This systematic review identifies and critically evaluates instruments that have been developed to measure clinical trial informed consent comprehension in non-cognitively-impaired adults.Literature searches were carried out on Medline (Ovid), PsycInfo, CINHAL, ERIC, ScienceDirect, and Cochrane Library for English language articles published between January 1980 and September 2008. Instruments were excluded if they focused on consent onto paediatric trials, the construct under study was primarily capacity or competency, or the instrument was developed specifically for psychiatric or cognitively-impaired populations. Instruments selected (...) for review were evaluated against the following criteria: (1) method of item generation; (2) type and format of test items; (3) administration and interpretation of test results; and (4) psychometric properties.Three instruments met our defined inclusion criteria: the Deaconess Informed Consent Comprehension Test (DICCT), the Quality of Informed Consent (QuIC) questionnaire and the Brief Informed Consent Protocol (BICEP). Each instrument varied in terms of content measured. Significantly, these are the first standardized instruments developed to assess comprehension in non-cognitively-impaired adults. Yet, each instrument had its own set of limitations such as the lack of generalizability and the absence of details pertaining to how test results should be used to guide clinical decision-making.Standardized clinical trial informed consent comprehension assessments have been developed to identify gaps in research participants' understanding and ensure that respect for patient autonomy is satisfied. (shrink)

Frank Plumpton Ramsey was born in February 1903, and he died in January 1930—just before his 27th birthday. In his short life he produced an extraordinary amount of profound and original work in economics, mathematics and logic as well as in philosophy: work which in all these fields is still, over sixty years on, extremely influential.

My 1998: 78–81 contains an argument against tensed facts, like the fact that it’s raining now, which exist at some times like 1 January 2010 and not others. ‘Facts’ here means truthmakers, not facts in the trivial sense defined by the equivalence principle EP: For all P, P is a fact iff the proposition ‘P’ is true, in which no one can deny the existence of tensed facts. The argument, which I’ll call TA, may be summarized as follows, where (...) a B-theory of time is one that says there are not, and an A-theory one that says there are, tensed truthmakers. B- theory: Any tensed ‘P’ is made true at any time t by the tenseless fact P-at- t. So: ‘P’ has as many truthmakers as there are times. A-theory: ‘P’ is made true by the tensed fact P, which exists at some but not all t. So: ‘P’ has only one truthmaker, P. So: P makes all tokens of ‘P’ true now. So: P makes tokens of ‘P’ at times when P didn’t exist true now, which is absurd. TA: So: P only makes present tokens of ‘P’ true. So: tokens of ‘P’ at any time t are true iff P exists at t, i.e. ‘P’ is made true at any time t by the tenseless fact P-at- t. So: there are no tensed facts. Max Creswell and Adriane Rini have now produced a modal analogue of TA, which I’ll call MA, whose conclusion is that there are no contingent facts, like the fact that I live in Cambridge, and which may be summarized as follows: Modal realism: Any contingent ‘P’ is made true in any world …. (shrink)

What happened in the aftermath of Caligula's assassination in January A.d. 41 in relation to the client kings of the period has been the subject of a stimulating note by A. A. Barrett. He has argued that a rescission of Caligula's acta invalidated the legal position of the client kings appointed by Caligula, and that Claudius’ regularising of their position has been misunderstood by the ancient literary sources and has given rise to several apparent inconsistencies in their accounts.

One of six commentaries on “Obesity: Chasing an Elusive Epidemic,” by Daniel Callahan, from the January‐February 2013 issue.

In the United States, screening the urine of employees or job applicants for the presence of drugs has become commonplace. A survey of 794 large- and mediumsized companies, conducted by the American Management Association in January 1994, found that 87 percent of them now test job applicants for drug use. In 1987, a similar survey found that 22 percent screened job applicants. Federally mandated drug testing programs with random testing requirements affect millions of workers in the transportation industry, the (...) nuclear power industry, and the United States civil and military services.As some of these programs pass their fifth anniversary since being instituted, it is important to assess the forces that led to their creation. Whether or not these programs are considered successful depends on what one expects to achieve by such widespread testing. (shrink)

In the United States, screening the urine of employees or job applicants for the presence of drugs has become commonplace. A survey of 794 large- and mediumsized companies, conducted by the American Management Association in January 1994, found that 87 percent of them now test job applicants for drug use. In 1987, a similar survey found that 22 percent screened job applicants. Federally mandated drug testing programs with random testing requirements affect millions of workers in the transportation industry, the (...) nuclear power industry, and the United States civil and military services.As some of these programs pass their fifth anniversary since being instituted, it is important to assess the forces that led to their creation. Whether or not these programs are considered successful depends on what one expects to achieve by such widespread testing. (shrink)

_The Ethics and Religious Philosophy of Etty Hillesum_ offers a comprehensive account of international scholarship on the life, works and vision of the Dutch Jewish writer Etty Hillesum, and her struggle to come to terms with her personal life in the context of the Holocaust.

