Between 1987 and 1997, Thailand experienced a bubble economy. When the bubble economy exploded in 1997, the country suddenly experienced an economic crisis: it was in heavy debt and became financially controlled by the International Monetary Fund (IMF). The problem was caused by the country’s desire to rapidly change itself from an agricultural country to an industrial one, without considering its own comparative advantage in that its climate and resources are more suitable for agriculture. Thailand also wanted to become a (...) newly industrialized country and a inancial hub of Southeast Asia without considering its readiness. These ideas came to a halt after the bubble economy explosion. However, just after Thailand managed to solve its debt problem with the IMF, thegovernment once again declared its desire to turn the country into the ‘Detroit of Asia’, to develop the capital, Bangkok, into the region’s fashion hub and to launch a substantial number of mega-projects, albeit with the existence of a widening economic gap between the rural and urban areas. This economic trend became known as “Thaksinomics” with reference to the name of the Prime Minister at that time, Thaksin Shinawatra. On the other hand, there has been a great deal of criticism of such a trend, which has been seen as a capitalist move promoting the consumerist behaviour of Thai people. There is, therefore, a call for Thai society to review itself, especially in its social and economic development aspects, and a change to a new kind of development with an emphasis on self-reliance andmoderation. This call is based on a Buddhist belief which is reflected in the old Thai way of life. This kind of economy is called “Self-Sufficiency Economy” as opposed to a capitalist-consumerist economy. It is believed that this new direction will help lay a strong foundation for the Thai economy and provide it with a high level of immunity for progress towards a more stable and sustainable economy. (shrink)

L’article cherche à préciser la conception de l’histoire à l’œuvre dans la philosophie de Léon Brunschvicg suite à quelques critiques qui lui ont été adressées. Il s’agit en particulier de soulever la question de savoir si la conception événementielle affirmée par Brunschvicg ne serait pas limitée par une logique de l’histoire et quelles seraient les conséquences de cette limite. L’article retrace l’origine de la philosophie de l’événement jusqu’à sa thèse, La modalité du jugement, où Brunschvicg présente une histoire a priori (...) du jugement. Il analyse ensuite l’histoire a posteriori du jugement mathématique telle que présentée dans les Étapes de la philosophie mathématique. Il arrive à la conclusion que même s’il y a une logique de l’histoire brunschvicgienne, laquelle tend à la fois à l’unification de l’esprit et à sa prise de conscience de lui-même en tant qu’agissant, cette logique n’annule pas la dimension événementielle de l’histoire, mais la réduit seulement aux exigences de la vérité. (shrink)

Altruism can be understood in terms of traditional principles of reinforcement if an outcome that is beneficial to another person reinforces the behavior of the actor who produces it. This account depends on a generalization of reinforcement across persons and might be more amenable to experimental investigation than the one proposed by Rachlin.

Johanna Knapstein,1 Daniel Grimm,1 Marcus A Wörns,1 Peter R Galle,1 Hauke Lang,2 Tim Zimmermann111st Department of Internal Medicine, Johannes Gutenberg-University, Mainz, Germany; 2Department of General, Visceral and Transplantation Surgery, Johannes Gutenberg-University, Mainz, GermanyIntroduction: Hepatitis C virus reinfection occurs universally after liver transplantation, with accelerated cirrhosis rates of up to 30% within 5 years after liver transplantation. Dual antiviral therapy with pegylated interferon-2a and ribavirin only reaches sustained virological response rates of ~30% after liver transplantation. With the approval of viral NS3/4A (...) protease inhibitors telaprevir, boceprevir, and simeprevir and the NS5B polymerase inhibitor sofosbuvir, combination therapy offers new therapeutic options for HCV-infected patients, resulting in considerably higher sustained virological response rates in the nontransplant setting. Case presentation: We report three cases of TVR-based triple antiviral therapy in HCV genotype 1 reinfected patients after liver transplantation, of whom a 57-year-old Caucasian female and a 43-year-old Caucasian male were therapy naïve, and a 49-year-old Caucasian male patient was pretreated ineffectively. After 4 weeks of therapy, viral load decreased one to three log10 and became negative in weeks 6 to 8 in the therapy naïve patients. The pretreated patient showed a negative viral load in week 4. TVR was administered over 12 weeks, 750 mg thrice daily. Doses of immunosuppression with cyclosporine were reduced four to six fold. Initial peg-IFN and RBV doses ranged from 135–180 µg/week and 800–1,200 mg/day, according to the patient's body weight. Doses of peg-IFN and RBV were adapted to 90–135 µg/week and 400–800 mg/day after 2 to 12 weeks of protease inhibitor therapy. Dual therapy was continued for 36 weeks with total treatment duration of 48 weeks in the therapy naïve patients leading to a sustained virological response 12 weeks after the end of therapy. In the pretreated patient a breakthrough was detected in week 24 and therapy was discontinued. Overall, antiviral therapy was well tolerated. Side effects included dysgeusia and anemia leading to erythropoietin application and blood transfusions. Conclusion: This case series emphasizes that triple therapy with TVR is an efficient treatment for therapy naïve HCV genotype 1 reinfected patients after liver transplantation. But therapeutic options for pretreated patients require improvement. Keyword: cyclosporine, interferon, ribavirin, hepatitis C, protease inhibitor. (shrink)

"Aimée Pallière, Bergson et le Judaïsme" est un ouvrage écrit par Aimée Pallière, une écrivaine et mystique française du XXe siècle. Aimée Pallière était également la belle-sœur du philosophe Henri Bergson. Dans cet ouvrage, Aimée Pallière explore la relation entre Bergson, un important philosophe français, et sa propre compréhension du judaïsme. Elle examine comment les idées philosophiques de Bergson interagissent avec ses racines juives et comment cela influence sa pensée.

