Developing World Bioethics, Volume 22, Issue 3, Page 126-139, September 2022.

(i) God is omniscient; therefore, for any change, C, among particulars, God knows the occurrence of C. (ii) If God knows the occurrence of C, then X. (iii) not-X. It is clear that the set of propositions (i)—(iii) is inconsistent. This is the general form of two problems—which I call the ‘problem of change in knowledge’ (PCK) and the ‘problem of change in essence’ (PCE)—for Avicenna concerning God’s knowledge of particulars. No work in the secondary literature has discussed exactly what (...) PCK and PCE are. In this paper, I will clarify exactly what they are. (shrink)

God is omniscient; therefore, He knows that ‘the flower in my hand is red.’ If God knows that ‘the flower in my hand is red,’ then He knows it perceptually. God does not know anything perceptually. It is clear that the set of propositions – form an inconsistent triad. This is one of four problems with which Avicenna was engaged concerning God's knowledge of particulars, which I call the problem of perceptual knowledge. In order to solve PPK and three other (...) problems, Avicenna has developed a theory concerning God’s knowledge of particulars. Secondary literature around Avicenna’s theory of God’s knowledge of particulars has mostly directed its attention to give an account of Avicenna’s positive theory rather than the problems which that theory was designed to solve. But this paper will not do the same thing as this secondary literature. In contrast, in this paper, I will concentrate on the characterization of one of the problems, i.e., PPK, because of which Avicenna has presented his positive theory of God’s knowledge of particulars. In short, this paper aims to show why Avicenna deems explaining God’s knowledge of, say, the redness of a flower, via his accepted theory of perception as problematic. In this regard, I will extract three versions of PPK based on Avicenna's philosophy and through it will shed some light on Avicenna’s theory of God’s knowledge of particulars. (shrink)

I show that the assumption of highly structured propositions can be leveraged to provide a unified semantics for various propositional logics of impure ground in a very expressive and flexible way. It is shown, in particular, that the induced models are capable of capturing an infinitude of grounding facts that follow from unrestricted logics of ground, but, due to certain artificial restrictions, are left unaccounted for by the existing semantics in the literature. It is also shown that our models, unlike (...) the ones in the literature, are easily extendable to capture certain distinct views about iterated as well as identity grounding. (shrink)

It seems Avicenna’s passages regarding God’s knowledge of particulars are susceptible of being given two different types of interpretation. The main difference between these two accounts of his theory concerning God’s knowledge of particulars is that one of them, which I call the Neglected Interpretation, appeals to some metaphysical entities as the proxies of concrete particular objects, which are distinct from God’s essence, to explain God’s knowledge of particulars, while the other type does not. The views of post-Avicennian thinkers like (...) Suhrawardī and Ṭūsī of Avicenna’s account are classifiable under the Neglected Interpretation, as shown by their objections to Avicenna’s theory of God’s knowledge of particulars. This type of interpretation of Avicenna’s theory of God’s knowledge of particulars has been neglected in the secondary English literature on the issue. In this paper, I will present a reconstructed version of this type of interpretation of the Avicennian theory of divine knowledge. (shrink)

It seems Avicenna’s passages regarding God’s knowledge of particulars are susceptible of being given two different types of interpretation. The main difference between these two accounts of his the...

God is omniscient; therefore, for any two propositions, P1 and P2, God knows both that P1 and P2. If God knows multiple things, then God is not simple. But, God is supposed to be a s...