Contributed papers on concept of False and Indivisibles (Philosophy) in Hindu philosophy presented at Seminar organized by Department of Advaita Vedanta, Rāṣṭrīyasaṃskr̥tavidyāpīṭham, Tirupati from December 31, 2005 to January 01, 2006).

Frank Plumpton Ramsey was born in February 1903, and he died in January 1930—just before his 27th birthday. In his short life he produced an extraordinary amount of profound and original work in economics, mathematics and logic as well as in philosophy: work which in all these fields is still, over sixty years on, extremely influential.

In January 1990, the Parti Réformateur Libéral inaugurated a brand new management, called "bicephalism ": instead of the traditional presidentialsystem, one "ticket" with a president and a vice-president was commissioned to ensure the leadership of the party.The bicephalism was only the result of a tricky internal compromise, stemming from the discontent following the return of the party in the opposition and strengthened after the defeat at the European polls.The "two-headed" system wanted to restore the credibility and to reinforce the (...) cohesion of the PRL. In fact, this genuine political "curiosity" mainly revealed the structural and ideological deficiency which made its coming possible. lts ultimate defeat - at the 24 November1991 polls - caused itsfalling down.The bicephalism was bound to an identity problem of the french Belgian liberalism but also some features of the experience refer to a more general crisis of the values carried by the old traditional political movements. (shrink)

sirIn the January 4 issue of the New England Journal of Medicine three articles appeared on the unapproved use of Misoprostol , which raise an interesting ethical question. The synthetic prostaglandin analogue, Misoprostol, has been successfully used by obstetricians and gynaecologists for a number of years for the induction of a medical abortion in the first or second trimester, for the induction of labour, and for the prevention of postpartum haemorrhages.1 Strangely enough the pharmaceutical company which produces and markets (...) the drug, Searle, …. (shrink)

The public revelation in 2003 that medical students perform intimate examinations without patient consent has engendered much debate in the press and scientific journals. Using this case as a springboard for discussion, I will argue that medical schools should encourage students to raise their ethical concerns and call for a change of policy making it easier for students to do so. I will also address the question of medical students’ moral obligations towards their patients, and conclude that medical students ought (...) to express their discontent when faced with unethical practices or attitudes.In early January 2003, a study appeared in the British Medical Journal revealing that nearly a quarter of rectal and vaginal examinations on anaesthetised patients were performed by medical students without patient consent.1 Although the study did not generate the firestorm of controversy many expected, it engendered much discussion on ethical issues surrounding informed consent and patient autonomy, as well as stressing the need for greater ethics training for medical students. As an ethical problem, however, the case of intimate examinations is, to my mind, relatively uninteresting. If we agree that it is wrong for doctors to perform a vaginal examination on a conscious person without their consent, then it follows that it will still be …. (shrink)

(2002). Philosophy of Science 72 (January), 198-208.

The primary objective was to review pediatric ethics consultations at a large academic health center over a nine year period, assessing demographics, ethical issues, and consultant intervention. The secondary objective was to describe the evolution of PECs at our institution. This was a retrospective review of Consultation Summary Sheets compiled for PECs at our Academic Health Center between January 2008 and April 2017. There were 165 PECs reviewed during the study period. Most consult requests came from the inpatient setting, (...) with the Pediatric and Neonatal Intensive Care Units being the highest utilizers. Consultation utilization increased over the study period. The most common patient age was less than one year. Physicians were most likely to request consultation. Patient Best Interest, Withholding/Withdrawing of Life Sustaining Therapy, and Provider Moral Distress were ethical issues most commonly identified by the consultants. Making recommendations was the most common consultant intervention. The ethics consultation process evolved over time from informal provider discussions, to a hospital infant care review committee, to a pediatric only consultation service, to a combined adult/pediatric consultation service, with variable levels of salary support for consultants. Ethics consultation requests are growing at our institution. Similarities in identified ethical issues exist between our findings and existing literature, however meaningful comparisons remains elusive secondary to variability in approaches to investigation and reporting. A combined paid/volunteer/trainee ethics consultation service model appears sustainable and real time ethics consultation is feasible using this approach. (shrink)

