The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

There are growing concerns that increased screen device usage may have a detrimental impact on classroom behaviour and attentional focus. The consequences of screen use on child cognitive functioning have been relatively under-studied, and results remain largely inconsistent. Screen usage may displace the time usually spent asleep. The aim of this study was to examine associations between screen use, behavioural inattention and sustained attention control, and the potential modifying role of sleep. The relations between screen use, behavioural inattention, sustained attention (...) and sleep were investigated in 162 6- to 8-year-old children, using parent-reported daily screen use, the SWAN ADHD behaviour rating scale, The sustained attention to response task and the children’s sleep habits questionnaire. Tablet use was associated with better sustained attention performance but was not associated with classroom behavioural inattention. Shorter sleep duration was associated with poorer behavioural inattention and sustained attention. Sleep quality and duration did not act as mediators between screen usage and behavioural inattention nor sustained attention control. These findings suggest that careful management of the amount of time spent on electronic screen devices could have a beneficial cognitive impact on young children. The results also highlight the critical role of sleep in enhancing both behavioural attention and sustained attention, which are essential for supporting cognitive development and learning. (shrink)

Three experiments examined repetition priming for meaningful environmental sounds in a sound stem identification paradigm using brief sound cues. Prior encoding of target sounds together with their associated names facilitated subsequent identification of sound stems relative to nonstudied controls. In contrast, prior exposure to names alone in the absence of the environmental sounds did not prime subsequent sound stem identification performance at all . Explicit and implicit memory were dissociated such that sound stem cued recall was higher following semantic than (...) nonsemantic encoding, whereas sound priming was insensitive to manipulations of depth encoding . These results extend the findings of long-term repetition priming into the auditory nonverbal domain and suggest that priming for environmental sounds is mediated primarily by perceptual processes. (shrink)

Creativity and morality are key attributes that stakeholders demand of organizations. Accordingly, higher education institutions and professional training programs also seek to cultivate these attributes in future leaders. However, research has hitherto shown that, under certain conditions, creativity may conflict with morality. This complicates the development of creative individuals who are also moral. We examined the complex relationship between creativity and moral reasoning with data collected from a group of undergraduate students. By considering the cognitive processes behind creativity and moral (...) reasoning, we propose perspective taking as a moderating factor. Specifically, we found that while creative individuals might not necessarily adopt a lower level of moral reasoning, there was a more nuanced moderating relationship among creativity, perspective taking, and moral reasoning. That is, individuals who were weak in perspective taking tended to adopt a lower level of moral reasoning if they were also creative. Perspective taking was also directly and positively associated with moral reasoning. We explore the implications of our findings for future research and curriculum/program design. (shrink)

