This study examined psychopathological correlates of implicit and explicit shame and guilt in 30 clinical and 129 non-clinical youths aged 8–17 years. Shame and guilt were measured explicitly via two self-reports and a parent report, and implicitly by means of an Implicit Association Test (IAT), while a wide range of psychopathological symptoms were assessed with questionnaires completed by children, parents, and teachers. The results showed no differences of implicit and explicit shame and guilt between the clinical and non-clinical group, implying (...) that dysregulation of these self-conscious emotions is not per definition associated with psychopathology. Correlational analyses indicated that self-reported explicit shame was positively associated with a broad range of internalizing psychopathology, while self-reported explicit guilt was associated with higher levels of anxiety and to some extent lower levels of externalizing psychopathology. Correlations with parent-rated shame and guilt revealed the same pattern of results but were in general weaker. Furthermore, implicit shame and guilt did not show significant correlations with the various measures of psychopathology. It can be concluded that the link between shame and guilt and psychopathology is complex, and partly dependent on the disorder under study and context-related factors defining the maladaptive nature of these self-conscious emotions. (shrink)

Grandiose narcissistic traits refer to exploitative and arrogant attitudes, while vulnerable narcissistic traits entail hypersensitivity to judgment and low self-esteem. Little is known about how individuals with narcissistic traits can improve their attitudes toward themselves and others. The current research puts self- and other compassion forward as possible targets to alleviate some of destructive patterns of narcissism. Generally, self-compassion has previously been associated with beneficial effects on psychological wellbeing, while other compassion is advantageous for interpersonal relationships. This study explored the (...) relationship between narcissistic traits and the efficacy of experimental compassion inductions. Student and community participants completed grandiose and vulnerable narcissistic trait, SC and OC state questionnaires, and either an SC or OC induction. It was expected that individuals with higher narcissistic traits would benefit from the inductions and show higher SC after but would have greater difficulty showing meaningful increases in OC. The results indicated that individual differences in grandiose and vulnerable narcissistic traits are related to the magnitude of improvements following the inductions: the theorized lack of SC in individuals with vulnerable oversensitivity to judgment traits seems possible to be counteracted through different types of compassion exercises. Moreover, higher grandiose exploitativeness–entitlement and global vulnerable narcissistic traits related to less increases than others. However, directly inducing OC in individuals with these traits was linked to greater OC improvements than improvements after inducing SC. Overall, the present findings suggest that self-compassionate behavior can be improved in individuals with high oversensitivity and that other compassionate behavior could potentially be increased if, specifically, other compassion exercises are utilized when higher levels of certain narcissistic traits are present. (shrink)

In this article we analyze the claim that a probabilistic interpretation of the infinite epistemic regress problem leads to a unique solution, the so called “completion” of the regress. This claim is implicitly based on the assumption that the standard Kolmogorov axioms of probability theory are suitable for describing epistemic probability. This assumption, however, has been challenged in the literature, by various authors. One of the alternatives that have been suggested to replace the Kolmogorov axioms in case of an epistemic (...) interpretation of probability, are belief functions, introduced by Shafer in 1976. We show that when one uses belief functions to describe the infinite epistemic regress problem, it is no longer the case that the solution is unique. We also argue that this complies with common sense. (shrink)

This paper provides a formal description of two legal domains. In addition, we describe the generation of various artificial datasets from these domains and explain the use of these datasets in previous experiments aligning learning and reasoning. These resources are made available for the further investigation of connections between arguments, cases and rules. The datasets are publicly available at https://github.com/CorSteging/LegalResources.

Background Voluntary post-mortem donation to science (PDS) is the most appropriate source for body dissection in medical education and training, and highly useful for biomedical research. In Mexico, unclaimed bodies are no longer a legal source, but PDS is legally possible, although scarcely facilitated, and mostly ignored by the general population. Therefore, we aimed to evaluate the attitude and willingness for PDS and to identify a sociodemographic profile of people with willingness toward PDS. Methods A validated on-line survey was distributed (...) by the convenience method via the social networks of a Catholicism-inspired, private university in northern Mexico. Frequency analyses of all variables and coded free comments were complemented with association studies. Results Although the responder cohort (n = 143) was too small and biased to be representative of the university community (n = 13,500), willingness to post-mortem organ donation was 90.7% and to PDS 70.7%. In this cohort, PDS willingness had the strongest association with mature age (> 40 years old; P, 0.0008). Among young adults, willingness to PDS was the lowest among volunteers from technical and business schools and the highest among those from the social sciences (P, 0.009). Respondents from the social sciences were also the most consistent between attitude and behavior with respect to organ donation. A free comment option revealed respondents were interested in the unusual taboo topic. Conclusions A small, but sufficiently large proportion expressed willingness toward PDS. In our university cohort, which was biased in higher education and altruism, mature age and social interest were associated with PDS willingness. (shrink)

