With the advent of CRISPR gene-editing technology, designer babies have become a reality. Françoise Baylis insists that scientists alone cannot decide the terms of this new era in human evolution. Members of the public, with diverse interests and perspectives, must have a role in determining our future as a species.

In this paper, I begin to construct an inheritance map for the epistemological insights in Patricia Hill Collins’s book Black Feminist Thought. An inheritance map attempts to take stock of what one has been given in a particular project and what one inherits as work yet to do. Here I outline that Black Feminist Thought demonstrates that knowledge has no proper subject, while leaving a project to imagine black feminist epistemology outside of ascriber dynamics.

Discussion of a metaphysical sense of 'inheritance' and cognate notions relevant to fundamentality.

Inheriting Benjamin otherwise -- Erbsünde: a note on paradoxical inheritance in Benjamin's Kafka essay -- Benjamin's blotting paper: writing and erasing a theological figure of thought -- Critique and the thing: Benjamin and Heidegger -- The work of art and its formal and genealogical determinations: Benjamin's cool place between Kant and Nietzsche -- Going with time: a miniature on time and photography after Benjamin.

Niche construction theory (NCT) is distinctive for being explicit in recognizing environmental modification by organisms—niche construction—and its legacy—ecological inheritance—to be evolutionary processes in their own right. Humans are widely regarded as champion niche constructors, largely as a direct result of our capacity for the cultural transmission of knowledge and its expression in human behavior, engineering, and technology. This raises the question of how human ecological inheritance relates to human cultural inheritance. If NCT is to provide a conceptual (...) framework for the human sciences, then it is important that the relationship between these two legacies is clear. We suggest that cultural processes and cultural inheritance can be viewed as the primary means by which humans engage in the universal process of niche construction. (shrink)

In most cultures, extramarital sex is highly restricted for women. In most of those cultures, men transfer wealth to their own sons. In some cultures extramarital sex is not highly restricted for women, and in most of those cultures, men transfer wealth to their sisters' sons. Inheritance to sisters' sons ensures a man's biological relatedness to his heirs, and matrilineal inheritance has been posited as a male accommodation to cuckoldry—a paternity strategy—at least since the 15th century. However, longitudinal (...) analysis of the cumulative effect of female extramarital sex indicates that matrilineal inheritance is most advantageous for women and would be more accurately considered a grandmaternity strategy. That is, if the probability that men's putative children are their biological children is less than 1, the probabilistic degree of relatedness between a female and her matrilineal heirs is higher than her corresponding relatedness to her patrilineal heirs. The same holds true for men only if ρ is very low. The upshot is that for moderate levels of female extramarital sex, matrilineal inheritance, relative to patrilineal inheritance, is highly advantageous for women and disadvantageous for men. Consideration of female variance in reproductive success beyond the first generation, and of a man's network of obligation to the inclusive fitness of his relatives, suggests that although the establishment of matrilineal inheritance may require extremely high levels of female extramarital sex, once established, it is likely to be maintained at levels of ρ that reasonably characterize many societies in the ethnographic record. New analysis of previously published data shows a strong association between matrilineal inheritance and moderate to low probability of paternity, and an even stronger relationship between patrilineal inheritance and high probability of paternity. (shrink)

Recent theoretical work has identified a tightly-constrained sense in which genes carry representational content. Representational properties of the genome are founded in the transmission of DNA over phylogenetic time and its role in natural selection. However, genetic representation is not just relevant to questions of selection and evolution. This paper goes beyond existing treatments and argues for the heterodox view that information generated by a process of selection over phylogenetic time can be read in ontogenetic time, in the course of (...) individual development. Recent results in evolutionary biology, drawn both from modelling work, and from experimental and observational data, support a role for genetic representation in explaining individual ontogeny: both genetic representations and environmental information are read by the mechanisms of development, in an individual, so as to lead to adaptive phenotypes. Furthermore, in some cases there appears to have been selection between individuals that rely to different degrees on the two sources of information. Thus, the theory of representation in inheritance systems like the genome is much more than just a coherent reconstruction of information talk in biology. Genetic representation is a property with considerable explanatory utility. (shrink)

