Evolutionary psychology and human sociobiology often reject the mere possibility of symbolic causality. Conversely, theories in which symbolic causality plays a central role tend to be both anti-nativist and anti-evolutionary. This article sketches how these apparent scientific rivals can be reconciled in the study of disgust. First, we argue that there are no good philosophical or evolutionary reasons to assume that symbolic causality is impossible. Then, we examine to what extent symbolic causality can be part of the theoretical toolbox of (...) the evolutionary social sciences. This examination leads to the conclusion that it is possible to make evolutionary sense of Mary Douglas’s theory of disgust, and that her view of symbolic causality can and should inform evolutionary theories of (sociocultural) disgust. (shrink)

Volume 19, Issue 12, December 2019, Page 51-54.

The crisis in donor organ and tissue supply is one of the most difficult challenges for transplant today. New policy initiatives, such as the driver's license option and requiredrequest, have been implemented in many states, with other initiatives, such as mandatedchoice and presumedconsent, proposed in the hopes of ameliorating this crisis. At the same time, traditional acquisition of organs from human cadavers has been augmented by living human donors, and nonheartbeating human donors, as well as experimental animal and artificial sources. (...) Despite these efforts, the crisis persists and is perhaps most tragic when it threatens the lives of children, driving parents to sometimes desperate measures. Herein, we address one very controversial step some parents have taken to obtain matching tissue or organs for their needy children—that is, having a child, in part, for the purpose of organ or tissue procurement. (shrink)

As Part of the Omnibus Budget Reconciliation Act of 1990, the Patient Self Determination Act legislates new responsibilites for healthcare facilities. The authors served as members of the California Consortium on Patient Self-Determination, and the materials produced by this group offer healthcare facilities a valuable guide for implementing the PSDA. The ACt follows a historical trend led by doctrines of informed consent and increasing patient autonomy regarding rights to accept or refuse medical treatment and to execute advance directives. The requirements (...) of the Act will influence healthcare facilities and how they communicate with patients about advance directives. Although the Act seeks to increase awareness of advance directices among all participants in healthcare interactions, it could pose major stumbling blocks to providing sensitive and humane care if certain concerns are nor addressed adequatley. The benefits of the Act could be far reaching and substantial for patients and healthcare facilities alike. (shrink)

Transoral laser microsurgery applies to the piecemeal removal of malignant tumours of the upper aerodigestive tract using the CO2 laser under the operating microscope. This method of surgery is being increasingly popularised as a single modality treatment of choice in early laryngeal cancers (T1 and T2) and occasionally in the more advanced forms of the disease (T3 and T4), predomi- nantly within the supraglottis. Thomas Kuhn, the American physicist turned philosopher and historian of science, coined the phrase ‘paradigm shift’ in (...) his groundbreaking book The Structure of Scientific Revolutions. He argued that the arrival of the new and often incompatible idea forms the core of a new paradigm, the birth of an entirely new way of thinking. This article discusses whether Steiner and col- leagues truly brought about a paradigm shift in oncological surgery. By rejecting the principle of en block resection and by replacing it with the belief that not only is it oncologically safe to cut through the substance of the tumour but in doing so one can actually achieve better results, Steiner was able to truly revolutionise the man- agement of laryngeal cancer. Even though within this article the repercussions of his insight are limited to the upper aerodigestive tract oncological surgery, his willingness to question other peoples’ dogma makes his contribution truly a genuine paradigm shift. (shrink)

A milestone in Wittgenstein scholarship, this collection of essays ranges over a wide area of the philosopher's thought, presenting divergent interpretations of his fundamental ideas. Different chapters raise many of the central controversies that surround current understanding of the Tractatus, providing an interplay that will be particularly useful to students. Taken together, the essays present a broader and more comprehensive view of Wittgenstein's intellectual interests and his impact on philosophy than may be found elsewhere.The thirteen chapters treat topics from both (...) periods of Wittgenstein's work: More than half are devoted to his early thought, the Tractatus Logico-Philosophicus of 1921, reflecting a growing interest today among philosophers in reexamining this seminal book, while three chapters treat the Philosophical Investigations, published posthumously in 1953. The remaining chapters discuss such "nonstandard" topics as philosophy of religion, aesthetics, and anthropology.Contents: The Early Wittgenstein and the Middle Russell, Kenneth Blackwell; Frege and Wittgenstein, Michael Dummett; Wittgenstein and the Theory of Types, Hide Ishiguro; The So-called Realism of Wittgenstein's Tractatus, Brian McGuinness; The Logical Independence of Elementary Propositions, David Pears; The Rise and Fall of the Picture Theory, Peter Hacker; The Picture Theory and Wittgenstein's Later Attitude to It, Erik Stenius; Wittgenstein's Early Philosophy of Mind, Anthony Kenny; A Theory of Language?, G. E. M. Anscombe; Im Anfang war die Tat, Peter Winch; Wittgenstein's Full Stop, D. Z. Phillips; Quote: Judgments from Our Brain, Paul Ziff; Wittgenstein and the Fire Festivals, Frank Cioffi, Index.Irving Block is Associate Professor in the Philosophy Department at The University of Western Ontario. (shrink)