"The only way not to to make mistakes is to wait until history has passed you by," states Bernard-Henri Lévy. But he doesn't like to wait. And that's why 'BHL', armed with a cell phone and raybans, takes off for political hot spots.""Je t'embrasse." The philosopher ends the phone call and places the tiny Ericsson cell phone on the table next to his Ray Bans. He turns to his interviewers: "Where were we?"For a moment they are lost, distracted by the (...) question of who BHL may have been 'embracing'. His wife? His mistress? Perhaps a student of French picked up casually during his lightning visit to The Netherlands? (shrink)

Name der Zeitschrift: Byzantinische Zeitschrift Jahrgang: 109 Heft: 2 Seiten: 837-860.

William Dembski (No free lunch: why specified complexity cannot be purchased without intelligence, 2002) claimed that the NFL theorems from optimization theory render darwinian biological evolution impossible. Häggström (Biology and Philosophy 22:217–230, 2007) argued that the NFL theorems are not relevant for biological evolution at all, since the assumptions of the NFL theorems are not met. Although I agree with Häggström (Biology and Philosophy 22:217–230, 2007), in this article I argue that the NFL theorems should be interpreted as dealing with (...) an extreme case within a much broader context. This broader context is in fact relevant for scientific research of certain evolutionary processes; not in the sense that the theorems can be used to draw conclusions about any intelligent design inference, but in the sense that it helps us to interpret computer simulations of evolutionary processes. As a result of this discussion, I will argue that from simulations, we do not learn much about how complexity arises in the universe. This position is in contrast with certain claims in the literature that I will discuss. (shrink)

We comment on the contributions of Dahlman and of Fenton et al., who both suggested a Bayesian approach to analyze the Simonshaven case. We argue that analyzing a full case with a Bayesian approach is not feasible, and that there are serious problems with assigning actual numbers to probabilities and priors. We also discuss the nature of Bayesian thinking in court, and the nature and interpretation of the likelihood ratio. In particular, we discuss what it could mean that a likelihood (...) ratio is in some sense uncertain. (shrink)

Teksten van 12 moderne filosofen over de mens.

As a highly technological innovation, cultured meat is the subject of techno-optimistic as well as techno-sceptical evaluations. The chapter discusses this opposition and connects it with arguments about seeing the world in the right way. Both sides not only call upon us to see the world in a very particular light, but also point to mechanisms of selective attention in order to explain how others can be so biased. I will argue that attention mechanisms are indeed relevant for dealing with (...) the Anthropocene, but that dualism has paralysing effects. In a dualistic framework, cultured meat is associated with ecomodernist optimism, bold technological control over nature and alienation from animals. But interested citizens and farmers in focus groups rather envisioned the future of cultured meat through small scale production on farms combined with intensive relations with animals. Such scenarios, involving elements from both sides of the dualistic gap, depend on constructive ways of dealing with dualisms and ambivalence. (shrink)

This article seeks to state, first, what traditionally has been assumed must be the case in order for an infinite epistemic regress to arise. It identifies three assumptions. Next it discusses Jeanne Peijnenburg's and David Atkinson's setting up of their argument for the claim that some infinite epistemic regresses can actually be completed and hence that, in addition to foundationalism, coherentism, and infinitism, there is yet another solution (if only a partial one) to the traditional epistemic regress problem. The article (...) argues that Peijnenburg and Atkinson fail to address the traditional regress problem, as they don't adopt all of the three assumptions that underlie the traditional regress problem. It also points to a problem in the notion of making probable that Peijnenburg and Atkinson use in their account of justification. (shrink)

On 10 July 1973, Laurens, our second son, was born in the same Dutch hospital where I worked as an intensive care physician. Two weeks after we brought him. home from the hospital, my wife heard him crying at about 5:45 A.M. Rather than going to him, she decided to wait until his scheduled feeding time. At about 6:10 when she went to Laurens's room to feed him, she saw him. face down in the corner of his crib. He appeared (...) dead. She screamed for me. I ran from upstairs to Laurens's room on the ground floor. I initiated cardio-pulmonary resuscitation and continued the CPR while my wife called our general practitioner. He arrived in about 10 minutes and the ambulance arrived a minute later. (shrink)

