Conflicts of interest. None to report Healthcare is a context where individuals with disability confront important ethical and social challenges. Adolescents and young adults with cerebral palsy (CP) seem to face additional challenges but we have little insight into their perspectives. This qualitative study aimed to identify and better understand such challenges. We interviewed 14 participants with CP aged 18 to 25. Participants described a range of challenges experienced when using health services, including: lack of long-term follow-up, shortcomings in physical (...) access to infrastructures, and situations of injustice. Challenges specific to medical consultations were reported (e.g., rude attitudes, belittlement, inadequate communication, lack of consideration). We discuss and explain further that: (1) the ethical principle of respect for persons needs to be concretely specified to improve current practices; (2) respect for autonomy calls for further direct empowerment of individuals with CP and, (3) gaps in dedicated healthcare resources for CP and the long-term needs associated should be addressed. (shrink)

This article investigates how the meanvariance efficient frontier defined by sovereign bonds of 20 developed countries is affected by the consideration of socially responsible indicators for countries in investment decision-making. For a global rating of socially responsible performances, we show that it is possible to build portfolios with an increased average rating without significantly harming the risk/return relationship. This result differs when considering sub-ratings related to the environment, social concerns and public governance. The results are good news for responsible investors (...) and suggest that socially responsible portfolios of sovereign bonds can be built without a significant loss of mean-variance efficiency. (shrink)

This article analyzes the operations of the French group Lafarge in Syria during the civil war between 2011 and 2014, to understand the conflict-sensitive practices of a multinational company (MNC) in an area of limited statehood (ALS). We examine how and why the company decided to continue operating its plant in Syria during this intrastate conflict, resulting in financing terrorist groups like ISIS. We highlight the key operational and managerial decisions made by headquarters and local operations and relate them to (...) the conflict situation in the ALS in question. We contribute, with the idea of the firm’s “organization of short-sightedness,” to the understanding of how strategic decisions may lead to a structural inability to fully comprehend the local dangers and the implications for the employees, and how this may lead to a redefinition of legitimate and illegitimate stakeholders in conflict zones. A drawn-out process, stemming from a willingness to stay at all cost in an ALS environment, leads to misinterpretation of the danger and an acute dependency on local stakeholders. (shrink)

Research in communication studies has suggested that Al-Jazeera produces different versions of news stories for different audiences. Yet, examining the linguistic means used to create these versions has remained under-researched. Drawing on Fairclough’s three-dimensional model (1992) and Halliday’s Transitivity Model (1985), this study aims at exploring how Al-Jazeera Arabic (AJA) and Al-Jazeera English (AJE) discursively represented the participants involved in the 2022 Russo-Ukrainian conflict in headlines. The analysis of transitivity patterns in AJA and AJE headlines reveals both similar and different (...) representations of the conflict. Although they avoided negative labeling of the Russian government, both channels ascribed conflict escalation to it, highlighting civilians suffering and protesting. Nevertheless, while AJE emphasized the Ukrainian government vulnerability, AJA presented the conflict as a confrontation between two symmetrical forces. Similarities are attributed to organizational and social institutional forces, while differences result from different editorial policies and audience preferences. As discursive and social practices, the headlines contribute to shaping audience perceptions of the conflict, with AJA challenging the prevailing western narrative of the conflict while AJE reinforcing it. (shrink)

Dana S. Belu combines Heidegger's phenomenology of technology with feminist phenomenology in order to make sense of the increased technicization of women's reproductive bodies during conception, pregnancy, and birth.

This chapter examines how the problem of the nature of body had become the central debate in the field of natural philosophy in England by the middle of the seventeenth century. It explains that the nature of the physical body is one of the major problems of seventeenth-century natural philosophy and that it began, at least in part, as a byproduct of a change in the philosophical vocabulary. The chapter also evaluates solutions proposed to address the problem concerning the nature (...) of body, including those derived from theory of matter and mixed mathematics. (shrink)

