Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

This study presents a theory of causally complex configurations of antecedent conditions influencing the adoption versus non-adoption of international supplier ethical certification-standards. Using objective measures of antecedents and outcomes, a large-scale study of exporting firms in the cut-flower industry in two South American countries supports the theory. The theory includes the following and additional propositions. No single -antecedent condition is sufficient for accurately predicting a high membership score in outcome conditions; the outcome conditions include a firm’s adoption or rejection of (...) a product certification. No single -antecedent condition is necessary for accurately predicting high scores in the outcome condition. A few complex antecedent conditions are sufficient but the occurrence of each is not necessary for accurately predicting high scores in an outcome condition. Causal asymmetry of antecedent conditions indicating adoption versus non-adoption of specific ethical standards occurs—that is, causal conditions leading to rejection are not the mirror opposites of causal conditions leading to adoption. (shrink)

The systemic complexity of sustainable development imposes a major cognitive challenge to students’ learning. Faculty can explore new approaches in the classroom to teach the topic successfully, including the use of technology. We conducted an experiment to compare the effectiveness of a simulation vis-à-vis a case-based method to teach sustainable development. We found that both pedagogical methods are effective for teaching this concept, although our results support the idea that simulations are slightly more effective than case studies, particularly to teach (...) its multidimensional and inter-temporal nature. Therefore, our findings suggest the use of both simulations and case studies as pedagogical tools to convey the main ideas associated with sustainable development. (shrink)

This article engages with socialist republicanism, which is preoccupied with extending freedom as non-domination, central to the neo-republican revival, from the political sphere of formal democracy to the economic sphere of capitalist production. Firstly, we discuss the transition from neo-republicanism to socialist republicanism. Secondly, we reconstruct the socialist republicanism of Antonio Gramsci, who was involved in the council movements in Turin in 1919–20. We argue that Gramsci applies the republican vocabulary of servitude to describe the capitalist workplace and analyse the (...) workers’ councils as republican forms, allowing for popular self-determination in the economic sphere. Consequently, we contribute to the ongoing exploration of the historical, political, and conceptual affinities between republicanism and socialism and inscribe Gramsci as a key thinker in this endeavour. (shrink)

Adaptation to right-shifting prisms improves left neglect for mental number line bisection. This study examined whether adaptation affects the mental number line in normal participants. Thirty-six participants completed a mental number line task before and after adaptation to either: left-shifting prisms, right-shifting prisms or control spectacles that did not shift the visual scene. Participants viewed number triplets (e.g. 16, 36, 55) and determined whether the numerical distance was greater on the left or right side of the inner number. Participants demonstrated (...) a leftward bias (i.e. overestimated the length occupied by numbers located on the left side of the number line) that was consistent with the effect of pseudoneglect. The leftward bias was corrected by a short period of visuomotor adaptation to left-shifting prisms, but remained unaffected by adaptation to right-shifting prisms and control spectacles. The findings demonstrate that a simple visuomotor task alters the representation of space on the mental number line in normal participants. (shrink)

In their paper, “Helpful Lessons and Cautionary Tales: How Should COVID-19 Drug Development and Access Inform Approaches to Non-Pandemic Diseases?” Holly Fernandez Lynch and colleagues have present...

Prior research suggests that voluntary environmental governance mechanisms operate to enhance a firm’s environmental legitimacy as opposed to being a driver of proactive environmental performance activities. To understand how these mechanisms contribute to the firm’s environmental legitimacy, we investigate whether environmental corporate governance characteristics are associated with voluntary environmental disclosure. We examine an increasingly important attribute of a firm’s disclosure setting, namely the disclosure of greenhouse gas (GHG) information. GHG information represents proprietary non-financial information about the firm’s exposure to environmental (...) concerns and is related to the firm’s operations and future profitability. Thus, we expect governance participants would view such information as a potentially important strategic device for managing stakeholders’ demands for information concerning environmental risks. We find that the presence of an environmental committee and a Chief Sustainability Officer (CSO) is positively associated with the likelihood of GHG disclosure and that CSOs are associated with disclosure transparency. Further analysis reveals that the likelihood of disclosure is associated with committee size, number of committee meetings, expertise of committee members and CSO, and overlap between the environmental committee and audit committee. Only expertise of the environmental committee members and the CSO are associated with GHG disclosure transparency, while larger committees tend to be associated with lower transparency. Our results are particularly important to those with interests in evaluating the potential role that corporate governance mechanisms play in responding to stakeholder concerns about environmental risks. Directors and officers who are considering appointment to similar governance positions, may wish to consider what attributes would make such governance positions more influential. (shrink)

