As technology's frontiers advance, we acquire the capacity to alleviate the aspects of suffering and sorrow that are caused by our genetic programming, while also inviting unwelcome side consequences. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), a bacterial defense system with genome editing capabilities, is now being implemented to startling results. It is being used to correct for harmful mutations by permanently altering genes, promising to eliminate defects in whole species. Advantages notwithstanding, and apart from insufficiently considered dangers precipitated by (...) the well‐intended technology, there are other moral issues to consider. What does existence look like in which humans become resistant to experiencing genetic defects? We can welcome medical innovation's reduction of undue hardship, but is there a threshold past which a permanently improved version of us makes us ineligible to participate in the human condition? This essay offers a theological and Aristotelian critique of using CRISPR for extensive human gene editing, arguing that it is our imperfections, including susceptibility to disease, decline due to aging, and the ephemerality of joy, which make us human. (shrink)

In The Altruistic Species, Andrew Michael Flescher and Daniel L. Worthen explore these questions through the lenses of four disciplinary perspectives—biology, psychology, philosophy, and religion.

The idea of moral evil has always held a special place in philosophy and theology because the existence of evil has implications for the dignity of the human and the limits of human action. Andrew M. Flescher proposes four interpretations of evil, drawing on philosophical and theological sources and using them to trace through history the moral traditions that are associated with them. The first model, evil as the presence of badness, offers a traditional dualistic model represented by Manicheanism. The (...) second, evil leading to goodness through suffering, presents a theological interpretation known as theodicy. Absence of badness—that is, evil as a social construction—is the third model. The fourth, evil as the absence of goodness, describes when evil exists in lieu of the good—the "privation" thesis staked out nearly two millennia ago by Christian theologian St. Augustine. Flescher extends this fourth model—evil as privation—into a fifth, which incorporates a virtue ethic. Drawing original connections between Augustine and Aristotle, Flescher’s fifth model emphasizes the formation of altruistic habits that can lead us to better moral choices throughout our lives. Flescher eschews the temptation to think of human agents who commit evil as outside the norm of human experience. Instead, through the honing of moral skills and the practice of attending to the needs of others to a greater degree than we currently do, Flescher offers a plausible and hopeful approach to the reality of moral evil. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Repentance: The Meaning and Practice of TeshuvahAndrew FlescherRepentance: The Meaning and Practice of Teshuvah Louis E. Newman Woodstock, VT: Jewish Lights Publishing, 2010. 224 pp. $24.99Louis Newman’s Repentance is a welcome and comprehensive treatment of the Jewish tradition’s dealing with the tricky question of how individuals who form wicked characters address sin and restore their membership in the moral community, an activity that Aristotle, who believed that the (...) virtuous and non-virtuous have little to say to one another, thought to be scarcely possible. Newman’s perspective is decisively Aristotelian but not as pessimistic as Aristotle’s. Primarily using biblical and Talmudic sources, but also with an eye toward the insights of other traditions as well as contemporary religious thought, Newman argues that the process of atonement among those who have developed the worst sorts of habits is one of a tradition’s providing for the prospectively repentant individual with a self-awareness sufficient to attend to compensate for that individual’s penchant for self-deception. Yom Kippur, the holiday in the Jewish tradition dedicated to atonement, is an opportunity that bears down equally on every Jew to cleanse oneself of the sinfulness in which one has inevitably taken part in the previous year (58–61). Newman elaborates various respects in which Judaism anticipates that one will have been seduced by yetzer ha-ra (“evil force”) and warns of the ignorance of believing that one is immune to evil’s pervasive influence. Teshuvah, in keeping with this conviction, is characterized as the opportunity to re-catch the spark of goodness and purity with which one was initially endowed (29).Newman elucidates at least two forms of self-knowledge in which atonement consists. First there is a communal self-knowledge that both sin and atonement are basic to human existence. We are hardwired to become “unclean” and therefore require a means of becoming alerted to the importance of purging ourselves in the setting of a congregation. Newman builds upon Paul Ricoeur’s insight from The Symbolism of Evil that a fear of contaminating created goodness always stands in the background of our psyches (29). Once we have become aware of such a threat, we will be prepared to address it. The second sort of self-knowledge pertains to an awareness of the specific [End Page 221] senses in which we have wronged others (and ourselves), dispositions and deeds of which we can be made cognizant only because of the prior humility encouraged by the tradition that asserts that all of us are in need of atonement. The idea of Teshuvah makes possible our ability to say to ourselves the “It is I” that is necessary to assume responsibility for atonement (83). It is importantly ironic, argues Newman, that Teshuvah is the opposite of the avoidance of wrongdoing, for to know oneself as one who has shunned the good one must categorically embrace one’s culpability and only then address one’s specific transgressions (86). Remorse, in this sense, goes hand in hand with moral responsibility. Newman’s observation is refreshingly Augustinian and Aristotelian.In contrast to other volumes on Jewish repentance, this one narrowly attends to the problem of reversing the irreversible (76). Newman argues that remorse, the idea that we are never fully worthy unto ourselves, furnishes us with the ability to know ourselves as beings in need of forgiveness (and in need of forgiving ourselves). Since sin is a natural condition, addressing sin by building into our psychological expectations that we are sinners must also become part of the moral life cycle. This is something that a religious tradition, like Judaism, can help us to do from the beginning of our moral consciousness in our adult lives. According to Newman, we should relinquish all efforts to see ourselves as free of wrongdoing lest we become “slaves to an image of perfection that is unattainable” (84). We are all, in varying degrees, in the process of forming wicked characters; yet, paradoxically, it is precisely seeing ourselves in this way that prevents against a resistant characterological plaque transforming into an irremovable tartar.Newman does address the separately interesting cases of irredeemable sinners and... (shrink)

The transplant community has faced unprecedented challenges balancing risks of performing living donor transplants during the COVID-19 pandemic with harms of temporarily suspending these procedures. Decisions regarding postponement of living donation stem from its designation as an elective procedure, this despite that the Centers for Medicare and Medicaid Services categorise transplant procedures as tier 3b (high medical urgency—do not postpone). In times of severe resource constraints, health systems may be operating under crisis or contingency standards of care. In this manuscript, (...) the United Network for Organ Sharing Ethics Workgroup explores prioritisation of living donation where health systems operate under contingency standards of care and provide a framework with recommendations to the transplant community on how to approach living donation in these circumstances.To guide the transplant community in future decisions, this analysis suggests that: (1) living donor transplants represent an important option for individuals with end-stage liver and kidney disease and should not be suspended uniformly under contingency standards, (2) exposure risk to SARS-CoV-2 should be balanced with other risks, such as exposure risks at dialysis centres. Because many of these risks are not quantifiable, donors and recipients should be included in discussions on what constitutes acceptable risk, (3) transplant hospitals should strive to maintain a critical transplant workforce and avoid diverting expertise, which could negatively impact patient preparedness for transplant, (4) transplant hospitals should consider implementing protocols to ensure early detection of SARS-CoV-2 infections and discuss these measures with donors and recipients in a process of shared decision-making. (shrink)