On the Origin of Objects is the culmination of Brian Cantwell Smith's decade-long investigation into the philosophical and metaphysical foundations of computation, artificial intelligence, and cognitive science. Based on a sustained critique of the formal tradition that underlies the reigning views, he presents an argument for an embedded, participatory, "irreductionist," metaphysical alternative. Smith seeks nothing less than to revise our understanding not only of the machines we build but also of the world with which they interact. Smith's ambitious project begins (...) as a search for a comprehensive theory of computation, able to do empirical justice to practice and conceptual justice to the computational theory of mind. A rigorous commitment to these two criteria ultimately leads him to recommend a radical overhaul of our traditional conception of metaphysics. Everything that exists -- objects, properties, life, practice -- lies Smith claims in the "middle distance," an intermediate realm of partial engagement with and partial separation from, the enveloping world. Patterns of separation and engagement are taken to underlie a single notion unifying representation and ontology: that of subjects' "registration" of the world around them. Along the way, Smith offers many fascinating ideas: the distinction between particularity and individuality, the methodological notion of an "inscription error," an argument that there are no individuals within physics, various deconstructions of the type-instance distinction, an analysis of formality as overly disconnected ("discreteness run amok"), a conception of the boundaries of objects as properties of unruly interactions between objects and subjects, an argument for the theoretical centrality of reference preservation, and a theatrical, acrobatic metaphor for the contortions involved in the preservation of reference and resultant stabilization of objects. Sidebars and diagrams throughout the book help clarify and guide Smith's highly original and compelling argument. A Bradford Book. (shrink)
BackgroundThe U.S. Food and Drug Administration traditionally has kept confidential significant amounts of information relevant to the approval or non-approval of specific drugs, devices, and biologics and about the regulatory status of such medical products in FDA’s pipeline.ObjectiveTo develop practical recommendations for FDA to improve its transparency to the public that FDA could implement by rulemaking or other regulatory processes without further congressional authorization. These recommendations would build on the work of FDA’s Transparency Task Force in 2010.MethodsIn 2016-2017, we convened (...) a team of academic faculty from Harvard Medical School, Brigham and Women’s Hospital, Yale Medical School, Yale Law School, and Johns Hopkins Bloomberg School of Public Health to develop recommendations through an iterative process of reviewing FDA’s practices, considering the legal and policy constraints on FDA in expanding transparency, and obtaining insights from independent observers of FDA.ResultsThe team developed 18 specific recommendations for improving FDA’s transparency to the public. FDA could adopt all these recommendations without further congressional action.FundingThe development of the Blueprint for Transparency at the U.S. Food and Drug Administration was funded by the Laura and John Arnold Foundation. (shrink)
The belief that automated technologies will have a salutary effect on war goes back to the late nineteenth century. In 1898, at Madison Square Garden, Nikola Tesla famously showcased the first radi...
When Huxley quotes the famous Jefferson line in Brave New World Revisited—"If a nation expects to be ignorant and free... it expects what never was and never will be"2—there is something, on the face, humorously explicit to it. The state of civilization the brave new world is in seems to speak directly to this point. Brave new worlders are ignorant and conspicuously not free; they "[like] what [they've] got to do"3 because they have been decanted and conditioned by the corporate (...) government, the World State. This cursory assessment, however, obscures another possibility, one that touches on the satirical poignancy and relevance of. (shrink)
Of the two purposes of this article, the first is to show that the prohibition against intentionally targeting civilians is poorly suited to the current techno-rational landscape of warfare. Sophis...
Adrian Johnston is well known for his work at the intersection of Lacanian psychoanalysis, German idealism, contemporary French philosophy and most recently cognitive neuroscience. In the context of the current issue, Johnston represents the most complete development of a contemporary theory of Transcendental Materialism. In the following interview we explore both the implications of Johnston’s previous work, as well as the directions his most recent projects are taking.
Restraining the violence of war is difficult under the best of circumstances. In their observations on the French Revolution and Napoleonic Wars, Edmund Burke and Carl von Clausewitz consider the peculiar violence of wars fought for abstract and world-transformative goals. While the beliefs that animated those wars have faded, in this essay we argue that Burke and Clausewitz offer insight into the ways that modern political violence becomes unmoored from limitation and restraint and that their arguments show a surprising unity (...) between the concerns of realists and just war theorists about the limitation of war. (shrink)
Aircraft with increasingly high performance were important to the war effort in World War II. Changes in technology allowed aircraft to reach faster speeds and to complete missions at higher altitudes. With these changes came new obstacles for pilots who had to tolerate these stresses. Of primary concern to the U.S. War Department was the loss of consciousness that often occurred with high-speed maneuvers and especially during pull-up after dive-bombing missions. In some cases, pilots would experience up to 9G of (...) force during rapid ascent, much more than the 6G threshold that typically leads to loss of consciousness. In 1941, a research team in Red Wing, MN, proposed experiments to elucidate the mechanism .. (shrink)
The influence of physician judgment on the disclosure, competency, understanding, voluntariness, and decision aspects of informed consent for bone marrow transplantation are described. Ethical conflicts which arise from the amount and complexity of the information to be disclosed and from the barriers of limited time, patient anxiety and lack of prior relationship between patient and physician are discussed. The role of the referring physician in the decision-making is considered. Special ethical issues which arise with use of healthy related bone marrow (...) donors are discussed, as is the physician's discretion in raising questions of competency. It is concluded that in this setting, regardless of the theoretical goals of the physician, patients appear to utilize informed consent discussions to assess their capacity to trust the physician rather than as a time to weigh the large amount of relevant data. The conscientious physician best serves the patient with recommendation of the best medical alternative rather than with attempts to remain neutral. (shrink)
Anxiety concerning the decline and fall of civilization appears throughout Walker Percy’s body of work. Smith argues that what sets Percy’s account of this issue apart from others rests in his preoccupation not so much with depicting actual disaster for what it might tell us about human nature, politics, or our souls, but rather, with his focus on the end of our society as a clue that might help explain our predicament. Percy saw his role as reading the signs of (...) our spiritual and social disorders, and rendering them intelligible to an audience that increasingly possessed a language inadequate to understanding the situation. Percy’s analysis of our attitudes toward catastrophe, disaster, war, and the end of civilization proves a fertile ground for exploring the fault lines in our social and political life. (shrink)