'...a challenging and useful book, both because it provokes a careful scrutiny of one's own basic ideas regarding evolutionary theory, and because it cuts across so many biological disciplines.' -The Quarterly Review of Biology 'In my view, this work exemplifies Theoretical Biology at its best...here is rampant speculation that is consistently based on cautious reasoning from the available data. Even more refreshing is the absence of sloganeering, grandstanding, and 'isms'.' -Biology and Philosophy 'Epigenetics is fundamental to understanding both development and (...) gene expression, and not surprisingly, evolutionary biologists have long been fascinated with its proper place in evolutionary theory...Enter Jablonka and Lamb, who provide a thoughtful review of the recent molecular literature and suggest a number of potential consequences.' -EvolutionSince first publication of this controversial book, much of the initial opposition to the ideas it contained has been replaced by a general, although often grudging, acceptance of them. Advances in knowledge, especially at the molecular level, have enhanced general awareness and interest in epigenetics and the evolution of systems that store and transmit information and put any of the authors' speculations on a more solid basis. This paperback edition contains a new Preface that sets out the major changes in the scientific world and in the authors' own thinking that have occurred since the book was published. A new Appendix provides a selected bibliography of the many books and articles about epigenetic inheritance and its role in evolution that have appeared since first publication. (shrink)

Inheritance is the principle that deontic `ought' is closed under entailment. This paper is about a tension that arises in connection with Inheritance. More specifically, it is about two observations that pull in opposite directions. One of them raises questions about the validity of Inheritance, while the other appears to provide strong support for it. We argue that existing approaches to deontic modals fail to provide us with an adequate resolution of this tension. In response, we develop (...) a positive analysis, and show that this proposal provides a satisfying account of our intuitions. (shrink)

Since the discovery of the double helical structure of DNA, the standard account of the inheritance of features has been in terms of DNA-copying and DNA-transmission. This theory is just a version of the old theory according to which the inheritance of features is explained by the transfer at conception of some developmentally privileged material from parents to offspring. This paper does the following things: (1) it explains what the inheritance of features is; (2) it explains how (...) the DNA-centric theory emerged; (3) it clarifies the relation between the DNA-centric theory and the ‘unfolding’ theory of development; (4) it argues that (given what we now know about developmental processes and genetic activity) the DNA-centric theory should be abandoned in favour of a pluralistic (but not holistic) theory of the inheritance of features. According to this pluralistic theory, the reliable reoccurrence of phenotypes must be explained by appealing not only to processes responsible for the reliable reoccurrence of genetic developmental factors but also to processes responsible for the reliable reoccurrence (or persistence) of nongenetic developmental factors. (shrink)

Organisms inherit various kinds of developmental information and cues from their parents. The study of inheritance systems is aimed at identifying and classifying the various mechanisms and processes of heredity, the types of hereditary information that is passed on by each, the functional interaction between the different systems, and the evolutionary consequences of these properties. We present the discussion of inheritance systems in the context of several debates. First, between proponents of monism about heredity (gene-centric views), holism about (...) heredity (Developmental Systems Theory), and those stressing the role of multiple systems of inheritance. Second, between those analyzing inheritance solely in terms of replication and transmission, and views that stress the multi-generation reproduction of phenotypic traits. A third debate is concerned with different criteria that have been proposed for identifying and delimiting inheritance systems. A fourth controversy revolves around the significance of the “Lamarckian” aspects of some of the inheritance systems that have been identified, such as epigenetic inheritance and behavioral inheritance, that allow the transmission of environmentally induced characters (i.e., “soft inheritance”). (shrink)