Although abortion remains one of the most controversial issues of our age, to date most studies have centered on the debate in Western countries. This book discusses abortion in a non-Western, non-Christian context - in Thailand, where, although abortion is illegal, over 200,000 to 300,000 abortions are performed each year by a variety of methods. The book, based on extensive original research in the field, examines a wide range of issues, including stories of the real-life dilemmas facing women, popular representations (...) of abortion in the media, the history of the debate in Thailand and its links to politics. Overall, the work both highlights the voices of women and their subjective experiences and perceptions of abortion, and in addition places these 'women's stories' in an analysis of broader socio-political gender and the power relations - national and international - that structure sexuality and women's reproductive health decisions. (shrink)

Relying heavily on Thomas Dunfee's work, this article conducts an in-depth analysis of the relationship between law and business ethics in the context of corporate information security. It debunks the two dominant arguments against corporate investment in information security and explains why socially responsible corporate conduct necessitates strong information security practices. This article argues that companies have ethical obligations to improve information security arising out of a duty to avoid knowingly causing harm to others and, potentially, a duty to exercise (...) unique capabilities for the greater social good and to buttress stable functioning of social institutions. (shrink)

According to the Institute of Medicine, chronic pain affects at least 116 million adults in the United States, which is more than the total affected by heart disease, cancer, and diabetes combined. Pain costs the nation up to $635 billion each year in medical treatment and lost productivity. It has been conceptualized as a public health problem due to its prevalence, seriousness, disparities, vulnerable populations, the utility of population health strategies, and the importance of prevention at both the population and (...) individual levels. For many patients, treatment of pain is inadequate due to uncertain diagnoses, societal stigma, the lack of effective treatments, and inadequate patient and clinician knowledge about the best ways to manage pain. This article explores the inadequate treatment of pain in the U.S. and the subsequent rise of prescription painkiller abuse, misuse, and overdoses. This is followed by a review of the actions taken by states to regulate the prescribing of controlled substances. (shrink)

Where was God? Where was the intelligent designer of the universe when 1.5 million children were turned into smoke by zealous Nazis? Where was the all powerful, all knowing, wholly good being whose very essence is radically opposed to evil, while millions of children were starved to death by Stalin, had their limbs chopped off with machetes in Rwanda, were turned into amputees by the diamond trade in Sierra Leone, and worked to death, even now, by the child slave trade (...) that, by conservative estimates, enslaves 250 million children worldwide?Without divine justice, all of this suffering is gratuitous. How, then, can a wholly good, all-powerful God be believed to exist? The existence of evil is the most fundamental threat to the traditional Western concept of an all-good, all-powerful God. Both natural evil, the suffering that occurs as a result of physical phenomena, and moral evil, the suffering resulting from human action, comprise the problem of evil. If evil cannot be accounted for, then belief in the traditional Western concept of God is absurd. (shrink)

I am deeply worried about your guest editorial,1 please allow me a few bullet points: Trying to dispel some of the counterarguments to sex selection, your argument of prospective parents’ autonomy is void. If anyone has a right to determine his or her sex, it would be the person concerned, in this case the unborn child. ….

The creation of a specialized executive position that oversees sustainability activities represents a distinct shift in the structure of top management teams and their approach for addressing sustainability concerns. However, little is known about these management team members, namely the corporate sustainability officers or CSOs. We examine CSO appointments and their association with subsequent sustainability performance. Our results indicate that the creation of a CSO position may represent more of a symbolic versus substantive governance mechanism. Further tests suggest that CSO (...) expertise and the firm’s existing sustainability performance affect the association between the CSO and post-appointment sustainability performance. We find no association between CSO appointments and subsequent sustainability performance for firms that were already poor performers, while firms possessing relatively higher levels of prior sustainability performance appointing a CSO begin to experience significant improvements to performance after 3 years. We further find that CSOs with prior sustainability expertise are associated with increases in sustainability performance in firms that were already strong performers, but not in firms with poor sustainability performance. Non-expert CSOs, on the other hand, are associated with initial decreases in performance for poor performing firms, whereas better performing firms hiring non-expert CSOs are able to rely on other sustainability attributes of the firm and benefit from improvements in performance in the long term. We discuss the potential importance of these positions as it relates to symbolic versus substantive governance mechanisms through the lens of top management team literature streams. (shrink)

