Over the last two decades, network-focused approaches have become highly popular in diverse fields of biology, including neuroscience, ecology, molecular biology and genetics. While the network approach continues to grow very rapidly, some of its conceptual and methodological aspects still require a programmatic foundation. This challenge particularly concerns the question of whether a generalized account of explanatory, organisational and descriptive levels of networks can be applied universally across biological sciences. Consequently, the central focus of this theme issue will be on (...) the definition, motivation and application of key concepts in biological network science, such as levels, hierarchies, and explanatory directionality. A unification will be achieved by formulating norms for delimiting the distinctively network-topological class of explanations that connect general as well as very specific biological research questions. The impact of this theme issue is broad and encompassing, as it is highly interdisciplinary and opens a uniquely normative perspective on the foundational aspects of network-based explanations and modelling. This theme issue is intended to become a landmark publication for practical research as well as funding policy decisions, by unifying network approaches in biological sciences in terms of fundamental concepts and informing the public understanding of the network science. (shrink)

In this issue of The Journal of Clinical Ethics, we offer a variety of perspectives on the moral and medical responsibilities of professionals with regard to a woman’s choice of where she will birth her baby. The articles in this special issue focus on place of birth, but they have larger resonance for clinicians whose decisions about providing the best possible care require them to sort through evidence, consider their own possible biases and the limitations of their training, and balance (...) the wishes of their patients with the demands of colleagues, hospitals, and insurers. The articles published in this special issue of The Journal of Clinical Ethics will help those who wrestle with such dilemmas in everyday clinical decision making. (shrink)

We provide three innovations to recent debates about whether topological or “network” explanations are a species of mechanistic explanation. First, we more precisely characterize the requirement that all topological explanations are mechanistic explanations and show scientific practice to belie such a requirement. Second, we provide an account that unifies mechanistic and non-mechanistic topological explanations, thereby enriching both the mechanist and autonomist programs by highlighting when and where topological explanations are mechanistic. Third, we defend this view against some powerful mechanist objections. (...) We conclude from this that topological explanations are autonomous from their mechanistic counterparts. (shrink)

This paper discusses three research perspectives on political culture, civic culture and citizenship: the classic approach of Almond and Verba; contemporary analyses of citizenship referring to the book Civic Culture by Almond and Verba and oriented to the empirical description of social reality; and theoretical analyses of new relational sociology, oriented to the ontology and epistemology of social reality. The authors’ analysis leads to two conclusions. Firstly, it is necessary to combine these three approaches – relational social theory with empirical (...) analyses departing from methodological individualism. This requires conducting an empirical analysis, where the basic ‘analytical units’ – of collection, interpretation and generalization of data – are not separate but combined by relations and networks within which people act. Secondly, Edmund Wnuk-Lipiński’s statements are the best starting point for conducting such a new research programme. What is decisive is his systematic, theoretical interest in contemporary agency theories and relationality of citizenship, combined with innovative application of quantitative methods. (shrink)

The existence of the obligation to follow rules in sport is widely accepted, but there are only a few studies that provide accounts that justify it. Building upon Wolff's challenge to traditional political theories, this study proposes a theory that limits the level of normativity to which participants in sport contests are bound in an effort to maximize their autonomy. Instead of constructing a unitary theory of obligations to follow sport rules, a pluralistic account is offered, one that allows for (...) multiple sources of normativity, thus augmenting the freedom of communities to play games according to their values. (shrink)

In this paper, I present a general theory of topological explanations, and illustrate its fruitfulness by showing how it accounts for explanatory asymmetry. My argument is developed in three steps. In the first step, I show what it is for some topological property A to explain some physical or dynamical property B. Based on that, I derive three key criteria of successful topological explanations: a criterion concerning the facticity of topological explanations, i.e. what makes it true of a particular system; (...) a criterion for describing counterfactual dependencies in two explanatory modes, i.e. the vertical and the horizontal; and, finally, a third perspectival one that tells us when to use the vertical and when to use the horizontal mode. In the second step, I show how this general theory of topological explanations accounts for explanatory asymmetry in both the vertical and horizontal explanatory modes. Finally, in the third step, I argue that this theory is universally applicable across biological sciences, which helps to unify essential concepts of biological networks. (shrink)