Background: Decisions of patients, families, and health care providers about medical care at the end of life depend on many factors, including the societal culture. A pan-European study was conducted to determine the frequency and types of end of life practices in European intensive care units , including those in Israel. Several results of the Israeli subsample were different to those of the overall sample.Objective: The objective of this article was to explore these differences and provide a possible explanation based (...) on the impact of culture on end of life decision making.Method: All adult patients admitted consecutively to three Israeli ICUs who died or underwent any limitation of life saving interventions between 1 January 1999 and 30 June 2000 were studied prospectively . These patients were compared with a similar sample taken from the larger study carried out in 37 European ICUs. Patients were followed until discharge, death, or 2 months from the decision to limit therapy. End of life decisions were prospectively organised into one of five mutually exclusive categories: cardiopulmonary resuscitation , brain death, withholding treatment, withdrawing treatment, and active shortening of the dying process . The data also included patient characteristics , specific therapies limited, and the method of SDP.Results: The majority of patients had treatment withheld, none underwent SDP, 62 received CPR , 31 had brain death , and 18 underwent withdrawal of treatment . The primary reason given for limiting treatment was that the patient was unresponsive to therapy . End of life discussions were held with 132 families , the vast majority of which revolved around withholding treatment and the remainder concerned withdrawing treatment .There was a statistically significant association between the type of end of life decision and region—that is, the northern region of Europe, the central region, the southern region, and Israel.Conclusions: Regional culture plays an important part in end of life decision making. Differences relating to end of life decision making exist between regions and these differences can often be attributed to cultural factors. Such cultures not only affect patients and their families but also the health care workers who make and carry out such decisions. (shrink)

These remarkable memoirs were published first in Russian in 1953 and were translated into French in 1964. At last they are available in English in a very readable translation. The author was on friendly terms with Lenin in Geneva from January to June 1904, a period of great stress in Lenin's life when he was writing One Step Forward, Two Steps Back. The human, all too human, side of the great historical figure is vividly and sympathetically portrayed. Lenin was (...) fascinated with violence, but always kept himself at a safe distance from it. His vanity and pride made him incapable of frankness. His ignorance of Shakespeare, Byron, Molière, Schiller, and his enthusiasm for Chernyshevsky's What is to be Done? reflect his intellectual narrowness. He was incapable of grasping a fresh idea, or of respecting any person who disagreed with his convictions. No tactics were too low in settling personal scores. Among his more appealing characteristics one might mention his firm faith in the Russian Revolution, his energy and dedication to his work, his love of music, nature, and physical activity. But the book contains much more than a new and clear-headed insight into Lenin's intellectual development and personality. There are vivid descriptions of many leaders of the Revolution, of the oppressive atmosphere of life in exile, of the discrepancy between hopes and reality. The personality of the author, his fairness, sincerity, and honesty, are stamped on the whole book making it an entertaining and rewarding experience.--T. D. Z. (shrink)

Contributed papers on concept of Avidyā and Mokṣa in Hindu philosophy presented at Seminar organized by Department of Advaita Vedanta, Rāṣṭrīyasaṃskr̥tavidyāpīṭham, Tirupati from December 31, 2005 to January 01, 2006).

The British Museum, based in Montague House, Bloomsbury, opened its doors on 15 January 1759, as the world's first state-owned public museum. The Museum's collection mostly originated from Sir Hans Sloane, whose vast holdings were purchased by Parliament shortly after his death. The largest component of this collection was objects of natural history, including a herbarium made up of 265 bound volumes, many of which were classified according to the late seventeenth-century system of John Ray. The 1750s saw the (...) emergence of Linnaean binomial nomenclature, following the publication of Carl Linnaeus'Species Plantarum andSystema Naturae. In order to adopt this new system for their collections, the Trustees of the British Museum chose to employ the Swedish naturalist and former student of Linnaeus, Daniel Solander to reclassify the collection. Solander was ordered to devise a new system for classifying and cataloguing Sloane's natural history collection, which would allow both Linnaeans and those who followed earlier systems to access it. Solander's work was essential for allowing the British Museum to realize its aim of becoming a public centre of learning, adapting the collection to reflect the diversity of classificatory practices which were existent by the 1760s. This task engaged Solander until 1768, when he received an offer from Joseph Banks to accompany him on HMSEndeavourto the Pacific. (shrink)

