Chemosensory systems are complex regulatory pathways capable of perceiving external signals and translating them into different cellular behaviors such as motility and development. In the δ-proteobacterium Myxococcus xanthus, chemosensing allows groups of cells to orient themselves and aggregate into specialized multicellular biofilms termed fruiting bodies. M. xanthus contains eight predicted CSS and 21 chemoreceptors. In this work, we systematically deleted genes encoding components of each CSS and chemoreceptors and determined their effects on M. xanthus social behaviors. Then, to understand how (...) the 21 chemoreceptors are distributed among the eight CSS, we examined their phylogenetic distribution, genomic organization and subcellular localization. We found that, in vivo, receptors belonging to the same phylogenetic group colocalize and interact with CSS components of the respective phylogenetic group. Finally, we identified a large chemosensory module formed by three interconnected CSS and multiple chemoreceptors and showed that complex behaviors such as cell group motility and biofilm formation require regulatory apparatus composed of multiple interconnected Che-like systems. © 2014 Moine et al. (shrink)

Nous proposons quelques remarques concernant la philosophie et son enseignement, en nous appuyant sur une conférence prononcée en 1975 par le philosophe tchèque Jan Patočka intitulée « L’homme spirituel et l’intellectuel », et dans laquelle Patočka décrit le genre de vie propre au philosophe par opposition à celui qu’il nomme « l’intellectuel » reprenant par là, et lui donnant toutefois un souffle nouveau, l’opposition platonicienne entre le philosophe et le sophiste. Nous approfondissons cette lecture par l’analyse d’un essai antérieur datant (...) de 1934, extrait du volume Liberté et sacrifice et intitulé « Remarques sur la position de la philosophie dans et en dehors du monde ». Nous souhaiterions montrer que dans ces deux textes, Patočka expose, partant de la figure de Socrate, le genre de vie du philosophe, faisant ainsi apparaître une figure de l’enseignement moins grecque que johannique. (shrink)

Cet article d'histoire éditoriale fait le point sur les neuf éditions de l'anthologie titrée Cantiques de Maisonfleur, de 1580 à 1613, son expansion et ses recompositions, et sur son éclatement dans d'autres recueils de 1591 à 1621. La coprésence de poèmes dus à des auteurs de cour connus comme catholiques et à des poèmes de spiritualité réformée ou écrits par des poètes réformés (pasteurs) fait l'objet d'un examen sous l'angle de la construction éditoriale. Selon notre hypothèse, le recueil essaie moins (...) d'unir les deux confessions qu'il ne tente de concilier le statut de sujet du roi de France, attaché à la monarchie des Valois, et de fidèle réformé. Poètes présents dans l'anthologie : Jérôme de Maisonfleur, Valagre, T. de Sautemont, Marin Le Saulx, Yves Rouspeau, A. de La Roche-Chandieu, Belleau, Du Bellay, Ronsard, Desportes, Malherbe, Bertaud, Du Perron, Pibrac, A. Favre, et autres. (shrink)

Abstract The infantilization of older adults seems morally deplorable whereas very young children are appropriate recipients of such treatment. Children, we argue, are not mentally capable of acting autonomously and reasoning clearly. However, we have difficulty reconciling this justification with the fact that many of the elders whom we respect are mentally deficient in those very same ways. In this paper, I try to make sense of this asymmetry between our justifications for infantilizing the young and our conviction that our (...) elders ought to be respected. I argue that our intuitions against adult infantilization are non-consequentialist (i.e., deontic). I consider several candidates for the deontic factor that might explain the asymmetry of our judgments and practices. I argue that a very specific kind of dignity (one that is socially constructed and reified) grounds our disparate judgments and treatments of very young and very old persons with similar needs. (shrink)