Little is known about distance processing in patients with posterior brain damage. Although many investigators have claimed that distance estimates are normal or abnormal in some of these patients, many of these observations were made informally and the examiners often asked for relative, and not absolute, distance estimates. The present investigation served two purposes. First, we wanted to contrast the use of distance information in peripersonal space for perceptual report as opposed to visuomotor control in our visual form agnosic patient, (...) DF. Second, we wanted to see to what extent her abilities to process distance cues were dependent on binocular vision, in light of Milner et al.'s (1991) observations of preserved stereopsis in DF, and Dijkerman et al.'s (1996) and Marotta et al.'s (1997) observations that her visual guidance of grasping may be particularly dependent on binocular vision of the target. We hypothesized that DF's visuomotor responses would show normal sensitivity to target distance, while her perceptual estimates would not. In the first experiment, we required DF and two age- and sex-matched control subjects to reach out and grasp black cubes placed at varying distances, or to estimate the distance of the cubes from the hand starting position without making a reaching movement. In the second experiment, we required DF and two age-matched control subjects to point as rapidly and accurately as possible to small LED targets which differed in spatial location, under binocular and monocular conditions. The results showed that, relative to the control subjects, DF's grasping movements produced normal peak velocity-distance scaling-when she reached for blocks which varied in depth or pointed to LED targets which were presented at different distances in depth. In contrast, in the cube experiment, her verbal estimates of object distance were poorly scaled, although they improved slightly under the binocular conditions. The results are discussed in terms of current theories of processing streams in extrastriate visual cortex and the distinction between categorical and coordinate spatial processing. (shrink)

The explanatory gap . Consciousness is a mystery. No one has ever given an account, even a highly speculative, hypothetical, and incomplete account of how a physical thing could have phenomenal states. Suppose that consciousness is identical to a property of the brain, say activity in the pyramidal cells of layer 5 of the cortex involving reverberatory circuits from cortical layer 6 to the thalamus and back to layers 4 and 6,as Crick and Koch have suggested for visual consciousness. .) (...) Still, that identity itself calls out for explanation! Proponents of an explanatory gap disagree about whether the gap is permanent. Some say that we are like the scientifically naive person who is told that matter = energy, but does not have the concepts required to make sense of the idea. If we can acquire these concepts, the gap is closable. Others say the gap is uncloseable because of our cognitive limitations. Still others say that the gap is a consequence of the fundamental nature of consciousness. (shrink)

Sensorimotor learning refers to improvements that occur through practice in the performance of sensory-guided motor behaviors. Leveraging novel technical capabilities of an immersive virtual environment, we probed the component kinematic processes that mediate sensorimotor learning. Twenty naïve subjects performed a simulated marksmanship task modeled after Olympic Trap Shooting standards. We measured movement kinematics and shooting performance as participants practiced 350 trials while receiving trial-by-trial feedback about shooting success. Spatiotemporal analysis of motion tracking elucidated the ballistic and refinement phases of hand (...) movements. We found systematic changes in movement kinematics that accompanied improvements in shot accuracy during training, though reaction and response times did not change over blocks. In particular, we observed longer, slower, and more precise ballistic movements that replaced effort spent on corrections and refinement. Collectively, these results leverage developments in immersive virtual reality technology to quantify and compare the kinematics of movement during early learning of full-body sensorimotor orienting. (shrink)

The complex hexaploid wheat genome offers many challenges for genomics research. Expressed sequence tags facilitate the analysis of gene-coding regions and provide a rich source of molecular markers for mapping and comparison with model organisms. The objectives of this study were to construct a high-density EST chromosome bin map of wheat homoeologous group 2 chromosomes to determine the distribution of ESTs, construct a consensus map of group 2 ESTs, investigate synteny, examine patterns of duplication, and assess the colinearity with rice (...) of ESTs assigned to the group 2 consensus bin map. A total of 2600 loci generated from 1110 ESTs were mapped to group 2 chromosomes by Southern hybridization onto wheat aneuploid chromosome and deletion stocks. A consensus map was constructed of 552 ESTs mapping to more than one group 2 chromosome. Regions of high gene density in distal bins and low gene density in proximal bins were found. Two interstitial gene-rich islands flanked by relatively gene-poor regions on both the short and long arms and having good synteny with rice were discovered. The map locations of two ESTs indicated the possible presence of a small pericentric inversion on chromosome 2B. Wheat chromosome group 2 was shown to share syntenous blocks with rice chromosomes 4 and 7. (shrink)

