Perceptual experiences justify beliefs—that much seems obvious. As Brewer puts it, “sense experiential states provide reasons for empirical beliefs” (this volume, xx). In Mind and World McDowell argues that we can get from this apparent platitude to the controversial claim that perceptual experiences have conceptual content: [W]e can coherently credit experiences with rational relations to judgement and belief, but only if we take it that spontaneity is already implicated in receptivity; that is, only if we take it that experiences have (...) conceptual content. (1994, 162) Brewer agrees. Their view is sometimes called conceptualism; nonconceptualism is the rival position, that experiences have nonconceptual content. One initial obstacle is understanding what the issue is. What is conceptual content, and how is it different from nonconceptual content? Section 1 of this paper explains two versions of each of the rival positions: state (non)conceptualism and content (non)conceptualism; the latter pair is the locus of the relevant dispute. Two prominent arguments for content nonconceptualism—the richness argument and the continuity argument—both fail (section 2). McDowell’s and Brewer’s epistemological defenses of content conceptualism are also faulty (section 3). Section 4 gives a more simple-minded case for conceptualism; finally, some reasons are given for rejecting the claim—on one natural interpretation—that experiences justify beliefs. (shrink)

A survey of color science and color vision.

The Dangerous Book for Boys Abstract: Seventeenth and eighteenth century discussions of the senses are often thought to contain a profound truth: some perceptible properties are secondary qualities, dispositions to produce certain sorts of experiences in perceivers. In particular, colors are secondary qualities: for example, an object is green iff it is disposed to look green to standard perceivers in standard conditions. After rebutting Boghossian and Velleman’s argument that a certain kind of secondary quality theory is viciously circular, we discuss (...) three main lines of argument for the secondary quality theory. The first is inspired by an intuitively compelling picture of perception articulated by Reid; the second is that the secondary quality theory is a conceptual truth; the third line of argument is presented in Johnston’s influential paper ‘How to speak of the colors’. We conclude that all these arguments fail, and that the secondary quality theory is unmotivated. Keywords: color, secondary quality, disposition, vision, perception.. (shrink)

In June 2020, Gilead agreed to provide the USA with 500 000 doses of remdesivir—an antiviral drug which at that time was percieved to show promise in reducing the recovery time for patients with COVID-19. This quantity represented Gilead’s then full production capacity for July and 90% of its capacity for August and September. Similar deals are evident around access to proposed vaccines for COVID-19, and such deals are only likely to increase. These attempts to secure preferential access to medicines (...) and vaccines, so-called vaccine/treatment nationalism, jeopardise supplies of life-saving treatments and vaccines available elsewhere, and jeopardise global equitable distribution of such vaccines/treatments more generally. Much of the focus to date has been on States’ role in negotiating such deals. However, such developments also demonstrate the power patent holders have in controlling access to life-saving healthcare, determining who obtains access first and at what price. This article argues that the extent of control currently given to patent holders for COVID-19 must be questioned. This article demonstrates that patents have significant implications for healthcare acting as private governance tools over patented inventions. It is only by greater probing of patent holders’ role in delivering access to medicines, diagnostics and vaccines for COVID-19 that equitable global equitable access can be achieved. (shrink)

A survey of arguments for and against the view that colors are physical properties.

Comment on Brogaard's Seeing and Saying (OUP 2018).

There are few industries in which decisions are so intently scrutinized by millions of Canadians as the healthcare industry. Each and every day important decisions concerning the funding and delivery of healthcare are made away from the clinic and in the offices of administrators and policy makers. This book is designed to assist the current and future healthcare administrator to render effective and ethical decisions. Health administration ethics functions as a bridge between business ethics and clinical ethics. This book forges (...) the essential link between the foundational concepts of ethics theories, principles, and codes and the science of decision making. It takes a case study approach and introduces a new, user-friendly decision-making model. There is currently no Canadian textbook designed to guide administration decisions within the Canadian healthcare system, making this textbook unique in the market. (shrink)

Ficino in Spanish literaries -- Ficino as authority in sixteenth-century Spanish letters -- Ficino at Hermes Trismegistus : the Corpus Hermeticum or Pimander -- Persistence and adaptations of Hermetic-Neoplatonic imagery -- Ficino as Plato -- Persistence of political-economic Platonism.

