Journal editorials, career features, and the popular press commonly talk of a graduate student mental health crisis. To date, studies on graduate student mental health have employed cross-sectional designs, limiting any causal conclusions regarding the relationship between entry into graduate study and mental health. Here, we draw on data from a longitudinal study of undergraduate students in Aotearoa New Zealand, allowing us to compare participants who did, and did not, transition into PhD study following the completion of their undergraduate degree. (...) Using multilevel Bayesian regression, we identified a difference in mental wellbeing between those who entered PhD study and those who did not. This difference, however, was largely due to those not entering PhD study displaying an increase in mental wellbeing. Participants that entered PhD study displayed a small decrease in mental wellbeing, with the posterior distribution of the simple effect heavily overlapping zero. This latter finding was orders of magnitude smaller than one might expect based on previous cross-sectional research and provides an important message; that a marked drop in mental health is not an inevitable consequence of entering graduate study. (shrink)

We argue that Tomasello's account overlooks important psychological distinctions between how humans judge different types of moral obligations, such as prescriptive obligations and proscriptive obligations. Specifically, evaluating these different types of obligations rests on different psychological inputs and has distinct downstream consequences for judgments of moral character.

Compassion is a prosocial motivation that is critical to the development and survival of the human species. Cultivating compassion involves developing deep wisdom, insight, and understanding into the nature and causes of human suffering; and wisdom and commitment to take positive action to alleviate suffering. This perspective piece discusses how compassion relates to the context of modern technology, which has developed at a rapid pace in recent decades. While advances in digital technology build on humankind’s vast capacity to develop practical (...) tools that promise to enrich our lives and improve our social connections, in reality the effects are often far from benign. The motives underlying the development of many contemporary digital platforms seem rooted in competitiveness and capitalism; while modern social media and online platforms are having a profound and pervasive impact on the mental health and wellbeing of humans around the globe. Nonetheless, digital technology holds considerable potential to promote compassionate insight, wisdom, and prosocial behavior. We reflect on the current state of technology within human society and examine the notion of compassionate technologies; discuss how contemporary paradigm shifts such as the inclusive design movement may be harnessed to build tools and platforms that promote collective good and increase prosocial behavior; and highlight examples of initiatives that are harnessing modern technology to advance democracy, collective knowledge, and personal freedoms and agency. (shrink)

Genomic research results and incidental findings with health implications for a research participant are of potential interest not only to the participant, but also to the participant's family. Yet investigators lack guidance on return of results to relatives, including after the participant's death. In this paper, a national working group offers consensus analysis and recommendations, including an ethical framework to guide investigators in managing this challenging issue, before and after the participant's death.

Scientists routinely solve the problem of supplementing one’s store of variables with new theoretical posits that can explain the previously inexplicable. The banality of success at this task obscures a remarkable fact. Generating hypotheses that contain novel variables and accurately project over a limited amount of additional data is so difficult—the space of possibilities so vast—that succeeding through guesswork is overwhelmingly unlikely despite a very large number of attempts. And yet scientists do generate hypotheses of this sort in very few (...) tries. I argue that this poses a dilemma: either the long history of scientific success is a miracle, or there exists at least one method or algorithm for generating novel hypotheses with at least limited projectibility on the basis of what’s available to the scientist at a time, namely a set of observations, the history of past conjectures, and some prior theoretical commitments. In other words, either ordinary scientific success is miraculous or there exists a logic of discovery at the heart of actual scientific method. (shrink)

