Simone de Beauvoir held that human experience is intrinsically ambiguous and that there are no values extrinsic to experience, but she also designated some actions as absolute evil. This essay explains how Beauvoir utilized an intrinsic absolute value to ground an action-guiding principle of freedom that justifies her notion of evil. Morgan's analysis counters Robin May Schott's objections that Beauvoir failed to systematically justify her notion of absolute evil and that Beauvoir shifted from a “logic of action” to a “logic (...) of history” when she utilized the concept. (shrink)

Simone de Beauvoir held that human experience is intrinsically ambiguous and that there are no values extrinsic to experience, but she also designated some actions as absolute evil. This essay explains how Beauvoir utilized an intrinsic absolute value to ground an action-guiding principle of freedom that justifies her notion of evil. Morgan’s analysis counters Robin May Schott’s objections that Beauvoir failed to systematically justify her notion of absolute evil and that Beauvoir shifted from a “logic of action” to a “logic (...) of history” when she utilized the concept. (shrink)

Recently, we reported that melanoma risk in redheads is linked not only to pale skin, but also to the synthesis of the pigment – called pheomelanin – that gives red hair its color. We demonstrated that pheomelanin synthesis is associated with increased oxidative stress in the skin, yet we have not uncovered the chemical pathway between the molecule pheomelanin and the DNA damage that drives melanoma formation. Here, we hypothesize two possible pathways. On one hand, pheomelanin might generate reactive oxygen (...) species (ROS) that directly or indirectly cause oxidative DNA damage. On the other hand, pheomelanin synthesis might consume cellular antioxidant stores and make the cell nucleus more vulnerable to other endogenous ROS. Uncovering the mechanistic pathway between pheomelanin and oxidative DNA damage will be an important step in developing strategies to lower melanoma risk in redheads. (shrink)

Simone de Beauvoir incorporates a significantly altered form of the Hegelian master/slave dialectic into "The Ethics of Ambiguity." Her ethical theory explains and denounces extreme wrongdoing, such as the mass murder of millions of Jews at the hands of the Nazis. This essay demonstrates that, in the Beauvoirean dialectic, the Nazi value system (and Hitler) was the master, Adolf Eichmann was a slave, and Jews were denied human status. The analysis counters Robin May Schott's claims that "Beauvoir portrays the attitudes (...) of the oppressor as defined fundamentally in relation to the oppressed" and that her use of the dialectic is "inadequate to account for how human beings create extreme situations of evil, such as that of genocide.". (shrink)