From dogs to gods, the science of understanding mysterious minds--including your own. Nothing seems more real than the minds of other people. When you consider what your boss is thinking or whether your spouse is happy, you are admitting them into the "mind club." It's easy to assume other humans can think and feel, but what about a cow, a computer, a corporation? What kinds of mind do they have? Daniel M. Wegner and Kurt Gray are award-winning psychologists who (...) have discovered that minds--while incredibly important--are a matter of perception. Their research opens a trove of new findings, with insights into human behavior that are fascinating, frightening and funny. The Mind Club explains why we love some animals and eat others, why people debate the existence of God so intensely, how good people can be so cruel, and why robots make such poor lovers. By investigating the mind perception of extraordinary targets--animals, machines, comatose people, god--Wegner and Gray explain what it means to have a mind, and why it matters so much. Fusing cutting-edge research and personal anecdotes, The Mind Club explores the moral dimensions of mind perception with wit and compassion, revealing the surprisingly simple basis for what compels us to love and hate, to harm and to protect. (shrink)

When someone steps on your toe on purpose, it seems to hurt more than when the person does the same thing unintentionally. The physical parameters of the harm may not differ—your toe is flattened in both cases—but the psychological experience of pain is changed nonetheless. Intentional harms are premeditated by another person and have the specific purpose of causing pain. In a sense, intended harms are events initiated by one mind to communicate meaning (malice) to another, and this could shape (...) the recipient’s experience. This study examined whether self-reported pain is indeed higher when the events producing the pain are understood as intentionally (as opposed to unintentionally) caused by another person. Although pain was traditionally conceived to be solely physical in nature (Aydede, 2005), its experience varies substantially with psychological context. The placebo analgesia effect, for example, is the reduction of pain without a change in physical stimulation when context, expectations, or sugar pills challenge the interpretation of a sensation as painful (e.g., Fields, 2008). The nocebo effect, in turn, is the experience of pain without any physical stimulation—as when participants report headaches when told that a (nonexistent) electric current is passing through their heads (Schweiger & Parducci, 1981). These variations in pain experience seem to depend on the meaning of the stimulus: A sugar pill is meant to decrease pain, whereas electric current is meant to increase pain. In an interpersonal context, the meaning of an action is derived from the would complete. perceiver’s perceptions of the actor’s intention (Clark, 1996). (shrink)

Believing in God requires not only a leap of faith but also an extension of people’s normal capacity to perceive the minds of others. Usually, people perceive minds of all kinds by trying to understand their conscious experience (what it is like to be them) and their agency (what they can do). Although humans are perceived to have both agency and experience, humans appear to see God as possessing agency, but not experience. God’s unique mind is due, the authors suggest, (...) to the uniquely moral role He occupies. In this article, the authors propose that God is seen as the ultimate moral agent, the entity people blame and praise when they receive anomalous harm and help. Support for this proposition comes from research on mind perception, morality, and moral typecasting. Interestingly, although people perceive God as the author of salvation, suffering seems to evoke even more attributions to the divine. (shrink)

Although torture can establish guilt through confession, how are judgments of guilt made when tortured suspects do not confess? We suggest that perceived guilt is based inappropriately upon how much pain suspects appear to suffer during torture. Two psychological theories provide competing predictions about the link between pain and perceived blame: cognitive dissonance, which links pain to blame, and moral typecasting, which links pain to innocence. We hypothesized that dissonance might characterize the relationship between torture and blame for those close (...) to the torture, while moral typecasting might characterize this relationship for those more distant from it. Accordingly, this experiment placed participants into one of two different roles in which people may be exposed to torture. Participants in the proximal role of prison staffer saw suffering torture victims as relatively more guilty, while participants in the relatively distant role of a radio listener saw suffering victims as more innocent. (shrink)

Anger, disgust, elevation, sympathy, relief. If the subjective experience of each of these emotions is the same whether elicited by moral or nonmoral events, then what makes moral emotions unique? We suggest that the configuration of moral emotions is special—a configuration given by the underlying structure of morality. Research suggests that people divide the moral world along the two dimensions of valence (help/harm) and moral type (agent/patient). The intersection of these two dimensions gives four moral exemplars—heroes, villains, victims and beneficiaries—each (...) of which elicits unique emotions. For example, victims (harm/patient) elicit sympathy and sadness. Dividing moral emotions into these four quadrants provides predictions about which emotions reinforce, oppose and complement each other. (shrink)

Participants compared the mental capacities of various human and nonhuman characters via online surveys. Factor analysis revealed two dimensions of mind perception, Experience and Agency. The dimensions predicted different moral judgments but were both related to valuing of mind.

