Le débat sur l’existence réelle du point a occupé une place importante dans les débats philosophiques parisiens du deuxième quart du xive siècle. La contribution de Jean Buridan à ce débat est bien connue mais à ce jour, l’identité d’un certain « magister M. de Montescalerio », adversaire réaliste de Buridan et auteur d’une Determinatio de puncto, est restée inconnue. Cet article établit l’identité de cet important maître actif vers 1340 à la faculté des arts de Paris et en retrace (...) la carrière. (shrink)

What kind of society do we live in? What kind of politics can help us to live in a good society? The first of these questions is essential to theory of society, the second to political theory. The contributions in this volume investigate the relationship between these two questions and, thus, open new perspectives for assessing politics and the society. The opposing terms "renewal" and "disenchantment" are herein used as leading ideas by which political theory could provide impulses to theory (...) of society. (shrink)

This handbook provides an overview of key ideas, questions, and puzzles in political epistemology. It is divided into seven sections: (1) Politics and Truth: Historical and Contemporary Perspectives; (2) Political Disagreement and Polarization; (3) Fake News, Propaganda, Misinformation; (4) Ignorance and Irrationality in Politics; (5) Epistemic Virtues and Vices in Politics; (6) Democracy and Epistemology; (7) Trust, Expertise, and Doubt.

An intuitive and widely accepted view is that (a) beliefs aim at truth, (b) many citizens have stable and meaningful political beliefs, and (c) citizens choose to support political candidates or parties on the basis of their political beliefs. We argue that all three claims are false. First, we argue that political beliefs often differ from ordinary world-modelling beliefs because they do not aim at truth. Second, we draw on empirical evidence from political science and psychology to argue that most (...) people lack stable and meaningful political beliefs. Third, we claim that the true psychological basis for voting behavior is not an individual’s political beliefs but rather group identity. Along the way, we reflect on what this means for normative democratic theory. (shrink)

The desire for a meaningful life is ubiquitous, yet the ordinary concept of a meaningful life is poorly understood. Across six experiments (total N = 2,539), we investigated whether third-person attributions of meaning depend on the psychological states an agent experiences (feelings of interest, engagement, and fulfillment), or on the objective conditions of their life (e.g., their effects on others). Studies 1a–b found that laypeople think subjective and objective factors contribute independently to the meaningfulness of a person’s life. Studies 2a–b (...) found that positive mental states are thought to make a life more meaningful, even if derived from senseless activities (e.g., hand-copying the dictionary). Studies 3a–b found that agents engaged in morally bad activities are not thought to have meaningful lives, even if they feel fulfilled. In short, both an agents’ subjective mental states and objective impact on the world affect how meaningful their lives appear. (shrink)

This article sets out to describe how churches have responded and continue to respond to fast-changing urban environments in Pretoria Central and Mamelodi East, animating Henri Lefebvre’s sociological perspective of citadins or urban inhabitants. We make tentative interpretations and offer critical appreciation. Churches, which were historically separated from the city centre, now directly participate in claiming a right to the city. With necessary fluidity, churches express lived African urbanisms through informality, place-making, spatial innovation and everyday rituals. Though not exhaustive, the (...) article focuses on rituals shared among historic urban Christians and contemporary African urban Christians, namely prayer, listening to the Bible and worship. These rituals, when combined with the churches’ spatial innovation, to a certain degree contribute to place-making. (shrink)

The employment application form is a major source of information about candidates for many companies. It is also a potential source of infringement by the company upon the privacy of the individual. Although September 1984 saw the passing into law of the Data Protection Act, the U.K. has not been in the forefront of civil rights where employees and personal information are concerned. During an extended interview with members of a personnel department of a major company, several issues relating to (...) privacy issues were revealed and these are discussed in the paper. Although these interviews were carried out before the new law came into effect, they do show that this and many similar organisations may experience problems over compliance. This is particularly likely in the computerisation of personnel records and employees' access to their personal information. (shrink)