This paper provides an account of mid-level models, which calibrate highly theoretical agent-based models of scientific communities by incorporating empirical information from real-world systems. As a result, these models more closely correspond with real-world communities, and are better suited for informing policy decisions than extant how-possibly models. I provide an exemplar of a mid-level model of science funding allocation that incorporates bibliometric data from scientific publications and data generated from empirical studies of peer review into an epistemic landscape model. The (...) results of my model show that on a dynamic epistemic landscape, allocating funding by modified and pure lottery strategies performs comparably to a perfect selection funding allocation strategy. These results support the idea that introducing randomness into a funding allocation process may be a tractable policy worth exploring further through pilot studies. My exemplar shows that agent-based models need not be restricted to the abstract and the a-priori; they can also be informed by real empirical data. (shrink)

Ethics is demanding by nature, telling us what we should or should not do. But one ethical theory in particular, utilitarianism, is more demanding than most, and is often criticized as requiring too much of us. Neither utilitarianism nor deontology requires Superman to care about truth, justice, or the American way. It might not be possible for Superman to be supererogatory since very little is above or beyond the call of duty for him, given our incredibly high expectations. Virtue ethics (...) has the best chance to explain how Superman can perform supererogatory acts, since it doesn't focus on good action as such, but rather good character. While people use the name “big blue boy scout” in a derogatory way with Superman, it is a nice way to capture an ethical theory that might grant Superman’s responsibilities while allowing him a chance to live his own life: virtue ethics. (shrink)

Do extreme, unethical governmental policies often produce results opposite to those intended? This book considers the ironic outcomes of recent global events and concludes that there is a 'rule of reverse results' at work. While not a hard and fast law, the rule points out the increased probability that a policy will backfire if it is immoral while ethical policies, even if extreme, are unlikely to produce reverse results. The issue here is that of increased likelihood but not of certainty. (...) Governments can never be sure as to the effects of their actions: to some extent they are always working in the dark. But if the motivation is right, moral and humane the policies will not often produce adverse results the opposite of those intended. Based on events in global history in the Twentieth and Twenty-First centuries the chapters can each be read individually, as well as being part of the argument. (shrink)

Open Access: This paper will connect literature on epistemic injustice with literature on victims and perpetrators, to argue that in addition to considering the credibility deficit suffered by many victims, we should also consider the credibility excess accorded to many perpetrators. Epistemic injustice, as discussed by Miranda Fricker, considers ways in which someone might be wronged in their capacity as a knower. Testimonial injustice occurs when there is a credibility deficit as a result of identity-prejudicial stereotypes. However, criticisms of Fricker (...) have pointed out that credibility is part of a more complex system that includes both deficits and excesses. I will use these points to argue that we should look closer at sources of credibility excess in cases of sexual assault. This means that in addition to considering sources of victim blaming by looking at ways in which “ideal” victims are constructed, we also need to consider ways in which “ideal” perpetrators are constructed. (shrink)

We conjecture that corporate social responsibility can be indicative of managerial ethics and integrity and examine whether equity investors and financial analysts consider CSR performance when they assess firms’ disclosures of actual and forecasted earnings. We find that only adverse CSR performance affects investors’ assessments of these disclosures. In contrast, we find that both positive and adverse CSR performance affect analysts’ forecast revisions in response to firms’ disclosures. We also find that firms with adverse CSR performance exhibit lower disclosure quality (...) and earnings persistence, but do not find that firms with positive CSR performance exhibit higher levels of both measures. This asymmetric result is consistent with investors’, but not analysts’, assessments of the effect of CSR performance on corporate disclosures. Our results are robust to using a three-stage least squares approach to address endogeneity concerns and to a battery of robustness and sensitivity analyses. Overall, our findings suggest that investors and analysts consider CSR when assessing the information in earnings-related corporate disclosures. (shrink)

