Introduction: Aristotle's phantasia and the ancient concept of imagination -- Visualization, vividness (enargeia) and realism -- Mathematical projection, copying and analogy -- Prophecy, inspiration and allegory -- Conclusion: ancient and modern imagination.

Why do people read novels, go to the theater, or listen to beautiful music? Do we seek out aesthetic experiences simply because we enjoy them--or is there another, deeper, reason we spend our leisure time viewing or experiencing works of art? Aesthetics, the first short introduction to the contemporary philosophy of aesthetics, examines not just the nature of the aesthetic experience, but the definition of art, and its moral and intrinsic value in our lives. Anne Sheppard divides her work (...) into two parts: In the first, she summarizes the major theories defining art and beauty; in the second, she explores the nature of aesthetic evaluation and appreciation. As Sheppard explains, there are three main approaches to defining art, all focused on what art objects share. One proposes that all art imitates something in life, another that it expresses something (such as anger or ecstasy), still another suggests that all art has formal qualities. There is also a fourth which offers that all art shares the quality of beauty. In the second part, which concentrates on literary art, Sheppard explores such philosophic topics as critical judgment, meaning and truth in literature, and the relationship between art and morals. She raises such questions as whether there is one correct interpretation of a work of art and whether art has a moral effect on its audience and, citing specific examples, explores the views that have been put forth. A wide-ranging, intriguing book, which assumes no formal knowledge on the part of its readers, Aesthetics opens the door to a greater understanding and appreciation of art. (shrink)

© 2015 Elsevier Inc.Postnatal organogenesis occurs in an immune competent environment and is tightly controlled by interplay between positive and negative regulators. Innate immune cells have beneficial roles in postnatal tissue remodeling, but roles for the adaptive immune system are currently unexplored. Here we show that adaptive immune responses participate in the normal postnatal development of a non-lymphoid epithelial tissue. Since the mammary gland is the only organ developing predominantly after birth, we utilized it as a powerful system to study (...) adaptive immune regulation of organogenesis. We found that antigen-mediated interactions between mammary antigen-presenting cells and interferon-γ -producing CD4+ T helper 1 cells participate in MG postnatal organogenesis as negative regulators, locally orchestrating epithelial rearrangement. IFNγ then affects luminal lineage differentiation. This function of adaptive immune responses, regulating normal development, changes the paradigm for studying players of postnatal organogenesis and provides insights into immune surveillance and cancer transformation. Plaks et al. (shrink)

H.B.D. Kettlewell is best known for his pioneering work on the phenomenon of industrial melanism, which began shortly after his appointment in 1951 as a Nuffield Foundation research worker in E.B. Ford's newly formed sub-department of genetics at the University of Oxford. In the years since, a legend has formed around these investigations, one that portrays them as a success story of the 'Oxford School of Ecological Genetics', emphasizes Ford's intellectual contribution, and minimizes reference to assistance provided by others. The (...) following essay reviews the important influence Ford, E.A. Cockayne, and P.M. Sheppard played in Kettlewell's research, leading up to his most famous experiments in 1953. It documents several reasons for doubting that Ford was as intellectually involved in the design of these investigations as he has previously been portrayed. It clarifies Kettlewell's intellectual contribution to the investigations for which he is famous, as well as the pivotal roles Cockayne and Sheppard played in the design, execution and interpretation of these investigations. (shrink)

In this article, the authors highlight connections between research on Two Spirit Native Americans and standard social studies curriculum. Two Spirit is a Pan-Indian term describing Native Americans who believe they embody both masculine and feminine characteristics/traits in one physical body. Findingsfrom this research expand the field's conception of multiple perspectives and diversity, while creating opportunities for nuanced understandings of genderexpression and gender that go beyond the male/female dichotomy currently accepted as the norm. The authors utilize historical research and a (...) semi-structured,in-depth interview with a current Ojibwe leader to better understand and theorize Native Americans' acceptance of diverse ways of being. The authors conclude that modern-day social studies teachers and students have much to learn from this traditional Native worldview. Specifically, the authors believe that encouraging students to adopt more inclusive perspectives on gender expression and to recognize the plausibility of multiple genders may lead to more advanced, social learning. Combined with reinforcement from responsible adults at school, this recognition would lessen a variety of present-day social ills, including the incidence of teen suicide caused by homophobia. (shrink)