We examine whether Thomsonian constitutivism, a metaethical view that analyses value in terms of ‘goodness-fixing kinds,’ i.e. kinds that themselves set the standards for being a good instance of the respective kind, offers a satisfactory explanation of value change and disagreement. While value disagreement has long been considered an important explanandum, we introduce value change as a closely related but distinct phenomenon of metaethical interest. We argue that constitutivism fails to explain both phenomena because of its commitment to goodness-fixing kinds. (...) Constitutivism explains away disagreement and at best explains the emergence of new values, not genuine change. Therefore, Thomsonian constitutivism is not a good fix for realist problems with explaining value disagreement, and value change. (shrink)

Eric G. Forbes, Lesley Murdin and Francis Willmoth , The Correspondence of John Flamsteed, First Astronomer Royal. Volume 1: 1666–1682. Bristol and Philadelphia: Institute of Physics Publishing, 1995. Pp. xlix+955. ISBN 0-7503-0147-3. £140.00, $280.00.Heinz-Jurgen Hess, James G. O'Hara and Herbert Breger , Gottfried Wilhelm Leibniz: Sämtliche Schriften und Briefe. Dritte Reihe, Mathematischer, naturwissenschaftlicher und technischer Briefwechsel: Volume 3, 1680–1683; Volume 4, 1683–1690. Berlin: Akademie Verlag, 1991, 1995. Pp. lxx+895; lxvi+747. ISBN 3-05-000766-4, DM 490.00 ; 3-05-002602-2, DM 490.00 .Wilhelm Schmidt-Biggemann , (...) Samuel Pufendorf. Gesammelte Werke, Band 1: Briefwechsel . Berlin: Akademie Verlag, 1996. Pp. xxix+453. ISBN 3-05-001920-4. DM 298.00.The editing of the correspondence of major figures in intellectual history is an essential scholarly activity. Yet in this country in recent years it has neither been the priority it should be, nor has it received the support that it deserves. Of course there have been exceptions to this, perhaps notably – for the early modern period – the epic one-man effort of Esmond de Beer in his later years in producing The Correspondence of John Locke . A further exception, the edition of The Correspondence of Henry Oldenburg by A. R. and M. B. Hall, was unfortunately flawed by the need to change publishers midway in the series, which has led to a marked disparity in the availability of the latter part of the set compared with its early volumes. In any case, like the Locke edition, this was conceived in the heady days of the 1960s and early 1970s, and few have ventured such enterprises since. Virtually the only exception is Noel Malcolm's edition of the manageable-sized Correspondence of Thomas Hobbes . Moreover, it is revealing of the acute need to justify the publication of such material felt by editors and publishers alike that the promotional leaflet for this edition went so far as to claim that it was ‘one of the most important scholarly publications of the twentieth century’ – a claim that is the more ironic in view of the quite significant shortcomings in its method of presenting the material that it contains. (shrink)

Deep learning and other black-box models are becoming more and more popular today. Despite their high performance, they may not be accepted ethically or legally because of their lack of explainability. This paper presents the increasing number of legal requirements on machine learning model interpretability and explainability in the context of private and public decision making. It then explains how those legal requirements can be implemented into machine-learning models and concludes with a call for more inter-disciplinary research on explainability.

In this article we defend a moral conception of cosmopolitanism and its relevance for moral education. Our moral conception of cosmopolitanism presumes that persons possess an inherent dignity in the Kantian sense and therefore they should be recognised as ends‐in‐themselves. We argue that cosmopolitan ideals can inspire moral educators to awaken and cultivate in their pupils an orientation and inclination to struggle against injustice. Moral cosmopolitanism, in other words, should more explicitly inform the work that moral educators do. Real‐world constraints (...) on moral action and the need to prioritise one’s sometimes conflicting responsibilities will often qualify cosmopolitan justice as supererogatory. This fact does not absolve persons from aspiring to see themselves as having the moral obligation to help others in need, while recognising that their factual obligations are more modest in being bound by what they are actually able to do. (shrink)

