Recent experimental data from proteomics and genomics are interpreted here in ways that challenge the predominant viewpoint in biology according to which the four evolutionary processes, including mutation, recombination, natural selection and genetic drift, are sufficient to explain the origination of species. The predominant viewpoint appears incompatible with the finding that the sequenced genome of each species contains hundreds, or even thousands, of unique genes - the genes that are not shared with any other species. These unique genes and proteins, (...) singletons, define the very character of every species. Moreover, the distribution of protein families from the sequenced genomes indicates that the complexity of genomes grows in a manner different from that of self-organizing networks: the dominance of singletons leads to the conclusion that in living organisms a most unlikely phenomenon can be the most common one. In order to provide proper rationale for these conclusions related to the singletons, the paper first treats the frequency of functional proteins among random sequences, followed by a discussion on the protein structure space, and it ends by questioning the idea that protein domains represent conserved units of evolution. (shrink)

This book examines the wide-ranging implications for historical research of the view that everything is physical and that no immaterial entities, forces, or phenomena exist. It presents the consequences of materialism for our understanding of the historical past, including the rejection of postmodernist perspectives on history.

Dans les années 1760, l'atelier du baron d'Holbach est, avec Ferney au temps de Voltaire, le principal lieu de diffusion des idées hétérodoxes qui permettent la radicalisation des Lumières en France. L'activité de traduction d'Holbach, plus importante en quantité que son activité d'auteur, est étudiée ici pour la première fois de manière systématique. En comparant les ouvrages clandestins traduits et publiés par Holbach avec leurs vrais ou prétendus originaux (majoritairement anglais), Mladen Kozul analyse les manipulations énonciatives, thématiques et éditoriales qu'Holbach (...) opère dans les textes anglais pour en légitimer le discours et les transformer en livres clandestins français. Il montre qu'Holbach, fidèle aux procédés d'une culture rhétorique qui brasse et recycle textes et discours, s'appuie sur les stratégies des encyclopédistes qu'il perfectionne en employant les méthodes de la librairie clandestine. Les textes traduits par Holbach orientent d'une manière décisive la perception qu'a le public des correspondances entre les idées des Lumières en France et celles provenant d'autres cultures de l'Europe occidentale, et notamment d'Angleterre. Les figures d'auteurs anglais qui se dégagent du livre clandestin apparaissent comme des constructions qui installent, aux yeux du lecteur français, le mirage d'un front philosophique transculturel radical, uni et solidaire. Les pratiques du baron nous permettent ainsi d'interroger le rapport complexe du public cultivé des Lumières à l'altérité culturelle. En repensant les notions de traduction et d'auteur, Mladen Kozul invite à voir en Holbach l'inventeur d'une des premières manipulations médiatiques d'envergure en Occident. (shrink)

U ovom članku daje se prikaz hrvatskih sljedbenika teorije relativnosti iz redova matematičara, fizičara, prirodoslovaca i tehničara. Istraživanje se odnosi na sveučilišna predavanja, seminare, znanstvene i popularne članke, prevedene znanstvene, stručne i popularne knjige i ostale publikacije u svezi s Einsteinovom teorijom relativnosti. Prikaz rezultata istraživanja iznosi se povijesnim redoslijedom s kratkim osvrtom na značenje i osnovne biografske podatke sljedbenikâ teorije relativnosti kod nas.Dieser Artikel gibt einen Űberblick der kroatischen Anhänger der Relativitätstheorie aus denReihen der Mathematiker, Physiker, Naturwissenschaftler und Techniker. (...) Die Untersuchungberichtet über Vorlesungen an Universitäten, wissenschaftliche und populäre Artikel, Übersetzungenwissenschaftlicher und populärerBücher sowie übrige Publikationen in VerbindungmitEinsteinsRelativitätstheorie. Die jeweiligen Veranstaltungenund Publikationen werdenin derReihenfolgeihresgeschichtlichen Erscheinens aufgeführt und sind versehen mit einem kurzenKommentarzu ihrerBedeutung sowie mit wesentlichen biografische Angabenzu den Anhängernder Relativitätstheorie hierzulande. (shrink)

In recent decades, a number of authors have relied on the multiple realizability argument to reject methodological individualism. In this article, I argue that this strategy results in serious difficulties and makes it impossible to identify social entities and phenomena.

Introduction -- Plato -- Aristotle -- The rise of modernity -- Immanuel Kant -- Romanticism and historicism -- Phenomenology and hermeneutics -- Philosophes and philosophers -- Analytic philosophy -- Conclusion.

The work of the Paduan Aristotelian philosopher Iacopo Zabarella (1533–1589) has attracted the attention of historians of philosophy mainly for his contributions to logic, scientific methodology and because of his possible influence on Galileo. At the same time, Zabarella's views on Aristotelian psychology have been little studied so far; even those historians of Renaissance philosophy who have discussed them, have based their analysis mainly on the psychological essays included in Zabarella's De rebus naturalibus , but have avoided Zabarella's commentary on (...) Aristotle's De anima . This has led to an inaccurate, but widespread, understanding of Zabarella's views. The intention of this article is to provide a systematic analysis of Zabarella's arguments about the (im)mortality of the soul in the context of Aristotelian psychology. Zabarella's view that the soul is mortal according to Aristotle is remarkable for his time, while his elaboration of this position is far more comprehensive than that of Pietro Pomponazzi, the other significant Renaissance thinker who shared the same view. (shrink)