The paper outlines the contours of an organizational perspective on extended inheritance. Based on theoretical studies about biological organization and extended physiology, this perspective allows for the conception of extended biological legacies while keeping a theoretically indispensable distinction between biological systems and their environment. In this context, the line of demarcation between these systems and their surroundings is modelled on an organizational criterion and on the related conceptual distinction between organizational constraints, whose specific role is to harness flows of (...) matter and energy across generations of composite biological systems, and resources exploited by those systems. Biological legacies are restricted to persisting constitutive elements responsible for the reoccurrence of organizational constraints in a given environment. The case of symbiotic transmission is presented as a paradigmatic system illustrating the main proposed conceptual clarifications. (shrink)

Daniel Halliday examines the morality of the right to bequeath or transfer wealth, and argues that inheritance is unjust to the extent that it enhances the intergenerational replication of inequality, concentrating opportunities in certain groups. He presents an egalitarian case for imposition of a significant inheritance tax.

This article addresses the question of whether present day individuals can inherit rights to compensation from their ancestors. It argues that contemporary writing on compensatory justice in general, and on the inheritability of rights to compensation in particular, has mischaracterized what is at stake in contexts where those responsible for wrongdoing continually refuse to make reparation for their unjust actions, and has subsequently misunderstood how later generations can advance claims rooted in the past mistreatment of their forebears. In particular, a (...) full consideration of the wrongful character of non-rectification needs to take account of the multiplicity of temporal points at which compensation could have been, but was not, paid, each with potentially significant consequences for the victims of injustice. This has relevance for what is owed to those who have been wrongfully denied compensation for wrongs that caused them direct harm, and can be extended to others, such as their direct heirs, who are likewise affected by non-rectification. This opens the door to the endorsement of potentially extensive contemporary claims on behalf of the heirs of victims of wrongdoing. (shrink)

Current knowledge of the genetic, epigenetic, behavioural and symbolic systems of inheritance requires a revision and extension of the mid-twentieth-century, gene-based, 'Modern Synthesis' version of Darwinian evolutionary theory. We present the case for this by first outlining the history that led to the neo-Darwinian view of evolution. In the second section we describe and compare different types of inheritance, and in the third discuss the implications of a broad view of heredity for various aspects of evolutionary theory. We (...) end with an examination of the philosophical and conceptual ramifications of evolutionary thinking that incorporates multiple inheritance systems. (shrink)

In this paper, I argue that the increasing data about non-genetic inheritance requires the construction of a new conceptual framework that should complement the inclusive approaches already discussed in the literature. More precisely, I hold that this framework should be epistemologically relevant for evolutionary biologists in capturing the limits of extended inheritance and in reassessing the boundaries of biological systems that transmit traits to their offspring. I outline the first elements of an organizational account of extended inheritance. (...) In this account, the category of inherited factors is neither restricted to genes nor extended to stable resources related to trans-generational similarities. Instead, it includes persisting constitutive elements appearing as difference makers for heterogeneous organizational constraints, namely for heterogeneous constitutive parts whose specific role is to harness flows of matter and energy across generations of clearly delimited extended organized systems. This both inclusive and restrictive framework opens an additional way to apprehend how extended inheritance may affect evolutionary trajectories. (shrink)

This article provides a survey of key topics on just inheritance taxation. It does so by first presenting the main arguments in the debate. Here, I distinguish between arguments in the academic literature and the various arguments which have proven important in the public debate. Secondly, I outline four influential proposals when it comes to how inheritance should be taxed. Finally, I examine a recent controversy and point towards a number of themes that have not been sufficiently discussed.