Physicien de formation, Francois Bastien a enseigne dans de nombreux domaines: mathematiques, electricite, optique, thermodynamique, physique des vibrations, physique des capteurs, acoustique des solides, informatique, electronique numerique et electrotechnique. Il a tenu un blog ou se sont regroupees certaines interrogations sur les sciences exactes. Son livre presente donc des reflexions sur la recherche scientifique. Un changement d'echelle de la communaute scientifique entraine necessairement un bouleversement. L'auteur tend a sortir de la doctrine hors de l'ecole point de salut qui freine (...) la promotion sociale, en proposant par exemple un Musee de la Science inconnue. Il invite egalement a lutter contre les effets de la multiplication des publications scientifiques, en faisant naitre des journaux de critiques scientifiques comme il en existe pour la litterature. Par ailleurs, la prise en compte des limites de la science, d'un point de vue philosophique et pratique, est discutee. (shrink)

Hermann Cohen (1842-1918) was a leading figure in the Neo- Kantian philosophical movement that dominated European thought before 1918. He was also an inaugural figure in modern Jewish philosophy in the twentieth and twenty-first centuries. This book explores Cohen's striking claim that ethics is rooted in law - a claim developed both in his philosophical ethics and his philosophy of Judaism, in particular in his writings on "love-of-neighbor," up to and including his well-known Religion of Reason. Dana Hollander proposes that (...) neither Cohen's systematic philosophy nor his "Jewish" philosophy should be seen as the dominant framework for his oeuvre as a whole, but that his understanding of key philosophical questions take shape in the passages between both corpuses, a trait that could be seen as paradigmatic for modern Jewish philosophy. Ethics Out of Law taps into one of the prime topics of current interest in the field of Jewish philosophy: the nature of Jewish political existence and the changing configurations of "law" that this entails. (shrink)

« Tout être humain désire une vie de qualité, c’est même là un souci ultime et constant. Peu importe qu’on la dise “bonne”, “réussie” ou “authentique”, c’est toujours à partir d’une certaine perception de la qualité que nous entreprenons nos projets, organisons nos discours sur le monde et accomplissons nos moindres gestes. Mais quelles sont les conditions d’une telle vie? Existe-t-il des critères permettant de l’évaluer? C’est en réponse à de telles interrogations qu’ont émergé les grandes réflexions de l’humanité sur (...) le beau, le bien et le vrai, tout comme l’intuition d’une continuité subtile entre ces idéaux, de même que les préoccupations pratiques sur la façon de conduire sa vie. Et c’est à l’horizon de ces idéaux que nous formulons encore les débats et nos conceptions sur la nature de l’expérience esthétique et de l’art, de l’éthique et de la morale, de la science et de la connaissance en général. Ainsi comprise, l’idée selon laquelle il existe un lien profond entre expérience esthétique, requêtes de l’éthique et objectifs de la connaissance est à la fois la plus ancienne et la plus actuelle des intuitions, comme l’attestent ces contrées de l’expérience quotidienne où qualités esthétiques et éthiques interagissent et s’alimentent mutuellement, tantôt en concordance harmonieuse, tantôt en discordance créatrice, et où la connaissance retrouve ses plus nobles alliés dans l’art ou la poésie. »C’est cette intuition que l’auteur s’attache à redéployer en en suivant la permanence et la profondeur chez des témoins et des commentateurs aussi illustres que Paul Ricoeur, John Dewey, R. W. Emerson, Jean-Marie Guyau, Friedrich Nietzsche, Henri Bergson, Nishida Kitaro, Mikel Dufrenne et Martha C. (shrink)

Cet article cherche à rendre compte de la dynamique du réseau scientifique de chercheurs, observé à travers l’activité de publication, à l’échelle des carrières individuelles. Empiriquement, nous avons reconstitué le réseau de cosignature de publications de cinq chimistes émérites de l’Université de Poitiers et nous avons repéré les moments d’émergence, de renforcement ou d’affaiblissement des relations de ces chimistes avec leurs coauteurs. Ce travail, à visée exploratoire et compréhensive, repose sur une méthodologie originale combinant matériaux quantitatifs et qualitatifs : alors (...) que des données de publication fournissent des informations exhaustives sur les relations de co-authorship des chercheurs, les CV et entretiens semi-directifs réalisés auprès des protagonistes permettent d’analyser finement cette dynamique relationnelle au fil de leur carrière. (shrink)

Graphical AbstractUsing the indices δ+ and δ* for assessing phylogenetic diversity may lead to spurious results and interpretations; it can bias recommendations for conservation and lead to inappropriate management decisions. Therefore these indices should be avoided and other indices based on quadratic entropy (Qδ+ and Q) should be used instead.