Although most people still behave like happy meat eaters, there are good reasons to think that many are in fact ambivalent about meat. Following up on earlier findings, in this paper we describe how, in focus groups, cultured meat triggered much discussion about meat, especially among older people. While young people wondered whether they would eat cultured meat products, older people thought about diet changes in a historical perspective and wondered if and how cultured meat might become a societal success. (...) Beneath the surface of everyday behavior, in which they followed mainstream norms, many of our research participants harbored moral concerns and in various ways expressed an interest in collective change. Reflecting on the focus group discussions, we suggest, first, that appreciating the important role of ambivalence in processes of moral change requires rethinking relations between ambivalence and morality. Second, the entanglement of ambivalence with ambiguity increases the “fluidity” of such processes of change: when it is no longer clear what exactly meat is, the meanings and experiences of eating it also become unsettled. This has implications for thinking about morality in times of change. Studying consumer choices cannot do justice to processes of ambivalence and ambiguity below the surface of behavior. More generally, the idea that morality resides in making up our minds about clear moral choices gives way to the need to become skilled, collectively as well as individually, in dealing imaginatively with ambivalence and ambiguity. (shrink)

Official Dutch food information apparently tries to avoid images but is implicitly shaped by the metaphor that food is fuel. The image of food as fuel and its accompanying view of the body as a machine are not maximally helpful for integrating two important human desires: health and pleasure. At the basis of the split between health and pleasure is the traditional mind–body dichotomy, in which the body is an important source of evil and bodily pleasure is sinful and dangerous. (...) In the search for alternatives, new metaphors are proposed that integrate mind and body as well as pleasure and health. The relevance of metaphors for ethics is at least twofold. (1) Moral thought and theory are at least partly shaped by metaphors. In the light of this growing recognition, the analysis of morality needs innovation. (2) With regard to food, new metaphors, such as slow food, or the image of enjoyment as an art, enable a new search for morally responsible forms of hedonism, based on more love and respect for human as well as animal bodies. But new metaphors are specific and selective, just like old ones. I argue that a search for the best overall metaphor would be misguided, but that more diverse forms of attention to bodily aspects of life, including experiences related to food, will result in richer vocabularies of the body, the mind, and body–mind relations. This holds a promise of moral progress. (shrink)

Should we put our agricultural hopes in new technologies or in regenerative approaches? Dualisms, and their suggestion that we must choose, frame many debates. By offering just two options, they tend to discourage more wideranging and creative searches. Yet dualism can also be helpful, for example in the form of critical discussion, an antidote against confirmation bias and wishful thinking. But then again, critical dialogue is not necessarily connected with the dualism of winning or losing. Why choose, if we are (...) actually ambivalent? This lecture looks for pragmatic ways of dealing with dualisms. It proposes pilot farms as places, and as metaphors, for finding new directions on the basis of tensions, through back and forth thinking between tradition and innovation. (shrink)

With regard to the theoretical place of environmental factors in development, three approaches to evolution and development can be distinguished. One is the neo-Darwinist approach in which genetic programs are central. The other two present themselves as alternatives to the gene-centrism in present-day biology. I discuss pairwise similarities and differences between the three approaches. Goodwin's approach differs from neo-Darwinism in its favoured types of causes, but shares the internalist perspective on embryological development. The constructionist alternative proposes to enlarge the developmental (...) system to include external factors, and shares with neo-Darwinism the emphasis on contingent causes. Thus there is neither a grand dichotomy in biology, between neo-Darwinism and its alternative, nor a grand trichotomy. Different purposes make different approaches useful. I conclude by arguing that environmental influences should have a more prominent place in developmental biology. (shrink)

Ectopeptidases are transmembrane proteins present in a wide variety of tissues and cell types. Dysregulated expression of certain ectopeptidases in human malignancies suggests their value as clinical markers. Ectopeptidase interaction with agonistic antibodies or their inhibitors has revealed that these ectoenzymes are able to modulate bioactive peptide responses and to influence growth, apoptosis and differentiation, as well as adhesion and motility, all functions involved in normal and tumoral processes. There is evidence that ectopeptidase-mediated signal transduction frequently involves tyrosine phosphorylation. Combined (...) analyses of gene organization and regulation of ectopeptidases by various physiological factors have provided insights into their structure–function relationships. Understanding the roles of ectopeptidases in pathophysiology may have implications in considering them as therapeutic targets. BioEssays 23:251–260, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

This article seeks to state, first, what traditionally has been assumed must be the case in order for an infinite epistemic regress to arise. It identifies three assumptions. Next it discusses Jeanne Peijnenburg's and David Atkinson's setting up of their argument for the claim that some infinite epistemic regresses can actually be completed and hence that, in addition to foundationalism, coherentism, and infinitism, there is yet another solution (if only a partial one) to the traditional epistemic regress problem. The article (...) argues that Peijnenburg and Atkinson fail to address the traditional regress problem, as they don't adopt all of the three assumptions that underlie the traditional regress problem. It also points to a problem in the notion of making probable that Peijnenburg and Atkinson use in their account of justification. (shrink)

The technology required for tissue-engineering food is the same as for medical applications, and in fact is derived from it. There are major differences in the implementation of those technologies, primarily related to the enormous scale required for food production and the different economical framework. In addition, the emotional context of food tissue engineering is also more complex than for medical applications. On the other hand, the tissues that are generated do not need to integrate in the body, with less (...) risk of adverse effects in the event of incomplete functional, neuronal or humoral adaptation. The implementation of tissue engineering for food is still in its infancy. No products exist yet. It will be extremely challenging to make these products a reality for the consumer, but the reward and return in terms of value for our society will be tremendous. (shrink)

Questions the dominant biological approach of explaining animal development as entirely genetic by exploring the explanatory value of investigating environmental influences.