The uncanny valley—the unnerving nature of humanlike robots—is an intriguing idea, but both its existence and its underlying cause are debated. We propose that humanlike robots are not only unnerving, but are so because their appearance prompts attributions of mind. In particular, we suggest that machines become unnerving when people ascribe to them experience, rather than agency. Experiment 1 examined whether a machine’s humanlike appearance prompts both ascriptions of experience and feelings of unease. Experiment 2 tested whether a machine capable (...) of experience remains unnerving, even without a humanlike appearance. Experiment 3 investigated whether the perceived lack of experience can also help explain the creepiness of unfeeling humans and philosophical zombies. These experiments demonstrate that feelings of uncanniness are tied to perceptions of experience, and also suggest that experience—but not agency—is seen as fundamental to humans, and fundamentally lacking in machines. (shrink)

PurposeThe purported benefits and risks of immediately sequential bilateral cataract surgery have been well described, yet the procedure remains controversial among UK ophthalmologists. As many of the controversies of ISBCS are underpinned by ethical dilemmas, the aim of this work was to explore the ethical perspectives of ISBCS from a variety of stakeholder viewpoints.MethodA semi-structured independent stakeholder meeting was convened at the Royal College of Ophthalmologists London headquarters in June 2018. In total, 29 stakeholders attended the meeting. The professional characteristics (...) of stakeholders included but were not limited to: ophthalmologists, patients, religious leaders, ethicists, lawyers and commissioners. Thematic qualitative analysis using methodology proposed by Braun and Clarke was conducted on the resultant transcript of the discussion.ResultsThemes identified include: beneficence and non-maleficence ; autonomy ; distributive justice.ConclusionThis analysis provides a reference point for the ethical factors surrounding ISBCS. The stakeholders concluded that this approach was an ethical undertaking provided patient autonomy was appropriately attained. This requires a patient’s interpretation of the risk-benefit balance, which must include an understanding of the low but unquantifiable risk of severe complications. A surgeon must aim to minimise risks through the adaption of accepted surgical protocols and by performing appropriate patient selection. Currently, cost savings to healthcare that may occur following the implementation of ISBCS should be considered a secondary benefit of the protocol. (shrink)

PurposeThe purported benefits and risks of immediately sequential bilateral cataract surgery have been well described, yet the procedure remains controversial among UK ophthalmologists. As many of the controversies of ISBCS are underpinned by ethical dilemmas, the aim of this work was to explore the ethical perspectives of ISBCS from a variety of stakeholder viewpoints.MethodA semi-structured independent stakeholder meeting was convened at the Royal College of Ophthalmologists London headquarters in June 2018. In total, 29 stakeholders attended the meeting. The professional characteristics (...) of stakeholders included but were not limited to: ophthalmologists, patients, religious leaders, ethicists, lawyers and commissioners. Thematic qualitative analysis using methodology proposed by Braun and Clarke was conducted on the resultant transcript of the discussion.ResultsThemes identified include: beneficence and non-maleficence ; autonomy ; distributive justice.ConclusionThis analysis provides a reference point for the ethical factors surrounding ISBCS. The stakeholders concluded that this approach was an ethical undertaking provided patient autonomy was appropriately attained. This requires a patient’s interpretation of the risk-benefit balance, which must include an understanding of the low but unquantifiable risk of severe complications. A surgeon must aim to minimise risks through the adaption of accepted surgical protocols and by performing appropriate patient selection. Currently, cost savings to healthcare that may occur following the implementation of ISBCS should be considered a secondary benefit of the protocol. (shrink)

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

An important component of souls is the capacity for free will, as the origin of agency within an individual. Belief in souls arises in part from the experience of conscious will, a compelling feeling of personal causation that accompanies almost every action we take, and suggests that an immaterial self is in charge of the physical body.