ABSTRACT Previous research has consistently highlighted the importance of stakeholder engagement in identifying and developing solutions to ethical challenges in genomic research, especially in Africa where such research is relatively new. In this paper, we examine what constitutes good ethical practice in research, from the perspectives of genomic research participants in Uganda. Our study was part of a multi-site qualitative study exploring these issues in Uganda, Ghana and Zambia. We purposively sampled various stakeholders including genomic research participants, researchers, research ethics (...) committee members, policy makers and community members. This paper presents the findings from in-depth interviews with 27 people with diabetes who had participated in a diabetes genomic study. Data were collected using semi-structured interviews. Manual thematic content analysis was conducted using a framework approach. Findings indicate three key requirements that research participants see as vital for genomic research to be more responsive to research participants’ needs and contextual realities: (1) de-emphasising the role of experts and institutions in the consenting process, (2) clarity about the timing and nature of feedback both of findings relevant to the health of individuals and about the broad progress of the study, and (3) more effective support for research participants during and after the study. (shrink)

This paper begins by exploring the anti-colonial work of Tunisian scholar Albert Memmi in his classic book The Colonizer and the Colonized and determining whether the characteristics of colonization that he names can be successfully applied to the current relationship between modern humans and the “natural world”. After considering what we found to be the five key characteristics: manufacturing the colonial, alienation and unknowability, violence, psychological strategies (bad faith), and language, history, and metaphor we draw clear parallels, through selected examples, (...) to the exploitative relationships enacted in many realms of the modern human/nature relationship. In so doing the paper posits that the beings that comprise the “natural world” are colonized. It then continues from that position to explore the possibility of cultivating practices of listening to the voices of these colonized others to inform anti-colonial ecopedagogy as allies. We employ the term “shut-up” as an anti-colonial gesture to remind ourselves as much as others of the importance of first listening to the colonized other before engaging in “post-colonial” theorizing about prospective relationships or liberatory solutions “for” them. Given the fast-paced and cacophonic urban life many humans increasingly inhabit, and the disciplined and reiterative practice(s) required to learn to listen to other voices, we suggest caution and care when importing postcolonial theory into “environmental” contexts and seek to instigate further discussion as to how we might enact solidarity with other beings as anti-colonial allies in education. To this end, we conclude the paper with some educational implications based on research at a place-based school and focus on the role history, language and metaphor play in manufacturing a colonial relationship, but also provide a potential means for changing relationships with the diverse beings with whom we share the planet. (shrink)

IntroductionIn highly developed countries, as many as 16 percent of children are physically abused each year. Traumatic brain injury (TBI) is the most common injury in non-accidental trauma (NAT) and is responsible for 80 percent of fatal NAT cases, with most deaths occurring in children younger than three years old. Cases of abusers who refuse withdrawal of life-sustaining medical treatment (LSMT) to avoid criminal charges have previously been reported. Therefore, we hypothesized that NAT is associated with a lower risk for (...) withdrawal LSMT in pediatric TBI.MethodsThe pediatric Trauma Quality Improvement Program database was analyzed (2014 to 2016) for patients aged 16 and younger with TBI and Glasgow Coma Scale (GCS) of 8 and lower on admission. Patients with a head Abbreviated Injury Scale (AIS) of 2 or less or who died within 48 hours were excluded. A multivariable logistic regression model was used for analysis.ResultsOf 2,209 TBI patients, 92 (4.2 percent) had withdrawal of LSMT. Compared to those without withdrawal of LMST, those with LMST had statistically similar median age (three years of age versus seven years, p = 0.07) and a higher rate of NAT (33.7 percent versus 13.5 percent, p < 0.001). The most common specified perpetrator was a father/stepfather/ male partner (70 percent). After adjusting for covariates, factors associated with higher risk for withdrawal of LSMT included age of less than three years (OR 2.38, CI 1.34-4.23, p < 0.05) and NAT (OR 1.86, CI 1.02-3.41, p < 0.05).ConclusionNAT is associated with increased risk for withdrawal of LSMT in pediatric TBI. Age of less than three years is similarly associated with a higher risk for withdrawal of LSMT. Future research in this population is needed to determine what other factors predict withdrawal of LSMT and what resources, such as social workers and/or ethics consults, are utilized. (shrink)