In addition to considering sociocultural, political, economic, and ethical factors, effectively engaging socioscientific issues requires that students understand and apply scientific explanations and the nature of science. Promoting such understandings can be achieved through immersing students in authentic real-world contexts where the SSI impacts occur and teaching those students about how scientists comprehend, research, and debate those SSI. This triangulated mixed-methods investigation explored how 60 secondary students’ trophic cascade explanations changed through their experiencing place-based SSI instruction focused on the Yellowstone (...) wolf reintroduction, including scientists’ work and debates regarding that issue. Furthermore, this investigation determined the association between the students’ post place-based SSI instruction trophic cascade explanations and NOS views. Findings from this investigation demonstrate that through the place-based SSI instruction students’ trophic cascade explanations became significantly more accurate and complex and included more ecological causal mechanisms. Also, significant and moderate to moderately large correlations were found between the accuracy and contextualization of students’ post place-based SSI instruction NOS views and the complexity of their trophic cascade explanations. Empirical substantiation of the association between the complexity of students’ scientific explanations and their NOS views responds to an understudied area in the science education research. It also encourages the consideration of several implications, drawn from this investigation’s findings and others’ prior work, which include the need for NOS to be forefront alongside and in connection with science content in curricular standards and through instruction focused on relevant and authentic place-based SSI. (shrink)

The Proceedings of the National Summit on Legal Preparedness for Obesity Prevention and Control is based on a two-part conceptual framework composed of public health and legal perspectives. The public health perspective comprises the six target areas and intervention settings that are the focus of the obesity prevention and control efforts of the Centers for Disease Control and Prevention.This paper presents the legal perspective. Legal preparedness in public health is the underpinning of the framework for the four “assessment” papers and (...) the four “action” papers that are integral to the application of public health law to any particular health issue. In addition, this paper gives real-world grounding to the legal framework through examples that illustrate the four core elements of legal preparedness in public health that are at work in obesity prevention and control. (shrink)

The Proceedings of the National Summit on Legal Preparedness for Obesity Prevention and Control is based on a two-part conceptual framework composed of public health and legal perspectives. The public health perspective comprises the six target areas and intervention settings that are the focus of the obesity prevention and control efforts of the Centers for Disease Control and Prevention.This paper presents the legal perspective. Legal preparedness in public health is the underpinning of the framework for the four “assessment” papers and (...) the four “action” papers that are integral to the application of public health law to any particular health issue. In addition, this paper gives real-world grounding to the legal framework through examples that illustrate the four core elements of legal preparedness in public health that are at work in obesity prevention and control. (shrink)

Public health emergencies have occurred throughout history, encompassing such events as plagues and famines arising from natural causes, disease pandemics interrelated with wars, and industrial accidents such as the 1986 Chernobyl disaster, among others. Law and legal tools have played an important role in addressing such emergencies. Three prime U.S. examples are Congressional authorization of quarantine as early as 1796, legally mandated smallpox vaccination upheld in a landmark 1905 U.S. Supreme Court ruling, and the President's 2003 executive order adding SARS (...) to the federal government's list of “quarantinable communicable diseases.”The public health emergencies of the present — both actual and potential — pose equally serious threats but do so in the context of greatly magnified expectations that stem directly from the attacks of September 11, 2001, and the immediately following anthrax attacks. (shrink)

In a naïve realist approach to reading an ontology off the models of a physical theory, the invariance of a given theory under permutations of its property-bearing objects entails the existence of distinct possible worlds from amongst which the theory cannot choose. A brand of Ontic Structural Realism attempts to avoid this consequence by denying that objects possess primitive identity, and thus worlds with property values permuted amongst those objects are really one and the same world. Assuming that any successful (...) ontology of objects is able to describe a universe containing a determinate number of them, I argue that no version of OSR which both retains objects and understands ‘structure’ in terms of relations can be successful. This follows from the fact that no set of relational facts is sufficient to fix the cardinality of the collection of objects implied by those facts. More broadly, I offer reasons to believe that no version of OSR is compatible with the existence of objects, no matter how ontologically derivative they are taken to be. Any such account would have to attribute a definite cardinality to a collection of objects while denying that those objects are possessed of a primitive identity. With no compelling reason to abandon the classical conception of cardinality, such an attribution is incoherent. (shrink)

Public health emergencies have occurred throughout history, encompassing such events as plagues and famines arising from natural causes, disease pandemics interrelated with wars, and industrial accidents such as the 1986 Chernobyl disaster, among others. Law and legal tools have played an important role in addressing such emergencies. Three prime U.S. examples are Congressional authorization of quarantine as early as 1796, legally mandated smallpox vaccination upheld in a landmark 1905 U.S. Supreme Court ruling, and the President's 2003 executive order adding SARS (...) to the federal government's list of “quarantinable communicable diseases.”The public health emergencies of the present — both actual and potential — pose equally serious threats but do so in the context of greatly magnified expectations that stem directly from the attacks of September 11, 2001, and the immediately following anthrax attacks. (shrink)