Much of the debate about Aristotle’s criticisms of Plato has focused on the separability of the Forms. Here the dispute has to do with the ontological status of the Forms, in particular Plato’s claim for their ontological priority in relation to perceptible objects. Aristotle, however, also disputes the explanatory and causal roles that Plato claims for the Forms. This second criticism is independent of the first; even if the problem of the ontological status of the Forms were resolved to Aristotle’s (...) satisfaction, this second criticism would still stand. The problem here is not that there is no room for Aristotle’s four causes in Plato’s ontology; on the contrary, antecedents for all four can be found in Plato’s works. The problem, instead, is that Plato’s Forms fail to meet the general requirements that Aristotle sets out for the material, efficient, formal, and final causes of perceptible objects. Hence, even if the Forms were immanent in perceptible objects, they would still explain nothing about them. (shrink)

Skepticism about the internal world is actually more troubling than skepticism about the external world.

ABSTRACT Current attempts to understand unusually high rates of psychiatric illness in complex, chronic illnesses can be guilty of operating within an explanatory framework whereby there are two options. Either (a) that the psychiatric predicaments are secondary to the bodily condition, and (b) that they are primary. In this paper, I draw upon philosophical work on affect, contemporary empirical work, and qualitative first-person patient data to illustrate a much messier reality. I argue that affective experience is generally more complex in (...) such conditions, and that a variety of pre- and post-morbid causal factors dynamically interact such that the resultant psychiatric predicaments do not permit to classification as strictly primary or secondary to the bodily condition. Affective scaffolding, in my view, provides an apt theoretical framework for capturing this nuance. (shrink)

What's it all about? Why am I here? Is there a God? Why do bad things happen? What happens when we die? All the big questions - and some interesting answers - from Gay Byrne's popular TV show.

Three arguments for the thesis that sex is socially constructed are examined and rejected. No such argument could succeed, because sex is not socially constructed.

Abstract Empiricist philosophers of mind have long maintained that the possession conditions of many concepts include recognitional abilities. One of Jerry Fodor's recent attacks on empiricist semantics proceeds by attempting to demonstrate that there are no such, ?recognitional? concepts. His argument is built on the claim that if there were such concepts, they would not compose: i.e., they would exhibit properties which are not in general ?inherited? by complex concepts of which they are components. Debate between Fodor and his critics (...) on this issue has focused on his construal of compositionality, the critics in effect advocating a weaker conception than that assumed by Fodor. I argue that the critics' contention is under-motivated, and in the current context ad hoc. But there is something else wrong with Fodor's argument. He misidentifies the notion of recognitionality in which the empiricist should trade. A proper understanding of recognitionality allows us to disarm Fodor's argument without resolving the question about compositionality that divides Fodor and his critics. I end with two very general remarks. First a contention about the motivation for empiricist semantics, and second, a suggestion that my proposal about recognitionality may be extended to disarm a more familiar and influential type of concern about their viability. (shrink)

Siegel and Byrne debate whether perceptual experiences present rich properties or exclusively thin properties.

argument fails, and the purpose of this note is to bring out that failure. The view in question which Heck calls the Hybrid Vie~istinguishes between the meanings of names and the contents of beliefs which are expressible using names. According to the Hybrid View the meaning of a name is its referent: names do not have senses. Thus (a) "George Orwell wrote 1984" means the same as (b) "Eric Blair wrote 1984". However, the Hybrid View tells a different story about (...) the beliefs one expresses when one utters (a) or (b). The content of a belief expressed using a sentence that contains a name has more to it than just the referent of the name and whatever properties the sentence ascribes to the name's referent. There is.. (shrink)

Abstract: We examine how trustworthy behaviour can be achieved in the financial sector. The task is to ensure that firms are motivated to pursue long-term interests of customers rather than pursuing short-term profits. Firms’ self-interested pursuit of reputation, combined with regulation, is often not sufficient to ensure that this happens. We argue that trustworthy behaviour requires that at least some actors show a concern for the wellbeing of clients, or a respect for imposed standards, and that the behaviour of these (...) actors is copied in such a way that it becomes a behavioural norm. We briefly suggest what such behavioural norms might need to be if trustworthy behaviour is to be achieved, and consider how they might be supported; we describe the research that is necessary in order to understand these norms in more detail. We argue that the norms of traders are different from the norms of those engaged in other activities, since they are inevitably self-interested, and we consider the risk that traders’ norms might undermine those of other actors. We analyse the task for governance in dealing with this problem, and the role which leadership by a corporate board and management might play in doing this. We describe the need for further research in to describe how this might be done. (shrink)

