Different types of consent are used to obtain human biospecimens for future research. This variation has resulted in confusion regarding what research is permitted, inadvertent constraints on future research, and research proceeding without consent. The National Institutes of Health Clinical Center's Department of Bioethics held a workshop to consider the ethical acceptability of addressing these concerns by using broad consent for future research on stored biospecimens. Multiple bioethics scholars, who have written on these issues, discussed the reasons for consent, the (...) range of consent strategies, and gaps in our understanding, and concluded with a proposal for broad initial consent coupled with oversight and, when feasible, ongoing provision of information to donors. This article describes areas of agreement and areas that need more research and dialogue. Given recent proposed changes to the Common Rule, and new guidance regarding storing and sharing data and samples, this is an important and tim.. (shrink)

This is a book that no one with a serious interest in the spiritual life can afford to be without.

Emerging from thought-provoking discussions and correspondence Simone Weil had with the Reverend Father Perrin, this classic collection of essays contains her most profound meditations on the relationship of human life to the realm of the transcendant.An enlightening introduction by Leslie Fiedler examines Weil's extraordinary roles as a philosophy teacher turned mystic. "One of the most neglected resources of our century ", Waiting for God will continue to influence spiritual and political thought for centuries to come.

Gravity and Grace was the first ever publication by the remarkable thinker and activist, Simone Weil. In it Gustave Thibon, the priest to whom she had entrusted her notebooks before her untimely death, compiled in one remarkable volume a compendium of her writings that have become a source of spiritual guidance and wisdom for countless individuals.

_Gravity and Grace_ shows Weil's religious thoughts and ideas, drawn from many sources - Christian, Jewish, Indian, Greek and Hindu - and focusing on suffering and redemption. It brings the reader face to face with the profoundest levels of existence as Weil explores the relationship of the human condition to the realm of the transcendent.

Into wrestling with that question, Simone Weil put the very substance of her mind and temperament.

A work first published in English in 1951, _Waiting on God _forms the best possible introduction to the work of Simone Weil, for it brings us into direct contact with this amazing personality, at once so pure, so ardent, so utterly sincere, yet normally so reserved that only her closest friends guessed the secrets of her inner life. The first part of the book concerns her letters written to the Reverend Father Perrin, O.P., who befriended her at Marseilles and, the (...) only priest she knew, became her intimate friend. The second part of the book concerns essays and reflections on such subjects as education, human affliction and the love of God, prayer, and forms of the implicit love of God. (shrink)

"What is required if men and women are to feel at home in society and are to recover their vitality? Into wrestling with that question, Simone Weil put the very substance of her mind and temperament. The apparently solid edifices of our prepossessions fall down before her onslaught like ninepins, and she is as fertile and forthright in her positive suggestions . . . she can be relied upon to toss aside the superficial and to come to grips with the (...) essential and the profound." -- Time Literary Supplement. (shrink)

Introducing the Selected Works of Simone Weil Some of Simone Weil's most important thinking was done through the medium of her notebooks. She used them in several inter-related ways. First, she used them to note things she had read and was researching. Far more often, they were workbooks where she worked through her ideas. Many of the ideas in her completed essays can first be found in her notebooks, and thus the notebooks are invaluable for adding context and nuance along (...) with a sense of development to the reading of those later essays. Finally, her notebooks simply contain Weil's aphoristic writing at its best in its most striking presentation. For that reason alone, the last two notebooks, which she wrote while in New York and London in 1942-43, published in French as "La Connaissance surnaturel" have been read as books of great wisdom. This volume also includes her first notebook from the year 1934, not long after her time in the factory and its subject matter reflects this period in her life. (shrink)

Human behavior depends on the ability to effectively introspect about our performance. For simple perceptual decisions, this introspective or metacognitive ability varies substantially across individuals and is correlated with the structure of focal areas in prefrontal cortex. This raises the possibility that the ability to introspect about different perceptual decisions might be mediated by a common cognitive process. To test this hypothesis, we examined whether inter-individual differences in metacognitive ability were correlated across two different perceptual tasks where individuals made judgments (...) about different and unrelated visual stimulus properties. We found that inter-individual differences were strongly correlated between the two tasks for metacognitive ability but not objective performance. Such stability of an individual’s metacognitive ability across different perceptual tasks indicates a general mechanism supporting metacognition independent of the specific task. (shrink)

Simone Weil (1909-1943) was a defining figure of the twentieth century; a philosopher, Christian, resistance fighter, anarchist, feminist, labor activist and teacher. She was described by T. S. Eliot as "a woman of genius, of a kind of genius akin to that of the saints," and by Albert Camus as "the only great spirit of our time." Originally published posthumously in two volumes, these newly reissued notebooks, are among the very few unedited personal writings of Weil's that still survive today. (...) Containing her thoughts on art, love, science, God and the meaning of life, they give context and meaning to Weil's famous works, revealing a unique philosophy in development and offering a rare private glimpse of her singular personality. (shrink)

_Oppression and Liberty_ is one of Simone Weil's most important books on political theory.Here she discusses political and social oppression, its permanent causes, the way it works and its contemporary forms. Simone Weil's writings on oppression and liberty continue to be as valid and thought-provoking today as they were in her lifetime.