Deciding between different voluntary movements implies a continuous control of the competition between potential actions. Many theories postulate a leading role of prefrontal cortices in this executive function, but strong evidence exists that a motor region like the primary motor cortex is also involved, possibly via inhibitory mechanisms. This was already shown during the pre-movement decision period, but not after movement onset. For this pilot experiment we designed a new task compatible with the dynamics of post-onset control to study the (...) silent period duration, a pause in electromyographic activity after single-pulse transcranial magnetic stimulation that reflects inhibitory mechanisms. A careful analysis of the SP during the ongoing movement indicates a gradual increase in inhibitory mechanisms with the level of competition, consistent with an increase in mutual inhibition between alternative movement options. However, we also observed a decreased SP duration for high-competition trials associated with change-of-mind inflections in their trajectories. Our results suggest a new post-onset adaptive process that consists in a transient reduction of GABAergic inhibition within M1 for highly conflicting situations. We propose that this reduced inhibition softens the competition between concurrent motor options, thereby favoring response vacillation, an adaptive strategy that proved successful at improving behavioral performance. (shrink)

An Introduction to Proof via Inquiry-Based Learning is a textbook for the transition to proof course for mathematics majors. Designed to promote active learning through inquiry, the book features a highly structured set of leading questions and explorations. The reader is expected to construct their own understanding by engaging with the material. The content ranges over topics traditionally included in transitions courses: logic, set theory including cardinality, the topology of the real line, a bit of number theory, and more. The (...) exposition guides and mentors the reader through an adventure in mathematical discovery, requiring them to solve problems, conjecture, experiment, explore, create, and communicate. Ultimately, this is really a book about productive struggle and learning how to learn. This is a print version of the popular open-access online text by Dana C. Ernst. (shrink)

Background: Current practice frequently fails to provide care consistent with the preferences of decisionally-incapacitated patients. It also imposes significant emotional burden on their surrogates. Algorithmic-based patient preference predictors (PPPs) have been proposed as a possible way to address these two concerns. While previous research found that patients strongly support the use of PPPs, the views of surrogates are unknown. The present study thus assessed the views of experienced surrogates regarding the possible use of PPPs as a means to help make (...) treatment decisions for decisionally-incapacitated patients. -/- Methods: This qualitative study used semi-structured interviews to determine the views of experienced surrogates [n=26] who were identified from two academic medical centers and two community hospitals. The primary outcomes were respondents’ overall level of support for the idea of using PPPs and the themes related to their views on how a PPP should be used, if at all, in practice. -/- Results: Overall, 21 participants supported the idea of using PPPs. The remaining five indicated that they would not use a PPP because they made decisions based on the patient’s best interests, not based on substituted judgment. Major themes which emerged were that surrogates, not the patient’s preferences, should determine how treatment decisions are made, and concern that PPPs might be used to deny expensive care or be biased against minority groups. -/- Conclusions: Surrogates, like patients, strongly support the idea of using PPPs to help make treatment decisions for decisionally-incapacitated patients. These findings provide support for developing a PPP and assessing it in practice. At the same time, patients and surrogates disagree over whose preferences should determine how treatment decisions are made, including whether to use a PPP. These findings reveal a fundamental disagreement regarding the guiding principles for surrogate decision-making. Future research is needed to assess this disagreement and consider ways to address it. (shrink)

The cerebral cortex is a rich and diverse structure that is the basis of intelligent behavior. One of the deepest mysteries of the function of cortex is that neural processing times are only about one hundred times as fast as the fastest response times for complex behavior. At the very least, this would seem to indicate that the cortex does massive amounts of parallel computation.This paper explores the hypothesis that an important part of the cortex can be modeled as a (...) connectionist computer that is especially suited for parallel problem solving. The connectionist computer uses a special representation, termed value unit encoding, that represents small subsets of parameters in a way that allows parallel access to many different parameter values. This computer can be thought of as computing hierarchies of sensorimotor invariants. The neural substrate can be interpreted as a commitment to data structures and algorithms that compute invariants fast enough to explain the behavioral response times. A detailed consideration of this model has several implications for the underlying anatomy and physiology. (shrink)