Supersubstantivalism, the view that material objects are identical to their locations, has recently been defended in metaphysics and philosophy of physics. One of the most powerful arguments in its favour is the so-called argument from harmony. There is a certain harmony between material objects and their locations. Necessarily, if material object x is located at a spherical region, x is spherical. Necessarily, if material object x is located at region r, any part of x is located at a part of (...) r. Supersubstantivalism offers a straightforward explanation of such harmony. By contrast, dualism, the view that material objects are distinct from their locations, does not offer any explanation and should regard harmony principles as unexplained coincidences. In this paper I put forward a theory, which I shall call the ‘Inheritance Theory’, that does provide a straightforward explanation of harmony on behalf of dualists. (shrink)

This article examines how people of color can biologically inherit the deleterious effects of white racism. Drawing primarily on the field of epigenetics, I demonstrate how transgenerational racial disparities are in fact racist disparities that can be manifest physiologically, helping constitute the chemicals, hormones, cells, and fibers of the human body. Epigenetics can be used to demonstrate how white racism can have durable effects on the biological constitution of human beings that are not limited to the specific person who is (...) the target of white racism, but instead extend to that person's offspring. In this way, the field of epigenetics can help philosophers and others understand the transgenerational biological impact of social forces such as white racism. It reveals that the damage done by white racism is more extensive than critical philosophers of race might have realized, and also that interventions against white racism must address not just the economic, geographical, social, and psychological, but also the biological aspects of human existence. In particular, the article examines racist disparities in preterm birth rates and argues that the scope and significance of prenatal care for African American women must be expanded intergenerationally and include wide-scale forms of racial justice. (shrink)

Isabelle Stengers’ cosmopolitical proposal is an influential attempt by a European philosopher to transform the burdensome legacy of Western thought. Reconsidering her comprehensive engagement with the cosmology of the British mathematician and philosopher Alfred North Whitehead, this article reveals two concepts as foundational to Stengers’ cosmopolitics: civilization and commerce. While not usually associated with a critical political theory, in her development of what we call a commercial political ontology, Stengers explores the modes of inheriting these ostracized notions. By tracing the (...) genealogy of this political ontology back to Pericles’ first explicit defense of persuasion as a requisite for civilization, we argue that Pericles’ famous funeral oration provides the structure for Whitehead’s cosmology, and, ultimately, Stengers’ cosmopolitics. As such, we understand her cosmopolitical proposal as a dress rehearsal of a funeral eulogy for bourgeois society. (shrink)

Two enzymes involved in the synthesis of pyrimidine and purine nucleotides, CTP synthase (CTPS) and IMP dehydrogenase (IMPDH), can assemble into a single or very few large filaments called rods and rings (RR) or cytoophidia. Most recently, asymmetric cytoplasmic distribution of organelles during cell division has been described as a decisive event in hematopoietic stem cell fate. We propose that cytoophidia, which could be considered as membrane‐less organelles, may also be distributed asymmetrically during mammalian cell division as previously described for (...) Schizosaccharomyces pombe. Furthermore, because each type of nucleotide intervenes in distinct processes (e.g., membrane synthesis, glycosylation, and G protein‐signaling), alterations in the rate of synthesis of specific nucleotide types could influence cell differentiation in multiple ways. Therefore, we hypothesize that whether a daughter cell inherits or not CTPS or IMPDH filaments determines its fate and that this asymmetric inheritance, together with the dynamic nature of these structures enables plasticity in a cell population. (shrink)

Current knowledge of the genetic, epigenetic, behavioural and symbolic systems of inheritance requires a revision and extension of the mid-twentieth-century, gene-based, 'Modern Synthesis' version of Darwinian evolutionary theory. We present the case for this by first outlining the history that led to the neo-Darwinian view of evolution. In the second section we describe and compare different types of inheritance, and in the third discuss the implications of a broad view of heredity for various aspects of evolutionary theory. We (...) end with an examination of the philosophical and conceptual ramifications of evolutionary thinking that incorporates multiple inheritance systems. (shrink)

