized Argumentation Theory which takes argumentation as a locally rational socio-cultural interaction governed by social norms and carried out through discourse between the members of a socio-cultural community in order to reason things out. Then we bring in the basic structure of generalized argumentation and the localized procedure of Generalized Argumentation Theory for studying the argumentative rules. On the basis of above introduction, we use the localized procedure to analyze a case of political argumentation by reciting (...) poems in ancient China. By doing so, it’s indicated that political argumentation by reciting poems, in essence, takes cultural principle of Li of the Spring and Autumn Period as argumentative rules and uses poems to express ideas, in virtue of which arguments are accepted as locally rational by the politicians at that time. At last, the Little Red Book quotation fight, a similar political activity, is discussed briefly to show the significance that ancient Chinese political argumentation has on contemporary argumentation. (shrink)

In this article, we offer a critical realist conception of curriculum that aims to cultivate critical thinking (CT) and liberate students from egocentric rationality. We first examine egocentric rationality as a problem emerging from the technicist paradigm of cultivating CT in higher education, exemplified by issues arising from the pedagogical activity of debate. We then examine existing approaches to cultivating CT, focusing on the extent to which their goals and conceptions of CT could liberate students from egocentric rationality. Drawing on (...) Roy Bhaskar’s stratified conception of being and principle of immanent critique, we offer a critical realist conception of curriculum, explaining its definition of CT as the capacity for self-critique. We shall illustrate, in the context of an undergraduate debate course, how such capacity can be developed in order to liberate students from egocentric rationality. Curriculum is thus a critical praxis, a created space where student’s CT develops in a way that is intrinsically entwined with their being and becoming. This article extends the philosophical basis for integrating CT with curriculum and offers pedagogical implications. (shrink)

Euthanasia in China is gaining increasing acceptance among physicians, intellectuals, and even the people. This paper surveys current attitudes towards euthanasia and suggests why it should be legalized. Keywords: euthanasia, euthanasia in China CiteULike Connotea Del.icio.us What's this?

In an effort to fulfill the commands of Chairman Mao and Premier Zhou, our people are working strenuously to build our country into a powerful, modernized socialist state before the end of the century. Following the gradual progress of the four modernizations, the productive forces will rapidly grow, and the socialization level of production is bound to rise noticeably. How to understand the socialization of production, how to promptly readjust the relations of production and the superstructure in order to fit (...) in with the new situation in which the socialization level of production is continuously on the rise, and how to reform the management of industrial and agricultural enterprises as well as the administrative system of the national economy in order to quicken the speed of economic development pose a new problem calling for earnest study and exploration. (shrink)

bakhsh-i 1. Muqaddamah, Manṭiq, Umūr-i ʻāmmah, Ṭabīʻyāt, Ilāhīyāt.

This chapter narrates the author's fascination with the intriguing and elusive face and image of Hannah Arendt—as well as her life story. Experience and world events transformed her inner and outer appearance, etching her life story on her face. Her life story was that of an intellectual Jewish woman who experienced the European turmoil of the 20th century and tried to understand the sources of human evil and violence. The author traced her portrait from a very young woman to her (...) old age. The source materials included unfamiliar photos of Arendt at different stages of her life. (shrink)

베이컨은 타당한 철학 방법론으로 귀납법만을 인정한 경험론자로 평가받는다. 그런 평가는 귀납법이 학문의 정초를 위한 방법으로는 매우 불충분하다는 인식과 더불어 그의 철학 방법론이 근대철학의 형성에 공헌하지 못했다는 평가로 이어진다. 본 논문은 그의 귀납법에 대한 비판이 정당한가를 세밀히 검토해서, 그의 귀납법 내에 부재한다고 비판받는 점들이 오히려 그의 귀납법을 구성하는 핵심 특징임을 밝히려 한다. 그리고 지금까지 베이컨 철학 방법론의 현대적 의의를 드러내려 했던 연구자들조차 그의 귀납법 본질을 밝혀내지 못했는데, 그 주원인은 그들이 상호 모순되는 것처럼 보이는 그의 귀납법 특징들의 연관성 규명에 실패했기 때문이다. 본 (...) 논문은 그것을 밝혀줄 열쇠는 그의 우상론 재해석에 있음과 또한 다양한 그의 귀납법 특징들이 어떤 맥락에서 이해되어야만 하는가를 밝히려 한다. 마지막으로 그의 귀납법이 근대자연과학혁명에서 획기적 공헌을 했으며, 이미 지나간 과거의 철학사적 문제가 아니라, 모든 자연 탐구자들이 반드시 명심해야만 할 중요한 교훈을 주고 있음을 보여주려 한다. (shrink)

This series publishes outstanding monographs and edited volumes that investigate all aspects of Kant's philosophy, including its systematic relationship to other philosophical approaches, both past and present. Studies that appear in the series are distinguished by their innovative nature and ability to close lacunae in the research. In this way, the series is a venue for the latest findings in scholarship on Kant.