Marxism, one of the few philosophies that turned into an effective movement, not so long ago was the official ideology in one form or another of much of humanity. It was promulgated, initially by the Soviet Union, then imposed on much of Central and Eastern Europe, later emerged in the People's Republic of China, and gradually spread to other parts of Asia and even bits of Africa and Latin America. Although declining in its initial popularity, it still remains strong in (...) several countries and is supported by numerous communist and other parties and countless individuals around the world. The Historical Dictionary of Marxism covers the history of Marxism and all its thinkers and schools of thought in a comprehensive manner. This is done, through a chronology, a list of acronyms and abbreviations, an introductory essay, a bibliography, and hundreds of cross-reference dictionary entries on basic terms and concepts, significant thinkers and doers, and also the parties and countries that followed it. (shrink)

The A to Z of Marxism covers the history of Marxism and all its thinkers and schools of thought in a comprehensive manner. This is done, through a chronology, an introductory essay, a bibliography, and hundreds of cross-reference dictionary entries on basic terms and concepts, significant thinkers and doers, and also the parties and countries that followed it.

Depuis Galilée et son affirmation que le Grand Livre de la Nature est écrit en langage mathématique, la science a été une mathématisation progressive des données sensibles fournies par l'observation. Malgré la réticence des philosophes à assumer cet état, certains acceptèrent pourtant de passer par ce détour formel de la mathesis. Car il ne s'agissait plus de se livrer aux méditations faciles sur les formes géométriques, mais de se confronter dorénavant à la rudesse abstraite du langage algébrique. Certes, la démarche (...) réserve aussi le plaisir de comprendre et révèle d'autres harmonies. Mais la marche est difficile. On sait combien certains physiciens du XVIIIe siècle ont protesté contre la pénétration de leur discipline par la puissance de l'analyse. Rapidement, nul ne put être physicien qui ne maîtrisait pas le calcul infinitésimal. La chimie, la biologie plus tard, l'information n'ont pas échappé à la mathématisation. Les compositions géométriques, auxquelles Pascal géomètre restait attaché, devaient laisser la place à l'équation différentielle. Le hasard, l'incertitude même n'échappèrent ni au calcul ni à la formule. La science a substitué à l'élégance du discours celle de la preuve, à l'enchaînement des arguments celui des équations. Le sensible, cette présence originaire au monde, ne peut aujourd'hui accéder à l'objectivité qu'au travers de procédures algébriques qui tracent sur sa chair les lignes de force et d'intelligence qui nous en assurent la compréhension. Il y a là tin défi que la science s'occupe à relever depuis plus de trois cents ans. Il faut bien que la philosophie, sur son mode propre, relève à son tour le même défi. Nous voilà contraints de penser la pensée mathématique du monde. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

BackgroundTrial registration helps minimize publication and reporting bias. In leading medical journals, 96% of published trials are registered. The aim of this study was to determine the proportion of randomized controlled trials published in key nursing journals that met criteria for timely registration.MethodsWe reviewed all RCTs published in three (two general, one mental health) nursing journals between August 2011 and September 2016. We classified the included trials as: 1. Not registered, 2. Registered but not reported in manuscript, 3. Registered retrospectively, (...) 4. Registered prospectively (before the recruitment of the first subject into the trial). 5. Timely registration (as 4 but the trial identification number is reported in abstract).ResultsWe identified 135 trials published in the three included journals. The majority (n = 78, 58%) were not registered. Thirty-three (24%) were retrospectively registered. Of the 24 (18%) trials that were prospectively registered, 11 (8%) met the criteria for timely registration.ConclusionsThere is an unacceptable difference in rates of trial registration between leading medical and nursing journals. Concerted effort is required by nurse researchers, reviewers and journal editors to ensure that all trials are registered in a timely way. (shrink)

Developmental systems theory (DST) is a general theoretical perspective on development, heredity and evolution. It is intended to facilitate the study of interactions between the many factors that influence development without reviving `dichotomous' debates over nature or nurture, gene or environment, biology or culture. Several recent papers have addressed the relationship between DST and the thriving new discipline of evolutionary developmental biology (EDB). The contributions to this literature by evolutionary developmental biologists contain three important misunderstandings of DST.

