pte. 1. Teoria generale dello stato moderno.

Research integrity (RI) is defined as adherence to ethical principles, deontological duties, and professional standards necessary for responsible conduct of scientific research. Early training on RI, especially for early-career researchers, could be useful to help develop good standards of conduct and prevent research misconduct (RM).The aim of this study is to assess the effectiveness of a training course on RI, by mapping the attitudes of early-career researchers on this topic through a questionnaire built upon the revised version of the Scientific (...) Misconduct Questionnaire and administered to all participants at the beginning and at the end of the course.Results show that after the course, participants reporting a high understanding of the rules and procedures related to RM significantly increased (pre-course: 38.5%, post-course: 61.5%), together with the percentage of those reporting a lack of awareness on the extent of misconduct (pre-course: 46.2%, post-course: 69.2%), and of those who believe that the lack of research ethics consultation services strongly affects RM (pre-course: 15.4%, post-course: 61.5%). Early-career researchers agree on the importance to share with peers and superiors any ethical concern that may arise in research, and to create a work environment that fosters RI awareness.As a whole, results suggest the effectiveness of the course. Institutions should introduce RI training for early-career researchers, together with research methodology, integrity and ethics consultation services to support them. Senior scientists should promote RI into their research practices, and should stimulate engagement in peer-to-peer dialogue to develop good practices based on RI principles. (shrink)

La ley jurídica preserva sorprendentemente un contenido de ínsita verdad y solidez, caracteres de los que aún la ley científica, siempre hipotética y provisoria, ya no presume. En el presente artículo se pretende esbozar un camino hacia la explicación de este anacronismo, a través de las modalidades asumidas por la ley para hacer regir las regularidades del mundo. La ley es una estrategia para controlar el espacio y eludir el tiempo. Cada época ha tenido sus formas de llevar a cabo (...) ese control / elusión, desde una certeza original que le sirva de ubicación y referencia. Los valores de la ley están relacionados con el residuo de cada una de las certezas originales sobre las que se instauró históricamente. A fin de obtener dichos fines, necesita tanto de la sedimentación de las sucesivas capas de venerabilidad, como del ahogo de la memoria y del tiempo y de la historia que las han concebido y desarrollado. (shrink)

Tra le avventure del pensiero che la nostra epoca può consegnare con orgoglio alla storia della scienza, una delle più intense e affascinanti è senz’altro l’evento della genesi e dello sviluppo dell’approccio scientifico ai tradizionali problemi della conoscenza. Si è trattato innanzitutto del difficile superamento di un confine disciplinare antico, quel limite che Descartes ha tracciato agli albori della tradizione scientifica moderna e che nel tempo si è trasformato in un vuoto concettuale...

Between December 2020 and March 2021, the US Food and Drug Administration and the European Medicines Agency issued Emergency Use Authorizations and Conditional Marketing Authorizations for the distribution of the first COVID-19 vaccines. Although these vaccines were thoroughly assessed before their approval, regulators required companies to continue ongoing placebo-controlled clinical trials in order to gather further reliable scientific information on their safety and efficacy, as well as to start new studies to evaluate additional candidates. The aim of this paper is (...) to present and discuss the ethical issues raised by the tension between the need to continue these types of clinical trials and the obligations related to the protection of the rights and well-being of research participants. Specifically, we question whether—how, and to what extent—fundamental principles governing research involving human beings can be applied to the current pandemic situation. We argue that continuing ongoing placebo-controlled clinical trials can be considered ethically justifiable only if all participants are adequately informed of any developments that may affect their willingness to remain enrolled, including the current situation of resource scarcity and the prioritization criteria established for vaccination. However, we also argue that currently approved vaccines, which are considered safe and effective enough to be administered to millions of people as part of the vaccination campaign, necessarily represent the “best proven intervention” currently available and, therefore, should be used as comparators in future studies instead of placebo. (shrink)

This article addresses the power of human technologies to wreak destruction on a planetary scale, such as genetic manipulation and weapons of mass destruction. It proposes the need for a new ethic that would be planetary in scale. Its central aim would be to include the great historical and contemporary diversity of human cognitive and epistemological experience. An "ethic of complexity" can weave together the threads of our common heritage. Although humanity's evolutionary past has been shown to be quite diverse, (...) recent genetic and anthropological research has shown it also to be surprisingly unified. New images and metaphors are providing humanity with a vision that transcends familiar ethnic hatreds and so-called clashes of civilizations. The new planetary culture can be a shining example of unity-in-diversity, or unitas multiplex. It will be robustly diverse, intermixed to the core, and filled with awe at the rich lineages of our common past. (shrink)

This article looks at the prevalent view of time in the history of Western philosophy and science and then contrasts it with the emerging new vision of time as ontologically constructive. Throughout Western history, philosophers and scientists attempted to marginalize and anesthetize the role of time by prioritizing being over becoming. But beginning with the Darwinian revolution in biology, the West could no longer deny the constructive role of time in bringing forth new ontological orders. While the 20th century witnessed (...) the split between the reversible time of physics and the developmental time of biology, the time has now come for this divide to be reconciled. Twenty-first century science is already revealing the constructive role of time in cosmology with the likelihood of multiple universes. In conclusion, the authors speculate that our moment in human cultural development is ripe for a complex, multidimensional, and transdisciplinary understanding of time. (shrink)

Après des siècles de développement parallèle, l’histoire des communautés humaines a connu un tournant majeur en 1492, l’expansion vers d’autres continents rendant les sociétés de plus en plus interdépendantes. Parvenue à l’ère planétaire, l’humanité mondialisée doit opérer une nouvelle évolution en instaurant une relation non destructrice avec la nature, afin de garantir sa propre survie.After centuries of parallel development, the history of human communities was a major turning point in 1492, expanding to other continents making companies increasingly interdependent. Reached in (...) the global era, humanity must make a global change by introducing a new non-destructive relationship with nature to ensure its own survival. (shrink)

ResumenEste artículo propone una idea de intervención e institución que se entrelace en lo social a través del concepto de contagio como elemento filosófico articulador. En primer lugar, se establece un marco teórico-filosófico para pensar la vida como una ontología social del contagio, que permita habitar un pensar relacional etológico que se abra a otros modos de existencia. Desde este marco, los hallazgos perfilan la relación intervención-institución desde la sensibilidad que evoca esta forma distinta de intervención en lo social, disponiendo (...) de otros modos las variaciones de la institución y sus procesos de instituir el campo social. Se concluye discutiendo la relación entre intervención y sus capacidades transformativas como componente metódico y epistemológico distinto que trae consigo un fuerte potencial político y ético. Al multiplicar los modos de ser y los procesos de subjetivación se abren prácticas humanas y más-que-humanas, instituyendo otros modos de hacer-y-pensar toda intervención del presente.Palabras clave: institución; intervención; contagio; formas de vida; cartografías. (shrink)