*North American Society for Social Philosophy (NASSP) Book Award 2019.* -/- *International Studies Association (ISA) - International Ethics Section Book Award 2021.* -/- Although military mores have relied primarily on just war theory, the ethic of cooperation in warfare (ECW)—between enemies even as they are trying to kill each other—is as central to the practice of warfare and to conceptualization of its morality. Neither game theory nor unilateral moral duties (God-given or otherwise) can explain the explicit language of cooperation in (...) developing and enforcing principles of military ethics and the law of armed conflict. -/- The ethic of cooperation is borne of various motivations: reciprocity, self-preservation, and efficiency, to be sure, but also a sense of warrior honor and concern with human rights. This shared morality can persist despite making it more difficult for one side or the other to win and, unfortunately, its well-meaning motivations often lead to unintended tragic consequences. -/- This book explores three manifestations of this significant yet overlooked ethic of cooperation in warfare: (1) for a “fair fight,” (2) to protect classes of individuals (e.g., non-combatants or prisoners of war), and (3) to end the war quickly. Such cooperation can take unexpected forms, from ad hoc decisions on the battlefield to institutionalization in international law, and is the source of some critical tensions in one of the most significant developments in warfare in recent years: namely, how to handle terrorism or other forms of warfare that lie outside the purview of international law. -/- Each type of ECW raises questions internal to that ethic, such as inconsistencies in the concept of “parity” across different weapons bans, contradictions within the warrior ethic that heavily influence—and therefore confuse—notions of the “fair fight,” the disconnect between what protections a person receives and his responsibility for the war (e.g., political leaders), or the limited decisiveness of outcomes generated by very short wars. -/- Their simultaneous application also generates significant tensions and raises questions about the proper relationship of ECW to the immediate goal of war itself, which is to win, and thus yield either a political settlement or a justicial decision. For example, the ECWs for a “fair fight” and to protect classes of individuals can make it harder to win the war, but even more concerning is that they can also kill more people, which in the latter case contravenes its very purpose. -/- Human history is in some ways the story of trying to concurrently wage and tame war, and the architecture of warfare itself is informed by the ECW, in particular: (a) the political nature of war, (b) the abdication from jus ad bellum judgments in order to concentrate on justice within war (jus in bello), and (c) the ways in which modern nation-states collude to define “legitimacy” in war. -/- The combination of these three features leave questions of justicial right and responsibility for war disturbingly unresolved, it also generates new challenges in a geopolitical context in which cooperative and non-cooperative (e.g. contemporary terrorism) forms of warfare clash. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Prospects for a Mahāyāna Theology of EmptinessA Continuing DebateJohn P. KeenanTwo articles in recent issues of Buddhist-Christian Studies—Lai Pan-chiu’s “A Mahāyāna Reading of Chalcedon Christology: A Chinese Response to John Keenan” 1 (2004) and Thomas Cattoi’s “What Has Chalcedon to Do with Lhasa? John Keenan’s and Lai Pan-chiu’s Reflections on Classical Christology and the Possible Shape of a Tibetan Theology of Incarnation” 2 (2008)—discuss my book (...) The Meaning of Christ: A Mahāyāna Theology (1989),3 prompting me to add my voice to the conversation.In “A Mahāyāna Reading of Chalcedon Christology: A Chinese Response to John Keenan,” Lai Pan-chiu reads from the perspective of a Chinese Christian thinker my formulation of a Christology informed by Indian Mahāyāna philosophy. He would prefer to configure a rather different Mahāyāna theology, wherein the polarity expressed in traditional Chalcedonian theology would be reinvested in a Chinese Mahāyāna dynamic, with its ability to hold in creative tension what are often seen as exclusionary opposites. Lai proposes to take as leitmotif for this project the Chinese Mahāyāna theme of Buddha Nature (C. fóxìng ) and its Indian precursor of Tathāgatagarbha (Skt. “matrix of the Buddha”) thought. Although—for reasons I will discuss below—I would not myself choose this approach in writing Christology for a western audience, I certainly would commend Lai Pan-chiu’s effort to do so for a Chinese audience and beyond.In “What Has Chalcedon to Do with Lhasa? John Keenan’s and Lai Pan-chiu’s Reflections on Classical Christology and the Possible Shape of a Tibetan Theology of Incarnation,” Thomas Cattoi contends that Lai has not gone far enough in responding to The Meaning of Christ. Cattoi himself then proceeds with a critique of Mahāyāna theology that reveals both his own unwavering commitment to traditional ontological theology and his apparent disinterest in engaging Buddhist Mahāyāna philosophy in depth. He makes little or no reference to the Mahāyāna philosophical themes that I discuss in detail in The Meaning of Christ—themes that I then employ to enunciate a Mahāyāna Christology. Moreover, the alternative “Tibetan Christology” that Cattoi proffers in this article also appears to avoid any deep or detailed engagement [End Page 3] with Mahāyāna thought. He seems satisfied to employ Tibetan Buddhist terminology simply to reaffirm what we have long affirmed in the Greek, emphasizing the embodiment of Christ as the unicum, the one and only embodiment of God, and the transformation of the very fabric of the universe effected thereby.4 His Christology functions as a description of that transformation and, to my lights, leaves scant room for any Trinitarian theology of the Spirit. He argues against the notion that any discourse can empty the ontological claims of “the Christian position.” For him, only the ontological theology of our Greek ancestors is adequate—apparently culturally privileged because providentially inspired.I will address herein some of the many, often convoluted, issues raised, for these issues are basic to Mahāyāna theology and to critiques against its viability. I choose not to detail the many instances in which Thomas Cattoi misreads, mischaracterizes, and misrepresents my work; I must only trust that those who have read The Meaning of Christ are well aware that Cattoi’s characterizations of that book reflect neither its content nor its tone.5 I shall use this space instead to further clarify the shape of a Mahāyāna theology that employs the principal themes of Mādhyamika and Yogācāra, and will discuss in a more general way Cattoi’s fundamental inattentiveness to those themes and to the manner in which they inform Mahāyāna theology.6 I shall also discuss Lai Pan-chiu’s very interesting proposal for a Chinese Mahāyāna theology.Ontology and MahĀyĀna Realms of UnderstandingMahāyāna theology is not Cattoi’s “Mādhyamika dualism.”7 Mahāyāna theology does not represent a Buddhist “position,” but rather the emptiness of all... (shrink)

Holobionts are symbiotic assemblages composed by a macrobe host plus its symbiotic microbiota. In recent years, the ontological status of holobionts has created a great amount of controversy among philosophers and biologists: are holobionts biological individuals or are they rather ecological communities of independent individuals that interact together? Chiu and Eberl have recently developed an eco-immunity account of the holobiont wherein holobionts are neither biological individuals nor ecological communities, but hybrids between a host and its microbiota. According to their (...) account, the microbiota is not a proper part of the holobiont. Yet, it should be regarded as a set of scaffolds that support the individuality of the host. In this paper, we approach Chiu and Eberl’s account from a metaphysical perspective and argue that, contrary to what the authors claim, the eco-immunity account entails that the microorganisms that compose the host’s microbiota are proper parts of the holobiont. Second, we argue that by claiming that holobionts are hybrids, and therefore, not biological individuals, the authors seem to be assuming a controversial position about the ontology of hybrids, which are conventionally characterized as a type of biological individual. In doing so, our paper aligns with the contemporary tendency to incorporate metaphysical resources to shed light on current biological debates and builds on that to provide additional support to the consideration of holobionts as biological individuals from an eco-immunity perspective. (shrink)