This chapter provides a systematic overview of topological explanations in the philosophy of science literature. It does so by presenting an account of topological explanation that I (Kostić and Khalifa 2021; Kostić 2020a; 2020b; 2018) have developed in other publications and then comparing this account to other accounts of topological explanation. Finally, this appraisal is opinionated because it highlights some problems in alternative accounts of topological explanations, and also it outlines responses to some of the main criticisms raised by the (...) so-called new mechanists. (shrink)

Este artículo analiza la poesía de Leonel Lienlaf, poeta mapuche, desde una óptica ecocrítica. Para ello, se toman varias poesías del poemario Se ha despertado el ave de mi corazón (autotraducidas al español por el autor) con el fin de subrayar la importancia de la relación hombre-naturaleza. La dimensión simbólica utilizada por el autor se conecta directamente con la dimensión etnocultural del pueblo mapuche que, si bien no es el objeto principal del análisis, será igualmente importante considerarla. El artículo quiere (...) destacar el diálogo con la naturaleza queLienlaf pone de manifiesto en sus poesías y que se convierte, en última instancia, en una coexistencia con el medio ambiente. (shrink)

Modal constitution theory is one of the most influential solutions to the paradoxes of coincidence, and the problem of personal identity. It rests on three fundamental premises: common-sense objects exist; sometimes objects coincide in space; the coincidence of objects in space requires explanation. In this article, the author offers a critique of the modal theory of constitution. First, the definition of the constitution is examined and a new argument is offered that modal theory either does not provide asymmetry of the (...) constitution or leads to an infinite series of constitutive objects, unsatisfactorily extending ontology. Also, the author demonstrates that possible additions to the constitutive definition, which can make the definition sufficient for asymmetric relation, lead to additional theoretical difficulties, leading to the logical impossibility of constitution relation. Second, the author demonstrates that the theory of constitution offers an unsatisfactory theory of identity because it faces three problems: the overpopulation problem, the epistemic problem, and the personal problem. All of these considerations lead the author to conclude that modal constitution theory is not metaphysically satisfactory. (shrink)

The strict-tolerant approach to paradox promises to erect theories of naïve truth and tolerant vagueness on the firm bedrock of classical logic. We assess the extent to which this claim is founded. Building on some results by Girard we show that the usual proof-theoretic formulation of propositional ST in terms of the classical sequent calculus without primitive Cut is incomplete with respect to ST-valid metainferences, and exhibit a complete calculus for the same class of metainferences. We also argue that the (...) latter calculus, far from coinciding with classical logic, is a close kin of Priest’s LP. (shrink)

In the last 20 years or so, since the publication of a seminal paper by Watts and Strogatz :440–442, 1998), an interest in topological explanations has spread like a wild fire over many areas of science, e.g. ecology, evolutionary biology, medicine, and cognitive neuroscience. The topological approach is still very young by all standards, and even within special sciences it still doesn’t have a single methodological programme that is applicable across all areas of science. That is why this special issue (...) is important as a first systematic philosophical study of topological explanations and their relation to a well understood and widespread explanatory strategy, such as mechanistic one. (shrink)

In this paper, I argue that the newly developed network approach in neuroscience and biology provides a basis for formulating a unique type of realization, which I call topological realization. Some of its features and its relation to one of the dominant paradigms of realization and explanation in sciences, i.e. the mechanistic one, are already being discussed in the literature. But the detailed features of topological realization, its explanatory power and its relation to another prominent view of realization, namely the (...) semantic one, have not yet been discussed. I argue that topological realization is distinct from mechanistic and semantic ones because the realization base in this framework is not based on local realisers, regardless of the scale but on global realizers. In mechanistic approach, the realization base is always at the local level, in both ontic and epistemic accounts. The explanatory power of realization relation in mechanistic approach comes directly from the realization relation-either by showing how a model is mapped onto a mechanism, or by describing some ontic relations that are explanatory in themselves. Similarly, the semantic approach requires that concepts at different scales logically satisfy microphysical descriptions, which are at the local level. In topological framework the realization base can be found at different scales, but whatever the scale the realization base is global, within that scale, and not local. Furthermore, topological realization enables us to answer the “why” questions, which according to Polger 2010 make it explanatory. The explanatoriness of topological realization stems from understanding mathematical consequences of different topologies, not from the mere fact that a system realizes them. (shrink)