In lieu of an abstract, here is a brief excerpt of the content:A Long Way to God's Mutability:A Response to Ebrahim AzadeganAmirhossein Zadyousefi (bio)I. IntroductionIn his "On the Incompatibility of God's Knowledge of Particulars and the Doctrine of Divine Immutability: Towards a Reform in Islamic Theology" (2020, 2022) Ebrahim Azadegan tries to make room for what he calls a reform in Islamic theology. Affirming that God's knowledge of particulars is inconsistent with God's immutability, Azadegan puts forward a theory of God's (...) knowledge of particulars, inspired from Sadrā's philosophy, which allows one to (1) explain God's knowledge of particulars and (2) hold that God is mutable. That is, Azadegan, accusing Avicenna of having the dogma of God's immutability, abandons God's immutability in favor of God's knowledge of particulars and thinks that a God who knows particulars but is mutable is more perfect than a God who does not know particulars but is immutable. In the present response, I shall show that Azadegan's project is not as easy as he thinks, and I will criticize it. Let us have a short look at Azadegan's project. II. Azadegan's ProjectAzadegan's 2020 essay consists of three parts. In the following, I will present a brief summary of each. In the first part, Azadegan tries to delineate the main contours of a debate in Islamic intellectual tradition over God's knowledge of particulars—a debate chiefly between Ghazālī and Avicenna—and shows how God's knowledge of particulars is in tension with God's immutability. He summarizes this debate in the following argument:1. God is omniscient. 2. Every omniscient being knows all past, present, and future particular states of the world and of individuals. 3. Particular states of the world and of individuals change.4. Every sort of knowledge will change with the change of its object. 5. [Therefore] God's knowledge of occurrent particulars changes. [End Page 166]6. Knowledge is an intrinsic property of every individual, including God.7. [Therefore] God's intrinsic property regarding His knowledge of particulars changes.8. God's intrinsic properties are His essential properties.9. [Therefore] God's essential properties change. 10. [Therefore] God is not immutable.1Then he states that God's knowledge of particulars, in both Avicenna's and Ghazālī's views, is inconsistent with God's immutability.2 That is, if one holds that God knows particulars (premise 2), according to the argument above, one has to accept that God is not immutable (premise 10). According to Azadegan, Avicenna denies God's knowledge of particulars, that is, premise 2 of the argument above, in order to avoid its conclusion (premise 10). 3 But, Azadegan is well aware that only temporal knowledge of changing particulars entails a change in God's essence. So, he mentions that by introducing knowledge in a universal way Avicenna tries to save premise 2 of the preceding argument while denying its fifth premise. 4But Azadegan thinks that Avicenna's appeal to knowing in a universal way does not help him, and this way of knowing particulars "cannot in the end accommodate God's knowledge of occurrent particulars and the phenomenal states of other minds"5 and "the contents of our senses and particular mental states."6 "God does not" even "know what time it is"7 and "what particular qualitative or phenomenal properties any particular individual has been experiencing when he or she has felt a pain or some other sensation."8 Azadegan states that Avicenna warmly welcomes such a result because Avicenna thinks that God's lack of knowledge of changing particulars partly constitutes God's perfectness.9 But he disagrees with Avicenna and, following Ghazālī, holds that such a God is perfect only in name. Following Ghazālī, Azadegan makes a connection between God's perfectness, God's immutability, and God's knowledge of particulars and holds that a God who knows particulars but is mutable is more perfect than a God who does not know particulars but is immutable.10 He believes that the conception of God introduced by Avicenna (a God who lacks knowledge of changing particulars) does not correspond to the God introduced by... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Hylomorphism, Change, and God's Mutability:A Rejoinder to Ebrahim AzadeganAmirhossein Zadyousefi (bio)In "A Long Way to God's Mutability: A Response to Ebrahim Azadegan"1 I tried to challenge what Azadegan says in his "On the Incompatibility of God's Knowledge of Particulars and the Doctrine of Divine Immutability: Towards a Reform in Islamic Theology."2 Then, in his "Necessary Existence, Immutability, and God's Knowledge of Particulars: A Reply to Amirhossein Zadyousefi,"3 Azadegan (...) replies to my response. In my response to Azadegan, I discussed many points, and Azadegan did not deal with all of them in his reply. So, in this short rejoinder, I will deal with what Azadegan has said about some of my criticisms. Before proceeding, I should say that in my response to Azadegan I remained neutral on whether God is mutable or not. All I have done there is to show that Azadegan's path to God's mutability by adopting Sadra's knowledge-by-presence theory is not as easy as it initially seems. Also, I have tried to show that Avicenna does not adopt the dogma of God's immutability. Rather, he has some reasons for adopting this view. I understand that one might challenge Avicenna's reasons for God's immutability. But, as I insisted in my first response to Azadegan, we should be careful not to conflate having a dogma with having a bad reason.In his reply to my response, Azadegan states that "according to Zadyousefi, Avicenna believes in an incompatibility between God's necessary existence and the denial of divine immutability." Then, he presents the following argument that he calls "Argument from God's Necessary Existence to His Immutability": [End Page 196]A1:1. God is a necessary existent.2. A necessary being possesses his attributes necessarily (the principle of 'Necessity of a necessary Being's Attributes').3. If God has a certain knowledge-set, then He has it necessarily.4. A necessary existent exists in all possible worlds and at all times.5. In all possible worlds God has a certain fixed knowledge-set.6. So what God knows at w1 (in a possible world w1 or in time t1 in the actual world) is the same as what God knows at w2 (or t2).7. Therefore, God is immutable."4But I have not argued by virtue of the above argument that according to Avicenna God's being a necessary existent is inconsistent with God's mutability. Instead, I have presented the following argument to show that:A2:Avicenna, following Aristotle, explains change via matter. That is, if something undergoes change or can undergo change, then it is composed of matter and form and hence it is material. Now, since every material being is constituted by a matter-form compound, every material being is dependent on its constituents (matter and form) and therefore is a contingent being. For a contingent being, according to Avicenna, is a being that is dependent on something else. So, every material being would be contingent. Therefore, God's mutability entails God's being material, which in turn entails God's being contingent. So, God's being a necessary existent is incompatible with God's mutability.As we can see, this argument is completely different from A1. I suspect Azadegan's A1 is a misinterpretation of an objection that I raised against him. In his initial paper, following Ghazālī, Azadegan states that, according to Avicenna, God's knowledge of particulars is in tension with God's eternality. In my response, I argued that this is not the case. According to Avicenna, God's knowledge of changing particulars, based on some certain mechanism for knowing the occurrence of a change among particulars (i.e., knowledge of change through indexical propositions), is in tension with God's being a necessary existent. I stated this inconsistency as follows:A3:8. God is omniscient.9. Therefore, for any change C among particulars, God knows the occurrence of C.10. For any knower S, if S knows the occurrence of C, then S's set of knowledge changes (based on indexical propositions). [End Page 197]11. If S's set of knowledge changes... (shrink)