Energy efficiency and energy security are emerging concerns in climate change policy. But. there is little acknowledgment of energy justice issues. Marginalised and vulnerable communities may be disproportionately exposed to both climate change impacts (e.g. heat, flooding) and costs associated with energy transitions related to climate change mitigation and adaptation (e.g. particulate exposure from biofuel combustion). Climate change is producing energy-related impacts such as increased cooling costs. In some cases it threatens energy security. Higher electricity costs associated with ‘climate proofing’ (...) energy network infrastructure may exacerbate ‘fuel poverty’ - itself a form of injustice. In this paper we critically review the literature about multiple interrelations between energy policy, justice and climate change. We identify key issues, illuminate knowledge gaps, and synthesise findings to develop a conceptual model. We chart a research agenda and highlight policy implications. (shrink)

This article outlines and compares current and proposed global institutional mechanisms to increase equitable access to COVID-19 vaccines, focusing on their institutional and operational complementarities and overlaps. It specifically considers the World Health Organization's (WHO’s) COVAX (COVID-19 Vaccines Global Access) model as part of the Access to COVID-19 Tools Accelerator (ACT-A) initiative, the WHO’s COVID-19 Technology Access Pool (C-TAP) initiative, the proposed TRIPS (Trade-Related Aspects of Intellectual Property Agreement) intellectual property waiver and other proposed WHO and World Trade Organization technology (...) transfer proposals. We argue that while various individual mechanisms each have their specific individual merits—and in some cases weaknesses—overall, many of these current and proposed mechanisms could be highly complementary if used together to deliver equitable global access to vaccines. Nonetheless, we also argue that there are risks posed by the proliferation of proposals in this context, including the potential to disperse stakeholder attention or to delay decisive action. Therefore, we argue that there is now a clear need for concerted global multilateral action to recognise the complementarities of specific models and to provide a pathway for collaboration in attaining global equitable access to vaccines. The institutional infrastructure or proposals to achieve this amply exist at this point in time—but much greater cooperation from industry and clear, decisive and coordinated action from states and international organisations are urgently needed. (shrink)

This paper sets up and then solves a puzzle for the sceptical realist interpretation of Hume. The puzzle takes off when the sceptical realist attributes to Hume the following metaphysical theses: Causal powers grounding necessary connections in nature exist. Causal powers grounding necessary connections in nature are what make things happen.It then attributes an epistemological thesis to him: We have no knowledge of causal powers in nature nor of the necessary connections in nature which these powers ground.But putting these three (...) theses together seems to yield a problematic result. The epistemological thesis seems to have two corollaries as its upshot. We cannot know that causal powers grounding necessary connections in nature exist. We cannot know that causal powers grounding necessary connections in nature are what make things happen.That is, we cannot know and. New Hume’s position, the sceptical realist interpretation, seems to make Hume out to be arguing for a view that is self-undermining or dialectically unstable by his own empiricist lights. I argue that there is an overlooked externalist dimension to Hume’s epistemology and draw on this to solve the puzzle. (shrink)

Offers a vision of wholeness for approaching human ethical responses to what science is telling us about the crises facing our environment and climate.

The transition to twenty-first century post-industrial capitalism from the 'welfare' industrial capitalism of the twentieth century, has affected the ways in which class is lived in terms of relational inequality and the factors that structure identity. Class After Industry takes a complex realist approach to the dynamics of individual lives, places, the social structure and analyses their significance in terms of class. A wide range of quantitative and qualitative studies are drawn on to explore how 'life after industry' shapes class, (...) and the consequent potential for social change. The book will be of interest across the social sciences and beyond, to those concerned with how class forms might translate into political action. (shrink)