This paper explores the ambiguous notion of bodily integrity, focusing on male and female circumcision. In the empirical part of the study we describe and analyse the various meanings that are given to the notion of bodily integrity by people in their daily lives. In the philosophical part we distinguish (1) between a person-oriented and a body-oriented approach and (2) between four levels of interpretation, i.e. bodily integrity conceived of as a biological wholeness, an experiential wholeness, an intact wholeness, and (...) as an inviolable wholeness. We argue that bodily integrity is a prima facie principle in its own right, closely connected with, but still fundamentally different from, the principle of personal autonomy, that is, autonomy over the body. (shrink)

Two approaches to an integration of evolution and development are often distinguished, one neo-Darwinian and the other structuralist. Should these approaches in turn be integrated? Kelly Smith recently stated that we need a more complete theory of biological order, suggesting integration as the ideal. In response to him, I argue that a recognition of different types of scientific questions and causal explanation is more urgent. Do we understand development when we know the crucial factors in the process of differentiation, or (...) rather when we know the laws that govern the transformations of fields? Without a recognition of these different explanatory ideals, integration is likely to have the character of annexation. (shrink)

To deal with the upcoming challenges and complexity of the nursing profession, it is deemed important to reflect on our current organization of care. However, before starting to rethink the organization of nursing care, an overview of important elements concerning nursing care organization, more specifically nursing models, is necessary. The aim of this study was to conduct a mapping review, accompanied by an evidence map to map the existing literature, to map the field of knowledge on a meta‐level and to (...) identify current research gaps concerning nursing models in a hospital setting. Next to nursing models, two other organizational correlates seem to be of importance when looking at the organization of nursing care: nurse staffing and skill mix. Although it seems that in recent research, the theoretical focus on the organization of nursing care has been left behind, the increasingly complex healthcare environment might gain from the use of nursing theory, or in this case, care delivery models. As almost no fundamental studies have been done toward the combination of care delivery models, nurse staffing, and skill mix, those elements should be taken into account to fully capture the organization of nursing care in future research. (shrink)

Frans de Waal’s view that empathy is at the basis of morality directly seems to build on Darwin, who considered sympathy as the crucial instinct. Yet when we look closer, their understanding of the central social instinct differs considerably. De Waal sees our deeply ingrained tendency to sympathize (or rather: empathize) with others as the good side of our morally dualistic nature. For Darwin, sympathizing was not the whole story of the workings of sympathy ; the (selfish) need to receive (...) sympathy played just as central a role in the complex roads from sympathy to morality. Darwin’s understanding of sympathy stems from Adam Smith, who argued that the presence of morally impure motives should not be a reason for cynicism about morality. I suggest that De Waal’s approach could benefit from a more thorough alignment with the analysis of the workings of sympathy in the work of Darwin and Adam Smith. (shrink)

With regard to the theoretical place of environmental factors in development, three approaches to evolution and development can be distinguished. One is the neo-Darwinist approach in which ‘genetic programs’ are central. The other two present themselves as alternatives to the gene-centrism in present-day biology. I discuss pairwise similarities and differences between the three approaches. Goodwin's approach differs from neo-Darwinism in its favoured types of causes, but shares the internalist perspective on embryological development. The ‘constructionist’ alternative proposes to enlarge the developmental (...) system to include external factors, and shares with neo-Darwinism the emphasis on contingent causes. Thus there is neither a grand dichotomy in biology, between neo-Darwinism and its alternative, nor a grand trichotomy. Different purposes make different approaches useful. I conclude by arguing that environmental influences should have a more prominent place in developmental biology. (shrink)

New technology has a prominent place in the theory and practice of innovation, but the association between high tech and innovation is not inevitable. In this paper, we discuss six metaphorical heroes of agricultural innovation, starting with the dominant hero of frontier science and technology. At first sight, our six heroes can be divided in those who are pro- and those who are anti-technology. Yet in the end technology, and more specifically GM technology, does not emerge as the main issue. (...) Empowering the poor, finding solutions for urgent climate problems, and enhancing the quality of our daily relations to food and the environment – these are the issues the heroes are fighting for. Relations between innovation and technology are better seen as a matter of pragmatic consideration, we will argue. (shrink)