Allegedly, according to Avicenna’s theory of God’s knowledge of particulars, God knows particulars in a universal way or universally. But, it is controversial how we should interpret knowing in a universal way. It seems knowing in a universal way is a black-box in Avicenna’s theological context. However, Peter Adamson in his valuable ‘On Knowledge of Particulars’ has suggested a novel approach to decode this black-box in Avicenna’s theological context. According to Adamson, the key for this black-box is embedded in Avicenna’s (...) epistemological context, i.e., Kitāb al-Burhān. It seems Adamson’s interpretation of Avicenna’s theory of God’s knowledge of particulars consists of two main steps. Firstly, on the basis of Kitāb al-Burhān, he tries to show that knowing in a universal way amounts to knowing syllogistically. For example, when, based on the syllogism “(I) all humans are animals, (II) Zayd is a human, and therefore (III) Zayd is an animal” one knows that ‘Zayd is an animal,’ one knows it universally. Secondly, on the basis of the first step, Adamson tries to show how we should interpret Avicenna’s theory. The upshot of Adamson’s interpretation is that God knows only essential features of particulars and not their accidental features. In this paper, I will argue that both steps in Adamson’s account of Avicenna’s theory of God’s knowledge of particulars face serious problems. (shrink)

Michael E. Marmura, an outstanding Avicenna scholar, has presented a special interpretation of Avicenna’s view concerning God’s knowledge of particulars. In this paper, which consists of two parts, we will examine his interpretation of Avicenna. In the first part, we briefly present Marmura’s reading of Avicenna’s theory of God’s knowledge of particulars. According to Marmura’s interpretation of Avicenna, God only knows, individually, particular entities which are the only member of their species. Also, He knows, individually, particular events which are attributed (...) to such particular entities. Arguing that Avicenna’s theory is not able to explain God’s knowledge of ‘all’ particulars, Marmura concludes that Avicenna ‘believed’ that God does not know all particulars individually. In the second part, we will object his interpretation. The most important criticisms are as follows: he has not determined what problems Avicenna’s theory aims to solve; he has not touched two important elements of Avicenna’s theory, i.e., God’s knowledge of particulars by means of their forms, and God’s knowledge of particulars by means of His causal relation with them; and he presents an erroneous interpretation of Avicenna’s use of the eclipse example. (shrink)

Maternal opioid use during pregnancy is a growing national problem and can lead to newborns developing neonatal opioid withdrawal syndrome soon after birth. Recent data demonstrates that nearly every 15 min a baby is born in the United States suffering from NOWS. The primary treatment for NOWS is opioid replacement therapy, commonly oral morphine, which has neurotoxic effects on the developing brain. There is an urgent need for non-opioid treatments for NOWS. Transcutaneous auricular neurostimulation, a novel and non-invasive form of (...) electrostimulation, may serve as a promising alternative to morphine. tAN is delivered via a multichannel earpiece electrode worn on and around the left ear, targeting two cranial nerves—the vagus and trigeminal nerves. Prior research suggests that auricular neurostimulation exerts an anxiolytic effect on the body by releasing endogenous opioids and reduces withdrawal symptoms in adults actively withdrawing from opioids. In this first-in-human prospective, open-label trial, we investigated tAN as an adjuvant to morphine therapy in eight infants >33 weeks gestational age suffering from NOWS and receiving oral morphine treatment. Infants received tAN for 30 min 1 h before receiving a morphine dose. tAN was delivered at 0.1 mA below perception intensity at two different nerve targets on the ear: Region 1, the auricular branch of the vagus nerve; and Region 2, the auriculotemporal nerve. tAN was delivered up to four times daily for a maximum of 12 days. The primary outcome measures were safety [heart rate monitoring, Neonatal Infant Pain Scale, and skin irritation] and morphine length of treatment. tAN was well-tolerated and resulted in no unanticipated adverse events. Comparing to the national average of 23 days, the average oral morphine LOT was 13.3 days and the average LOT after tAN initiation was 7 days. These preliminary data suggest that tAN is safe and may serve as a promising alternative adjuvant for treating NOWS and reducing the amount of time an infant receives oral morphine. (shrink)

In this paper, a proof-theoretic method to prove uniform Lyndon interpolation for non-normal modal logics is introduced and applied to show that the logics E\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathsf {E}$$\end{document}, M\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathsf {M}$$\end{document}, MC\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathsf {MC}$$\end{document}, EN\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathsf {EN}$$\end{document}, MN\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathsf {MN}$$\end{document} have that (...) property. In particular, these logics have uniform interpolation. Although for some of them the latter is known, the fact that they have uniform Lyndon interpolation is new. Also, the proof-theoretic proofs of these facts are new, as well as the constructive way to explicitly compute the interpolants that they provide. It is also shown that the non-normal modal logics EC\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathsf {EC}$$\end{document} and ECN\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathsf {ECN}$$\end{document} do not have Craig interpolation, and whence no uniform interpolation. (shrink)

It is a well-known fact that although the poset of open sets of a topological space is a Heyting algebra, its Heyting implication is not necessarily stable under the inverse image of continuous functions and hence is not a geometric concept. This leaves us wondering if there is any stable family of implications that can be safely called geometric. In this paper, we will first recall the abstract notion of implication as a binary modality introduced in Akbar Tabatabai (Implication via (...) spacetime. In: Mathematics, logic, and their philosophies: essays in honour of Mohammad Ardeshir, pp 161–216, 2021). Then, we will use a weaker version of categorical fibrations to define the geometricity of a category of pairs of spaces and implications over a given category of spaces. We will identify the greatest geometric category over the subcategories of open-irreducible (closed-irreducible) maps as a generalization of the usual injective open (closed) maps. Using this identification, we will then characterize all geometric categories over a given category $${\mathcal {S}}$$ S, provided that $${\mathcal {S}}$$ S has some basic closure properties. Specially, we will show that there is no non-trivial geometric category over the full category of spaces. Finally, as the implications we identified are also interesting in their own right, we will spend some time to investigate their algebraic properties. We will first use a Yoneda-type argument to provide a representation theorem, making the implications a part of an adjunction-style pair. Then, we will use this result to provide a Kripke-style representation for any arbitrary implication. (shrink)