In _Narcissus Transformed_, Gray Kochhar-Lindgren interprets Narcissus as thematizing the tragic situation of the postmodern subject. After showing the connections between Cartesian philosophy and narcissism, he proceeds to lay out the function of Narcissus as a poetic figure of discourse in the fields of psychoanalysis and modern fiction. He moves beyond the description of narcissism to an interpretation of the conditions necessary for Narcissus, the beautiful boy captivated by his own image, to become a different kind of subject. The (...) topos of narcissism, which is first articulated by Ovid, always includes within itself a mirror, a gap, self-referential desire, and death—all of which culminate in Narcissus's inability to make space for an Other. Kochhar-Lindgren contends that this is the founding topos of modern philosophy, which is then incorporated into and transmuted by the disciplines of psychoanalysis and fiction. With the extensive work of Freud on narcissism, it becomes a central concept for psychoanalysis; and with Lacan's interpretation of the narcissist as phantom, statue, and automaton, narcissism moves into a specifically textual interpretation of subjectivity. Kochhar-Lindgren then provides close readings of fictional texts-—_The Waves_ by Virginia Woolf, _The Ogre _by Michel Tournier, and _Daniel Martin_ by John Fowles—to show more explicitly the textual construction of the narcissistic subject and to suggest ways that Narcissus might be transformed into a subject not held in thrall to the "glassy-eyed stare of Thanatos." He concludes with an enactment, from a Lacanian and fictional perspective, of the beginnings of the undoing of the narcissistic topos of contemporary culture. Narcissus steps from the self-reflective mirror into a theater; he stops longing to be a purely self-reflexive work in order to become part of the play of a text. (shrink)

In this paper I examine the psychological traits that can play a constitutive role in having an evil character, using a recent affect-based account by Colin McGinn as my starting point. I distinguish several such traits and defend the importance of both affect and action-based approaches. I then argue that someone who possesses these characteristics to the greatest possible extent—the purely evil individual—can actually be less depraved than one whose character is not so thoroughly penetrated by such traits. To illustrate (...) the contrast I have in mind, I use two fictional characters, each of whom exemplifies a different kind of moral extreme: Claggart, from Melville’s Billy Budd, and Wilde’s Dorian Gray. (shrink)

Gray's target article presents a model of consciousness that includes several ideas similar to those developed over the past century to explain how sensorimotor information is interpreted by the nervous system. This commentary discusses these ideas and introduces some additional hypotheses, also derived from sensorimotor investigations, that might help improve Gray's model.

A great deal of interest and excitement surround the interface between the philosophy of biology and the philosophy of psychology, yet the area is neither well defined nor well represented in mainstream philosophical publications. This book is perhaps the first to open a dialogue between the two disciplines. Its aim is to broaden the traditional subject matter of the philosophy of biology while informing the philosophy of psychology of relevant biological constraints and insights.The book is organized around six themes: functions (...) and teleology, evolutionary psychology, innateness, philosophy of mind, philosophy of science, and parallels between philosophy of biology and philosophy of mind. Throughout, one finds overlapping areas of study, larger philosophical implications, and even larger conceptual ties. Woven through these connections are shared concerns about the status of semantics, scientific law, evolution and adaptation, and cognition in general. Contributors André Ariew, Mark A. Bedau, David J. Buller, Paul Sheldon Davies, Stephen M. Downes, Charbel Niño El-Hani, Owen Flanagan, Peter Godfrey-Smith, Todd Grantham, Valerie Gray Hardcastle, Gary Hatfield, Daniel W. McShea, Karen Neander, Shaun Nichols, Antonio Marcos Pereira, Tom Polger, Lawrence A. Shapiro, Kim Sterelny, Robert A. Wilson, William C. Wimsatt. (shrink)

The present note offers a proof for separating the truth-values of an arbitrary finitely many valued Łukasiewicz logic by making use of Gray codes.

