27 found
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  1. An organizational account of biological functions.Matteo Mossio, Cristian Saborido & Alvaro Moreno - 2009 - British Journal for the Philosophy of Science 60 (4):813-841.
    In this paper, we develop an organizational account that defines biological functions as causal relations subject to closure in living systems, interpreted as the most typical example of organizationally closed and differentiated self-maintaining systems. We argue that this account adequately grounds the teleological and normative dimensions of functions in the current organization of a system, insofar as it provides an explanation for the existence of the function bearer and, at the same time, identifies in a non-arbitrary way the norms that (...)
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  2. Biological Organization and Cross-Generation Functions.Cristian Saborido, Matteo Mossio & Alvaro Moreno - 2011 - British Journal for the Philosophy of Science 62 (3):583-606.
    The organizational account of biological functions interprets functions as contributions of a trait to the maintenance of the organization that, in turn, maintains the trait. As has been recently argued, however, the account seems unable to provide a unified grounding for both intra- and cross-generation functions, since the latter do not contribute to the maintenance of the same organization which produces them. To face this ‘ontological problem’, a splitting account has been proposed, according to which the two kinds of functions (...)
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  3. Disease-mongering through clinical trials.María González-Moreno, Cristian Saborido & David Teira - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 51:11-18.
    Our goal in this paper is to articulate a precise concept of at least a certain kind of disease-mongering, showing how pharmaceutical marketing can commercially exploit certain diseases when their best definition is given through the success of a treatment in a clinical trial. We distinguish two types of disease-mongering according to the way they exploit the definition of the trial population for marketing purposes. We argue that behind these two forms of disease-mongering there are two well-known problems in the (...)
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  4. Health and environment from adaptation to adaptivity: a situated relational account.Laura Menatti, Leonardo Bich & Cristian Saborido - 2022 - History and Philosophy of the Life Sciences 44 (3):1-28.
    The definitions and conceptualizations of health, and the management of healthcare have been challenged by the current global scenarios (e.g., new diseases, new geographical distribution of diseases, effects of climate change on health, etc.) and by the ongoing scholarship in humanities and science. In this paper we question the mainstream definition of health adopted by the WHO—‘a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity’ (WHO in Preamble to the constitution of (...)
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  5.  40
    Is Aging a Disease? The Theoretical Definition of Aging in the Light of the Philosophy of Medicine.Cristian Saborido & Pablo García-Barranquero - 2022 - Journal of Medicine and Philosophy 47 (6):770-783.
    In the philosophical debate on aging, it is common to raise the question of the theoretical definition of aging in terms of its possible characterization as a disease. Understanding aging as a disease seems to imply its medicalization, which has important practical consequences. In this paper, we analyze the question of whether aging is a disease by appealing to the concept of disease in the philosophy of medicine. As a result of this analysis, we argue that a pragmatist approach to (...)
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  6.  35
    Functions, Organization and Etiology: A Reply to Artiga and Martinez.Cristian Saborido & Matteo Mossio - 2016 - Acta Biotheoretica 64 (3):263-275.
    We reply to Artiga and Martinez’s claim according to which the organizational account of cross-generation functions implies a backward looking interpretation of etiology, just as standard etiological theories of function do. We argue that Artiga and Martinez’s claim stems from a fundamental misunderstanding about the notion of “closure”, on which the organizational account relies. In particular, they incorrectly assume that the system, which is relevant for ascribing cross-generation organizational function, is the lineage. In contrast, we recall that organizational closure refers (...)
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  7.  59
    Biological pathology from an organizational perspective.Cristian Saborido & Alvaro Moreno - 2015 - Theoretical Medicine and Bioethics 36 (1):83-95.
    In contrast to the “normativist” view, “naturalist” theorists claim that the concept of health refers to natural or normal states and propose different characterizations of healthy and diseased conditions that are meant to be objectivist and biologically grounded. In this article, we examine the core concept of these naturalist accounts of disease, i.e., the concept of biological malfunction, and develop a new formulation of the notion of malfunction following the recent organizational approach to functions in the philosophy of biology. We (...)
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  8.  34
    Biological Purposes Beyond Natural Selection: Self-Regulation as a Source of Teleology1.Javier González de Prado & Cristian Saborido - forthcoming - Erkenntnis:1-20.
    Selected-effects theories provide the most popular account of biological teleology. According to these theories, the purpose of a trait is to do whatever it was selected for. The vast majority of selected-effects theories consider biological teleology to be introduced by natural selection. We want to argue, however, that natural selection is not the only relevant selective process in biology. In particular, our proposal is that biological regulation is a form of biological selection. So, those who accept selected-effects theories should recognize (...)
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  9.  35
    Affordances and organizational functions.Manuel Heras-Escribano & Cristian Saborido - 2023 - Biology and Philosophy 38 (1):1-16.