This dissertation alleges to successfully defend the argument from evil and thereby show that belief in an omnipotent, omniscient and omnibenevolent god is implausible. The three basic premises of the argument juxtapose the perfect attributes of the traditional Western notion of god to the existence of evil in an attempt to lead to the conclusion that god lacks one or more of the aforementioned attributes. Though some argue that the conclusion is not necessitated by the premises since there is no (...) logical inconsistency in asserting both that god possesses these attributes and that evil exists, it is argued here that a suppressed premise needs to be made explicit for the argument to function properly such that evil can be taken as evidence against the existence of a perfect deity. ;The theist proposes a variety of solutions to the apparent discord engendered by the coexistence of evil and a perfect deity. J. L. Mackie, in criticizing these various theistic proposals, claims that they all are either adequate or fallacious. Adequate solutions are comprised, essentially, of a denial of one of the three original premises of the argument, i.e., that either omnipotence, omniscience, omnibenevolence or evil is not real. The fallacious solutions, of which there are four types generally thought to be exhaustive, are shown to be inadequate for salvaging the traditional Western concept of deity. Familiar themes discussed among the fallacious solutions are: that the world is better with some evil than without; evil is necessary as a contrast to good; evil is necessary to bring about a greater good; evil is necessary for soul-making; evil is the result of free-will. ;Finally, a solution proposed by Clement Dore which does not properly fit into Mackie's schema, the "pollution" solution, so nicknamed because evil is viewed as a waste by-product of the natural functioning of causal laws upon the matter of the universe, is discussed. Four possible interpretations of this solution are offered and each interpretation, in turn, is found to be invalid. In conclusion, evil is shown to be powerful evidence against the existence of an omnipotent, omniscient and omnibenevolent god. (shrink)

There is yet one more proposed solution to the argument from evil which merits attention. Though it does have elements in common with other proposed solutions in that it postulates a justifying end to account for the existence of all evil, it is different in that evil is viewed as nothing more than a polluting by-product of the proper functioning of the laws of nature in their industrious manufacture of the summum bonum. The unimpeded functioning of the laws of nature (...) is seen as necessary for the production and creation of a justifying (indiscernible) end and evil or suffering is merely a foreseen but unfortunate by-product of this natural machinery. The place and function of evil in this solution is what is novel: it is not a greatness-making property, nor is it a punishment or warning from on high, nor is its usefulness an aesthetic or contrasting one, nor is it the result of free will. Evil is admitted as just plain evil; it itself plays no role to serve the valuable end, which is precipitated by the unimpeded operation of natural laws upon the universe. Evil here is seen to play the same role that pollution might: it is a foreseen and unfortunate consequence of the means used to produce the coveted final product. -/- Professor Clement Dore, in his book entitled Theism,[1] introduces this solution in which evil itself plays no role to serve an enormously valuable end, yet is necessitated by this end. However, in order for the theist to be in a position to defend Dore's claim, a viable interpretation of the justifying, indiscernible end, must be proposed. To assess the validity of Dore's schema, four apparently exhaustive interpretations of the justifying end will be presented. It will be argued here that each of these possible interpretations is, in one respect or another, inadequate. The result is that the concept of the justifying, indiscernible end and its relation to Dore's overall schema lacks lucidity. In addition, other problems with this solution will be discussed in order to show that severe flaws exist in the solution as a whole. (shrink)

La percepción sensorial nos habla de la percepción del mundo. Es por eso que, descifrar el modo en que los médicos percibían a la enfermedad y al enfermo en un determinado marco histórico, nos permitirá reconstruir y re-componer los valores culturales de ese momento. Buscaremos delinear a través del material heurístico seleccionado este redescubrimiento del cuerpo, en donde el abordaje sensorial será un puente para comprender la complejidad de la enfermedad. La primera aproximación del médico se hará a través del (...) tacto. En este sentido, por la contigüidad y la proximidad, la mano y el tacto han estado, desde tiempos remotos, ligados a la curación y al alivio del dolor. (shrink)

The author evaluates susan haack's criticisms of michael dummett's logical intuitionism and concludes that haack fails to discredit dummett's position. Haack argues that dummett's version fails since (1) he rejects inductive evidence; (2) cannot distinguish ultimately between truth- and assertibility-Conditions; and (3) recognizes that his arguments, Regrettably, Establish antirealism (i.E., Subjective idealism) for all areas. The author shows that dummett accepts inductive evidence for the set of decidable cases, Distinguishes between truth- and assertibility-Conditions by accepting that a sentence may be (...) assertible but not true, And that haack's conclusion regarding (3) rests on her misreading. ((please note that an important quote was omitted on p. 338 and the errata appears in a later issue of "philosophical studies".(). (shrink)

Review of extant research on the corporate environmental performance (CEP) and corporate financial performance (CFP) link generally demonstrates a positive relationship. However, some arguments and empirical results have demonstrated otherwise. As a result, researchers have called for a contingency approach to this research stream, which moves beyond the basic question “does it pay to be green?” and instead asks “when does it pay to be green?” In answering this call, we provide a meta-analytic review of CEP–CFP literature in which we (...) identify potential moderators to the CEP–CFP relationship including environmental performance type (e.g., reactive vs. proactive performance), firm characteristics (e.g., large vs. small firms), and methodological issues (e.g., self-report measures). By analyzing these contingencies, this study attempts to provide a basis on which to draw conclusions regarding some inconsistencies and debates in the CEP–CFP research. Some of the results of the moderator analysis suggest that small firms benefit from environmental performance as much or more than large firms, US firms seem to benefit more than international counterparts, and environmental performance seems to have the strongest influence on market-measures of financial performance. (shrink)