A simple numerical procedure is presented for the problem of estimating the parameters of models for the distribution of eggs oviposited in a host. The modelling is extended to incorporate both host density and time dependence to produce a remarkably parsimonious structure with only seven parameters to describe a data set of over 3,000 observations. This is further refined using a mixed model to accommodate several large outliers. Both models show that the level of superparasitism declines with increasing host density, (...) and the rate declines over time. It is proposed that the differing behaviours represented by the mixed model may reflect a balance between behavioural strategies of different selective benefit. (shrink)

After 50 years of materialist culture, people are desperately seeking answers to such questions as the proper sharing of the bounty of the planet and also the human economy. Who should have and who should have not and can inequality ever be justified. Should humans take every last benefit from the planet or do we need other species and do we need to learn to share and to respect nature. We are not alone on this planet but we might be (...) a very short lived species if we dont get a grip on our proper role. This unique book brings texts and discussion from some of the founders of the green movement and makes todays' philosophy accessible and usable for everyone! The main features of philosophical possibilities for the 21st century and brings the light of Green Movement thinking to bear on todays issues. The Green Movements' original philosophical questions and conundrums in the light of todays' challenges. Shinning a very modern light on Classical texts This book introduces the philosophical basis and understanding of the Green Movements' amazingly accurate predictions on climate and global environmental physical and political change to a broader group of readers, students, policy makers, academics and campaigners in this ground breaking volume. (shrink)

We develop a framework for assessing security market quality, relating five elements of market design to three metrics of market integrity and two metrics of market efficiency. We empirically implement this integrity–efficiency MQ framework by testing a hypothesis that trade-based ramping manipulation at the close raises execution costs on 24 security markets worldwide. Estimating a simultaneous equations model of ramping incidence, spreads, and the probability of deploying real-time surveillance, we show that quoted bid-ask spreads are positively related to the incidence (...) of MTC across seven liquidity deciles. The magnitude is economically significant; improving market integrity by cutting MTC in half reduces spreads 6–11 %. Allowing direct market access in conjunction with RTS, conducting auctions at the close, and developing regulations that require surveillance, all reduce MTC and thereby lower spreads, assuring better market integrity and enhancing market efficiency. Introducing circuit breakers or prohibiting shorts poses integrity–efficiency tradeoffs. (shrink)

According to the simple modal account of essence, an object has a property essentially just in case it has it in every world in which it exists. As many have observed, the simple modal account is implausible for a number of reasons. This has led to various proposals for strengthening the account, for example, by adding a restriction to the intrinsic or sparse properties. I argue, however, that these amendments to the simple modal account themselves fail. Drawing on lessons from (...) these failures, I propose a new version of a modal account, inspired by Ruth Barcan Marcus's defense of the coherence of quantified modal logic, according to which an object has a property essentially just in case (i) it has it in every world in which it exists, (ii) the property is discriminating (or non-trivial), and (iii) the property is qualitative. The resulting account of essence does not face any of the standard objections other accounts face, and I defend it from other potential objections. (shrink)

Both fairness and efficiency are important considerations in market design and regulation, yet many regulators have neither defined nor measured these concepts. We develop an evidencebased policy framework in which these are both defined and measured using a series of empirical proxies. We then build a systems estimation model to examine the 2003–2011 explosive growth in algorithmic trading on the London Stock Exchange and NYSE Euronext Paris. Our results show that greater AT is associated with increased transactional efficiency and reduced (...) information leakage in top quintile stocks. For less liquid stocks, manipulation at the close declines. We also document the tradeoff between reduced spreads and increased manipulation or information leakage following the introduction of MiFID1. (shrink)

Both fairness and efficiency are important considerations in market design and regulation, yet many regulators have neither defined nor measured these concepts. We develop an evidencebased policy framework in which these are both defined and measured using a series of empirical proxies. We then build a systems estimation model to examine the 2003–2011 explosive growth in algorithmic trading on the London Stock Exchange and NYSE Euronext Paris. Our results show that greater AT is associated with increased transactional efficiency and reduced (...) information leakage in top quintile stocks. For less liquid stocks, manipulation at the close declines. We also document the tradeoff between reduced spreads and increased manipulation or information leakage following the introduction of MiFID1. (shrink)