Scientific practice involves two kinds of induction. In one, generalizations are drawn about the states of a particular system of variables. In the other, generalizations are drawn across systems in a class. We can discern two questions of correctness about both kinds of induction: what distinguishes those systems and classes of system that are ‘projectible’ in Goodman’s sense from those that are not, and what are the methods by which we are able to identify kinds that are likely to be (...) projectible? In answer to the first question, numerous theories of ‘natural kinds’ have been advanced, but none has satisfactorily addressed both questions simultaneously. I propose a shift in perspective. Both essentialist and cluster property theories have traditionally characterized kinds directly in terms of the causally salient properties their members possess. Instead, we should focus on ‘dynamical symmetries’, transformations of a system to which the causal structure of that system is indifferent. I suggest that to be a member of natural kind it is necessary and sufficient to possess a particular collection of dynamical symmetries. I show that membership in such a kind is in turn necessary and sufficient for the presence of the sort of causal structure that accounts for success in both kinds of induction, thus demonstrating that has been answered satisfactorily. More dramatically, I demonstrate that this new theory of ‘dynamical kinds’ provides an answer to with methodological implications concerning the discovery of projectible kinds. (shrink)

The active debate about the return of incidental or secondary findings in research has primarily focused on return to research participants, or in some cases, family members. Particular attention has been paid to return of genomic findings. Yet, research may generate other types of findings that warrant consideration for return, including findings related to the pathology of donated biospecimens. In the case of deceased biospecimen donors who are also organ and/or tissue transplant donors, pathology incidental findings may be relevant not (...) to family members, but to potential organ or tissue transplant recipients. This paper will describe the ethical implications of pathology incidental findings in the Genotype-Tissue Expression project, the process for developing a consensus approach as to if/when such findings should be returned, possible implications for other research projects collecting postmortem tissues and how the scenario encountered in GTEx fits into the larger return of results/incidental findings debate. (shrink)

We explore the crucial role of diagrams in scientific reasoning, especially reasoning directed at developing mechanistic explanations of biological phenomena. We offer a case study focusing on one research project that resulted in a published paper advancing a new understanding of the mechanism by which the central circadian oscillator in Synechococcus elongatus controls gene expression. By examining how the diagrams prepared for the paper developed over the course of multiple drafts, we show how the process of generating a new explanation (...) vitally involved the development and integration of multiple versions of different types of diagrams, and how reasoning about the mechanism proceeded in tandem with the development of the diagrams used to represent it. (shrink)

Shortages of life-saving medical resources caused by COVID-19 have prompted hospitals, healthcare systems, and governmentsto develop crisis standards of care, including 'triage protocols' to potentially ration medical supplies during the public health emergency. At the same time, the pandemic has highlighted and exacerbated racial, ethnic, and socioeconomic health disparities that together constitute a form of structural racism. These disparities pose a critical ethical challenge in developing fair triage systems that will maximize lives saved without perpetuating systemic inequities. Here we review (...) alternatives to 'utilitarian' triage, including first-come first-served, egalitarian, and prioritarian systems of allocating scarce medical resources. We assess the comparative advantages and disadvantages of these allocation schemes. Ultimately, we argue that while triage protocols should not exacerbate disparities, they are not an adequate mechanism for redressing systemic health inequities. Entrenched health disparities must be addressed through broader social change. (shrink)

