This is one of the most significant and serious treatments of the modern roots of the New Age in print.

The human tumour suppressor protein p53 is critical for regulation of the cell cycle on genotoxic insult. When DNA is damaged by radiation, chemicals or viral infection, cells respond rapidly by arresting the cell cycle. A G1 arrest requires the activity of wild‐type p53, as it is not observed in cells lacking functionally wild‐type protein, and at least some component of S phase and G2/M arrests is also thought to be p53‐dependent. p53 functions as a transcription factor which binds specific (...) DNA sequences, and recently major downstream targets have been identified, including p21Cip1 an inhibitor of the cell cycle kinases that also blocks the replicative but not the repair function of DNA polymerase δ auxiliary factor, PCNA. Current interest focuses on developing novel cancer therapies based on our knowledge of the activity of p53 and p21Cip1 in the cell cycle. (shrink)

Experience, God, and theology -- The nature of revelation -- The activity of faith.

One of the pleasures available from Hollywood movies comes from the way they set up at least one character for us to identify with and live vicariously through for a couple of hours. Suspense thrillers ask us to ally ourselves with the protagonist and then get our pleasure, a bit perversely perhaps, from the fact that we cannot be active in that role. No matter how painfully we might squirm at the sights and sounds of the story onscreen, we cannot (...) affect the preset outcome of the filmed events. Most of the time, however, we know we are safe in our helpless position because the protagonist will triumph by the film�s end without our assistance. At worst we can come away from this experience with a na�ve or cynical catharsis about things "turning out okay" despite the feelings of disconnection and powerlessness that many of us experience in the world outside the theater. If one�s lack of agency is more physical than mental/emotional, then this experience might provide genuine psychic relief from that condition. Better still, for those of us with our agency more or less intact both physically and mentally, the path the protagonist follows to his or her happy ending can provide us with insight into changing our own lives. (shrink)