Conventionalism in sport philosophy has been rejected as unable to provide a theory of normativity and as collapsing in ethical relativism, but this criticism is rather imprecise about its target, which invites doubt about the legitimacy of the concept of conventionalism described by its critics. Instead, a more charitable and legitimate account of conventionalism is proposed, one that draws inspiration from conventionalism in axiomatic geometry and is able to avoid the counterarguments directed against conventionalism. This new model allows for a (...) number of non-conventional elements of sport, namely the definition of sport and certain central moral norms, while at the same time arguing that normativity in sport is not exhausted by them, which leaves athletic communities with authority over a broad range of norms. (shrink)

In non-causal explanations, some non-causal facts (such as mathematical, modal or metaphysical) are used to explain some physical facts. However, precisely because these explanations abstract away from causal facts, they face two challenges: 1) it is not clear why would one rather than the other non-causal explanantia be relevant for the explanandum; and 2) why would standing in a particular explanatory relation (e.g., “counterfactual dependence”, “constraint”, “entailment”, “constitution”, “grounding”, and so on), and not in some other, be explanatory. I develop (...) an explanatory relevance account which is based on erotetic constraints and show how it addresses these two challenges. (shrink)

Proponents of ontic conceptions of explanation require all explanations to be backed by causal, constitutive, or similar relations. Among their justifications is that only ontic conceptions can do justice to the ‘directionality’ of explanation, i.e., the requirement that if X explains Y , then not-Y does not explain not-X . Using topological explanations as an illustration, we argue that non-ontic conceptions of explanation have ample resources for securing the directionality of explanations. The different ways in which neuroscientists rely on multiplexes (...) involving both functional and anatomical connectivity in their topological explanations vividly illustrate why ontic considerations are frequently (if not always) irrelevant to explanatory directionality. Therefore, directionality poses no problem to non-ontic conceptions of explanation. (shrink)

Proof-theoretic semantics is an alternative to model-theoretic semantics. It aims at explaining the meaning of the logical constants in terms of the inference rules that govern their behaviour in proofs. We argue that this must be construed as the task of explaining these meanings relative to a logic, i.e., to a consequence relation. Alas, there is no agreed set of properties that a relation must have in order to qualify as a consequence relation. Moreover, the association of a consequence relation (...) to a logical calculus is not as straightforward as it may seem. We show that these facts are problematic for the proof-theoretic project but the problems can be solved. Our thesis is that the consequence relation relevant for proof-theoretic semantics is the one given by the sequent-to-sequent derivability relation in Gentzen systems. (shrink)

In this paper, we explore the conceptual problems arising when using network analysis in person- centered care (PCC) in psychiatry. Personalized network models are potentially helpful tools for PCC, but we argue that using them in psychiatric practice raises boundary problems, i.e., problems in demarcating what should and should not be included in the model, which may limit their ability to provide clinically-relevant knowledge. Models can have explanatory and representational boundaries, among others. We argue that we can make more explicit (...) what kind of questions personalized network models can address in PCC, given their representational and explanatory boundaries, using perspectival reasoning. (shrink)

This article examines Erich Przywara‘s conceptual understanding of the proofs for the existence of God. It also interprets the proofs of God’s existence. Тhe concept of God in the philosophy of Przywara is considered by exploring the nature of the relations between the transcendent sphere of God and the spiritual world of the human person. From the point of view of historiography, the role of the book “The Analogia entis” by Przywara is highlighted.

In the sport ethics literature, the general attitude with regard to the influence of commercialization in sport is to draw attention to the ways it undermines sport and morally corrupts those involved in it. This paper attempts to provide a counternarrative to this literature, focusing on criticism of commodification of sport that revolves around the idea of fairness. A brief libertarian framework is presented and three characteristics of sport are outlined, which are shown to make sport a particularly well-suited context (...) for libertarian approaches. Unlike a good deal of human activities, engaging and disengaging from sport carries few internal barriers, a fact that creates the opportunity for participants to introduce alternatives to the established way of playing sport. In this case, if alternatives to certain means of playing sport can always be found, then no concrete instance in which sport is played can truly be considered as unfair as individuals always.. (shrink)