Prompted by a 2019 essay by Jonathan Moreno in the Hastings Center Report, the Center's board of directors undertook a careful examination of the name of its preeiminent award, the Henry Knowles Beecher Award, which has been given to twenty‐nine individuals who have made lifetime contributions to bioethics. citing new research that revealed that Beecher's earlier experimentation on drugs had involved nonconsenting adults, Moreno urged the Center to reevaluate honoring Beecher through this award. After reviewing the relevant published evidence and (...) holding extensive discussions, the board decided to rename the award. We also took the opportunity to reframe the award to emphasize quality of scholarship and impact on thinking, practice, and policy rather than lifetime achievement. The new name—the Founders’ Award of The Hastings Center—reflects our desire to honor not only the Center's cofounders, Daniel Callahan and Willard Gaylin, but also others who helped found the field of bioethics. With great pride, the Center has announced that Patricia King of the Georgetown University Law Center is the 2021 recipient of the Founders’ Award. A distinguished civil rights lawyer, King was instrumental in ensuring justice as one of the three principles of The Belmont Report. (shrink)

We conducted a systematic review and meta-analysis of anonymous surveys asking scientists whether they ever committed various forms of plagiarism. From May to December 2011 we searched 35 bibliographic databases, five grey literature databases and hand searched nine journals for potentially relevant studies. We included surveys that asked scientists if, in a given recall period, they had committed or knew of a colleague who committed plagiarism, and from each survey extracted the proportion of those who reported at least one case. (...) Studies that focused on academic plagiarism were excluded. Literature searches returned 12,460 titles from which 17 relevant survey studies were identified. Meta-analysis of studies reporting committed and witnessed plagiarism yielded a pooled estimate of, respectively, 1.7 % and 30 %. Basic methodological factors, including sample size, year of survey, delivery method and whether survey questions were explicit rather than indirect made a significant difference on survey results. Even after controlling for these methodological factors, between-study differences in admission rates were significantly above those expected by sampling error alone and remained largely unexplained. Despite several limitations of the data and of this meta-analysis, we draw three robust conclusions: The rate at which scientists report knowing a colleague who committed plagiarism is higher than for data fabrication and falsification; The rate at which scientists report knowing a colleague who committed plagiarism is correlated to that of fabrication and falsification; The rate at which scientists admit having committed either form of misconduct in surveys has declined over time. (shrink)

Carbon monoxide intoxication leads to acute and chronic neurological deficits, but little is known about the specific noxious mechanisms. 1 H magnetic resonance spectroscopy may allow insight into the pathophysiology of CO poisoning by monitoring neurochemical disturbances, yet only limited information is available to date on the use of this protocol in determining the neurological effects of CO poisoning. To further examine the short-term and long-term effects of CO on the central nervous system, we have studied seven patients with CO (...) poisoning assessed by gray and white matter MRS, magnetic resonance imaging and neuropsychological testing. Five patients suffered from acute high-dose CO intoxication and were in coma for 1–6 days. In these patients, MRI revealed hyperintensities of the white matter and globus pallidus and also showed increased choline and decreased N -acetyl aspartate ratios to creatine, predominantly in the white matter. Lactate peaks were detected in two patients during the early phase of high-dose CO poisoning. Two patients with chronic low-dose CO exposure and without loss of consciousness had normal MRI and MRS scans. On follow-up. five of our seven patients had long-lasting intellectual impairment, including one individual with low-dose CO exposure. The MRS results showed persisting biochemical alterations despite the MRI scan showing normalization of morphological changes. In conclusion, the MRS was normal in patients suffering from chronic low-dose CO exposure; in contrast, patients with high-dose exposure showed abnormal gray and white matter levels of NAA/Cr, Cho/Cr and lactate, as detected by 1 H MRS, suggesting disturbances of neuronal function, membrane metabolism and anaerobic energy metabolism, respectively. Early increases in Cho/Cr and decreases of NAA/Cr may be related to a poor long-term outcome, but confirmation by future studies is needed. (shrink)

Gray mistakenly thinks I have rejected the sort of theoretical enterprise he is undertaking, because, according to him, I think that "more data" is all that is needed to resolve all the issues. Not at all. My stalking horse was the bizarre (often pathetic) claim that no amount of empirical, "third-person point-of-view" science (data plus theory) could ever reduce the residue of mystery about consciousness to zero. This "New Mysterianism" (Flanagan, 1991) is one that he should want to combat (...) as vigorously as I have done. (shrink)