This essay comprises a first phenomenological semiotics of ChatGPT. I analyse how we experience the language signs generated by that AI. This task is accomplished in two steps. First, I introduce a conceptual scaffolding for the project, by introducing core tenets of Husserl's semiotics. Second, I mould Husserl's theory to develop my phenomenology of the passive and active consciousness of the language signs composed by ChatGPT. On the one hand, by discussing temporality, I demonstrate that ChatGPT can passively demand me (...) to understand its signs. On the other hand, I show that a conflict arises between active and passive consciousness when reading ChatGPT. While I actively know that there is no communicating subject, I still passively experience these signs as made by another. I argue that it is this conflict which lends ChatGPT its 'magical' character. I conclude by showing how these observations can inform future regulation of AI models. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:A Humanist History of Mathematics?Regiomontanus's Padua Oration in ContextJames Steven ByrneIn the spring of 1464, the German astronomer, astrologer, and mathematician Johannes Müller (1436–76), known as Regiomontanus (a Latinization of the name of his hometown, Königsberg in Franconia), offered a course of lectures on the Arabic astronomer al-Farghani at the University of Padua. The only one of these to survive is his inaugural oration on the history and utility (...) of the mathematical arts.1 Regiomontanus tells his audience that the purpose of the oration is torelate first the origin of our arts, and among which nations they first began to be cultivated, in what way they were at last translated from various foreign tongues into Latin, which of our ancestors were famed in these disciplines, and to whom in our lifetimes recognition should be granted.2To this end, he offers a history of the quadrivial arts (arithmetic, geometry, music, and astronomy) and other important mathematical disciplines from [End Page 41] antiquity to his own time, praises their utility, and exhorts his audience to revive the languishing study of mathematics at Padua. Astrology, a discipline with which Regiomontanus himself was closely associated, is singled out for particular praise.Traditionally, Regiomontanus's Padua oration has been seen through the lens of its rather obvious humanism. In particular, the Padua oration has come to be understood as the rhetorical embodiment of the fifteenth-and-sixteenth-century revival of ancient (Greek) mathematics. Just as this revival is inextricable from the rise of humanism, so Regiomontanus has come to be seen as an exemplar of humanist mathematics.3 It is the aim of this paper to examine the Padua oration in the context both of contemporary humanist rhetoric and of Regiomontanus's own intellectual background in order to argue that, while the oration is stylistically consistent with humanist norms, the vision of mathematics presented in it is also deeply grounded in the university mathematical curriculum and in Regiomontanus's own reading of mathematical texts.Regiomontanus was educated primarily at the University of Vienna (he was also briefly at the University of Leipzig), where he enrolled in 1450, completed his baccalaureate in 1452 and became a master in 1457.4 He remained at Vienna until 1461, when the death of his friend and teacher Georg Peurbach prompted him to travel to Italy with his patron, Cardinal Bessarion.5 In Regiomontanus's day Vienna was probably the most important of the German universities, rivaled only by Prague, whose prestige had declined after it was stripped of its theology faculty in the aftermath of the Hussite Wars.6 The curriculum at the University of Vienna was modeled [End Page 42] after that of Paris, and Parisian scholars played a major role both in its founding in 1365 and in its re-establishment (this time with a theology faculty) in 1384.7Most importantly for the purposes of this paper, the Viennese mathematical curriculum of Regiomontanus's day included all of the traditional authorities taught at Paris in the fourteenth century. For arithmetic and algebra, various "algorisms" (prose or poetry instructions for carrying out arithmetical operations that often also included a small amount of number theory) were the basic texts, supplemented in the fourteenth century by the Quadripartitum numerorum of Jean de Murs. Jordanus de Nemorare's De numeris datis and al-Khwarizmi's Algebra were common sources for those engaged in more advanced studies (i.e., they were not normally the subject of ordinary lectures, but were readily available to interested students, and would perhaps have been the subject of occasional extraordinary lectures). Euclid's Elements, supplemented by the commentaries of Pappus and Campanus, was the central text for geometry, and a number of medieval texts on practical and speculative geometry were in circulation as well. For astronomy, the Sphere of Sacrobosco and the Theorica planetarum were the most commonly used teaching texts, sometimes supplemented by al-Farghani's Elements of Astronomy (the subject of Regiomontanus's Padua lectures). Advanced students could read numerous more specific treatises by Arabic and Latin authors. For optics, the Perspectiva communis of John Peckham was the most common basic text, with texts... (shrink)

Arguing About Language presents a comprehensive selection of key readings on fundamental issues in the philosophy of language. It offers a fresh and exciting introduction to the subject, addressing both perennial problems and emerging topics. Classic readings from Frege, Russell, Kripke, Chomsky, Quine, Grice, Lewis and Davidson appear alongside more recent pieces by philosophers or linguists such as Robyn Carston, Delia Graff Fara, Frank Jackson, Ernie Lepore & Jerry Fodor, Nathan Salmon, Zoltán Szabó, Timothy Williamson and Crispin Wright. Organised into (...) clear sections, readings have been chosen that engage with one another and often take opposing views on the same question, helping students to get to grips with the key areas of debate in the philosophy of language, including: sense and reference definite descriptions linguistic conventions language and behaviour descriptivism and rigidity contextualism vagueness rule-following and normativity fictional discourse. Each article selected is clear, thought-provoking and free from unnecessary jargon. The editors provide lucid introductions to each section in which they give an overview of the debate and outline the arguments of the papers. Arguing About Language is an ideal reader for students looking for a balanced yet up-to-date introduction to the philosophy of language. Darragh Byrne is lecturer in philosophy at the University of Birmingham, UK. Max Kölbel is ICREA Research Professor at the University of Barcelona, Spain. He is the author of Truth without Objectivity (Routledge, 2002) and co-editor of Wittgenstein's Lasting Significance (Routledge, 2004) with Bernhard Weiss, as well as Relative Truth (Oxford, 2008) with Manuel García-Carpintero. (shrink)