This is a charming and engaging book that combines careful attention to the phenomenology of experience with an appreciation of the psychology and neuroscience of perception. In some of its aimsfor example, to show problems with a rigid version of a view of visual perception as an inverse optics process of constructing a static 3-D representation from static 2-D information on the retina--it succeeds admirably. As No points out, vision is a process that depends on interactions between the perceiver and (...) the environment and involves contributions from sensory systems other than the eye. He is at pains to note that vision is not passive. His analogy with touch is to the point: touch involves skillful probing and movement, and so does vision, although less obviously and in my view less centrally so. This much is certainly widely accepted among vision scientistsalthough mainstream vision scientists (represented, for example, by Stephen Palmers excellent textbook²) view these points as best seen within a version of the inverse optics view that takes inputs as non-static and as including motor instructions (for example, involving eye movements and head movements).³ The kind of point that No raises is viewed as important at the margins, but as not disturbing the main lines of the picture of vision that descendswith many changesfrom the pioneering work of David Marr in the 1980s (and before him, from Helmholtz). But No shows little interest in mainstream vision science, focusing on non-mainstream ideas in the science of perception, specifically ideas from the anti-representational psychologist J.J. Gibson, and also drawing on Wittgenstein and the phenomenology tradition. There is a sense throughout the book of revolution, of upsetting the applecart. This is a review from the point of view of the applecart. (shrink)

To localize wheat ESTs on chromosomes, 882 homoeologous group 6-specific ESTs were identified by physically mapping 7965 singletons from 37 cDNA libraries on 146 chromosome, arm, and sub-arm aneuploid and deletion stocks. The 882 ESTs were physically mapped to 25 regions flanked by 23 deletion breakpoints. Of the 5154 restriction fragments detected by 882 ESTs, 2043 were localized to group 6 chromosomes and 806 were mapped on other chromosome groups. The number of loci mapped was greatest on chromosome 6B and (...) least on 6D. The 264 ESTs that detected orthologous loci on all three homoeologs using one restriction enzyme were used to construct a consensus physical map. The physical distribution of ESTs was uneven on chromosomes with a tendency toward higher densities in the distal halves of chromosome arms. About 43% of the wheat group 6 ESTs identified rice homologs upon comparisons of genome sequences. Fifty-eight percent of these ESTs were present on rice chromosome 2 and the remaining were on other rice chromosomes. Even within the group 6 bins, rice chromosomal blocks identified by 1-6 wheat ESTs were homologous to up to 11 rice chromosomes. These rice-block contigs were used to resolve the order of wheat ESTs within each bin. (shrink)

Previous research suggests that children can infer causal relations from patterns of events. However, what appear to be cases of causal inference may simply reduce to children recognizing relevant associations among events, and responding based on those associations. To examine this claim, in Experiments 1 and 2, children were introduced to a “blicket detector,” a machine that lit up and played music when certain objects were placed upon it. Children observed patterns of contingency between objects and the machine's activation that (...) required them to use indirect evidence to make causal inferences. Critically, associative models either made no predictions, or made incorrect predictions about these inferences. In general, children were able to make these inferences, but some developmental differences between 3- and 4-year-olds were found. We suggest that children's causal inferences are not based on recognizing associations, but rather that children develop a mechanism for Bayesian structure learning. Experiment 3 explicitly tests a prediction of this account. Children were asked to make an inference about ambiguous data based on the base rate of certain events occurring. Four-year-olds, but not 3-year-olds were able to make this inference. (shrink)

Apoptotic pathways have always been regarded as a key‐player in preserving tissue and organ homeostasis. Excessive activation or resistance to activation of cell death signaling may indeed be responsible for several mechanisms of disease, including malignancy and chronic degenerative diseases. Therefore, targeting apoptotic factors gained more and more attention in the scientific community and novel strategies emerged aimed at selectively blocking or stimulating cell death signaling. This is also the case for the TMEM219 death receptor, which is activated by a (...) circulating ligand, the Insulin‐like growth factor binding protein 3 (IGFBP3) and induces a caspase‐8‐dependent apoptosis of the target cells. Interestingly, stimulation of the IGFBP3/TMEM219 axis exerts an anti‐proliferative effect, while blockade of the TMEM219 deleterious signal protects TMEM219‐expressing cells of the endocrine pancreas, lung, and intestine from damage and death. Here, we summarize the most updated reports on the role of the IGFBP3/TMEM219 apoptotic axis in disease conditions, including intestinal disorders and diabetes, and we describe the advancements in designing and testing novel TMEM219‐based targeting approaches in emerging potential clinical applications. (shrink)

The correct locus (or loci) of binding theory has been a matter of much discussion. Theories can be seen as varying along at least two dimensions. The rst is whether binding theory is con gurationally determined (that is, the theory exploits the geometry of a phrase marker, appealing to such purely structural notions as c-command and government) or whether the theory depends rather on examining the relations between items selected by a predicate (where by selection I am intending to cover (...) everything from semantic dependencies to syntactic subcategorization). The second is the level of grammar on which binding is de ned. Attempting to roughly equate levels across di erent theories, suggestions have included the semantics/lexical conceptual structure (Jackendo 1992), thematic structure (Jackendo 1972, Wilkins 1988), argument structure/D-structure/initial grammatical relations (Manning 1994, Belletti and Rizzi 1988, Perlmutter 1984), surface syntax/grammatical relations, logical form, linear order, pragmatics (Levinson 1991), and discourse (Iida 1992). The data is su ciently varied and complex that many theories end up as mixtures, variously employing a combination of elements along both dimensions (for instance, Chomsky (1986) relies purely on con gurational notions for the relationship between an anaphor and its antecedent, but uses concepts from selection in the de nition of the binding domain of an anaphor). LFG has always rejected a con gurational account of binding. For instancError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMapError: Illegal entry in bfrange block in ToUnicode CMape, Simpson (1991) argues that a con gurational theory of binding in Warlpiri cannot be maintained, among other reasons because nite clauses lack a VP.. (shrink)