Interviewed by Christian Sheppard about Richard Kearney’s book The God Who May Be (2001), and speaking also of Kearney’s On Stories (2002) and Strangers, Gods and Monsters (2002), David Tracy remarks on Kearney’s development of the possible as a major philosophical and theological category. Showing the importance of the idea of the infinite, he speaks of the need for a hermeneutical moment to follow the initial encounter, and of a call for general criteria of judgment of the Other. He (...) discusses, too, the dangers and the rewards of doing both theology and philosophy at the same time. To him the category of the Impossible enters into the possible and is not only positive but desired. In a conversation that ranges widely - Derrida and Levinas, Jean-Luc Marion, Angelus Silesius, Kierkegaard, Nicholas of Cusa, Heidegger and Ricoeur, and, in the call for plurality, William James - the two speakers discuss both poetic sensibility and the call for justice. Reflecting on fragmentation, Tracy speaks of the need to focus on suffering and the importance of attaining a sense of ‘the entire story, all of the metaphors’. (shrink)

Carceral spaces such as prisons are designed to restrict freedoms and keep inhabitants confined and under surveillance through various mechanisms. As a result, prisons are spaces where movement is restricted through confinement, while prisoners’ ability to move is conflated with freedom. We aim to move beyond this dichotomy and consider a complex rethinking of the body in criminological theory and practice through dance in carceral space. In doing so, we explore under what conditions movement represents agentic practices. Understanding these nuances (...) requires an interrogation of prisoner agency, including prisoners’ subtle maneuverability of power dynamics within the prison. We explore these dynamics using feminist and arts-based methods, specifically dance workshops delivered to twenty participants incarcerated in a Canadian provincial women’s prison. We find that movement and expression in prison may create moments of agentic freedom for incarcerated women under certain conditions. We argue that more nuanced understandings of incarcerated women’s agency can be found in their daily negotiations of time and space, and movement can provide numerous meanings. Our findings suggest arts-based approaches within prison environments create opportunities for women to express their identity and sexuality through movement in ways otherwise not permitted in prison. For many incarcerated women in this study, this sense of freedom may be associated with the ability to focus and take care of themselves while confined. (shrink)

Scholars and professional organizations in bioethics describe various approaches to “quality assessment” in clinical ethics. Although much of this work represents significant contributions to the literature, it is not clear that there is a robust and shared understanding of what constitutes “quality” in clinical ethics, what activities should be measured when tracking clinical ethics work, and what metrics should be used when measuring those activities. Further, even the most robust quality assessment efforts to date are idiosyncratic, in that they represent (...) evaluation of single activities or domains of clinical ethics activities, or a range of activities at a single hospital or healthcare system. Countering this trend, in this article we propose a framework for moving beyond our current ways of understanding clinical ethics quality, toward comprehensive quality assessment. We first describe a way to conceptualize quality assessment as a process of measuring disparate, isolated work activities; then, we describe quality assessment in terms of tracking interconnected work activities holistically, across different levels of assessment. We conclude by inviting future efforts in quality improvement to adopt a comprehensive approach to quality assessment into their improvement practices, and offer recommendations for how the field might move in this direction. (shrink)

In this important study D. M. Armstrong offers a comprehensive system of analytical metaphysics that synthesises but also develops his thinking over the last twenty years. Armstrong's analysis, which acknowledges the 'logical atomism' of Russell and Wittgenstein, makes facts the fundamental constituents of the world, examining properties, relations, numbers, classes, possibility and necessity, dispositions, causes and laws. All these, it is argued, find their place and can be understood inside a scheme of states of affairs. This is a comprehensive and (...) rigorously this-worldly account of the most general features of reality, argued from a distinctive philosophical perspective, and it will appeal to a wide readership in analytical philosophy. (shrink)