Anti-selection occurs when information asymmetry exists between insurers and applicants. When an applicant knows they are at high risk of loss, but the insurer does not, the applicant may try to use this knowledge differential to secure insurance at a lower premium that does not match risk.

The human body has come to be seen as forever susceptible to both external and internal hazards, which in many circumstances require immediate, heroic, and expensive intervention. In response to this, there has been a shift from a treatment‐based healthcare model to one of prevention wherein nurses play an integral role by identifying and assessing risks for individuals, communities, and populations. This paper uses Deborah Lupton’s outline of the spectrum of risk and applies the theoretical works of Foucault and Plato (...) to demonstrate the means by which nurses maintain social order by identifying and counselling risk takers. It also utilizes the work of Deleuze and Guattari to illustrate how Plato’s framework for creating social order through the creation of the good citizen can be viewed as a micro‐fascist system, which has been adopted wholeheartedly by preventative health professionals. The goal of this paper is to present an alternate understanding of risk to provide nurses and other healthcare professionals with a non‐traditional appreciation of certain aspects of their practice as researchers and clinicians. (shrink)

Philosophers are accustomed to thinking about human existence as finite and deathbound. Anne O'Byrne focuses instead on birth as a way to make sense of being alive. Building on the work of Heidegger, Dilthey, Arendt, and Nancy, O'Byrne discusses how the world becomes ours and how meaning emerges from our relations to generations past and to come. Themes such as creation, time, inheritance, birth and action, embodiment, biological determinism, and cloning anchor this sensitive and powerful analysis. O'Byrne's (...) thinking advances and deepens important discussions at the intersections of feminism, continental philosophy, philosophy of religion, and social and political thought. (shrink)

The science and technology of genetic testing is rapidly advancing with the consequences that genetic testing may well offer the prospect of being able to detect the onset of future disabilities. Some recent research also indicates that certain behavioural profiles may have a strong genetic basis, such as the determination to succeed and win or the propensity for risk-taking, which may be of interest to third parties. However, as this technology becomes more prevalent there is a danger that the genetic (...) information may be misused by entities such as employers, insurance companies, educational facilities, and finance companies and that people with particular genetic profiles may be discriminated against.This book explores the different types and the potential uses of genetic testing. The book highlights the ethical and legal dilemmas and the challenges arising as a result of emerging and rapidly advancing genetic science. Chapters in the book assess the importance and impact of the US Genetic Information Non-Discrimination Act (GINA) in the employment and health insurance contexts asking whether it is proving to be an effective tool in addressing the issue of genetic discrimination and alleviating individuals' fears of discrimination. The book then goes on to make the case for regulation at the European Union level in order to protect the privacy of genetic information and to prevent the discriminatory use of genetic information in Europe. It considers what can be learnt from the experience of the US in addressing ethical and legal issues as well as the impact that the UN Convention on the Rights of Persons with Disabilities is having on this debate within the EU. (shrink)

The application of machine learning and artificial intelligence in healthcare domains has received much attention in recent years, yet significant questions remain about how these new tools integrate into frontline user workflow, and how their design will impact implementation. Lack of acceptance among clinicians is a major barrier to the translation of healthcare innovations into clinical practice. In this systematic review, we examine when and how clinicians are consulted about their needs and desires for clinical AI tools. Forty-five articles met (...) criteria for inclusion, of which 24 were considered design studies. The design studies used a variety of methods to solicit and gather user feedback, with interviews, surveys, and user evaluations. Our findings show that tool designers consult clinicians at various but inconsistent points during the design process, and most typically at later stages in the design cycle. We also observed a smaller amount of studies adopting a human-centered approach and where clinician input was solicited throughout the design process. A third of all studies reported on clinician trust in clinical AI algorithms and tools. The surveyed articles did not universally report validation against the “gold standard” of clinical expertise or provide detailed descriptions of the algorithms or computational methods used in their work. To realize the full potential of AI tools within healthcare settings, our review suggests there are opportunities to more thoroughly integrate frontline users’ needs and feedback in the design process. (shrink)

In this study on deduction, the authors argue that people reason by imagining the relevant state of affairs, ie building an internal model of it, formulating a tentative conclusion based on this model and then searching for alternative models.