Dual-track assessment directs research ethics committees to assess the risks of research interventions based on the unclear distinction between therapeutic and non-therapeutic interventions. The net risks test, in contrast, relies on the clinically familiar method of assessing the risks and benefits of interventions in comparison to the available alternatives and also focuses attention of the RECs on the central challenge of protecting research participants.Research guidelines around the world recognise that clinical research is ethical only when the risks to participants are (...) reasonable.1 Appropriate implementation of this requirement is vital to protecting research participants and allowing research to proceed when it poses acceptable risks. Unfortunately, as the US National Bioethics Advisory Commission notes: “current regulations do not further elaborate how risks and potential benefits are to be assessed, and little additional guidance is available to IRBs.”1The NBAC, as well as numerous commentators, recommend that research ethics committees , ethics review committees and institutional review boards should adopt what may be called dual-track risk assessment.2–5 Yet, dual-track assessment unnecessarily divides research interventions into two different categories before assessing their risks and relies on the unclear distinction between therapeutic and non-therapeutic interventions. As a result, dual-track assessment provides RECs with confusing guidance and has the potential to block valuable research that poses acceptable risks. This paper describes one alternative, the net risks test, and argues that this approach offers a better method for assessing research risks, one that puts RECs in a position to protect participants without blocking appropriate research studies.BACKGROUNDClinical research exposes participants to interventions and procedures to gather systematic data that may be used to improve overall health and well-being. To ensure that research is ethical, RECs must ensure that the risks and burdens to participants are not excessive and that …. (shrink)

This paper seeks to build on the extensive connections that have arisen between automata theory, combinatorics on words, fractal geometry, and model theory. Results in this paper establish a characterization for the behavior of the fractal geometry of “k-automatic” sets, subsets of $[0,1]^d$ that are recognized by Büchi automata. The primary tools for building this characterization include the entropy of a regular language and the digraph structure of an automaton. Via an analysis of the strongly connected components of such a (...) structure, we give an algorithmic description of the box-counting dimension, Hausdorff dimension, and Hausdorff measure of the corresponding subset of the unit box. Applications to definability in model-theoretic expansions of the real additive group are laid out as well. (shrink)

In this paper, we suggest some of the dimensions of the problematic concept of Alzheimer Disease as a natural disease discerned by increasingly sophisticated medical scientific progress. Taking a page from Max Weber concerning unique events, we show some of the conceptual building blocks and social processes that have coalesced into the perception of certain phenomena as abnormalities that are seen as implicated in the development of a degenerative disease distinct from the process of normal, but variable, brain aging. We (...) note some of the decisions and social forces pushing for particular conceptualizations, interpretations, and reifications of brain alterations. In so doing, we suggest that the mystery of the "there" may not be much different from, and probably is, the mystery of the "everywhere". (shrink)

: As the twentieth century closes, marked by triumphal strides in medical advances, the American society has yet to ensure that each person has access to affordable health care. To correct this injustice, this article calls on the nation's political and corporate leaders, providers, and faith-based groups to join all Americans in a new national conversation on systemic health care reform. The Catholic faith tradition is one that compels both a proclamation to ministry values and a commitment to speak out (...) against the challenges or threats to what are essential to the well-being of individuals and society. The Catholic health ministry must therefore be both a voice for the voiceless and an agent of transformation. The nation's goal should be to "reposition" health care from its status as an important, but ultimately optional building block to one that is essential. (shrink)