This book is a methodological guide for the emerging, interdisciplinary science of virtue traits and their value. The authors situate this emerging empirical field in the history of psychology, critically survey existing work, defend the scientific validity of virtue science, and develop a general model that can guide, unify, and catalyze future research. In addition, chapters discuss how philosophy and philosophers can contribute to empirical inquiry and how a mature science of virtue could inform moral philosophy. The book is co-authored (...) by two psychologists and a philosopher who pursued joint empirical work on fairness and then began to discuss larger methodological issues raised by that collaboration. -/- o Expected publication date: January 31, 2024 o Paperback ISBN: 1108747981. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd Reviews 179 THE EARLY “IRON CURTAIN” Michael D. Stevenson Schulich School of Business, York U. / Russell Research Centre, McMaster U. Toronto, on m3j 1p3 / Hamilton, on l8s 4l6, Canada [email protected] Patrick Wright. Iron Curtain: from Stage to Cold War. Oxford: Oxford U. P., 2007. Pp. xvii, 488. isbn 978-0-19-923150-8. £18.99 (hb); £12.99 (pb). In his famous Westminster College (...) address on 5 March 1946 in Fulton, Missouri, Winston Churchill Wred one of the opening salvos of the Cold War by proclaiming that from “Stettin in the Baltic to Trieste in the Adriatic an iron curtain” had been lowered across Europe. Patrick Wright’s intriguing and provocative book does not examine the phrase “iron curtain” in its popular Cold War context. Instead, he maintains that many characteristics of this metaphor, “including the pronounced sense of theatricality it would bring to international politics, were inherited from the period before the Second World War” (p. 18). Wright divides Iron Curtain into two primary chronological sections, the Wrst covering the period from 1914 to 1920. An iron curtain originally referred to the steel safety screen that descended in English theatres, beginning in the lateeighteenth century, to separate the audience from the often catastrophic Wres that broke out on the stage. The phrase entered the lexicon of international relations in January 1915 when British author and paciWst Violet Page (writing under the pseudonym Vernon Lee) published an article lamenting that “War’s cruelties and recriminations, War’s monstrous iron curtain” (p. 80) had alienated European nations such as England and Germany sharing a common cultural heritage. But the barrier quickly moved east in the aftermath of the 1917 Russian Revolution and “took the form not just of exaggerated political rhetoric, but of an economic blockade enforced by naval power” (p. 171), as the Allies sought to contain the infection of Bolshevism. Wright devotes most attention in this section to documenting the 1920 visit to Russia by the British delegation jointly sponsored by the Trades Union Congress and the Labour Party, which sought to penetrate the dense fog of Allied anti-Bolshevik propaganda and validate the delegation members’ own preconceived views about the nascent socialist utopia in Russia. British delegates witnessed images both of progress carefully stagemanaged by their hosts and of terrible economic dislocation and poverty caused by the Allied blockade and the civil war, which allowed the majority of them to return home to lavish praise on the Soviet experiment that would, in their minds, inevitably fulWl its potential once the Bolshevik government became stable. February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd 180 Reviews 1 “The Future of Europe”, European AVairsz 1, no. 1 (April 1949): 3. The second section of Wright’s book examines Western reports of life behind the iron curtain between 1920 and 1939. Here, the author focuses heavily on the theatrical nature of Soviet attempts to create modern-day Potemkin villages that werez—zwith a limited number of exceptionsz—zaccepted as reality by an endless parade of left-wing visitors. A second British Trades Union Congress delegation in 1924, for example, received a dramatically embellished picture of Soviet economic progress that included a train journey past a long-abandoned factory belching smoke created by burning wet straw frantically provided by Russian peasants; the resulting report of the delegation “repeatedly collapsed into the most abject conformity with the Soviet view of reality” (p. 245). The most tragic examples of Western visitors’ blindness to the truth occurred during the 1930s famine deliberately induced by Stalin, and Wright exposes a wide cast of characters who adopted a blinkered view of conditions in the ussr. Among intellectuals, Wright documents the 1931 visit of George Bernard Shaw, who cavalierly dismissed reports of widespread food shortages while dining sumptuously in Moscow’s Hotel Metropole. Among journalists, Wright develops the case of Walter Duranty, the New York Timesz correspondent who knuckled under to demands of Soviet censors to produce sanitized accounts denying or ignoring the famine in order to protect his privileged place in that... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Notes on Psychodramatic Treatment of a Person with SchizophreniaJonathan D. Moreno, PhD (bio)I have enjoyed reflecting on Mr. Chapy’s account of work in psychodrama with a patient with schizophrenia.Although at one time many years ago I was interested in phenomenological psychiatry, and especially the writings of Ludwig Binswanger and Medard Boss, I am not an authority on dasein-analysis, so I have nothing to add to the discussion. I should (...) say, however, that my father had little interest in this approach, which was far too abstract for his taste. He proceeded from the standpoint of the theater, of action and enactment. He believed that the drama itself provided the insight.For the purposes of this response, I take it as a given that the patient in question has been accurately diagnosed, although in the description of the scene with his father he does not exhibit the usual symptoms, such as auditory hallucinations. People with schizophrenia often find it difficult to manage the voices they are hearing without substantial preparation for a psychodrama. According to psychodramatic method, one way to prepare them is to externalize the voices, allowing a different therapist to take the role of each one as the protagonist instructs them how to play that role. Chair may be set up so that each “voice,” personified by an auxiliary ego, can sit in each chair in an array. This preparation may require a number of sessions. If the scene is to be enacted with a significant other, like the father in this instance, the patient may not be able to warm up to a direct encounter, especially with all the different voices competing for his internal attention. So he may be directed to observe each voice in the encounter with his father, preferably played by a therapist of his choosing and trained for the role, usually by giving the father-player certain lines so that they can learn something about the father and the way he addresses his son.Or consider the patient whose illness manifests itself as delusions, often of a megalomaniac character. They may be a messiah, for example, or the rightful heir of a royal line whose identity is being suppressed by governmental forces. The patient might be invited to choose key therapists to play the roles of key members of their circle, [End Page 225] enacting critical scenes like the sermon on the mount or speeches to their oppressed followers. In this way the patient’s “act hunger” may be to some degree satiated and have a calming effect on their anxiety and irritation with the frustrating world around them that refuses to accept their “authentic” identity and belief system.In these ways, psychodrama therapy can take advantage of one of the remarkable advantages of this method for such patients, who are generally recalcitrant to talk therapy alone and for whom medication is at best modestly effective. Still, these disorders are among the most challenging for psychotherapists. Although the process of treating them may open up insights into the nature of the human mind, as Chapy has pursued in this paper, we await the neuroscience that can affect the kind of long-term remission they and their families so desperately wish. [End Page 226]Jonathan D. MorenoUniversity of Pennsylvania [email protected] D. Moreno Jonathan D. Moreno is a philosopher and historian who specializes in the intersection of bioethics, culture, science, and national security, and has published seminal works on the history, sociology and politics of biology and medicine. He is an elected member of the National Academy of Medicine.submitted on January 27, 2023Accepted on January 30, 2023Copyright © 2023 Johns Hopkins University Press... (shrink)