    In this paper, we bring together the concepts of affordance from ecological psychology and function from the organizational approach to philosophy of biology into a single integrative framework. This integration allows us to account for the biological basis of the notion of affordance, offering theoretical tools to address the normative interrelations between organisms and their environments.
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  10.  26
    Intervalos de cuasi-descomponibilidad y propiedades emergentes.Emilio Cáceres Vázquez & Cristian Saborido - 2017 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 32 (1):89-108.
    La noción de emergencia acompaña a la Filosofía de la Biología desde finales del siglo XIX, afirmando que las propiedades de los sistemas biológicos no pueden deducirse de las de sus componentes. A lo largo del siglo XX las caracterizaciones de este concepto se han apoyado en cuatro pilares, impredecibilidad, novedad, restricción y causación descendente, pilares ligados a la asunción de una jerarquización de la realidad en niveles de organización. En este trabajo intento demostrar que puede explicarse la naturaleza de (...)
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  11. Forma, función y arquitectura biológica.Giorgio Airoldi & Cristian Saborido - 2022 - Cuadernos Filosóficos / Segunda Época 19.
    Los conceptos de evolución y cambio evolutivo son a la vez laxos y polisémicos: se aplican a fenómenos muy diferentes y no siempre se definen con precisión. La aplicación extendida del paradigma neo-darwinista clásico, además, suele imponer un esquema adaptacionista al análisis de los hechos evolutivos, en el cual las funciones juegan un papel lógicamente anterior a los rasgos y sus formas. En este artículo proponemos, como etapa previa a la formulación de hipótesis sobre las causas del cambio, un modelo (...)
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  12.  24
    ¿Realmente mató la bacteria al coronel?Emilio Cáceres Vázquez & Cristian Saborido - 2018 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 33 (1):129-148.
    En este trabajo analizamos críticamente el enfoque mecanicista de explicación científica centrándonos principalmente en la forma en la que este da cuenta de los fenómenos biológicos. Nos proponemos complementar esta perspectiva con una concepción de nivel como intervalo de cuasi-descomponibilidad que nos permite fundamentar metafísicamente las propuestas mecanicistas clásicas en las propiedades sistémicas características de las entidades biológicas. A través del análisis de ejemplos concretos, demostraremos cómo nuestra propuesta permite superar algunas de las limitaciones de los enfoques predominantes de explicación (...)
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  13.  11
    Diseases as social problems.Jesús Zamora-Bonilla & Cristian Saborido - 2024 - Synthese 203 (2):1-16.
    In this paper we articulate a characterization of the concept of disease as a social problem. We argue that, from a social ontology point of view, diseases are problems that are identified and addressed within the framework of concrete social institutions and practices (those that shape medicine). This approach allows us to overcome the classical distinction between naturalist and normativist approaches in the philosophy of medicine, taking into account both the material and the symbolic factors that shape the categories and (...)
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  14. De la selección natural al diseño: una propuesta de extensión del darwinismo formal.Giorgio Airoldi & Cristian Saborido - 2017 - Metatheoria – Revista de Filosofía E Historia de la Ciencia 8 (1):71--80.
    Darwin’s claim that Natural Selection, through optimization of fitness, explains complex biological design has not yet been properly formalized. Alan Grafen’s Formal Darwinism Project aims at providing such a formalization and at demonstrating that fitness maximization is coherent with results from Population Genetics, usually interpreted as denying it. We suggest that Grafen’s proposal suffers from some limitations linked to its concept of design as optimized fitness. In order to overcome these limitations, we propose a classification of evolutionary facts based on (...)
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  15.  57
    Incommensurability and the Extended Evolutionary Synthesis: taking Kuhn seriously.Juan Gefaell & Cristian Saborido - 2022 - European Journal for Philosophy of Science 12 (2):1-25.
    In this paper, we analyze the debate between the Modern Synthesis and the Extended Evolutionary Synthesis in light of the concept of incommensurability developed by Thomas Kuhn. In order to do so, first we briefly present both the Modern Synthesis and the Extended Evolutionary Synthesis. Then, we clarify the meaning and interpretations of incommensurability throughout Kuhn’s works, concluding that the version of this concept deployed in The Structure of Scientific Revolutions is the best suited to the analysis of scientific disputes. (...)
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  16.  25
    La guerra de la Naturaleza, la carestía y la muerte como fuente del diseño de los seres vivos.Giorgio Airoldi & Cristian Saborido - 2020 - Endoxa 46:123.
    El proyecto del ‘Darwinismo Formal’ de Alan Grafen propone una formulación matemática de la teoría de Darwin que pretende demostrar que la selección natural moldea los rasgos fenotípicos a través de la maximización de la eficacia. El proyecto de Grafen reposa sobre tres premisas: la selección natural es la única fuerza que moldea los fenotipos; la eficacia es la única medida de le evolución; y el diseño biológico surge como resultado de un proceso de optimización selectiva. En este trabajo argumentamos (...)