Although C. D. Broad's notion of Becoming has received a fair amount of attention in the philosophy-of-time literature, there are no serious attempts to show how to replace the standard 'block' spacetime models by models that are more congenial to Broad's idea that the sum total of existence is continuously increased by Becoming or the coming into existence of events. In the Newtonian setting Broad-type models can be constructed in a cheating fashion by starting with a Newtonian block (...) model, carving chips off the block, and assembling the chips in an appropriately structured way. However, attempts to construct Broad-type models in a non-cheating fashion reveal a number of problematic aspects of Becoming that have not received adequate attention in the literature. The paper then turns to an assessment of the problem and prospects of adapting Becoming models to relativistic spacetimes. The results of the assessment differ in both minor and major ways from the ones in the extant literature. Finally, the paper describes how the causal set approach to quantum gravity promises to provide a mechanism for realizing Becoming, though the form of Becoming that emerges may not conform to any of the versions discussed in the philosophical literature. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Witness of the Body: The Past, Present, and Future of Christian Martyrdom ed. by Michael L. Budde and Karen ScottElizabeth Sweeny BlockWitness of the Body: The Past, Present, and Future of Christian Martyrdom Edited by Michael L. Budde and Karen Scott Grand Rapids, Mich.: Eerdmans, 2011. 238 pp. $22.00In Michael L. Budde’s introduction to this volume, he asserts its twofold purpose: to identify criteria for distinguishing authentic Christian (...) martyrdom from inauthentic and to return martyrdom to a more central place in Christian life. This collection of essays—some of which were presented as part of a lecture series at DePaul University during the 2006–7 academic year—aspires to reconsider and redefine martyrdom in order to remove both the “freak-show element” and the “heroic exceptionality” associated with martyrdom in modern culture (viii). The goal of the volume, which is part of the Eerdmans Ekklesia Series, is to resituate martyrdom within the everyday life of the church, and the majority of the essays argue for the ongoing significance of a revised martyrdom for this distinctive community. These eleven essays are as much about martyrs themselves as they are about how martyrdom is perceived, received, and remembered. The interdisciplinary volume [End Page 211] is successful in encouraging a broader understanding of martyrdom, one that may not necessarily include death, and in drawing attention to the ongoing need for memorializing Christian martyrs to inspire commitment and transformation.The volume is divided into four parts representing both chronological and substantive distinctions. Part 1, “Martyrdom as the Church’s Witness,” introduces the problem of isolating the requirements of martyrdom and defining who fits into this category, a challenge addressed throughout the volume. Part 2, “Martyrdom Builds the Church,” discusses positive elements of martyrdom, especially with respect to the value of women’s bodies, drawing on both the early female martyrs in general and Joan of Arc in particular. Part 3, “Martyrdom Destroys the Church,” recounts some of the most difficult aspects of modern martyrdom, calling for a more accurate history and recognition of the emergence of a new kind of martyrdom in which one’s loyalty is to country, not faith. Part 4, “Martyrdom and the Future Church,” calls attention to the need to continue celebrating the memory of martyrs and describes the contemporary Christian martyr as a peacemaker not seeking martyrdom in the traditional sense of the word.What stands out as a theme across a number of the essays, and what I judge to be a valuable contribution to Christian ethics, is an emphasis on the way martyrs live(d), suggesting that what can and should be emulated by Christians today is a commitment to action on behalf of conversion and transformation. Tripp York’s essay rightly argues that martyrdom need not be viewed as merely reactionary, as a way of life in opposition to something, but as transformative and “for the sake of the world” (37). Michael Budde makes a similar assertion that martyrdom is better defined as deep loyalty than as treason, thereby suggesting that this kind of loyalty to Christ ought not to be limited to the special calling of a few but seen as the commitment of all Christians. Stephen Fowl’s essay conveys the meaning of the title of this volume, identifying martyrdom as part of the larger practice of “believers’ witness of the body to God’s drama of salvation” (44). He argues that in life or death, one can magnify Christ, and one’s bodily actions and responses can reflect one’s character and commitments. Emmanuel Katongole provides powerful recognition of the ways in which Christian martyrs “keep the church from sleeping” (193) and “embody the mundane gestures and practice of peaceableness in their everyday living” (199). This volume succeeds in shifting the focus from martyrdom in the traditional sense—being put to death because of one’s faith—to the ways Christians today remember, respond to, and emulate the lives and actions of martyrs. [End Page 212]Elizabeth Sweeny BlockUniversity of ChicagoCopyright © 2013 Society of Christian Ethics... (shrink)

Block's distinction between phenomenal and access consciousness is accepted, and it is agreed that one may be found without the other, but his account of the distinction is challenged. Phenomenal consciousness is perceptual consciousness, and it is a matter of gaining information of a detailed, nonverbal sort about the subject's body and environment. Access consciousness is good, old-fashioned introspection.

This book grew out of previously published papers of mine composed over a period of years; they have been reworked (sometimes beyond recognition) so as to form a reasonably coherent whole. Part One treats of informative inference. I argue (Chapter 2) that the traditional principle of induction in its clearest formulation (that laws are confirmed by their positive cases) is clearly false. Other formulations in terms of the 'uniformity of nature' or the 'resemblance of the future to the past' seem (...) to me hopelessly unclear. From a Bayesian point of view, 'learning from experience' goes by conditionalization (Bayes' rule). The traditional stum bling block for Bayesians has been to fmd objective probability inputs to conditionalize upon. Subjective Bayesians allow any probability inputs that do not violate the usual axioms of probability. Many subjectivists grant that this liberality seems prodigal but own themselves unable to think of additional constraints that might plausibly be imposed. To be sure, if we could agree on the correct probabilistic representation of 'ignorance' (or absence of pertinent data), then all probabilities obtained by applying Bayes' rule to an 'informationless' prior would be objective. But familiar contra dictions, like the Bertrand paradox, are thought to vitiate all attempts to objectify 'ignorance'. BuUding on the earlier work of Sir Harold Jeffreys, E. T. Jaynes, and the more recent work ofG. E. P. Box and G. E. Tiao, I have elected to bite this bullet. In Chapter 3, I develop and defend an objectivist Bayesian approach. (shrink)

Megastable chaotic systems are somehow the newest in the family of special chaotic systems. In this paper, a new megastable two-dimensional system is proposed. In this system, coexisting attractors are in some islands, interestingly covered by megalimit cycles. The introduced two-dimensional system has no defined equilibrium point. However, it seems that the origin plays the role of an unstable equilibrium point. Therefore, the attractors are determined as hidden attractors. Adding a forcing term to the system, we can obtain chaotic solutions (...) and coexisting strange attractors. Moreover, the effect of three different values of the forcing term’s amplitude is studied. The dynamical properties of the designed system are investigated using attractor plots, bifurcation diagrams, and Lyapunov Exponents diagram. Phase portraits of the novel megastable oscillator are presented by FPGA design. Xilinx system generator block diagrams of the proposed system and trigonometric functions are also presented. (shrink)

Phillips argues that Block faces a “serious internal challenge” in defending the claim that unconscious perception is of the same fundamental kind as conscious perception. This challenge is said to result from Block’s commitment to phenomenal overflow. However, in this paper, I demonstrate that Phillips’ rejection of overflow likewise renders his view on unconscious perception “internally challenged” and therefore equally problematic.