The idea that the world is made of particles — little discrete, interacting objects that compose the material bodies of everyday experience — is a durable one. Following the advent of quantum theory, the idea was revised but not abandoned. It remains manifest in the explanatory language of physics, chemistry, and molecular biology. Aside from its durability, there is good reason for the scientific realist to embrace the particle interpretation: such a view can account for the prominent epistemic fact that (...) only limited knowledge of a portion of the material universe is needed in order to make reliable predictions about that portion. Thus, particle interpretations can support an abductive argument from the epistemic facts in favor of a realist reading of physical theory. However, any particle interpretation with this property is untenable. The empirical adequacy of modern particle theories requires adoption of a postulate known as permutation invariance — the claim that interchanging the role of two particles of the same kind in a dynamical state description results in a description of the identical state. It is the central claim of this essay that PI is incompatible with any particle interpretation strong enough to account for the epistemic facts. This incompatibility extends across all physical theories. To frame and motivate the inconsistency argument, I begin by fixing the relevant notion of particle. To single out those accounts of greatest appeal to the realist, I develop the logically weakest particle ontology that entails the epistemic fact that the world is piecewise predictable, an ontology I call ‘minimal atomism’. The entire series of scientific conceptions of the particle, from Newton’s mechanically interacting corpuscles to the ‘centers of force’ in classical field theories, all comport with MA. As long as PI is left out, even quantum mechanics can be viewed this way. To assess the impact of PI on this picture, I present a framework for rigorously connecting interpretations to physical theories. In particular, I represent MA as a set of formal conditions on the models of physical theories, the mathematical structures taken to represent states of the world. I also formulate PI — originally introduced as a postulate of non-relativistic quantum mechanics — in theory independent terms. With all of these pieces in hand, I am then able to present a proof of the inconsistency of PI and MA. In the second part of the essay, I survey responses to the inconsistency result open to the scientific realist. The two most plausible approaches involve abandoning particles in one way or another. The first alternative interpretation considered takes the property bearing objects of the world to be regions of space rather than particles. In this view, the properties once attributed to particles in quantum states are attributed instead to one or more regions of space. PI no longer obtains in this case, at least not as a statement about the permutation symmetry of property bearers. Rather, the new interpretation naturally imposes an analogous constraint on quantum states. The second major approach to evading the inconsistency result is to dispense with objects altogether. This is the recommendation of so-called ‘Ontic Structural Realism’. The central OSR thesis is that structure rather than entities are the basic ontological components of the world. OSR is intended to embrace the ‘miracle’ argument in favor of scientific realism while avoiding the pessimistic meta-induction. I demonstrate that one principal motivation for OSR based on the under-determination of interpretations in QM is actually dissolved by the incompatibility result. At the same time, I suggest reasons to think that OSR fares no better with respect to the pessimistic meta-induction than traditional realism does. Thus, while PI and MA may be incompatible, object ontologies remain the best option for the realist. (shrink)

The ability to learn the direction of causal relations is critical for understanding and acting in the world. We investigated how children learn causal directionality in situations in which the states of variables are temporally dependent (i.e., autocorrelated). In Experiment 1, children learned about causal direction by comparing the states of one variable before versus after an intervention on another variable. In Experiment 2, children reliably inferred causal directionality merely from observing how two variables change over time; they interpreted Y (...) changing without a change in X as evidence that Y does not influence X. Both of these strategies make sense if one believes the variables to be temporally dependent. We discuss the implications of these results for interpreting previous findings. More broadly, given that many real-world environments are characterized by temporal dependency, these results suggest strategies that children may use to learn the causal structure of their environments. (shrink)

One implication of Bell’s theorem is that there cannot in general be hidden variable models for quantum mechanics that both are noncontextual and retain the structure of a classical probability space. Thus, some hidden variable programs aim to retain noncontextuality at the cost of using a generalization of the Kolmogorov probability axioms. We generalize a theorem of Feintzeig to show that such programs are committed to the existence of a finite null cover for some quantum mechanical experiments, i.e., a finite (...) collection of probability zero events whose disjunction exhausts the space of experimental possibilities. (shrink)

The history of design arguments stretches back to before Aquinas, who claimed that things which lack intelligence nevertheless act for an end to achieve the best result. Although science has advanced to discredit this claim, it remains true that many biological systems display remarkable adaptations of means to ends. Versions of design arguments have persisted over the centuries and have culminated in theories that propose an intelligent designer of the universe. This volume is the only comprehensive survey of 2,000 years (...) of debate, drawing on both historical and modern literature to identify, clarify and assess critically the many forms of design argument for the existence of God. It provides a neutral, informative account of the topic from antiquity to Darwin, and includes concise primers on probability and cosmology. It will be of great value to upper-level undergraduates and graduates in philosophy of religion, theology, and philosophy of science. (shrink)