We investigate the notion of classical negation from a non-classical perspective. In particular, one aim is to determine what classical negation amounts to in a paracomplete and paraconsistent four-valued setting. We first give a general semantic characterization of classical negation and then consider an axiomatic expansion BD+ of four-valued Belnap–Dunn logic by classical negation. We show the expansion complete and maximal. Finally, we compare BD+ to some related systems found in the literature, specifically a four-valued modal logic of Béziau and (...) the logic of classical implication and a paraconsistent de Morgan negation of Zaitsev. (shrink)

BackgroundGenome-wide association studies (GWAS) provide a powerful means of identifying genetic variants that play a role in common diseases. Such studies present important ethical challenges. An increasing number of GWAS is taking place in lower income countries and there is a pressing need to identify the particular ethical challenges arising in such contexts. In this paper, we draw upon the experiences of the MalariaGEN Consortium to identify specific ethical issues raised by such research in Africa, Asia and Oceania.DiscussionWe explore ethical (...) issues in three key areas: protecting the interests of research participants, regulation of international collaborative genomics research and protecting the interests of scientists in low income countries. With regard to participants, important challenges are raised about community consultation and consent. Genomics research raises ethical and governance issues about sample export and ownership, about the use of archived samples and about the complexity of reviewing such large international projects. In the context of protecting the interests of researchers in low income countries, we discuss aspects of data sharing and capacity building that need to be considered for sustainable and mutually beneficial collaborations.SummaryMany ethical issues are raised when genomics research is conducted on populations that are characterised by lower average income and literacy levels, such as the populations included in MalariaGEN. It is important that such issues are appropriately addressed in such research. Our experience suggests that the ethical issues in genomics research can best be identified, analysed and addressed where ethics is embedded in the design and implementation of such research projects. (shrink)

Modal Logic, originally conceived as the logic of necessity and possibility, has developed into a powerful mathematical and computational discipline. It is the main source of formal languages aimed at analyzing complex notions such as common knowledge and formal provability. Modal and modal-like languages also provide us with families of restricted description languages for relational and topological structures; they are being used in many disciplines, ranging from artificial intelligence, computer science and mathematics via natural language syntax and semantics to philosophy. (...) This volume presents a broad and up-to-date view of the field, with contributions covering both the foundations of modal logic itself and each of the aforementioned application areas. Complemented with an editorial introduction covering the roots of modal logic, this book is indispensable for any advanced student and researcher in non-classical logic and its applications. (shrink)

There is a relatively recent trend in treating negation as a modal operator. One such reason is that doing so provides a uniform semantics for the negations of a wide variety of logics and arguably speaks to a longstanding challenge of Quine put to non-classical logics. One might be tempted to draw the conclusion that negation is a modal operator, a claim Francesco Berto, 761–793, 2015) defends at length in a recent paper. According to one such modal account, the negation (...) of a sentence is true at a world x just in case all the worlds at which the sentence is true are incompatible with x. Incompatibility is taken to be the key notion in the account, and what minimal properties a negation has comes down to which minimal conditions incompatibility satisfies. Our aims in this paper are twofold. First, we wish to point out problems for the modal account that make us question its tenability on a fundamental level. Second, in its place we propose an alternative, non-modal, account of negation as a contradictory-forming operator that we argue is superior to, and more natural than, the modal account. (shrink)

This theoretical analysis seeks to contribute to three objectives within the context of the proposed Frontiers Research Topic: delimit two levels of analysis in the present pandemic situation: medicine-epidemiology and behavioral psychology, still under-addressed. While medicine has its essential role on the biological side, psychology has a comparable role on the behavioral side. Analyze the importance of behavioral-educational factors in the pandemic situation, using a precise theoretical model from educational psychology for this analysis. Propose preventive, psychoeducational intervention strategies based on (...) the previous analyses. (shrink)