A commentary on “Were There ‘Additional Foreseeable Risks’ in the SUPPORT Study?,” by Henry J. Silverman and Didier Dreyfuss; “SUPPORT: Risks, Harms, and Equipoise,” by Robert M. Nelson; “The Controversy over SUPPORT Continues and the Hyperbole Increases,” by Alan R. Fleischman; and “SUPPORT and Comparative Effectiveness Trials: What's at Stake?,” by Lois Shepherd, all in the January‐February 2015 issue.

Bulletin de Philosophie Médiévale, Volume 62, Issue, Page 335-338, January 2020.

Ronald Reagan, in his inaugural address as the Governor of California on January 5th, 1967, poignantly stated the following on the fragility of freedom: -/- "Perhaps you and I have lived too long with this miracle to properly be appreciative. Freedom is a fragile thing and it’s never more than one generation away from extinction. It is not ours by way of inheritance; it must be fought for and defended constantly by each generation, for it comes only once to (...) a people. And those in world history who have known freedom and then lost it have never known it again." -/- These words ring as true today as they did when they were first uttered. And yet, over 55 years later, the majority of countries throughout the world and the majority of people living in them have been quick to relinquish their rights and freedoms under the pretext of “health safety.” Since March 2020, the world has been brought to its knees by what I would argue are unscientific and unethical mandates related to the COVID-19 crisis. These mandates have had a tremendously negative impact on the world economy and the lives of countless individuals. The ‘cure’ that has been offered. (shrink)

This paper proposes an analytical taxonomy of ‘mystery’ based upon what makes a mystery mysterious. I begin by distinguishing mysteries that depend on what we do not know (e.g. detective fiction) from mysteries that depend on what we do know (e.g. religious mysteries). Then I distinguish three possible grounds for the latter type. The third and most provocative ground offers a mathematical analogy for how rational reflection can be appropriate to mystery without compromising its intrinsically mysterious character. I conclude with (...) reflections on the metaphysical presuppositions that this understanding of mystery requires. (Published Online January 15 2007). (shrink)