Trehalose is a natural disaccharide with a remarkable ability to stabilize biomolecules. In recent years, trehalose has received growing attention as a neuroprotective molecule and has been tested in experimental models for different neurodegenerative diseases. Although the underlying neuroprotective mechanism of trehalose's action is unclear, one of the most important hypotheses is autophagy induction. The chaperone‐like activity of trehalose and the ability to modulate inflammatory responses has also been reported. There is compelling evidence that the dysfunction of autophagy and aggregation (...) of misfolded proteins contribute to the pathogenesis of Alzheimer's disease (AD) and other neurodegenerative disorders. Therefore, given the linking between trehalose and autophagy induction, it appears to be a promising therapy for AD. Herein, the published studies concerning the use of trehalose as a potential therapy for AD are summarized, providing a rationale for applying trehalose to reduce Alzheimer's pathology. (shrink)

Euthanasia is one of the most controversial issues in medical ethics and one of the ten major ethical challenges in medicine and health sciences. The present study was conducted to evaluate the relationship between moral sensitivity and attitudes toward euthanasia among nursing students at Birjand University of Medical Sciences in 2020. Birjand University of Medical Sciences has four nursing schools. Cluster sampling method was used for selection of samples. After sampling Ferdows nursing school was selected. Nursing students of Ferdows School (...) were 156 person which 144 participated in the study based on inclusion and exclusion criteria. Students completed demographic information questionnaire, moral sensitivity questionnaire and euthanasia attitude questionnaire. Data were entered into SPSS software version 19 using descriptive and inferential statistical methods. Findings of this study showed that among nursing students, the mean score of moral sensitivity was 59.59 ± 11.21 and was moderate. The mean score of attitudes towards euthanasia was 0.981 ± 0.336. In addition, according to the results, correlation test showed that there is a significant direct but weak relationship between moral sensitivity and attitude to euthanasia in students. According to the findings of the present study, moral sensitivity as a scientific concept is one of the determining factors in attitudes toward euthanasia, but other factors can also affect nurses' attitudes toward euthanasia, which should be investigated and determined in future research. (shrink)

From the Qur'an, Surah Maryam: -/- (21) So she conceived him, and went in seclusion with him to a remote place. (22) And the pains of childbirth drove her to the trunk of a palm tree: she cried (in her anguish): "Ah! would that I had died before this! Would that I had been a thing forgotten and out of sight!" (23) But (a voice) cried to her from beneath the (palm tree): "Grieve not! for thy Lord hath provided a (...) rivulet beneath thee;" (24) "And shake towards thyself the trunk of the palm tree: it will let fall fresh ripe dates upon thee." (25) "So eat and drink and cool (thine) eye. And if thou dost see any man say 'I have vowed a fast to (Allah) Most Gracious, and this day will I enter into no talk with any human being.'" -/- This Surah depicts a human being in unbearable pain. What makes the pain tolerable is the sympathy that God shows for Mary. Hearing her inner voice, understanding her suffering and her grief, God is moved to provide her with practical and substantive support to help her bear her agony. For me this story portrays a God who is active in the world, hears the supplications of humanity, and has empathy with the needy, the oppressed, and those who are suffering. -/- Yet I am concerned that our theological traditions in the Islamic world (as also in Christendom) have developed through the centuries such that God is now seen, by overwhelming theological consensus, as an immutable being, a being outside time who has determined our providence from the standpoint of eternity, who has foreknowledge of every free action of his creations and has designed all according to His plan for past and future events; who knows in advance even the timings and contents of our petitionary prayers and has decided already whether to answer them. (shrink)