This is a volume of twelve essays concerning the fundamental tension in personalised medicine between individual choice and the common good.

This article offers a legal-ethical analysis of recent UK and Dutch proposals to regulate surrogacy proactively through a national system of pre-conception authorization of surrogacy agreements. Wi...

This edited volume covers new ground by bringing together perspectives from symbolic legislation theory on the one hand, and from biolaw and bioethics on the other hand. Symbolic legislation has a bad name. It usually refers to instances of legislation which are ineffective and that serve other political and social goals than the goals officially stated. Recently, a more positive notion of symbolic legislation has emerged in legislative theory. From this perspective, symbolic legislation is regarded as a positive alternative to (...) the more traditional, top-down legislative approach. The legislature no longer merely issues commands backed up with severe sanctions, as in instrumental legislation. Instead, lawmakers provide open and aspirational norms that are meant to change behavior not by means of threat, but indirectly, through debate and social interaction. Since the 1990s, biomedical developments have revived discussions on symbolic legislation. One of the reasons is that biomedical legislation touches on deep-rooted, symbolic-cultural representations of the biological aspects of human life. Moreover, as it is often impossible to reach consensus on these controversial questions, legislators have sought alternative ways to develop legal frameworks. Consequently, communicative and interactive approaches to legislation are prominent within the governance of medical biotechnology. The symbolic dimensions of biolaw are often overlooked. Yet, it is clear that the symbolic is at the heart of many legal-political debates on bioethical questions. Since the rise of biomedical technologies, human body materials have acquired a scientific, medical and even commercial value. These new approaches, which radically question existing legal symbolizations of the human body, raise the question whether and how the law should continue to reflect symbolic values and meanings. Moreover, how can we decide what these symbolic values are, given the fact that we live in a pluralistic society? (shrink)

In the case of surrogacy, it is not new biotechnologies themselves that have challenged well-established principles in law and ethics, but rather political and social phenomena such as commodification of women’s reproductive tissue and labour, demands to allow new ways of forming families and (before Covid-19, at least) the comparative ease of international travel that enabled cross-border surrogacy to develop into a market valued at up to $2 billion annually in India alone as of 2016 (Dickenson 2016, citing an estimate (...) from The Indian National Commission for Women). This phenomenon stands the usual truth on its head: it is not new technologies but new pressures that have challenged the existing law and ethics of surrogate motherhood. (shrink)

Over 30 million people worldwide have taken a commercial at-home DNA test, because they were interested in their genetic ancestry, disease predisposition or inherited traits. Yet, these consumer DNA data are also increasingly used for a very different purpose: to identify suspects in criminal investigations. By matching a suspect’s DNA with DNA from a suspect’s distant relatives who have taken a commercial at-home DNA test, law enforcement can zero in on a perpetrator. Such forensic use of consumer DNA data has (...) been performed in over 200 criminal investigations. However, this practice of so-called investigative genetic genealogy raises ethical concerns. In this paper, we aim to broaden the bioethical analysis on IGG by showing the limitations of an individual-based model. We discuss two concerns central in the debate: privacy and informed consent. However, we argue that IGG raises pressing ethical concerns that extend beyond these individual-focused issues. The very nature of the genetic information entails that relatives may also be affected by the individual customer’s choices. In this respect, we explore to what extent the ethical approach in the biomedical genetic context on consent and consequences for relatives can be helpful for the debate on IGG. We argue that an individual-based model has significant limitations in an IGG context. The ethical debate is further complicated by the international, transgenerational and commercial nature of IGG. We conclude that IGG should not only be approached as an individual but also—and perhaps primarily—as a collective issue. There are no data in this work. (shrink)