SUMMARYMachine Translation is now ubiquitous in discussions of translation. The roots of this phenomenon — first publicly unveiled in the so-called ‘Georgetown-IBM Experiment’ on 9 January 1954 — displayed not only the technological utopianism still associated with dreams of a universal computer translator, but was deeply enmeshed in the political pressures of the Cold War and a dominating conception of scientific writing as both the goal of machine translation as well as its method. Machine translation was created, in part, (...) as a solution to a perceived crisis sparked by the massive expansion of Soviet science. Scientific prose was also perceived as linguistically simpler, and so served as the model for how to turn a language into a series of algorithms. This paper follows the rise of the Georgetown program — the largest single program in the world — from 1954 to the collapse of MT in 1964. (shrink)

NCMRD initiated the Women in Management Research Program in January 1988. One of the objectives of the program is to help managers and policy makers deal with issues arising from women's increased participation in managerial and professional jobs backing research to help arrive at solutions to the problems being encountered both by institutions and by women themselves. Significant research funds have been raised from the private sector and ten projects have been funded to date. This article describes the early (...) development of the Program and its research mandate. (shrink)

The American Journal of Bioethics, Volume 12, Issue 1, Page 16-18, January 2012.

Claudian's poem In Rufinum is a historical epic with at least two unusual features: the first book contains many of the standard elements of a formal invective, and the two books were composed and recited some eighteen months apart, since Book One celebrates the death of Rufinus on 27 November 395 as a very recent event, while the preface to Book Two refers explicitly to Stilicho's expedition to Greece in 397. The interval in composition is matched by a gap in (...) content: Book One treats Rufinus' career down to 393, with some forward references to 395, explicitly marked as such, while the narrative of Book Two begins from the death of Theodosius on 17 January 395 and ends with the lynching of Rufinus on 27 November 395. Claudian thus omits any account of Rufinus' activities during the campaign of Theodosius against Eugenius in 394 and the emperor's last months in Italy. Claudian's careful chronological ordering of his material is deliberate, but since it has been obscured in recent discussions of the In Rufinum, it needs to be reinstated. (shrink)

Claudian's poem In Rufinum is a historical epic with at least two unusual features: the first book contains many of the standard elements of a formal invective, and the two books were composed and recited some eighteen months apart, since Book One celebrates the death of Rufinus on 27 November 395 as a very recent event , while the preface to Book Two refers explicitly to Stilicho's expedition to Greece in 397. The interval in composition is matched by a gap (...) in content: Book One treats Rufinus' career down to 393, with some forward references to 395, explicitly marked as such , while the narrative of Book Two begins from the death of Theodosius on 17 January 395 and ends with the lynching of Rufinus on 27 November 395. Claudian thus omits any account of Rufinus' activities during the campaign of Theodosius against Eugenius in 394 and the emperor's last months in Italy. Claudian's careful chronological ordering of his material is deliberate, but since it has been obscured in recent discussions of the In Rufinum, it needs to be reinstated. (shrink)

The following remarks on the aviary simile have been prompted by Professor Hackforth's article in C.Q. January 1938, pp. 27 ff., in which he in turn comments on certain points in Professor Cornford's treatment in his Plato's Theory of Knowledge. Commenting on 199c–d C. suggests that P.'s criticism in that passage might be met by the inclusion in the aviary of ‘complex objects such as the “sum of 7 and 5”.… It is this object that I identify with 11 (...) when I make my false judgement.… False judgement can be explained as the wrong putting together of two pieces of knowledge’—i.e. 11 and ‘the sum of 7 and 5’. C. further suggests that P. has overlooked this possibility because he persists in speaking as if we judged not ‘that the sum of 7 and 5 is 11’ but that ‘12 is 11 ’. H. replies that this criticism of C.'s is not valid because P. understands the knowledge of 11 and 12 to include a knowledge of the various sums that make up these numbers. There could, therefore, be no ‘question of “putting together” such a piece of knowledge as 7 + 5 = 12 with a different piece of knowledge, viz. the knowledge of 12. They are not different pieces; they are the same piece.’. (shrink)