La fouille du puits 883, menée par la mission française de Kition à Bamboula (2017-2018), a livré de nombreux restes fauniques au sein d’un comblement daté du ive siècle apr. J.‑C. Cet article présente les résultats d’une étude collaborative réalisée par des archéozoologues qui ont mis en évidence une grande diversité animale (bétail, carnivores, coquillages, oiseaux, rongeurs, reptiles, poissons). Ce matériel faunique offre l’opportunité d’aborder le paysage animalier d’un secteur de la ville antique dans sa multiplicité, avec des animaux liés (...) directement aux pratiques économiques et domestiques (élevage, consommation carnée, utilisation d’animaux auxiliaires) dont les déchets s’avèrent de différentes natures (alimentaires, équarrissage, cadavres animaux). D’autres espèces, plus discrètes, ont su profiter des déchets et denrées produites par les habitants de ce quartier, témoignant ainsi de la porosité entre contextes urbanisés et environnements naturels. (shrink)

Erratum to: Int J Semiot Law DOI 10.1007/s11196-014-9376-7Dans la publication originale de cet article, l’auteur n’a pas cité le titre correct de la thèse de philosophie de Stefan Goltzberg.A la dernière phrase du premier paragraphe, il ne faut pas lire «il a écrit une thèse de philosophie intitulé Théorie et histoire de la philosophie du droit, philosophie du droit de Chaïm Perelman, de Theodor Viehweg, de Roscoe Pound» mais bien «il a écrit une thèse de philosophie intitulée Théorie bidimensionnelle de (...) l’argumentation. Définition, Présomption, Argument A fortiori». (shrink)

«Existe-t-il une argumentation juridique?», c’est la question à laquelle tente de répondre l’ouvrage de Stefan Goltzberg, intitulé explicitement L’argumentation juridique. Si l’auteur commence son ouvrage en posant directement la question, on en cherche aussitôt, par un réflexe de «juriste», la définition. Et il faut probablement lire l’intégralité de ce petit ouvrage pour voir se profiler une définition de l’argumentation juridique. Or, au cours de cette lecture Stefan Goltzberg nous montre en quoi chercher la définition, la poser, est déjà une marque (...) argumentative (p. 25) et certainement une marque de l’argumentation juridique. Or, Stefan Goltzberg n’est pas juriste de formation. Philosophe et linguiste, il est, notamment membre du Centre Perelman de philosophie du droit au sein duquel il a écrit une thèse de philosophie intitulé Théorie et histoire de la philosophie du droit, philosophie du droit de Chaïm Perelman, de Theodor Viehweg, de Roscoe Pound.Le droit est d’abord un objet d’ .. (shrink)

The study's purpose was to estimate the variety of foods consumed within standard and ethnic food categories by three groups of women between 18 and 35 years of age. Foreign-born Chinese women [N = 21], Chinese-American women [N = 20] and white American women [N = 23] kept 4-day food records, after instruction. Analysis of variance showed that the mean number of different foods consumed by the foreign-born Chinese was significantly [p < 0.05] lower than those eaten by the other (...) two groups for breads/cereals, dairy products, ethnic foods, fats, meats, sweets/sugars, and vegetable categories. White American women consumed significantly more dairy products and legumes/nuts than either of the groups of Chinese women. Diets of the Chinese-American women were more nutrient dense than those of the women in the other groups, containing significantly more energy, riboflavin, iron, folacin, and calcium than those of the foreign-born Chinese women. The percentage of kilocalories derived from fat [33–34%] did not differ among groups. 95% of foreign-born and 85% of Chinese-American women affirmed their ethnic identification by consuming foods belonging to Chinese cuisine; whereas, the percentage [30%] of white American women selecting Chinese food was significantly lower. Mexican and Italian foods were selected by significantly more white and Chinese-American women than by foreign-born Chinese women. Approximately 20% of both groups of Chinese women, but 49% of white American subjects, ate Japanese food. Chinese-American women retained a preference for Chinese food, similar to that of the foreign-born Chinese women. However, the Chinese-American women consumed cheeses, legumes, raw vegetables in salads, and foods from Italian and Mexican cuisines, indicating their acceptance of foods commonly consumed by white American women. Dietary acculturation among the Chinese-American women improved their diets over those of the foreign-born Chinese women and these results support the theory that consumption of a greater variety of foods increases nutrient density of diets. (shrink)