In Isaiah Berlin, John Gray interprets Berlin as having made value pluralism the basis of an anti‐rationalist, “agonistic” liberalism. Gray argues that Berlin's value pluralism actually stands in tension with his liberalism, and that a whole‐hearted affirmation of value pluralism should have led him to reject the claim that liberal institutions are morally superior. But Berlin's pluralism is more moderate than that ascribed to him by Gray, in that it does not allow for diminishing the value of (...) liberty beyond a certain point. This version of pluralism is more compatible with the objectivity Gray claims for pluralism than is his own version. (shrink)

One ethical issue that commonly comes up in clinical practice is the negotiation of fees with clients. Although the APA Ethics Code provides standards regarding clients who are unable to or do not pay, little guidance is given pertaining to fee limits for clients who want to pay more. This issue is explored using a real case example, including the relevant ethical codes to be considered. The necessary “gray” areas of ethical decision-making are demonstrated through my own decision process. (...) Implications for future scenarios are discussed. (shrink)

Developmental systems theory is an attempt to sum up the ideas of a research tradition in developmental psychobiology that goes back at least to Daniel Lehrman’s work in the 1950s. It yields a representation of evolution that is quite capable of accommodating the traditional themes of natural selection and also the new results that are emerging from evolutionary developmental biology. But it adds something else - a framework for thinking about development and evolution without the distorting dichotomization of biological processes (...) into gene and non-gene and the vestiges of the ‘black-boxing’ of developmental processes in the modern synthesis, such as the asymmetric use of the concept of information. Phenomena that are marginalized in current gene-centric conceptions, such as extra-genetic inheritance, niche construction and phenotypic plasticity are placed center stage. (shrink)

IntroductionCerebral visual impairment is an important cause of visual impairment in western countries. Perinatal hypoxic-ischemic damage is the most frequent cause of CVI but CVI can also be the result of a genetic disorder. The majority of children with CVI have cerebral palsy and/or developmental delay. Early diagnosis is crucial; however, there is a need for consensus on evidence based diagnostic tools and referral criteria. The aim of this study is to develop guidelines for diagnosis and referral in CVI according (...) to the grade method.Patients and MethodsWe developed the guidelines according to the GRADE method 5 searches on CVI were performed in the databases Medline, Embase, and Psychinfo, each with a distinct topic.ResultsBased on evidence articles were selected on five topics: 1. Medical history and CVI-questionnaires 23. 2. Ophthalmological and orthoptic assessment 37. 3. Neuropsychological assessment 5. 4. Neuroradiological evaluation and magnetic resonance imaging 9. 5. Genetic assessment 5.ConclusionIn medical history taking, prematurity low birth weight and APGAR Scores are important. Different questionnaires are advised for children under the age of 3 years, older children and for specific risk groups. In ophthalmological examination, eye movements, specially saccades, accommodation, crowding, contrast sensitivity and visual fields should be evaluated. OCT can show objective signs of trans-synaptic degeneration and abnormalities in fixation and saccades can be measured with eye tracking. Screening of visual perceptive functioning is recommended and can be directive for further assessment. MRI findings in CVI in Cerebral Palsy can be structured in five groups: Brain maldevelopment, white and gray matter lesions, postnatal lesions and a normal MRI. In children with CVI and periventricular leukomalacia, brain lesion severity correlates with visual function impairment. A differentiation can be made between cortical and subcortical damage and related visual function impairment. Additional assessments can be necessary to complete the diagnosis of CVI and/or to reveal the etiology. (shrink)

This paper aims to study the role of the social robot Probo in providing assistance to a therapist for robot assisted therapy (RAT) with autistic children. Children with autism have difficulties with social interaction and several studies indicate that they show preference toward interaction with objects, such as computers and robots, rather than with humans. In 1991, Carol Gray developed Social Stories, an intervention tool aimed to increase children's social skills. Social stories are short scenarios written or tailored for (...) autistic individuals to help them understand and behave appropriately in social situations. This study shows that, in specific situations, the social performance of autistic children improves when using the robot Probo, as a medium for social story telling, than when a human reader tells the stories. The robot tells Social Stories to teach ASD children how to react in situations like saying “hello“, saying “thank you“ and “sharing toys“. The robot has the capability of expressing emotions and attention via its facial expressions and its gaze. The paper discusses the use of Probo as an added-value therapeutic tool for social story telling and presents the first experimental results. Keywords: social robot; ASD children; social story; robot assisted therapy. (shrink)