The following remarks on the aviary simile have been prompted by Professor Hackforth's article in C.Q. January 1938, pp. 27 ff., in which he in turn comments on certain points in Professor Cornford's treatment in his Plato's Theory of Knowledge. Commenting on 199c–d C. suggests that P.'s criticism in that passage might be met by the inclusion in the aviary of ‘complex objects such as the “sum of 7 and 5”.… It is this object that I identify with 11 (...) when I make my false judgement.… False judgement can be explained as the wrong putting together of two pieces of knowledge’—i.e. 11 and ‘the sum of 7 and 5’. C. further suggests that P. has overlooked this possibility because he persists in speaking as if we judged not ‘that the sum of 7 and 5 is 11’ but that ‘12 is 11 ’. H. replies that this criticism of C.'s is not valid because P. understands the knowledge of 11 and 12 to include a knowledge of the various sums that make up these numbers. There could, therefore, be no ‘question of “putting together” such a piece of knowledge as 7 + 5 = 12 with a different piece of knowledge, viz. the knowledge of 12. They are not different pieces; they are the same piece.’. (shrink)

Hastings Center Report, Volume 52, Issue 1, Page 21-28, January/February 2022.

BackgroundThe Netherlands is one of the few countries where euthanasia is legal under strict conditions. This study investigates whether Dutch newspaper articles use the term ‘euthanasia’ according to the legal definition and determines what arguments for and against euthanasia they contain.MethodsWe did an electronic search of seven Dutch national newspapers between January 2009 and May 2010 and conducted a content analysis.ResultsOf the 284 articles containing the term ‘euthanasia’, 24% referred to practices outside the scope of the law, mostly relating (...) to the forgoing of life-prolonging treatments and assistance in suicide by others than physicians. Of the articles with euthanasia as the main topic, 36% described euthanasia in the context of a terminally ill patient, 24% for older persons, 16% for persons with dementia, and 9% for persons with a psychiatric disorder. The most frequent arguments for euthanasia included the importance of self-determination and the fact that euthanasia contributes to a good death. The most frequent arguments opposing euthanasia were that suffering should instead be alleviated by better care, that providing euthanasia can be disturbing, and that society should protect the vulnerable.ConclusionsOf the newspaper articles, 24% uses the term ‘euthanasia’ for practices that are outside the scope of the euthanasia law. Typically, the more unusual cases are discussed. This might lead to misunderstandings between citizens and physicians. Despite the Dutch legalisation of euthanasia, the debate about its acceptability and boundaries is ongoing and both sides of the debate are clearly represented. (shrink)

Cognitive Science, Volume 46, Issue 1, January 2022.

Objectives To evaluate whether the requirement of “minimal risk and burden” for paediatric research without direct benefit to the subjects compromises the ability to obtain data necessary for improving paediatric care. To provide evidence-based reflections on the EU recommendation that allows for a higher level of risk. Design and setting Systematic analysis of the approval/rejection decisions made by the Dutch Central Committee on Research involving Human Subjects (CCMO). Review methods The analysis included 165 proposals for paediatric research without direct benefit (...) that were reviewed by the CCMO between January, 2000, and July, 2007. A separate, in-depth analysis of all drug studies included 18 early phase drug studies and nine other drug studies without direct benefit. Results 11 out of 165 studies were definitively rejected because the CCMO did not regard the risk and/or burden to be minimal. In three of these 11 cases (including two early phase drug studies) the requirement of minimal risk and burden was cited as the only reason for rejection. Four other early phase drug studies also involved risks and/or burdens that were not regarded to be minimal but were nevertheless approved. Conclusions The requirement of minimal risk and burden, aiming to protect research subjects, occasionally leads to rejection of protocols. Early phase drug studies relatively often do not comply with the requirement. Committees may find ways to approve important studies that formally should be rejected, but that is not a desirable solution. The regulatory framework should be revised to make such occasional exceptions to the requirement legitimate and transparent. (shrink)

This survey on biotechnology and bioethics was carried out onnational random samples of the public and scientists in November2000-January 2000 throughout Japan, and attendees at theNovartis Life Science Forum held on 29 September, 1999 inTokyo. The sample size was 297, 370, and 74 respectively. Whilethere is better awareness of GMOs in 2000 compared to 1991; thetrend shows an increase in the perceived risks of GMOs followedby growing resistance in Japan. While a majority of personsbelieved genetic engineering would make life (...) better over the nexttwenty years , the proportion of respondents who thoughtgenetic engineering would make life worse over the next twentyyears doubled from 1997 to 2000 .Respondents were asked whether they had heard aboutapplications in several areas and the order of familiarity was: pest-resistant crops, human genes in bacteria, mouseto develop cancer, food and drinks, pigs with human hearts andpre-implantation diagnosis. A divide of opinion can be seen whenthe results on benefit, risk and moral acceptability of applicationsof biotechnology by the public are compared to the forum andscientist samples.A significant change in the acceptance of the public occurred in2000 where only 22% agreed on the moral acceptability of GMfood compared to 41% in 1997. In 2000 fewer people said they arewilling to buy genetically modified fruits that taste bettercompared to 1997 . The results show less public support foruse of gene therapy than 1993 and twice as many scientistsrejected gene therapy than they did in 1991.When asked whom is best placed to regulate modernbiotechnology, the respondents were overwhelmingly in favor ofinternational regulatory bodies, such as the United Nations andthe World Health Organization , rather than national bodies.The comparison between scientists and public is interesting,however the more enthusastic sample were participants from theNovartis Life Science Forum with its mixed occupations. (shrink)

