Technologies for enhancement of the human body historically have taken the form of an apparatus: a technological device inserted in, or appended to, the human body. The margins of these devices were clearly discernible and materially circumscribed, allowing the distinction between the corporeality of the human body and the “machine” to remain both ontologically and materially secure. This dualism has performed some important work for human rights theorists, regulators, and policy makers, enabling each to imagine they can establish where the (...) human ends and the other begins. New regenerative products such as Infuse™ and Amplify™ subsist, as animal-derived scaffolds seeded with growth hormone implanted within a prosthetic device. They are much more materially complex, and their identities thus remain open to contestation. Following Lochlann Jain’s 2006 work, I thus attend closely to their social lives, particularly the stories that are told about them and how these are employed to construct understandings of what kind of a phenomenon they are: systemic drug, biologic, or combinatorial medical device. The significance of this classificatory project is revealed in the final section of this paper, which explores how these stories shape understandings of “product failure,” liability, and causation when such products overflow their material and ontological categorization and their recipients become disturbingly “more than human.”. (shrink)

One of the first envatted brains, the most cyborgian element of J. D. Bernal’s 1929 futuristic manifesto, The world, the flesh and the the devil, proposed a technological solution to the dreary certainty of mortality. In Bernal’s scenario the brain is maintained in an ‘out of body’ but ‘like-body’ environment—in a bath of cerebral–spinal fluid held at constant body temperature. In reality, acquiring prospective immortality requires access to very different technologies—those that allow human organs and tissues to be preserved in (...) a quite ‘inhuman’ life-world—the cryogenic storage chamber. Like Bernal, today’s cryonicists consider that immortality can be secured through preservation of the brain alone. In this article I trace attempts to preserve or suspend life, and especially brain function, through the application of new ‘technologies of immortality’. Drawing together historical information on the development of refrigeration, cryopreservation, transplantation, and nanotechnologies, I explore the uneasy relationship between cryonics and the technology on which it depends for its success—cryogenics. In so doing, I argue that the ability to successfully realize the science fiction fantasy of human immortality will rest on a moral and scientific parasitism: the capacity to use the biotechnological artifacts or proxies—cryogenically preserved brains, archived brains, tissues, and immortalized cell lines—derived from the dead, in order to prolong life. (shrink)

This article explores a number of questions about the relationship between intimacy and research that were bought into sharp focus for me by a disturbing event: my unexpected encounter with Iris Murdoch's archived brain. In considering how very intimate experiences such as these are both constructed and narrated to wider audiences, I begin by exploring the nature of intimacy itself. Here I argue that intimacy is the product of not only social but spatial relations, relations that may, in contrast to (...) popular conceptions, be `stretched out' to create what I call here `distributed spaces of intimacy'. In exploring the role that material artefacts can play as objects that create essential points of interface between individuals and communities that are geographically and socially distant, I also draw attention to the necessarily partial and relational nature of intimacy. In the final section of the article I turn to consider the impact that intensely personal experiences may have on research methodologies and the vexatious question of how, if at all, it is possible to speak of, or report them, without transgressing important social, moral and ethical conventions. (shrink)

While providing a welcome and timely revision of the now outdated Human Tissue Act of 1961, the newly introduced Human Tissue Bill of 2004 contains a number of anomalies in its drafting that threaten to undermine its effectiveness in practice. Two examples: the first relating to the status of 'remnant or waste' tissue and the second relating to the status and use of artefacts created from collected tissue are here employed to illustrate some of the definitional and categorical inconsistencies that (...) are evident in the Bill. Having identified these, the paper then provides an analysis of how these inconsistencies may act to severely constrain the ways in which retained tissue may be lawfully employed in biomedical research and to confuse questions of who may, or may not, have formally recognised interests in types of processed human tissue. (shrink)