In this Matters Arising article, we outline how the recent article “The impact on patients of objections by institutions to assisted dying: a qualitative study of family caregivers’ perceptions” (White et al., 2023 Mar 13;24(1):22) informed Voluntary Assisted Dying (VAD) implementation in our large Australian public health setting, where objections do not emanate from, but within, the institution. In reporting the harms to patients and caregivers created by institutional objection, White et al. provide an evidenced-based road map for potential potholes (...) or risks associated with VAD implementation. We discuss the complexities emerging from the diverse views of health professionals and the ethical tensions arising from such, especially within certain specialties, and how we developed systemic strategies that support patients, caregivers and staff alike. We highlighted the need to shift from “Do you support VAD?“ to “How can we support you as healthcare professionals to integrate VAD into your practice, in a way that complies with the legislation, meets the needs of patients and caregivers, and feels safe and does not compromise your moral stance?“. (shrink)

This anthology of philosophical texts by Greek and Roman authors brings together works from the late fifth century BC to the sixth century AD that comment on major aesthetic issues such as the perception of beauty and harmony in music and the visual arts, structure and style in literature, and aesthetic judgement. It includes important texts by Plato and Aristotle on the status and the role of the arts in society and in education, and Longinus' reflections on the sublime in (...) literature, in addition to less well-known writings by Philodemus, Cicero, Seneca, Plotinus, Augustine and Proclus. Most of the texts have been newly translated for this volume, and some are available in English for the first time. A detailed introduction traces the development of classical aesthetics from its roots in Platonism and Aristotelianism to its ultimate form in late Antiquity. (shrink)

The metabolic requirements of differentiated neurons are significantly different from that of neuronal precursor and neural stem cells. While a re‐programming of metabolism is tightly coupled to the neuronal differentiation process, whether shifts in mitochondrial mass, glycolysis, and oxidative phosphorylation are required (or merely consequential) in differentiation is not yet certain. In addition to providing more energy, enhanced metabolism facilitates differentiation by supporting increased neurotransmitter signaling and underpinning epigenetic regulation of gene expression. Both epidemiological and animal studies demonstrate that micronutrients (...) (MNs) significantly influence many aspects of neonatal brain development, particularly neural migration and survival, neurite outgrowth, and process maturation. Here we review recent insights into the importance of metabolic reprogramming in neuronal differentiation, before considering evidence that micronutrient signaling may be key to regulating these processes. (shrink)

Humanity needs a way to pool scientific community opinion quickly and efficiently on a given statement of interest. This should be on a very large scale, such that one can have confidence that the result reflects international scientific opinion. For this pilot project (2022-23), we developed tailored architecture in the form of a novel polling platform, to survey a network of scientists at 30 academic institutions around the world. Personal, one-to-one emails were sent to all relevant scientists at those institutions, (...) asking them for their position on our pilot statement, "Science has put it beyond reasonable doubt that COVID-19 is caused by a virus." Scientists answered by clicking a URL embedded in the email, and confirming their response on a 5-point Likert scale. Voting was anonymous, with the token linking the scientist to their vote being destroyed upon voting, and their response logged against the demographics of scientific field of expertise (broadly construed) and institution for subsequent data analysis. (shrink)

As doctoral students from New Zealand and Australia, advised by supervision teams with a diversity of critical realist experience from limited to none, we came independently to the 2018 Critical Re...

As doctoral students from New Zealand and Australia, advised by supervision teams with a diversity of critical realist experience from limited to none, we came independently to the 2018 Critical Re...