The COVID-19 evolution has forced the massive introduction of homeworking for most employees in the initial stages of the pandemic and then return to work, mainly due to the vaccination campaign. These multiple abrupt adjustment demands in work may be a source of intense stress for office workers with consequences on wellbeing and the quality of life. This long-term prospective study aimed at investigating the effect of adaptation demands on a broad population of employees of a large Italian banking group (...) in the job-related stress framework. We administered a web-based survey to 1,264 participants in Reopening after the first lockdown, from June to October 2020, at 841 subjects in Second Wave, corresponding to the rise of contagions from November 2020 to January 2021, and to 491 individuals in Vaccination Round, which ranged from February to June 2021. We assessed workaholism by using the Dutch Work Addiction Scale, work-family conflicting overlap by using the Work and Family Conflict Scale, and concern for back to work and for HW by specific questions. Higher WAFCS scores characterized Reopening and Vaccination Round while Second Wave had the highest level of concern for HW. Women and younger individuals showed the highest concern for BW, WAFCS, and DUWAS-10 scores regardless of the pandemic stage. HW days per week were related to more heightened concern for BW and lower concern for HW, DUWAS, and WAFCS scores. The number of children was related to lower Concern for BW and higher WAFCS scores in Reopening and Second Wave. Our data showed that massive adjustment demands in work and family routine represented a significant source of stress for employees, regardless of the different pandemic stages. The highest level of fatigue emerged in women and younger subjects. These results shed light on the need for a road map to promote a gradual and structured adjustment for workers and encourage organizations to consider homeworking as a valid stable alternative. (shrink)

This article constitutes excerpts of a videotaped discussion hosted by the New England Journal of Medicine on January 14, 2008, concerning a range of topics on lethal injection prompted by the United States Supreme Court's January 7 oral arguments in Baze v. Rees. Dr. Atul Gawande moderated the roundtable that included two anesthesiologists - Dr. Robert Truog and Dr. David Waisel - as well as law professor Deborah Denno. The discussion focused on the drugs used in lethal injection (...) executions, whether physicians should participate, potential alternatives, and some of the legal parameters of Baze. (shrink)

We are printing, by kind permission of the Law Commission, two sections of the report of the Law Commission on injuries to unborn children. This report was the result of a request to the Law Commission by the Lord Chancellor at the time (Lord Hailsham of Saint Marylebone) to advise on `what the nature and extent of civil liability for antenatal injury should be'. The Law Commission followed its usual practice in such circumstances of consulting various bodies and obtaining expert (...) advice on the subject and then embodying the results in a working paper (Working Paper No. 47 - injuries to unborn children) published on 19 January 1973, which preceded their report (Cmnd 5709). Meanwhile a Royal Commission is considering much wider issues of civil liability for injury (including antenatal injury) but the terms of reference for the Law Commission were much narrower and confined to the position of children injured before birth. In the section relating to the present law the report makes it clear that it is probable that liability under the common law already exists. The Scottish Law Commission has also issued a report (Cmnd 5371). They were given different terms of reference and came to somewhat different conclusions. We are printing from this long report the paragraphs discussing the medical background and the summary of recommendations. As will be evident on reading the paragraphs on the medical background to injuries to the unborn child, events are moving very rapidly, particularly in the study of congenital defects and the effects of drugs but the problems of proof present great difficulty. Other causes of injury to the unborn child are better known to the general public: for example, those following the illness, infection and disease of the mother during pregnancy, injury caused in attempted termination of pregnancy and the risks resulting from the mother's condition. The summary of the recommendations sets out very clearly the legal position of the unborn child, as the Law Commission sees it, arising from injury before birth, the final conclusion being that `legislation is desirable'. These extracts from the report, apart from their intrinsic interest, lead on to the paper by Mr Kennedy and Dr Edwards in which they set out their criticisms of it, and provide quick references to the original document. (shrink)