The Rei(g)n of Rule is a study of rules and their role in language. Rules have dominated the philosophical arena as a fundamental philosophical concept. Little progress, however, has been made in reaching an accepted definition of rules. This fact is not coincidental. The concept of rule is expected to perform various, at times conflicting, tasks. Analyzing key debates and rule related discussions in the philosophy of language I show that typically rules are perceived and defined either as norms or (...) as conventions. As norms, rules perform the evaluative task of distinguishing between correct and incorrect actions. As conventions, rules describe how certain actions are actually undertaken. As normative and conventional requirements do not necessarily coincide, the concept of rule cannot simultaneously accommodate both. The impossibility to consistently define rule has gone unnoticed by philosophers, and it is in this sense that rule has also blocked philosophical attempts to explain language in terms of rules.". (shrink)

Much attention has been focused in recent years on the ethical acceptability of physicians receiving gifts from drug companies. Professional guidelines recognize industry gifts as a conflict of interest and establish thresholds prohibiting the exchange of large gifts while expressly allowing for the exchange of small gifts such as pens, note pads, and coffee. Considerable evidence from the social sciences suggests that gifts of negligible value can influence the behavior of the recipient in ways the recipient does not always realize. (...) Policies and guidelines that rely on arbitrary value limits for gift-giving or receipt should be reevaluated. (shrink)

Alex John London’s new book, For the Common Good: Philosophical Foundations of Research Ethics highlights the fact that establishing just social arrangements is not only a matter of incentivizing popular will to act for the common good; it also requires filling in informational gaps about which policies, arrangements, and interventions will advance the basic interests of members in an equitable, effective and efficient manner. Promoting justice requires, in part, acquiring the knowledge for how to do so. In developing this point, (...) London carefully traces these missteps in the main philosophical debates and then resuscitates the importance of questions of justice at the heart of research ethics. In doing so, it provides a transformative corrective for the field. This review critically examines one of the central pillars of London’s egalitarian research imperative approach: the way in which the social value of research is closely linked with minimizing uncertainty among reasonable experts. (shrink)

Freight transportation plays a critical role in improving company performance in the modern manufacturing industry. To reduce costs, companies must take advantage of the use of large vehicles. It caused fewer deliveries, but inventory costs and degradation quality are high. One of the joint economic lot size problems in supply chain is Integrated Single-Vendor Single-Buyer Inventory Problem. This study developed the I-SVSB-IP model that considers raw materials’ exponential quality degradation and transportation costs. The objective function of this research was to (...) maximize the Joint Total Profit. Three decision variables used were inventory cycle time, raw material ordering frequency, and frequency of delivery of finished products to buyers. This study proposed a sophisticated Chimp Optimization Algorithm procedure to solve the I-SVSB-IP problem. A case study on the food industry in Indonesia was presented to optimize the I-SVSB-IP. The results showed that the ChOA procedure had produced an optimal solution compared to the state-of-the-art algorithm. This study also demonstrated a sensitivity analysis of decision and transportation variables to cost, revenue, and JTP. The results show that increasing transport frequency of ordering raw materials and finished products to buyers enhances the total cost and reduces joint total profit. In addition, increasing the rate of quality degradation of raw materials reduces JTP. (shrink)

Nelkin presents a simple and natural account of freedom and moral responsibility which responds to the great variety of challenges to the idea that we are free and responsible, before ultimately reaffirming our conception of ourselves as agents. Making Sense of Freedom and Responsibility begins with a defense of the rational abilities view, according to which one is responsible for an action if and only if one acts with the ability to recognize and act for good reasons. The view is (...) compatibilist -- that is, on the view defended, responsibility is compatible with determinism -- and one of its striking features is a certain asymmetry: it requires the ability to do otherwise for responsibility when actions are praiseworthy, but not when they are blameworthy. In defending and elaborating the view, Nelkin questions long-held assumptions such as those concerning the relation between fairness and blame and the nature of so-called reactive attitudes such as resentment and forgiveness. Her argument not only fits with a metaphysical picture of causation -- agent-causation -- often assumed to be available only to incompatibilist accounts, but receives positive support from the intuitively appealing Ought Implies Can Principle, and establishes a new interpretation of freedom and moral responsibility that dovetails with a compelling account of our inescapable commitments as rational agents. (shrink)