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  17.  15
    Morir para vivir. La muerte celular como proceso regulador.María Belén Campero, Cristián Favre & Cristian Saborido - forthcoming - Theoria. An International Journal for Theory, History and Foundations of Science.
    Usually, the organization of living systems is explained by appealing to an intrinsic purpose that is based on the biological survival. However, paradigmatically, it is inevitable to observe that the final destiny of all living organisms is death. In this work, we defend that, from an organizational approach, there is a form of death—Regulatory Cell Death—that, far from being a mere "absence of life", is a process of biological regulation and a feature of self-maintenance in multicellular organisms.
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  18.  5
    Morir para vivir. La muerte celular como proceso regulador.María Belén Campero, Cristián Favre & Cristian Saborido - 2020 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 35 (2):197-215.
    Usually, the organization of living systems is explained by appealing to an intrinsic purpose that is based on the biological survival. However, paradigmatically, it is inevitable to observe that the final destiny of all living organisms is death. In this work, we defend that, from an organizational approach, there is a form of death—Regulated Cell Death—that, far from being a mere «absence of life», is a process of biological regulation and a feature of self-maintenance in multicellular organisms.
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  19.  23
    Cultura bioética y conceptos de enfermedad: el caso House.Antonio Casado da Rocha & Cristian Saborido - 2010 - Isegoría 42:279-295.
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  20.  21
    Did the bacterium really kill the colonel? Systemic view, inter-level causation, and levels of quasi-decompositionality in mechanistic explanations.Emilio Cáceres Vázquez & Cristian Saborido - 2018 - Theoria : An International Journal for Theory, History and Fundations of Science 33 (1):129-148.
    In this paper, we critically analyze the mechanicist approach to scientific explanation and propose to complement this view with a conception of level as interval of quasi-decompositionality. This conception allows us to metaphysically base the mechanicist proposals on characteristic systemic features. By means of concrete examples, we claim that this proposal is able to overcome some of the alleged limitations of predominant models of mechanistic explanation.
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  21.  18
    Intervals of Quasi-Decompositionality and Emergent Properties.Emilio Cáceres Vázquez & Cristian Saborido - 2017 - Theoria : An International Journal for Theory, History and Fundations of Science 32 (1):89-108.
    The notion of emergence has accompanied philosophy of science since the late XIX century, claiming that in some systems there are properties in certain levels that cannot be deduced from properties of their components as seen in more fundamental levels. Throughout the XX century, emergence has been characterized by four pillars: unpredictability, novelty, restriction and downward causation. These four pillars have been related to the assumption of a hierarchical order of reality in different levels of organization. In this paper, we (...)
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  22. Cultura bioética y conceptos de enfermedad: el caso House.Antonio da Rocha & Cristian Saborido - 2010 - Isegoría 42:279-295.
    En la intersección entre la ética aplicada y los estudios sobre divulgación científica en los medios, este trabajo propone un concepto de «cultura bioética» y lo aplica a la exitosa serie de televisión House. Nuestro análisis de la serie muestra la relación existente entre la tensión entre autonomía del paciente y paternalismo médico presente en la teoría bioética y la práctica asistencial, por un lado, con el debate abierto en filosofía de la medicina entre posiciones naturalistas y normativistas sobre los (...)
     
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  23. A vueltas con la teleología en ciencias sociales.Cristian Saborido & José Francisco Alvarez - 2012 - Diálogo Filosófico 83 (83):53-72.
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  24. In search of conceptual bridges: a review of Krohs, U. & Kroes, P. "Functions in Biological and Artificial Worlds".Cristian Saborido, Matteo Mossio & Kepa Ruiz-Mirazo - 2010 - Artificial Life 16 (4):337-340.
     
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  25. La dimensión teleologica del concepto de función biológica.Cristian Saborido, Matteo Mossio & Alvaro Moreno - 2010 - Teorema: International Journal of Philosophy 29 (3):31-56.
    Most of current theoretical analyses on biological functions can be classified as etiological or dispositional, depending on how they deal with the teleological dimension. In this paper, we propose a critical survey of these two perspectives, and we argue that some recent studies have set the basis of a new approach which grounds the teleological dimension of functional attributions in the organizational properties of living systems. We outline a new proposal within this new approach, based on an interpretation of living (...)
     
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  26. Proceedings of the IX Conference of the Spanish Society of Lógic, Methodology and Philosophy of Science.Cristian Saborido, Sergi Oms & Javier González de Prado (eds.) - 2018
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  27.  15
    Justin Garson, What Biological Functions Are and Why They Matter, Cambridge: Cambridge University Press, 2019. [REVIEW]Cristian Saborido - 2021 - History and Philosophy of the Life Sciences 43 (1):1-3.
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