In this paper, we introduce the Societal Readiness Thinking Tool to aid researchers and innovators in developing research projects with greater responsiveness to societal values, needs, and expectations. The need for societally-focused approaches to research and innovation—complementary to Technology Readiness frameworks—is presented. Insights from responsible research and innovation concepts and practice, organized across critical stages of project-life cycles are discussed with reference to the development of the SR Thinking Tool. The tool is designed to complement not only shortfalls in TR (...) approaches, but also improve upon other efforts to integrate RRI, sustainability, and design thinking in research and innovation cycles. Operationalization and early-stage user tests of the Tool are reported, along with discussion of potential future iterations and applications. (shrink)

This paper begins by exploring the anti-colonial work of Tunisian scholar Albert Memmi in his classic book The Colonizer and the Colonized and determining whether the characteristics of colonization that he names can be successfully applied to the current relationship between modern humans and the “natural world”. After considering what we found to be the five key characteristics: manufacturing the colonial, alienation and unknowability, violence, psychological strategies, and language, history, and metaphor we draw clear parallels, through selected examples, to the (...) exploitative relationships enacted in many realms of the modern human/nature relationship. In so doing the paper posits that the beings that comprise the “natural world” are colonized. It then continues from that position to explore the possibility of cultivating practices of listening to the voices of these colonized others to inform anti-colonial ecopedagogy as allies. We employ the term “shut-up” as an anti-colonial gesture to remind ourselves as much as others of the importance of first listening to the colonized other before engaging in “post-colonial” theorizing about prospective relationships or liberatory solutions “for” them. Given the fast-paced and cacophonic urban life many humans increasingly inhabit, and the disciplined and reiterative practice required to learn to listen to other voices, we suggest caution and care when importing postcolonial theory into “environmental” contexts and seek to instigate further discussion as to how we might enact solidarity with other beings as anti-colonial allies in education. To this end, we conclude the paper with some educational implications based on research at a place-based school and focus on the role history, language and metaphor play in manufacturing a colonial relationship, but also provide a potential means for changing relationships with the diverse beings with whom we share the planet. (shrink)

An extension of intuitionism to empirical discourse, a project most seriously taken up by Dummett and Tennant, requires an empirical negation whose strength lies somewhere between classical negation (‘It is unwarranted that. . . ’) and intuitionistic negation (‘It is refutable that. . . ’). I put forward one plausible candidate that compares favorably to some others that have been propounded in the literature. A tableau calculus is presented and shown to be strongly complete.

An intuitive objection to modal realism is that merely possible worlds and their inhabitants seem to be irrelevant to an analysis of modality. Kripke originally phrased the objection in terms of being concerned about one’s modal properties without being concerned about the properties one’s other-worldly counterparts have. The author assesses this objection in a variety of forms, and then provides his own formulation that does not beg the question against the modal realist. Finally, the author considers two potential answers to (...) the objection so understood and concludes that only one of them has a chance of succeeding. (shrink)

It is shown that counterpart theory and the duplication account of intrinsicality —two key pieces of the Lewisian package—are incompatible. In particular, the duplication account yields the result that certain intuitively extrinsic modal properties are intrinsic. Along the way I consider a potentially more general worry concerning certain existential closures of internal relations. One conclusion is that, unless the Lewisian provides an adequate alternative to the duplication account, the reductive nature of their total theory is in jeopardy.

People’s beliefs about their ability to control their emotions predict a range of important psychological outcomes. It is not clear, however, whether these beliefs are playing a causal role, and if so, why this might be. In the current research, we tested whether avoidance-based emotion regulation explains the link between beliefs and psychological outcomes. In Study 1, a perceived lack of control over emotions predicted poorer psychological health outcomes, and avoidance strategies indirectly explained these links between emotion beliefs and psychological (...) health. In Study 2, we experimentally manipulated participants’ emotion beliefs by leading participants to believe that they struggled or did not struggle with controlling their emotions. Participants in the low regulatory self-efficacy condition reported increased intentions to engage in avoidance strategies over the next month and were more likely to avoid seeking psychological help. When asked if they would participate in follow-up studies, these participants were also more likely to display avoidance-based emotion regulation. These findings provide initial evidence for the causal role of emotion beliefs in avoidance-based emotion regulation, and document their impact on psychological health-related outcomes. (shrink)