What might it mean to think of philosophy as being in the condition of modernism -- in which its relation to its own past, and hence its sense of its own future, has become an undismissable problem? If philosophy's hitherto-defining conventions can neither be taken for granted nor rejected, they must be put in question -- which menans re-evealuating the relation between the form and content of philosophical writing, rethinking the demands that such writing must place on its readers, and (...) reconceiving the nature of philosophy itself. Inheritance and Originality argues that the writings of Wittgenstein, Heidegger, and Kierkegaard are best understood as responsive to such questions, and as driven in consequence to strikingly similar reconceptions of language, reason, and understanding, doubt and scepticism, morality, and the structure of selfhood. Through detailed re-readings of these authors' most influential texts, as attentive to their specificity as to their family resemblances, Stephen Mulhall reorients our sense of the philosophical work each text aims to accomplish, to engender a critical dialogue betweeen them from which the elements of a new conception of philosophy might emerge, and to uncover that conception's indebtedness to certain fundamental theological preoccupations. (shrink)

What does it mean to think of philosophy in the condition of modernism, in which its relation to its past and future has become a relevant problem? This book argues that the writings of Wittgenstein, Heidegger, and Kierkegaard are best understood as responsive (each in their own way) to such questions. Through detailed analysis of these authors' most influential texts, Stephen Mulhall reorients our sense of the philosophical work each text aims to accomplish, engendering a critical dialogue between them from (...) which the elements of a new conception of philosophy might emerge. (shrink)

Heritable traits are predominantly encoded within genomic DNA, but it is now appreciated that epigenetic information is also inherited through DNA methylation, histone modifications, and small RNAs. Several examples of transgenerational epigenetic inheritance of traits have been documented in plants and animals. These include even the inheritance of traits acquired through the soma during the life of an organism, implicating the transfer of epigenetic information via the germline to the next generation. Small RNAs appear to play a significant (...) role in carrying epigenetic information across generations. This review focuses on how epigenetic information in the form of small RNAs is transmitted from the germline to the embryos through the gametes. We also consider how inherited epigenetic information is maintained across generations in a small RNA‐dependent and independent manner. Finally, we discuss how epigenetic traits acquired from the soma can be inherited through small RNAs. (shrink)

The theory of niche construction adds a second general inheritance system, ecological inheritance, to evolution . Ecological inheritance is the inheritance, via an external environment, of one or more natural selection pressures previously modified by niche-constructing organisms. This addition means descendant organisms inherit genes, and biotically transformed selection pressures in their environments, from their ancestors. The combined inheritance is called niche inheritance. Niche inheritance is used as a basis for classifying the multiple genetic (...) and non-genetic, inheritance systems currently being proposed as possibly significant in evolution . Implications of niche inheritance for the relationship between evolution and development are discussed. (shrink)

This paper examines the debate on gender equality which is considered by some groups to be in conflict with Q.S. An-Nisa [4]: ​​11. With a philosophical approach and referring to the concept of inheritance of Sa'id Ramadan al-Buthi in the _Kitab_ _al-Mar'ah Bayna Thughyan al-Nizam al-Gharbi wa Lata'if al-Tashri' al-Rabbani_, this paper tries to refute these allegations and offers a more gender-friendly interpretation. For al-Buthi, the verse has actually liberated women because the provisions are caused by the responsibilities imposed (...) by Islam on men as prospective husbands and not experienced by women. On the contrary, if women are empowered than men, that is a moral responsibility, not a _sharia_ responsibility. Thus, women have been given freedom by the _sharia_ in order to determine the choice to participate in bringing about stability in life, regardless of the existence of a condition of women more empowered than men that will not be the cause of changes in the provisions of _sharia_ concerning inheritance. (shrink)

Slavery harmed the slaves but not their descendants since slavery brought about their existence. The descendants gain the slaves’ claims via inheritance. However, collecting the inheritance-based claim runs into a number of difficulties. First, every descendant usually has no more than a portion of the slave’s claim because the claim is often divided over generations. Second, there are epistemic difficulties involving the ownership of the claim since it is unlikely that a descendant of a slave several generations removed (...) would have retained the claim of inheritance given the loss of wealth and disinheritance that often characterizes families. There are also problems in determining the amount of inheritance. This is in part because of the problems of calculating in the effects of offsets, especially crime-related offsets, which are owed by a significant portion of the descendants. Even if this inheritance claim can be established with sufficient confidence certain entities may not be asked to pay it. The federal government does not owe compensation since as a historical matter it permitted but did not cause enslavement. The beneficiaries of slavery do not owe compensation since merely receiving the benefit of an unjust activity does not by itself generate a debt of compensation. When combined these problems constitute an overwhelming case against reparations. (shrink)