Prawitz has recently developed a theory of epistemic grounding that differs in many respects from his earlier semantics of arguments and proofs. An innovative approach to inferences yields a new conception of the intertwinement of the notions of valid inference and proof. We aim at singling out three reasons that may have led Prawitz to the ground-theoretic turn, i.e.: a better order in the explanation of the relation between valid inferences and proofs; a notion of valid inference based on which (...) valid inferences and proofs are recognisable as such; a reconstruction of the deductive activity that makes inferences capable of yielding justification per se. These topics are discussed by Prawitz with reference to a very general and ancient question: why and how correct deduction has the epistemic power to compel us to accept its conclusions, provided its premises are justified? We conclude by remarking that, in spite of some improvements, the ground-theoretic approach shares with the previous one a problem of vacuous validity which, as Prawitz himself points out, blocks in both cases a satisfactory explanation of epistemic compulsion. (shrink)

In this paper I respond to Robert Taylor's argument that a Rawlsian framework does not support strong affirmative action programs. The paper makes three main arguments. The first disputes Taylor's claim that strong AA would not be needed in ideal conditions. Private racial discrimination, I suggest, might still exist in such conditions, so strong AA might be needed there. The second challenges Taylor's claims that pure procedural justice constrains Rawlsian nonideal theory. I argue that this rests on a fetishizing of (...) pure procedural justice that is absent from Rawls's work. I also show that a revised formulation of Taylor's concern here also fails. My third argument makes a positive Rawlsian case for strong AA in nonideal conditions that builds on a Taylor concession. Taylor suggests that the goal of nonideal theory is to create a world in which ideal theory can be applied. My argument begins by showing that another permissible goal of Rawlsian nonideal theory is to ameliorate injustice. I then argue that Rawls's contractualist framework supports the strongest forms of AA when category 3 interventions are blocked. (shrink)

Context: The detection of objective reality, truth, and lies are still heated topics in epistemology. When discussing these topics, philosophers often resort to certain thought experiments, engaging an important concept that can be broadly identified as “the global observer.” It relates to Putnam’s God’s Eye, Davidson’s Omniscient Interpreter, and the ultimate observer in quantum physics, among others. Problem: The article explores the notion of the global observer as the guarantor of the determinability and configuration of events in the world. It (...) analyzes the consistency of the notion “global observer” from the standpoint of logic and philosophy, and discusses why application of this notion in some contexts poses challenges and appears to be paradoxical. Method: The paper uses conceptual methods of argumentation, such as logical and philosophical kinds of proof. Its key approach is the engagement of thought experiments. Results: The notion of a global observer is incoherent: “being global” and “being an observer” appear to be incompatible features. It is claimed that from the standpoint of global observation, there are no events occurring in the world. Furthermore, the indefiniteness of the world as a whole is asserted, which is related to the uninformedness of the global observer regarding the “true state of affairs.” “Global observation” turns out to be incompatible with the concept of the observer, blocking, as a result, the opportunity for a determinable configuration of events. It only makes sense to discuss local observations, which are limited to mutual observation or introspections, and not to assume the existence of some absolute truth, reality, or the state of affairs beyond the local observations. Constructivist content: The article emphasizes the role of the observer and observation. It opens up some problematic consequences of the core philosophical assumptions of globally observing existence. Referring to von Foerster’s and Luhmann’s idea that we can only speak reasonably about local observations, the paper argues that reality is neither external to nor independent of the observer. Implications: The paper could be productive for epistemic theories, theories of quantum physics, and theories of non-classical logic. (shrink)

The keystone of the system, this volume deals with the central mystery of Christianity, viz., the doctrine of Christ. The book is carefully, even beautifully written. To some, Tillich's existentializing will prove a stumbling block; to others it may make the heart of Christianity acceptable for the first time.--D. R.