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 8.2 (2003) 132-139 [Access article in PDF] Environmentalism: A Global History, by Ramachandra Guha. New York: Longman, 161 pp, includes Bibliographic Essay and Index. Softcover, ISBN 0-321-01169-4. This short but wide-ranging book is a global survey of the history of environmental thought by one of the people most responsible for broadening environmental discussions to include recognition of post-colonial societies. The overall goal of this introductory (...) textbook is to explain multiple environmental discourses from Brazil, the United States, China, India, the Soviet Union, and Africa, and then to situate them as complimentary components of a global socially oriented environmental discursive framework.With that said, it is always difficult to evaluate an introductory textbook. In this case, much of what is covered represents well-worn ground for the environmental scholar. The thesis that emerges is less about a new set of environmental proposals and more about how we ought to understand the history of ideas that informs the development of policy and what ideas ought to be taught in the classroom. Since this book is designed as a textbook, much of my commentary stems from a consideration of how it might work in the classroom. [End Page 132]As an educator regularly teaching courses in environmental thought, ethics, planning, and policy, I have often wondered why so few texts exist on the global history of environmental thought. Guha's work represents an attempt to bridge this gap in the literature. Despite Guha's admirable intentions, I am hesitant to endorse this work as an introductory textbook on the global history of environmental thought for one important reason: Guha's methodology leads to the omission of important components of the global history of environmental thought. From the outset, it is important to acknowledge the difficulty of this type of project. The very title of this work signals perhaps an impossible project, given the 145 pages of text set aside for the task. Guha does cover a number of subjects well, and some are welcome additions to the discussion of the history of environmental thought. Overall though, the topics not covered work to neutralize what is accomplished by the topics that are covered. Consider first what Guha does include.The book is divided into two parts, each focusing on a wave of environmental thought. In the first part, there are four chapters and an afterword. In the initial chapter, Guha argues that a more social and international environmentalism can be a spur to "human reflection and human action," and not just a "scientific study of the state of nature or a balance sheet of the impact of human beings on the earth" (p. 3). While it is common to divide the environmental movement into waves (usually three or four), Guha chooses to delineate only one major shift and thus only two waves of environmentalism. The first wave is comprised of what Guha calls a "period of pioneering and prophecy" and an initial reaction to industrialization; the second wave is comprised of the more socially oriented responses that have emerged in recent decades (p. 3). There are good reasons for delineating more waves, but Guha's project is generally well-served by the two-wave distinction.Guha divides the first wave into three varieties distinguished by their different guiding ideologies—back-to-the-land, scientific conservation, wilderness idea—which are treated respectively in chapters two, three, and four. What I found most compelling about Guha's varieties are some of the figures he chose to include. For example, in chapter two Guha offers a treatment of the back-to-the-land ideology that concurrently condemned excessive industrialization and espoused a commitment to agrarian and pastoral values. From William Wordsworth, William Blake, John Clare, Edward Carpenter, Henry David Thoreau, John Ruskin, Edward Carpenter, [End Page 133] Henry David Thoreau, William Morris, and Octavia Hill, to Gandhi and the Nazis, Guha's range here is impressive. While I do have reservations about how convincing it is to link Wordsworth, Ruskin, and Gandhi according to a largely generic and nondescript agrarian ideal that he claims... (shrink)

To understand why autistic people are misperceived in the way Jaswal & Akhtar suggest, we should embrace concepts like the “double empathy problem” and camouflaging and recognize the negative consequences these have for mental health in autism. Moreover, we need to value expertise from experience so that autistic people have a voice and indeed a stake in research into autism.

ABSTRACT As doctoral students from New Zealand and Australia, advised by supervision teams with a diversity of critical realist experience from limited to none, we came independently to the 2018 Critical Realism conference – primed to seek increased understanding, confidence, motivation, and reassurance. We certainly found these things from the pre-conference, presentations, and individuals within the critical realist community. We also found each other, and a virtual writing group was born. This article is a description of what we did, why, (...) and the outcomes we experienced over the final two years completing our theses. It identifies the structures, contexts, motivations, and mechanisms from which our emotional, critical realist and writing-related outcomes emerged. We outline the roles of serendipitous timing, culture, different disciplinary approaches, administrative structures, and types of interactions on the social learning we developed. We anchor our discussion in recent theoretical literature about the role of writing groups in doctoral education. (shrink)