Millions of human biological samples are stored worldwide for medical research or treatment purposes. These biospecimens are of enormous potential value to law enforcement as DNA profiles can be obtained from these samples. However, forensic use of such biospecimens raises a number of ethical questions. This article aims to explore ethical issues of using human bodily material in medical biobanks for crime investigation and prosecution purposes. Concerns about confidentiality, trust, autonomy and justice will be discussed. We explore how to balance (...) these concerns against the importance of crime solving. Relevant case examples of forensic use of medical biobanks show that requests by law enforcement to access biobanks are handled in disparate ways. We identify some core ethical issues and conclude that further research on these issues is needed to provide ethical guidance. (shrink)

Not a single day goes by without some news about personalized medicine, especially in its genomic context (precision medicine). In tandem with the scientific excitement, however, come the cautionary notes. These include worries about Big Brother surveillance, concerns about the impact of genomic results on the psychosocial well‐being of patients and research subjects, and attention to issues of social and distributive justice. Personalised Medicine, Individual Choice and the Common Good, coedited by Britta van Beers, Sigrid Sterckx, and Donna (...) Dickenson, falls squarely into this discourse with an aim to “fuel and stimulate the debate about personalised medicine and enable its participants to come to a more balanced understanding of the interests and values at stake.” At its core, the book laments the shift from “We Medicine” to “Me Medicine,” with ostensibly all authors highlighting that, on balance, the costs associated with “Me Medicine” far outweigh the benefits. This is both a strength and a weakness of the book. (shrink)

In the Australian context, all teachers are obliged, in accordance with the national curriculum, to engage students in critical and creative thinking in the classroom. Yet teachers often wonder ‘How do we facilitate the development of (critical and creative) thinking skills in our students?’ In our specific local context, a large-scale community consultation highlighted a need for a thorough, concerted strategic approach in relation to this obligation. In this paper we spell out our response to this need: the establishment of (...) a Centre for Critical Thinking and Ethics to implement a two-pronged strategic approach. It is our contention that the best way to cater for students’ growth in critical and creative thinking is to combine deliberative use of explicit critical thinking materials with the norms/tools/activities and strategies of the Philosophy in Schools pedagogy. Our innovation consists primarily in our 'detached' and 'embedded' approaches to critical thinking at Newington College. We aim to contribute to the ongoing discussion of best practice in critical and creative thinking, to improve capacity both in and beyond our own school. (shrink)

Metaphors abound in descriptions of the COVID-19 pandemic: it is described, among other things, as a war, a flood, and a marathon. However, not all metaphors may resonate equally well with members...

Doing and Being confronts the problem of how to understand two central concepts of Aristotle's philosophy: energeia and dunamis. While these terms seem ambiguous between actuality/potentiality and activity/capacity, Aristotle did not intend them to be so. Through a careful and detailed reading of Metaphysics Theta, Beere argues that we can solve the problem by rejecting both "actuality" and "activity" as translations of energeia, and by working out an analogical conception of energeia. This approach enables Beere to discern a hitherto unnoticed (...) connection between Plato's Sophist and Aristotle's Metaphysics Theta, and to give satisfying interpretations of the major claims that Aristotle makes in Metaphysics Theta, the claim that energeia is prior in being to capacity and the claim that any eternal principle must be perfectly good. (shrink)

This chapter mixes memory and desire. The memory is of how science in general and ethology in particular were conceived in the tough-minded, positivistic tradition in which I was brought up as a student. The desire is for the possibility that, with the questioning of this positivistic tradition in general and the emergence of cognitive ethology in particular, issues concerning animal mentality and intentionality, which the older views kept in the dark, might now be looked at in a new light. (...) The philosophical developments critical of the older positivism bear on these issues in ways that are both encouraging and challenging to cognitive ethology. In what follows I first sketch some of the history of ideas relevant to the transition from classical ethology to cognitive ethology, and then discuss some of the philosophical problems with which I think current attempts to be useful anthropomorphic about animal behavior have to contend. (shrink)