This paper aims to study the role of the social robot Probo in providing assistance to a therapist for robot assisted therapy with autistic children. Children with autism have difficulties with social interaction and several studies indicate that they show preference toward interaction with objects, such as computers and robots, rather than with humans. In 1991, Carol Gray developed Social Stories, an intervention tool aimed to increase children’s social skills. Social stories are short scenarios written or tailored for autistic (...) individuals to help them understand and behave appropriately in social situations. This study shows that, in specific situations, the social performance of autistic children improves when using the robot Probo, as a medium for social story telling, than when a human reader tells the stories. The robot tells Social Stories to teach ASD children how to react in situations like saying “hello”, saying “thank you” and “sharing toys”. The robot has the capability of expressing emotions and attention via its facial expressions and its gaze. The paper discusses the use of Probo as an added-value therapeutic tool for social story telling and presents the first experimental results. Keywords: social robot; ASD children; social story; robot assisted therapy. (shrink)

This paper aims to study the role of the social robot Probo in providing assistance to a therapist for robot assisted therapy with autistic children. Children with autism have difficulties with social interaction and several studies indicate that they show preference toward interaction with objects, such as computers and robots, rather than with humans. In 1991, Carol Gray developed Social Stories, an intervention tool aimed to increase children’s social skills. Social stories are short scenarios written or tailored for autistic (...) individuals to help them understand and behave appropriately in social situations. This study shows that, in specific situations, the social performance of autistic children improves when using the robot Probo, as a medium for social story telling, than when a human reader tells the stories. The robot tells Social Stories to teach ASD children how to react in situations like saying “hello”, saying “thank you” and “sharing toys”. The robot has the capability of expressing emotions and attention via its facial expressions and its gaze. The paper discusses the use of Probo as an added-value therapeutic tool for social story telling and presents the first experimental results. Keywords: social robot; ASD children; social story; robot assisted therapy. (shrink)

Regular musical activity as a complex multimodal lifestyle activity is proposed to be protective against age-related cognitive decline and Alzheimer’s disease. This cross-sectional study investigated the association and interplay between musical instrument playing during life, multi-domain cognitive abilities and brain morphology in older adults from the DZNE-Longitudinal Cognitive Impairment and Dementia Study study. Participants reporting having played a musical instrument across three life periods were compared to controls without a history of musical instrument playing, well-matched for reserve proxies of education, (...) intelligence, socioeconomic status and physical activity. Participants with musical activity outperformed controls in global cognition, working memory, executive functions, language, and visuospatial abilities, with no effects seen for learning and memory. The musically active group had greater gray matter volume in the somatosensory area, but did not differ from controls in higher-order frontal, temporal, or hippocampal volumes. However, the association between gray matter volume in distributed frontal-to-temporal regions and cognitive abilities was enhanced in participants with musical activity compared to controls. We show that playing a musical instrument during life relates to better late-life cognitive abilities and greater brain capacities in OA. Musical activity may serve as a multimodal enrichment strategy that could help preserve cognitive and brain health in late life. Longitudinal and interventional studies are needed to support this notion. (shrink)

A 20th anniversary edition of the art classic that celebrates the intersection of creative expression and spirituality—from one of the greatest living artists of our time Twenty years after the original publication of The Mission of Art, Alex Grey’s inspirational message affirming art’s power for personal catharsis and spiritual awakening is stronger than ever. In this special anniversary edition, Grey—visionary painter, spiritual leader, and best-selling author—combines his extensive knowledge of art history with his own experiences in creating art at the (...) boundaries of consciousness. Grey examines the roles of conscience and intention in the creative process, including practical techniques and exercises useful in exploring the spiritual dimensions of art. Challenging and thought-provoking, The Mission of Art will be appreciated by everyone who has ever contemplated the deeper purpose of creative expression. (shrink)