Criticism can sometimes provoke defensive reactions, particularly when it implicates identities people hold dear. For instance, feminists told they are upholding rape culture might become angry or upset, since the criticism conflicts with an identity that is important to them. These kinds of defensive reactions are a primary focus of this paper. What is it to be defensive in this way, and why do some kinds of criticism, or implied criticism, tend to provoke this kind of response? What are the (...) connections between defensiveness, identity, and active ignorance? What are the social, political, and epistemic consequences of the tendency to defensiveness? Are there ways to improve the situation? (shrink)

Faculty workload inequities have important consequences for faculty diversity and inclusion. On average, women faculty spend more time engaging in service, teaching, and mentoring, while men, on average, spend more time on research, with women of color facing particularly high workload burdens. We explore how faculty members perceive workload in their departments, identifying mechanisms that can help shape their perceptions of greater equity and fairness. White women perceive that their departments have less equitable workloads and are less committed to workload (...) equity than white men. Women of color perceive that their departments are less likely to credit their important work through departmental rewards systems than white men. Workload transparency and clarity, and consistent approaches to assigning classes, advising, and service, can reduce women’s perceptions of inequitable and unfair workloads. Our research suggests that departments can identify and put in place a number of key practices around workload that will improve gendered and racialized perceptions of workload. (shrink)

The purpose of this qualitative study was to examine the perceptions related to ethics and cheating among a representative sample of primarily female undergraduate students, compared to trends reported in the literature. Focus groups were organized to discuss nine scripted questions. Transcripts and audiotapes were analyzed and four main themes emerged: demographics of those who cheat, students’ perceptions of cheating, the role of technology in cheating, and consequences of cheating, including students’ attitudes and behaviors related to reporting cheating incidents. Bandura’s (...) Social Cognitive Theory served as the theoretical framework to understand students’ varying perceptions of and justification for cheating, as well as the dynamics of honor code violations, via group discussion. Viewpoints on cheating were regularly discussed and contradictory views were identified related to frequency and justification for cheating. Utilizing the constant comparative method, students mentioned time limitations, and pressure from peers, parents, and professors as reasons to cheat. They also discussed pressures to achieve high grades for acceptance into graduate programs. Students were also reluctant to report their classmates for cheating incidents. Repeated and comprehensive education on ethical behavior is warranted. (shrink)

In order to define modernity in the fine arts, music, and literature, this work explores the function of this category as it is used by artists, art critics, historians, and philosophers to rethink the norms of art and the links between art, politics, and life.

Feminist epistemologies consider ways in which gender influences knowledge. In this article, I want to consider a particular kind of feminist empiricism that has been called feminist radical empiricism. I am particularly interested in this view's treatment of values as empirical, and consequently up for revision on the basis of empirical evidence. Proponents of this view cite the fact that it allows us to talk about certain things such as racial and gender equality as objective facts: not just whether we (...) have achieved said equality in our society, but whether we are, in fact, all equal. I will raise the concern that the way in which they model the role of values in epistemology may be a problematic idealization of the open-mindedness of human agents. In some cases, resistance to value-change cannot be diagnosed as a failure to respond adequately to evidence. If so, the strategy of empirically testing our values that some feminist radical empiricists suggest may not be as useful a tool for social change as they think. (shrink)

An ad hominem fallacy is committed when an individual employs an irrelevant personal attack against an opponent instead of addressing that opponent’s argument. Many discussions of such fallacies discuss judgments of relevance about such personal attacks, and consider how we might distinguish those that are relevant from those that are not. This paper will argue that the literature on bias and testimony can helpfully contribute to that analysis. This will highlight ways in which biases, particularly unconscious biases, can make ad (...) hominem fallacies seem effective, even when the irrelevance is recognized. (shrink)

RésuméPartant de la considération inaugurale de.