The COVID-19 pandemic has prompted unprecedented global disruption. For medical schools, this has manifested as examination and curricular restructuring as well as significant changes to clinical attachments. With the available evidence suggesting that medical students’ mental health status is already poorer than that of the general population, with academic stress being a chief predictor, such changes are likely to have a significant effect on these students. In addition, there is an assumption that these students are an available resource in terms (...) of volunteerism during a crisis. This conjecture should be questioned; however, as those engaging in such work without sufficient preparation are susceptible to moral trauma and adverse health outcomes. This, in conjunction with the likelihood of future pandemics, highlights the need for ‘pandemic preparedness’ to be embedded in the medical curriculum. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Comments on “Moral Complicity in Induced Pluripotent Stem Cell Research”W. Malcolm Byrnes, Ph.D. and Edward J. FurtonIn his article titled “Moral Complicity in Induced Pluripotent Stem Cell Research,” Mark T. Brown (2009) unfortunately mischaracterizes my ethical analysis of the use of induced pluripotent stem (iPS) cells for replacement therapies, or treatments (Byrnes 2008). In my paper, which Brown cites, I argue that, just as it is ethically acceptable for (...) parents to allow their children and themselves to be immunized using vaccines produced by cell lines derived from human fetuses aborted in the past, it is also acceptable for persons in the future to benefit from treatments that use iPS cells validated using human embryonic stem (ES) cell lines [End Page 202] derived in the past. The assumption I make is that iPS cells would have to be shown to be functionally equivalent to human ES cells—i.e., validated—before they could be used for cell replacement treatments. (If it turns out that this assumption is incorrect, and primate or even mouse ES cells can be used for the validation, then all residual ethical problems will disappear and there will be no ethical problems whatsoever associated with iPS cells.) I wrote:... [I]n both cases, the origin of the treatment is in a one-time event: either the one-time use of aborted fetuses to obtain cell lines (e.g., MRC-5 and WI- 38) to grow weakened virus strains for vaccine production, or the one-time destruction of human embryos to validate iPS cells, which then effectively replace embryonic stem cells. In the latter case, if no additional embryonic stem cell lines are derived, then derivation of the existing lines could be considered a “one-time” event in the past, albeit an event that extended over a several-year period(Byrnes 2008, p. 287, emphasis added).Note the phrase “if no additional embryonic stem cell lines are derived.” The derivation of ES cell lines inherently involves destruction of embryos; indeed, that is why many people, including me, are opposed to human ES cell research. In my article, I am arguing that, if no additional ES cell lines are derived, then no additional human embryos will be destroyed, and the destruction of human embryos will lie in the past. In this case, embryo destruction could be considered a past event, just as the abortion of a human fetus from which vaccine-producing cell lines were derived is a past, albeit tragic, event.In the process of building his argument that proponents of iPS cell research are morally complicit in embryo destruction, Brown (2009, p. 15) casts me as being in favor of the “derivation of new embryonic stem [cell lines].” This is the exact opposite of my position. In fact, I am opposed to further destruction of human embryos. I believe that the hundreds of ES cell lines already in existence are more than sufficient to validate iPS cells and so no additional lines need to be derived. This means that no additional human embryos will need to be destroyed.Apparently based on the misperception that I support future destruction of human embryos, Brown concludes that “Byrnes’s endorsement of ongoing iPSC validation studies would seem to implicate him and those who follow his lead in formal and material complicity in what they perceive as moral evil” (p. 16). He writes that “explicit formal complicity would attach because he [Byrnes] knowingly and intentionally recommends that embryos be killed in order to facilitate a transition to a future in which no more embryos need be destroyed” (p. 16). Additionally, my “followers” and I would be guilty of “proximate material complicity” as well as “remote material complicity” (p. 16). Unfortunately, this broad condemnation is based on a misconception of my actual position.An additional problem involves Brown’s use of a quotation he attributes to me: [End Page 203]Once embryonic stem cells are used to successfully validate iPS cells, they will no longer be needed and their association with iPS cells will lie in the past. Is there not an element of sadness and resignation in accepting something (iPS cells) associated with an unjust act (destruction of an... (shrink)