The aim of the study is to encourage a critical debate on the use of normality in the medical literature on DSD or intersex. For this purpose, a scoping review was conducted to identify and map the various ways in which “normal” is used in the medical literature on DSD between 2016 and 2020. We identified 75 studies, many of which were case studies highlighting rare cases of DSD, others, mainly retrospective observational studies, focused on improving diagnosis or treatment. The (...) most common use of the adjective normal was in association with phenotypic sex. Overall, appearance was the most commonly cited criteria to evaluate the normality of sex organs. More than 1/3 of the studies included also medical photographs of sex organs. This persistent use of normality in reference to phenotypic sex is worrisome given the long-term medicalization of intersex bodies in the name of a “normal” appearance or leading a “normal” life. Healthcare professionals should be more careful about the ethical implications of using photographs in publications given that many intersex persons describe their experience with medical photography as dehumanizing. (shrink)

In this article we aim to open a new line of debate about religion in public schools by focusing on religious ideals. We begin with an elucidation of the concept ‘religious ideals’ and an explanation of the notion of reasonable pluralism, in order to be able to explore the dangers and positive contributions of religious ideals and their pursuit on a liberal democratic society. We draw our examples of religious ideals from Christianity and Islam, because these religions have most adherents (...) in Western liberal democracies that are the focus of this article. The fifth and most important section ‘‘Reasonable pluralism and the inclusion of religious ideals in public secondary schools’’ provides three arguments for our claim that public schools should include religious ideals, namely that they are important to religious people, that they are conducive for the development of pupils into citizens of a liberal democracy, and that the flourishing of pupils as adults is advanced by encountering religious ideals. We also offer a more practical reason: religious ideals can more easily be included within public education than religious dogmas and rules. (shrink)

Scientific interest in genomics in Africa is on the rise with a number of funding initiatives aimed specifically at supporting research in this area. Genomics research on material of African origin raises a number of important ethical issues. A prominent concern relates to sample export, which is increasingly seen by researchers and ethics committees across the continent as being problematic. The concept of genomic sovereignty proposes that unique patterns of genomic variation can be found in human populations, and that these (...) are commercially, scientifically or symbolically valuable and in need of protection against exploitation. Although it is appealing as a response to increasing concerns regarding sample export, there are a number of important conceptual problems relating to the term. It is not clear, for instance, whether it is appropriate that ownership over human genomic samples should rest with national governments. Furthermore, ethnic groups in Africa are frequently spread across multiple nation states, and protection offered in one state may not prevent researchers from accessing the same group elsewhere. Lastly, scientific evidence suggests that the assumption that genomic data is unique for population groups is false. Although the frequency with which particular variants are found can differ between groups, such genes or variants per se are not unique to any population group. In this paper, the authors describe these concerns in detail and argue that the concept of genomic sovereignty alone may not be adequate to protect the genetic resources of people of African descent. (shrink)

ABSTRACT The use of broad consent for genomics research raises important ethical questions for the conduct of genomics research, including relating to its acceptability to research participants and comprehension of difficult scientific concepts. To explore these and other challenges, we conducted a study using qualitative methods with participants enrolled in an H3Africa Rheumatic Heart Disease genomics study (the RHDGen network) in Zambia to explore their views on broad consent, sample and data sharing and secondary use. In-depth interviews were conducted with (...) RHDGen participants (n = 18), study staff (n = 5) and with individuals who refused to participate (n = 3). In general, broad consent was seen to be reasonable if reasons for storing the samples for future research use were disclosed. Some felt that broad consent should be restricted by specifying planned future studies and that secondary research should ideally relate to original disease for which samples were collected. A few participants felt that broad consent would delay the return of research results to participants. This study echoes findings in other similar studies in other parts of the continent that suggested that broad consent could be an acceptable consent model in Africa if careful thought is given to restrictions on re-use. (shrink)