Native and to some extent non-native speakers have shown processing advantages for idioms compared to novel literal phrases, and there is limited evidence that this advantage also extends to memory in L1 children. This study investigated whether these advantages generalize to recognition memory in adults. It employed a learning paradigm to test whether there is a recognition memory advantage for idioms compared to literal phrases in adult L1 and L2 learners considering both form and meaning recognition. Additionally, we asked whether (...) the presence of unfamiliar vocabulary interferes with phrasal learning by looking at recall of such unfamiliar words. When encountering new idioms, L2 learners often must cope with both figurative meaning and unfamiliar vocabulary. While single word meaning need not interfere with idiomatic meaning, it is a building block for the meaning of literal phrases. In Experiment 1, L2 learners showed equal recall for the form and meaning of literal and idiomatic phrases in which either all words were highly familiar, or one word was unfamiliar. However, unfamiliar words decreased overall recognition and were also remembered significantly better in literal compared to idiomatic phrases. In Experiment 2, L1 speakers also showed no recall differences between phrase types, but they displayed a trending increase in recognition in the presence of unfamiliar words. We conclude that there is no inherent recognition memory advantage for idioms based on figurativeness alone, and word- and phrasal meaning interact differently in learner groups. (shrink)

Values of some arbitrary parameters appearing in a geometrical model for elementary particles developed by MacGregor are compared with quantities associated with classical properties of blocks of charges±e interacting via Coulomb forces and hard-sphere repulsion only. If it is assumed that masses and radii of individual charged particles are related bymc 2=(2/3)(e 2/r) and thatmc 2=6.87 MeV, then the self-energiesM andM ± of 24-particle neutral blocks and 25-particle charged blocks composed of layers of three octagons and of a square sandwiched (...) by two distorted octagons satisfyM=70.1 MeV,M ±=74.2 MeV. The binding energyB nn of pairs of neutral blocks is given byB nn=4.9 MeV, and the maximum radius of the neutral block is 0.60 F. These four calculated parameter values lie within an average of 1% of the corresponding quantities for nonspinning quarks determined empirically by MacGregor. (shrink)

The term “euthanasia” is used in conflicting ways in the bioethical literature, as is the term “assisted suicide,” resulting in definitional confusion, ambiguities, and biases which are counterproductive to ethical and legal discourse. I aim to rectify this problem in two parts. Firstly, I explore a range of conflicting definitions and identify six disputed definitional factors, based on distinctions between (1) killing versus letting die, (2) fully intended versus partially intended versus merely foreseen deaths, (3) voluntary versus nonvoluntary versus involuntary (...) decisions, (4) terminally ill versus non-terminally ill patients, (5) patients who are fully conscious versus those in permanent comas or persistent vegetative states, and (6) patients who are suffering versus those who are not. Secondly, I distil these factors into six “building blocks” and combine them to develop an unambiguous, value-neutral taxonomy of “end-of-life practices.” I hope that this taxonomy provides much-needed clarification and a solid foundation for future ethical and legal discourse. (shrink)

_A unique philosophical look at the hit television series _Downton Abbey_ _ Who can resist the lure of _Downton Abbey_ and the triumphs and travails of the Crawley family and its servants? We admire Bates's sense of honor, envy Carson's steadfastness, and thrill to Violet's caustic wit. _Downton Abbey and Philosophy_ draws on some of history's most profound philosophical minds to delve deeply into the dilemmas that confront our favorite characters. Was Matthew right to push Mary away after his injury (...) in the war? Would Lord Grantham have been justified in blocking Lady Sybil's marriage to Tom Branson? And is Thomas really such a bad person? Offers fresh and intriguing insights into your favorite _Downton Abbey_ characters, plot lines, and ideas Addresses many of your most pressing questions about _Downton Abbey's_ story and characters, such as: Should Daisy have lied to William about her feelings toward him—especially to the point of marrying him? Should Mr. Bates have been upfront with Anna from the beginning about his past? Views _Downton Abbey_ through the lens of some of the most influential philosophical thinkers, from Saint Augustine and David Hume to Immanuel Kant and John Stuart Mill Ventures upstairs _and_ downstairs to examine key themes involving ethics, virtue, morality, class, feminism, the human condition, and more Philosophical speculation awaits on every page of this essential _Downton Abbey_ companion. So take a seat in your personal library, have the butler pour a cup of tea, and start reading! (shrink)

We present asecond-personalaccount of corporate moral agency. This approach is in contrast to thefirst-personalapproach adopted in much of the existing literature, which concentrates on the corporation’s ability to identify moral reasons for itself. Our account treats relationships and communications as the fundamental building blocks of moral agency. The second-personal account rests on a framework developed by Darwall. Its central requirement is that corporations be capable of recognizing the authority relations that they have with other moral agents. We discuss the relevance (...) of corporate affect, corporate communications, and corporate culture to the second-personal account. The second-personal account yields a new way to specify first-personal criteria for moral agency, and it generates fresh insights into the reasons those criteria matter. In addition, a second-personal analysis implies that moral agency is partly a matter of policy, and it provides a fresh perspective on corporate punishment. (shrink)

The decline in the interest in ethical theory is first outlined, as a background to the author’s discussion of principlism. The author’s own stance, that of a communitarian philosopher, is then described, before the subject of principlism itself is addressed. Two problems stand in the way of the author’s embracing principlism: its individualistic bias and its capacity to block substantive ethical inquiry. The more serious problem the author finds to be its blocking function. Discussing the four scenarios the author (...) finds that the utility of principlism is shown in the two scenarios about Jehovah’s Witnesses but that when it comes to selling kidneys for transplantation and germline enhancement, principlism is of little help. (shrink)