Avant-propos: Les corrections nécessaires au mysticisme romantique.--Le mysticisme de la race. Les plus récents théoriciens du pangermanisme.--Un débat sur le mysticisme éstht́ique: Erwin Rohde et Fréderic Nietzsche.--Une doctrine du mysticisme social. Les étapes du Marxisme.--La doctrine morale de Tolstoï.--Appendice: I. Le mysticisme passionel. II. Un nouveau mysticisme social.--Table des matières.

Félicité Robert de La Mennais serait-il le précurseur de Karl Marx? Voici la question originale que pose ici Aimé Richardt à propos d'une personnalité complexe, qui va consacrer sa vie à la défense des pauvres, des humbles, des ouvriers. Celui qui avait tout d'abord défendu avec ferveur l'autorité spirituelle absolue du pape dans son Essai sur l'indifférence en matière de religion, va, en quelques années, changer radicalement. Avec Montalembert et Lacordaire, il fonde le journal L'Avenir, lieu d'expression d'un christianisme libéral (...) en gestation. Par leurs articles et leurs prises de position tranchées, ils s'attirent les foudres de Rome et du pouvoir. Condamnés par le pape Grégoire XVI, les trois hommes se séparent. Les premiers se soumettent, mais Lamennais, dans une dérive inéluctable, se révolte et rompt avec l'Eglise catholique. Il publie alors un ouvrage qui fera date : Paroles d'un croyant. Ce livre connaît un succès immédiat, en appelant à la révolte contre l'injustice au nom de l'Evangile. Il contient en germe, plus de trente ans avant Le Capital, la plupart des idées qui y seront développées. Après des aventures politiques contrastées et décevantes - député de gauche à l'Assemblée nationale de 1848 -, Lamennais meurt dans la pauvreté, à Paris, hors de l'Eglise. Replongeant dans les écrits et la correspondance de Lamennais, Aimé Richardt le suit pas à pas dans ses combats et ses révoltes, jusqu'à la fosse commune du Père-Lachaise, où fut déposé son corps le 1er mars 1854. (shrink)

Estonia is a democratic, parliamentary republic with a health care system that is built on the principle of compulsory, solidarity-based insurance and the all-round availability of services of private service providers. Estonia has specific biobank legislation as well as oversight via data protection laws. Its population-based biobank, the Estonian Genome Center, established in 2001, is one of the largest biobanks in Europe, and its database may be used only for scientific research, public health research, and statistics. The EGCUT can issue (...) data to a third party, but only in coded form. This comprehensive database of genotypic, phenotypic, health, and genealogical information represents about 5% of Estonia's adult population, and is the largest cohort ever gathered in Estonia. Government approval is required for international data sharing, and sharing can be further limited by the requirement of ethics approval and permission from Estonian government. (shrink)

L'expérimentation de nouvelles formes de communication politique conduit souvent à regarder l'interner comme un lieu de parole et de dialogue. Mais les médias informatisés sont aussi, et avant tout, un lieu où se définissent les objets et les postures politiques. En particulier, la volonté de mettre à disposition les éléments d'un débat possible tourne souvent à la mise en visibilité, moins de la parole, que de sa possibilité. Car cette thématique de la parole libérée dissimule la réalité d'un ensemble de (...) formes écrites et documentaires, arrière-plan de la discussion qui va jusqu'à se substituer à elle.Experimenting with new forms of communication often leads to watching the intern as a place of speech and dialogue. But the media are also computerized and, above all, a place to define the objects and political posturing. In particular, the desire to provide the elements of a possible debate often turns to set visibility, less speech than of its possibility. For this theme speech released conceals the reality of a set of written forms and documentary background to the discussion that will take its place. (shrink)

This study is concerned with the placement of the secondary stress in Tiberian Biblical Aramaic. The challenging aspect of this placement is that, contrary to universal typology, both long-voweled CVVC, CVV and short-voweled CV syllables are stressed whereas short-voweled CVC syllables are not. This apparently abnormal distribution is rationalized by arguing that CV syllables became CVV due to a secondary lengthening of the short vowel. I claim that this lengthening is a late development and likely corresponds to the late orthographical (...) practice of regularly marking the secondary stress on open syllables. A similar lengthening in Eastern Syriac offers support for this interpretation. Finally, the common origin of Biblical Hebrew and Biblical Aramaic secondary stresses is briefly discussed. (shrink)