This review uses the excellent recent anthology, What Is Enough: Sufficiency, Justice, and Health, edited by Carina Fourie and Annette Rid, as a springboard for a discussion of a little-noticed problem for sufficientarian principles governing the distribution of health or health care. All sufficientarian principles must be assigned a scope: the set of individuals who are to be brought up to the level of sufficiency. When it comes to health and health care, sufficientarians will, rightly, want to reject broad scopes, (...) because they will entail that we are accountable for securing health care for, for example, wild animals. Unfortunately, any narrow scope will seem morally arbitrary, because it will imply that among all the individuals who could benefit from health care we are obligated to provide it only to some of them. But, I suggest here that such arbitrariness is no problem for narrow-scope sufficientarianism in health or health care as long as the principle is cast as a non-fundamental principle of public policy as opposed to a fundamental moral principle. (shrink)

The work of the contemporary French philosopher Jean-Luc Nancy has impacted across a range of disciplines. His writings on psychoanalysis, theology, art, culture and, of course, philosophy are now widely translated and much discussed. His L'Experience de la Liberte is considered to be one of the landmarks of contemporary continental philosophy. Jean-Luc Nancy and the Future of Philosophy is the first genuine introduction to Nancy's ideas and a clear and succinct appraisal of a burgeoning reputation. The book summarises topically the (...) primary conceptual areas of Nancy's thought and explores its relevance for contemporary issues like nationalism, racism and media rights. Nancy's indebtedness to Nietzsche, Heidegger, and Bataille is examined as well as how his ideas compare to those of his contemporary continental thinkers. Three major areas of Nancy's work are emphasised: freedom and morality; community and politics; and arts and the media. The reader is guided through a chosen theme without being lost in a welter of allusive language, jargon is avoided where possible and when unavoidable it is clearly explained. The book concludes with a new interview with Nancy, which discusses the future of philosophy. The book will be an important addition to the readings lists for courses on contemporary continental thought and political philosophy. (shrink)

Middle childhood, the period from 6 to 12 years of age, is defined socially by increasing autonomy and emotional regulation, somatically by the development of anatomical structures for subsistence, and endocrinologically by adrenarche, the adrenal production of dehydroepiandrosterone (DHEA). Here I suggest that DHEA plays a key role in the coordinated development of the brain and body beginning with middle childhood, via energetic allocation. I argue that with adrenarche, increasing levels of circulating DHEA act to down-regulate the release of glucose (...) into circulation and hence limit the supply of glucose which is needed by the brain for synaptogenesis. Furthermore, I suggest the antioxidant properties of DHEA may be important in maintaining synaptic plasticity throughout middle childhood within slow-developing areas of the cortex, including the insula, thamalus, and anterior cingulate cortex. In addition, DHEA may play a role in the development of body odor as a reliable social signal of behavioral changes associated with middle childhood. (shrink)

Despite their centrality to the scientific enterprise, both the nature of scientific variables and their relation to inductive inference remain obscure. I suggest that scientific variables should be viewed as equivalence classes of sets of physical states mapped to representations in a structure preserving fashion, and argue that most scientific variables introduced to expand the degrees of freedom in terms of which we describe the world can be seen as products of an algorithmic inductive inference first identified by William W. (...) Rozeboom. This inference algorithm depends upon a notion of natural kind previously left unexplicated. By appealing to dynamical kinds—equivalence classes of causal system characterized by the interventions which commute with their time evolution—to fill this gap, we attain a complete algorithm. I demonstrate the efficacy of this algorithm in a series of experiments involving the percolation of water through granular soils that result in the induction of three novel variables. Finally, I argue that variables obtained through this sort of inductive inference are guaranteed to satisfy a variety of norms that in turn suit them for use in further scientific inferences. (shrink)