Drawing on feminist and sociocultural theories of emotion that focus on the social, political, and dynamic nature of emotions in history teachers’ pedagogical decision-making, this article presents findings from the analysis of interviews with two white teachers on the role of emotions in their teaching of history in comprehensive, urban high schools. While the teachers perceived that students’ emotional connection to historical content was a necessary step in learning history, each teacher negotiated different emotional rules in their classrooms, creating unique (...) learning experiences for their students. This study demonstrates the significance of emotions in history teaching, providing examples of the complexity of how teachers navigate dominant discourses about students and education and their own personal goals when it comes to teaching about the past. (shrink)

A comprehensive introduction to the ways in which meaning is conveyed in language. Alan Cruse covers semantic matters, but also deals with topics that are usually considered to fall under pragmatics. A major aim is to highlight the richness and subtlety of meaning phenomena, rather than to expound any particular theory. Rich in examples and exercises, Meaning in Language provides an invaluable descriptive approach to this area of linguistics for undergraduates and postgraduates alike.

Authors philosophical notes on life, conduct of life from the perspective of a life.

A wealth of research suggests the importance of classroom discussion of controversial issues for adequately preparing students for participation in democratic life. Teachers, and the larger public, however, still shy away from such discussion. Much of the current research seeking to remedy this state of affairs focuses exclusively on developing knowledge and skills. While important, this ignores significant ways in which students? beliefs about the concept or nature of controversy itself might affect such discussions and potentially, the sort of citizen (...) that educators are fostering. We argue that examining the concept of ?controversy? is central to conducting such discussions and propose a framework of four crucial virtues or habits of mind that can be developed through such an examination. We illustrate how these four habits of mind are essential for establishing classroom ?counterpublics? that aim to develop more justice-oriented democratic citizens. (shrink)

This article explores the social frameworks guiding expert and nonexpert perspectives on medicines safety in the U.K. Scientific experts from the Committee on the Safety of Medicines and the Medicines Commission were interviewed, and three nonexpertgroups, including patients and health professionals, were studied by the administration of questionnaires and focused group discussions. The research examined to what extent these groups subscribed to technocratic or democratic approaches to medicines regula tion and how this might be related to values toward technological risk. (...) The results reveal that there is substantial divergence between expert and nonexpert perspectives on medicines regulation, and that this derives as much from value differences as from any informational deficits. However, there seems to be some scope for shared values between some experts and some nonexperts, especially as regards state secrecy. The article concludes by discussing how those values could be used to foster a new "social contract of expertise" in which scientists are more democratically accountable and patients take more responsibility in governing medical risks. (shrink)

Theurgy, the religious magic practised by the later Neoplatonists, has been commonly regarded as the point at which Neoplatonism degenerates into magic, superstition and irrationalism.1 A superficial glance at the ancient lives of the Neoplatonists, and in particular at Eunapius’ Lives of the Sophists, reveals a group of people interested in animating statues, favoured with visions of gods and demons, and skilled in rain-making. But when we look more closely at the works of the Neoplatonists themselves, rather than the stories (...) biographers tell about them, we find a considerable diversity of attitudes towards theurgy and a number of attempts to fit theurgy into their philosophical system. (shrink)

This is the first book to consider the increasing importance of Jean-Luc Nancy's work, which has influenced key thinkers such as Jacques Derrida. All his major works have been translated into English, yet until now little has been made available on his place in contemporary philosophy. By showing how he situates his work in a contemporary context - the collapse of communism, the Gulf War, and the former Yugoslavia - this outstanding collection reveals how Nancy's engagement with Hegel, Marx, Nietzsche, (...) Heidegger and Derrida makes him one of the key contemporary continental philosophers. Providing new perspectives on the issues of sense, art and community, these essays make it impossible to approach philosophy without reference to the work Jean-Luc Nancy. (shrink)