Considering two recent trends in the Humanities – the cultural turn and the increase of critical sociohistorical reflections on a global level – in this paper it should be looked at their influences especially on philosophy. One of these influences can be located in the emergence of “intercultural philosophy” since the 1990s which calls for a reorientation of philosophy in general. Regarding mainly one of the favored methods, the polylogue, it is important to take into account the postcolonial perspective, too. (...) For such an interculturally and postcolonially motivated approach there are two tasks which are highly relevant: 1) the deconstruction of history in direction towards a new critical historiography and 2) the due reflection of crucial philosophical concepts and categories in direction towards a conceptual decolonization. Mainly the latter, in my opinion, marks a necessary and already overdue project for rethinking the philosophical vocabulary and for overcoming its colonial impact. Perhaps this may finally become a really intercultural philosophical project in which philosophers engage wherever they may be from. (shrink)

How do we switch between “playing along” and treating robots as technical agents? We propose interaction breakdowns to help solve this “social artifact puzzle”: Breaks cause changes from fluid interaction to explicit reasoning and interaction with the raw artifact. These changes are closely linked to understanding the technical architecture and could be used to design better human–robot interaction (HRI).

Neuroscience investigations of emotional influences on social cognition have been dominated by the somatic marker hypothesis and dual-process theories. Taken together, these lines of inquiry have not provided strong evidence that emotional influences on social cognition rely on neural systems which code for bodily signals of arousal nor distinguish emotional reasoning from other modes of reasoning. Recent findings raise the possibility that emotionally influenced social cognition relies on two stages of neural changes: once when emotion is elicited and a different (...) set of changes at the time of social cognitive judgment. These findings suggest that affect infusion models may be a fruitful framework for bridging neuroscience and psychological understanding of the role of emotion in social cognition. (shrink)

Should high‐income countries engage in solar geoengineering research and possible deployment? On the assumption that the speed of the energy transition will be insufficient to abate catastrophic climate impacts, research into solar geoengineering begins to look like a technically and socially feasible route to mitigate such impacts. But on the assumption that a rapid and relatively just energy transition is still within the realm of political possibility, research into solar geoengineering looks more like an ideological tool designed to divert time (...) and resources from less risky climate solutions. At the heart of debates over solar geoengineering, then, is disagreement over what political actors can be expected to do in the future. In this article, I argue that both objectors to and proponents of solar geoengineering research often make background assumptions regarding expected future actions that are either (a) inaccurate or (b) inconsistent. I propose an account of expected future actions that avoids these problems and sketch what the debate over solar geoengineering looks like with these assumptions in place. (shrink)

Medical imaging has provided insight into the living body that were not possible beforehand. With these methods a revolution in medical diagnosis and biomedical research has begun. Problematic aspects on the other hand are arising from the highly constructive properties of image production, which use complicated physical and physiological effects. Images are established via highly complicated combinations of technology and contingently chosen mathematical and algorithmic solutions. In addition, image construction follows properties of the human visual and cognitive system to allow (...) for the discrimination of the desired categories. It is no wonder that the visualizations referring to the body also show effects which have no physiological correlation within the body. Still such images are often used as if they were one-to-one correlates of the body. This has impacts, e.g. for their use as standardizing instances, resulting in new definitions of the normed healthy body, sickness or pathologies, maleness and femaleness and in determinisms as opposed to the brain's plasticity and variability, both in time and space, inter- as well as intra-individually. (shrink)

Suppose the present generation leaves future ones with a world depleted of all the natural resources required for many valuable human pursuits. Has the present generation acted unjustly? According to contemporary theories of liberal egalitarian intragenerational and intergenerational justice, the answer, it appears, is no. The explanation for this verdict lies in the liberal commitment to remaining neutral between different ways of life: many value-laden environ- mental sites and species are not an all-purpose means to any reasonable human end and (...) so their existence is not directly relevant in an assessment of whether justice obtains. Against this view, I argue that a commitment to neutrality and its underlying justification – the idea that individuals should be equipped to live lives of their own design – in fact supports the opposite conclusion. If justice requires that citizens can pursue whatever way of life they do or might value, then it will also demand the continued existence of the natural resources necessary for those pursuits. (shrink)