Kerngedachten uit de nagelaten manuscripten van deze jong gestorven schrijfster, doordrongen van een mystiek, die zich richt zowel op de schoonheid van de schepping als op de goddelijke volmaaktheid, en van medeleven met de lijdende mensheid.

A work first published in English in 1951, Waiting on God forms the best possible introduction to the work of Simone Weil, for it brings us into direct contact with this amazing personality, at once so pure, so ardent, so utterly sincere, yet normally so reserved that only her closest friends guessed the secrets of her inner life. The first part of the book concerns her letters written to the Reverend Father Perrin, O.P., who befriended her at Marseilles and, the (...) only priest she knew, became her intimate friend. The second part of the book concerns essays and reflections on such subjects as education, human affliction and the love of God, prayer, and forms of the implicit love of God. (shrink)

In Intimations of Christianity Among the Ancient Greeks , Simone Weil discusses precursors to Christian religious ideas which can be found in ancient Greek mythology, literature and philosophy. She looks at evidence of "Christian" feelings in Greek literature, notably in Electra, Orestes, and Antigone , and in the Iliad , going on to examine God in Plato, and divine love in creation, as seen by the ancient Greeks.

The immediate and guiding aim of this book is to introduce the contemporary reader to the work and thought of Simone Weil.

En 1933-1934, Simone Weil était professeur à Roanne. Dans un petit pavillon isolé au fond d'un parc, sur l'herbe ou sous la neige, elle enseigna alors la philosophie à quelques élèves. On découvrira ici, à travers les notes recueillies par une de ces jeunes filles, ce que furent ces leçons, véritables entretiens socratiques. Le lecteur y reconnaîtra l'unité profonde de Simone Weil dont la vie brève fut intensément consacrée à la recherche de la vérité.

Simone Weil's Leçons de Philosophie are derived from a course she taught at the lyce;e for girls at Roanne in 1933-4. Anne Reynaud-Gue;rithault was a pupil in the class; her notes are not a verbatim record but are a very full and, as far as one can judge, faithful rendering, often catching the unmistakable tone of Simone Weil's voice as well as the force and the directness of her thought. The lectures form a good general introduction to philosophy, ranging widely (...) over problems about perception, mind, language, reasoning and problems in moral and political philosophy too. Her method of presentation is a characteristic combination of abstract argument, personal experience and literary or historical reference. Peter Winch points out in his introduction to the book some of the more systematic connections in her philosophical work (and between this philosophical work and her other concerns), and makes a number of suggestive comparisons between Simone Weil and Wittgenstein. The translation is by Hugh Price from the Plon edition of 1959. Dr Price has added some notes to explain references in the text that might be unfamiliar to English speaking students beginning philosophy. (shrink)

_Oppression and Liberty_ is one of Simone Weil's most important books on political theory.Here she discusses political and social oppression, its permanent causes, the way it works and its contemporary forms. Simone Weil's writings on oppression and liberty continue to be as valid and thought-provoking today as they were in her lifetime.

The Sustained Attention to Response Task is a Go–No-Go signal detection task developed to measure lapses of sustained conscious attention. In this study, we examined the impact global interference and spatial uncertainty has on SART performance. Ten participants performed either a SART or a traditionally formatted version of a global–local stimuli detection task with spatially certain and uncertain signals. Reaction time in the SART was insensitive to global interference and spatial uncertainty, whereas reaction time in the low-Go task was sensitive. (...) Spatial uncertainty increased errors of omission in the SART, which was not expected if the SART measures mindlessness. There was a high correlation between participants’ errors of commission rate and their reaction time in the SART. The results, overall, support the view that the SART is a better measure of response strategy than lapses in sustained attention or mindlessness. (shrink)

To counter confusion about the term ‘mentor’, and address concerns about the scarcity of mentoring, I argue for an “honorific” definition, according to which a mentor is virtuous like a saint or hero. Given the unbounded commitment of mentors, mentoring relationships must be voluntary. In contrast, the role of advisor can be specified, mandated, and monitored. I argue that departments and research groups have a moral responsibility to devise a system of roles and structures to meet graduate students’ and postdoctoral (...) fellows’ needs for information and advice. (shrink)

As Kenneth Pimple points out, scientists’ responsibilities to the larger society have received less attention than ethical issues internal to the practice of science. Yet scientists and specialists who study science have begun to provide analyses of the foundations and scope of scientsts’ responsibilities to society. An account of contributions from Kristen Shrader-Frechette, Melanie Leitner, Ullica Segerstråle, John Ahearne, Helen Longino, and Carl Cranor offers work on scientists’ social responsibilities upon which to build.

Hailed by Albert Camus as ‘the only great spirit of our times’, Simone Weil was one of great essayists and activists of the twentieth century. Her writings on the nature of religious faith and spirituality have inspired many subsequent thinkers. Wrestling with the moral dilemmas entailed by commitment to the Catholic Church, Letter to a Priest is a brilliant meditation on the perennial battle between faith and doubt and resonates today as much as when it was first written. This edition (...) also includes one of her most inspiring and celebrated essays, ‘Human Personality’, where Weil offers a moving and unorthodox account of the preciousness of human beings. With a new foreword by Raimond Gaita. (shrink)

Introduction Simone Weil experienced the uprootedness of the twentieth century early and continuously. She was born in Paris in 1909, the second child of ...