This article, based on a socio-cognitive approach, deals with the professional training of student teachers in French agricultural education during their practical work experience. The main objective is to demonstrate that the student teacher’s social interaction with his academic advisor allows him to use and develop his professional knowledge relating to practical matters. Based on a qualitative analysis this study presents the results of an investigation of seven students and six academic advisors. The article studies the interrelations between the nature (...) of the professional knowledges in question and the processes of construction in the work. (shrink)

How do diverse groups of women in Canada define sexual harassment? To answer this question requires incorporating race and citizenship into the analysis of sexual harassment. The authors use data from seven focus groups of Canadian women. The white women with full citizenship rights most easily identify with existing legal understandings of sexual harassment and believe they have the right to report their harassment. For women of color and women without full citizenship rights, issues of racialized sexual harassment emerge as (...) central factors in their harassment experience. Black women with full citizenship rights call into question whether the term sexual harassment captures their experiences. Filipinas working as live-in caregivers on limited visas demonstrate how racism and lack of citizenship changes definitions of sexual harassment. Their experiences of harassment combine elements of isolation due to their lack of citizenship, racialized sexual harassment, and abuse. The authors argue that intersectional analyses are needed to understand women’s harassment experiences and their ability to complain and seek legal recourse. (shrink)

There are many good reasons to learn about the lives of people who have less social privilege than we do. We might want to understand their circumstances in order to have informed opinions on social policy, or to make our institutions more inclusive. We might also want to cultivate empathy for its own sake. Much of this knowledge is gained through social scientific or humanistic research into others' lives. The entitlement to theorize about or study the lives of marginalized others (...) is often granted under the presumption of academic freedom. This paper will not question whether academic freedom licenses us to do so in the first place ; instead, I will... (shrink)

Many criticisms of epistemic logic have centered around its use of devices such as idealized knowers with logical omniscience and perfect self-knowledge. One possible response to such criticisms is to say that these idealizations are normative devices, and that epistemic logic tells us how agents ought to behave. This paper will take a different approach, treating epistemic logic as descriptive, and drawing the analogy between its formal models and idealized scientific models on that basis. Treating it as descriptive matches the (...) way in which some philosophers, including one of its founders, Jaako Hintikka, have thought about epistemic logic early in its history. Further, the analogy between the two fields will give us a way to defuse criticisms that see epistemic logic as unrealistic. For example, criticizing models of epistemic logic in which agents know all propositional tautologies as being unrealistic would be like criticizing frictionless planes in physics for being unrealistic. Each one would certainly be an unsuitable model for studying some kinds of phenomena, but is entirely appropriate for others. After outlining the analogy between epistemic and scientific models, we will discuss some ways in which idealizations are used by different research programs in epistemic logic. (shrink)

This book redresses the balance by examining theory, research, policy, and practice in both fields.

In this article, we present a Critical Discourse Analysis (CDA) of the online discussion board posts of a group of elementary educators as they discussed their interpretations of four historical timelines that presented different – sometimes complementary and sometimes contradictory – information about the goals of the Lewis & Clark expedition and its effects on Native populations. This activity was one part of a virtual professional development course on anti-racist critical literacy pedagogy for K-8 teachers, which was structured around three (...) key concepts: 1) considering multiple perspectives can disrupt common understandings of texts; 2) issues of power determine what is present and absent in the stories authors tell; and 3) texts are social constructions that can be deconstructed and reconstructed. The teachers featured in this article worked in the same urban district and throughout their discussion, we found that they perpetuated discourses of Whiteness while simultaneously attempting to disrupt them. However, we also found discursive reconstructive potential in the ways one teacher responded to her assumptions being interrupted by a course facilitator, as well as the value of using CDA to examine teacher language. Our findings point to further directions for teacher educators working to foster racial and critical literacy. (shrink)