As Professor Rotenstreich indicates "the purpose of the present analysis is to work out in detail Hegel’s attempted reconciliation of substance and subject." Using the major texts of Hegel, Rotenstreich reveals that the subject precedes the various stages of the dialectic rather than coming at the end of the process. Brought into the analysis is the notion of time which is Hegel’s "stumbling block" in reconciling thought and concept with actuality. In addition, the element of history in the philosophy (...) of Hegel is revealed as a shift to speculation embracing religions but the concept of God which in Rotenstreich’s estimation "Hegel willy-nilly imposes a conceptual limit." But Hegel could have gone beyond the ultimate synthesis to render God hyperspeculatively. Underlying the study is an analysis of totality which when interpreted by Kant, Spinoza, Marx and Hegel there are great differences and what seems to emerge is a lack of concept of totality when analyzed in the technological world where the individual and the world are separated in that both are independent and appear to be abstractions. This is an excellent analysis of Hegel and other major thinkers.—G.D.D. (shrink)

A close examination of Kim's argument in "Multiple Realization and the Metaphysics of Reduction" for the claim that if a kind is multiply realizable in a way that blocks identification with more fundamental properties it is also a kind unlikely to appear as an appropriate kind in a theory in the first place. Ultimately, I argue that there is one reasonably promising argument of this sort, but its success turns on explanatory questions the answers to which are far from obvious.

As a comparatively recent development, the adventure-sports coach struggles for a clear and distinct identity. The generic term ‘instructor’ no longer characterizes the role and function of this subgroup of outdoor professionals. Indeed, although the fields of adventure/outdoor education and leadership are comparatively well researched, the arrival of this ‘new kid on the block’ appears to challenge both the adventure-sports old guard and traditional views of sports coaching. In an attempt to offer clarity and stimulate debate, this paper attempts (...) to conceptualize the adventure-sports coach in the context of the existing roles in the field and current motivations for activity in the outdoors. We identify issues that are specific to the adventure-sports coach while also recognizing those skills and competencies shared with other professionals, both in the adventure sports profession and traditional sports coaching fields. Based on this review, we offer a conceptual model which may be used to focus debate, stimulate research and, at a possible later stage, to underpin accreditation, training and professional development. (shrink)

According to ‘composition as identity’, a composite object is identical to all its parts taken together. Thus, a plurality of composite objects is identical to the plurality of those objects’ parts. This has the consequence that, e.g., the bricks which compose a brick wall are identical to the atoms which compose those bricks, and hence that the plurality of bricks must include each of those atoms. This consequence of CAI is in direct conflict with the standard analysis of plural definite (...) descriptions. According to that analysis, the denotation of ‘the bricks’ can include only bricks. It seems, then, that if CAI is true, ‘the bricks’ doesn’t denote anything; more generally, if CAI is true, there are fewer pluralities than we ordinarily think. I respond to this argument by developing an alternative analysis of plural descriptions which allows the denotation of ‘the bricks’ to include non-bricks. Thus, we can accept CAI, while still believing in all the pluralities we could want. As a bonus, my approach to plural descriptions and plural comprehension blocks recent arguments to the effect that CAI entails compositional nihilism. (shrink)

This monograph is a detailed study, and systematic defence, of the Growing Block Theory of time (GBT), first conceived by C.D. Broad. The book offers a coherent, logically perspicuous and ideologically lean formulation of GBT, defends it against the most notorious objections to be found in the extant philosophical literature, and shows how it can be derived from a more general theory, consistent with relativistic spacetime, on the pre-relativistic assumption of an absolute and total temporal order. -/- The authors (...) devise axiomatizations of GBT and its competitors which, against the backdrop of a shared quantified tense logic, significantly improves the prospects of their comparative assessment. Importantly, neither of these axiomatizations involves commitment to properties of presentness, pastness or futurity. The authors proceed to address, and defuse, a number of objections that have been marshaled against GBT, including the so-called epistemic objection according to which the theory invites skepticism about our temporal location. The challenge posed by relativistic physics is met head-on, by replacing claims about temporal variation by claims about variation across spacetime. -/- The book aims to achieve the greatest possible rigor. The background logic is set out in detail, as are the principles governing the notions of precedence and temporal location. The authors likewise devise a novel spacetime logic suited for the articulation, and comparative assessment, of relativistic theories of time. The book comes with three technical appendices which include soundness and completeness proofs for the systems corresponding to GBT and its competitors, in both their pre-relativistic and relativistic forms. -/- The book is primarily directed at researchers and graduate students working on the philosophy of time or temporal logic, but is of interest to metaphysicians and philosophical logicians more generally. (shrink)

The human genome is not a uniform structure but, instead, is a mosaic of bands. Some of these bands can be seen by the eye. Stained with Giemsa and viewed under the microscope each human chromosome has a prototypical pattern of light and dark bands (G and R bands respectively). Other bands are not so easily viewed. The human genome is, for example, a mosaic of isochores, blocks of DNA within which the proportion of the bases G and C at (...) silent sites (introns, third positions in codons, intergene spacer) is fairly uniform. Recent work by Matassi and colleagues(1) has revealed what might be a new and unexpected banding pattern. They have found that the genes which are close together on the chromosome have similar rates of evolution. BioEssays 22:105–107, 2000. ©2000 John Wiley & Sons, Inc. (shrink)