Why is the human imagination to blame for the worst crimes of the twentieth century? Why is progress a pernicious myth? Why is contemporary atheism just a hangover from Christian faith? John Gray, author of Straw Dogsand Black Mass, is one of the most original and iconoclastic thinkers of our time. In this pugnacious and brilliantly readable collection of essays from across his career, he smashes through humanity's most cherished beliefs to overturn our view of the world, and our (...) place in it. 'If humans are different from other animals it is chiefly in being governed by myths, which are not creations of the will but creatures of the imagination.' 'No traditional myth is as untruthful as the modern myth of progress. All prevailing philosophies embody the fiction that human life can be altered at will. Better aim for the impossible, they say, than submit to fate. Invariably, the result is a cult of human self-assertion that soon ends in farce.'. (shrink)

A pioneering work in the philosophy of mind, Content and Consciousness brings together the approaches of philosophers and scientists to the mind--a connection that must occur if genuine analysis of the mind is to be made. This unified approach permits the most forbiddingly mysterious mental phenomenon--consciousness--to be broken down into several distinct phenomena, and these are each given a foundation in the physical activity of the brain. This paperback edition contains a preface placing the book in the context of recent (...) work in the area. (shrink)

There is a belief that exercise has a major role to play in the current health and wellbeing agendas. Consequently, health interventions are implemented based upon the recommendations of the ACSM and similar exercise research organizations. However this development has been challenged through both social and political perspectives. Specifically accusations of medicalization have been raised against the increasing relationship between the exercise and medical domains. The purpose of this article is to present a similar critique of the growing emergence of (...) a medical paradigm within the exercise domain. In this instance the focus will examine the relationship between exercise professional, exercise science and the proposed medical paradigm. Through the use of philosophical essay and systematic review of literature, it is argued that a continuing shift by exercise science to mirror the medical paradigm will cause a number of issues and potential hazards in the working practices of its professionals. (shrink)

A great philosopher will change the way you think about your life. For most of human history, religion provided a clear explanation of life and death. But in the late 19th and early 20th centuries new ideas -- from psychiatry to evolution to Communist -- seemed to suggest that our fate was now in our own hands. We would ourselves become God. This is the theme of a remarkable new book by one of the world's greatest lving philosophers. It is (...) a brilliant and frightening look at the problems and opportunities of a world coming to grips with humankind's now solitary, unaided place in the universe. Gray takes two major examples: the belief that the science-backed Communism of the new USSR could reshape the planet, and the belief among a group of Edwardian intellectuals -- popularized through mediums and automatic writing -- that there was a non-religious form of life after death. Gray presents an extraordinary cast of philosophers, journalists, politicians, charlatans and mass murderers, all of whom felt driven by a specifically scientific and modern world view. He raises a host of fascinating questions about what it means to be human. The implications of Gray's book will haunt its readers for the rest of their lives. (shrink)

In this book by the award-winning author of Just Healthcare, Norman Daniels develops a comprehensive theory of justice for health that answers three key questions: what is the special moral importance of health? When are health inequalities unjust? How can we meet health needs fairly when we cannot meet them all? Daniels' theory has implications for national and global health policy: can we meet health needs fairly in ageing societies? Or protect health in the workplace while respecting individual liberty? Or (...) meet professional obligations and obligations of justice without conflict? When is an effort to reduce health disparities, or to set priorities in realising a human right to health, fair? What do richer, healthier societies owe poorer, sicker societies? Just Health: Meeting Health Needs Fairly explores the many ways that social justice is good for the health of populations in developed and developing countries. (shrink)

Frege's Puzzle is a founding problem in analytic philosophy. It lies at the intersection of central topics in the philosophy of language and mind: the theory of reference, the nature of propositional attitudes, the nature of semantic theorizing, the relation between semantics and pragmatics, etc. This chapter is an overview of the puzzle and of the space of contemporary approaches to it.

In this book Daniel Wegner offers a novel understanding of the relation of consciousness, the will, and our intentional and voluntary actions. Wegner claims that our experience and common sense view according to which we can influence our behavior roughly the way we experience that we do it is an illusion.