To describe phenomena that occur at different time scales, computational models of the brain must incorporate different levels of abstraction. At time scales of approximately 1/3 of a second, orienting movements of the body play a crucial role in cognition and form a useful computational level embodiment level,” the constraints of the physical system determine the nature of cognitive operations. The key synergy is that at time scales of about 1/3 of a second, the natural sequentiality of body movements can (...) be matched to the natural computational economies of sequential decision systems through a system of implicit reference called deictic in which pointing movements are used to bind objects in the world to cognitive programs. This target article focuses on how deictic bindings make it possible to perform natural tasks. Deictic computation provides a mechanism for representing the essential features that link external sensory data with internal cognitive programs and motor actions. One of the central features of cognition, working memory, can be related to moment-by-moment dispositions of body features such as eye movements and hand movements. (shrink)

Présentation de cinq grands intellectuels catholiques. Réflexion sur la foi et la raison. Essai engagé et sujet à débat.

"De nos jours, la justice est omniprésente dans l’espace public. Elle nous interpelle sous diverses formes?: faits divers, procès qui enflamment l’opinion publique, jugements qui affectent la vie des citoyens ou qui changent le paysage institutionnel dans lequel nous évoluons, etc. En fait, la médiatisation de la justice joue depuis longtemps un rôle essentiel dans le débat public, la régulation sociale ou le jeu politique en Occident. En une vingtaine d’études, plusieurs facettes du lien entre justice et espaces publics sont (...) explorées, de la fin du Moyen Âge jusqu’au siècle dernier, en Europe comme au Canada?: usages politiques de la justice, enjeux sociaux révélés par l’intervention judiciaire, échos médiatiques du palais et mobilisation de l’opinion publique, rôle de la presse dans les représentations du crime et des criminels, critiques du pouvoir judiciaire et des forces policières. Cet ouvrage collectif montre à quel point l’institution judiciaire a contribué à la construction de l’espace public au fil de ses transformations séculaires, combien aussi la justice ne se conçoit qu’à travers les lieux du vivre-ensemble et les différentes expressions de l’opinion publique. Le lecteur est donc convié à suivre le fil d’une vaste interrogation sur la place que la justice a historiquement occupée dans la formation de la conscience publique des sociétés occidentales." Présentation de l'éditeur. (shrink)

Qu’est-ce que la circulation mondialisée des biens et des personnes fait à la musique? Deux choses apparemment contradictoires : l’uniformisation des styles et des moyens se conjugue avec leur renouvellement constant, les effets de contagion planétaire avec la multiplication des réappropriations locales. Autrement dit ce qui uniformise peut être aussi ce qui singularise. Ce paradoxe nous conduit à dérouler quelques fils, à suivre de proche en proche des « objets » circulants – un appareil numérique, un style musical, un groupe (...) de pratiques – de manière à saisir les modalités concrètes de leur circulation. Pour que ça circule, il faut que ça se connecte, ce qui ne va pas sans heurts, disputes, larsens, frottements, qui tous affectent voire transforment l’« objet » circulant. Point de circulation sans frictions et boucles de rétroaction et sans une multitude d’agents qui font que ça passe : nous croisons en cheminant des musiciens noise, mais aussi des benders, des shifters, des makers, des repairers. Ces figures de l’interconnexion globale sont également celles qui se glissent dans ses failles et amplifient ses différences. (shrink)

Which entities should be accepted as part of the furniture of the world, and which not? What are pseudo-objects, if they are not properly objects? This collection explores the answers given to these questions by some key philosophers throughout the 20th century. It brings together essays by leading scholars on a subject of central importance to both metaphysics and the history of philosophy.".

It is argued that once biological systems reach a certain level of complexity, mechanistic explanations provide an inadequate account of many relevant phenomena. In this article, I evaluate such claims with respect to a representative programme in systems biological research: the study of regulatory networks within single-celled organisms. I argue that these networks are amenable to mechanistic philosophy without need to appeal to some alternate form of explanation. In particular, I claim that we can understand the mathematical modelling techniques of (...) systems biologists as part of a broader practice of constructing and evaluating mechanism schemas. This argument is elaborated by considering the case of bacterial chemotactic networks, where some research has been interpreted as explaining phenomena by means of abstract design principles. (shrink)