Die Kategorie des Menschseins wird aufgrund wechselnder Wissensbestände und Orientierungskrisen immer wieder neu bestimmt. Das Ästhetische ist damit eng verbunden. 'Aisthesis' ist erstens eine Form der sinnlichen und empfindenden Wahrnehmung, ein vorrationaler 'way of worldmaking' (Nelson Goodman), der den Bezug des Menschen zu sich und seiner Welt moduliert. Ästhetische Vorstellungen grundieren zweitens aber auch die Idee des Humanen und die Normen menschlicher Handlungs-weisen. Und drittens sind ästhetische Erkenntnis- und Ausdrucksformen Teil eines 'selbstgesponnenen Bedeutungsgewebes' (Clifford Geertz) der Kultur, das die Grenzen (...) und das 'Andere' des Menschen bestimmt. Der interdisziplinäre Sammelband vereint aus verschiedenen Fächern und Forschungsperspektiven heraus Einblicke in die Wechselwirkungen zwischen anthropologischen Fragestellungen und ästhetischen Formationen. Mit Beiträgen von Horst Bredekamp, Steffen Martus, Martin Seel, Christoph Wulf, Elisabeth Timm u.a. (shrink)

A scholarly edition of The Clarendon Edition of the Works of John Locke: Correspondence: Letters 1242-1701 by E. S. de Beer. The edition presents an authoritative text, together with an introduction, commentary notes, and scholarly apparatus.

E. S. de Beer>'s eight-volume edition of the correspondence of John Locke is a classic of modern scholarship. The intellectual range of the correspondence is universal, covering philosophy, theology, medicine, history, geography, economics, law, politics, travel and botany. This first volume covers the years 1650 to 1679.

Low-Beer, a lawyer, Canadian federal politician, and poet, examines judgment as exercise, identifying the critical elements of the exercise of judgment and relating them to cognitive functions. He argues against relegating judgement to the realm of the subjective, and looks at the extent to which it can be learned and its reciprocal relationship to character. He concludes that the exercise of judgment is a defining characteristic of professionalism in the courts, the professions, politics, and commerce. For scholars and lay readers. (...) Annotation copyright by Book News, Inc., Portland, OR. (shrink)

A scholarly edition of The Clarendon Edition of the Works of John Locke: Correspondence: Letters 1702-2198 by E. S. de Beer. The edition presents an authoritative text, together with an introduction, commentary notes, and scholarly apparatus.

There has been considerable debate in the literature about the relative merits of information processing versus dynamical approaches to understanding cognitive processes. In this article, we explore the relationship between these two styles of explanation using a model agent evolved to solve a relational categorization task. Specifically, we separately analyze the operation of this agent using the mathematical tools of information theory and dynamical systems theory. Information-theoretic analysis reveals how task-relevant information flows through the system to be combined into a (...) categorization decision. Dynamical analysis reveals the key geometrical and temporal interrelationships underlying the categorization decision. Finally, we propose a framework for directly relating these two different styles of explanation and discuss the possible implications of our analysis for some of the ongoing debates in cognitive science. (shrink)

Der Begriff des Subjekts meint im Kern das Erkenntnissubjekt. Damit wird vornehmlich auf eine kognitive Dimension verwiesen, die sich mit Termini wie Vernunft oder Rationalität konnotieren lässt. Mit dem Blick auf die Ästhetik lässt sich dies durch Formen der Sinnlichkeit und der Kreativität ergänzen. Die „Ästhetik des Subjekts“ zielt dabei auf eine allgemeine Subjekttheorie, die als Kritische Theorie angelegt sein soll. In diesem Kontext wird die ästhetische Erfahrung zu einem Baustein der Emanzipation.