Generalized Darwinism models cultural development as an evolutionary process, where traits evolve through variation, selection, and inheritance. Inheritance describes either a discrete unit’s transmission or a mixing of traits. In this article, we compare classical models of cultural evolution and generalized population dynamics with respect to blending inheritance. We identify problems of these models and introduce our model, which combines relevant features of both. Blending is implemented as success-based social learning, which can be shown to be an (...) optimal strategy. (shrink)

Inherited wealth will be of increasing importance in years to come. Yet inheritance taxation is unpopular, and part of this unpopularity is due to family concerns. Such taxation is seen by many as morally problematic because it is taken to violate important family values. In this article, we explore five family arguments against inheritance taxation: firstly, whether we have a right to benefit our children; secondly, whether it is a virtue to benefit one's children; thirdly, whether children have (...) a right to their parent's belongings, due to common ownership; fourthly, whether inheritance taxation may impair a vital sense of continuity and belonging; and lastly, an argument from incentives that appeals specifically to the relation between parents and children. We conclude that none of the arguments provide strong objections against a moderate or even a high inheritance tax rate, at least not when special provisions are made for things like family houses or farms. However, since the arguments all introduce concerns that should be assigned some weight, it would be unjust to abolish inheritance entirely. (shrink)

This paper examines a rarely-discussed argument for the right to bequeath wealth. This argument, popular among libertarians, asserts that opposition to the practice of inheritance is prone to over-generalize, such that opponents of inheritance cannot avoid condemning other uses of private property, like gift-giving. The argument is motivated by an interesting methodological claim, namely, that the morality of bequest ought to be evaluated from the perspective of the donor, and not evaluated in ways that invoke the effects of (...) bequest on the distribution of wealth. This paper argues that this donor-centric approach ultimately favors restricting the right of bequest. Specifically, I maintain that bequest generally carries a lower opportunity cost than other uses of property. Accordingly, inheritance tax is less coercive than other taxes, and bequest is less obviously as generous an act as gift giving. While the arguments made here will encourage traditional opponents of inheritance (such as egalitarians), I also suggest why they might be welcomed by at least some types of libertarian. (shrink)

In this paper, we adopt a physiological perspective in order to produce an intelligible overview of biological transmission in all its diversity. This allows us to put forward the analysis of transmission mechanisms, with the aim of complementing the usual focus on transmitted factors. We underline the importance of the structural, dynamical, and functional features of transmission mechanisms throughout organisms’ life cycles in order to answer to the question of what is passed on across generations, how and why. On this (...) basis, we propose a vision of biological transmission as networks of heterogeneous physiological mechanisms, not restricted to transmission mechanisms stricto sensu. They prove to be themselves suited candidates for evolutionary explanations. They are processes both necessary for evolution to happen and resulting themselves from evolution. This leads us to call for a strategy of endogenization to account for transmission, and more specifically inheritance, as evolved and evolving physiological mechanisms. (shrink)

Fifteen families cooperated in this study. Each consisted of father, mother and two or more children over 14 years of age. The recording of potentials was made by means of standard amplifiers and a Westinghouse oscillograph. An analysis of the records leads the author to conclude that, while no data which indicate a certain relationship between any members of a family on the basis of their electro-encephalographic patterns can be offered, it is justifiable to assume that the resemblances in the (...) patterns, if any exist, are not marked. The problem of whether or not patterns in brain potentials are inherited is not a closed one. Davis' work would definitely indicate that a hereditary factor does exist. Investigations of possible relationships between grandparents and grandchildren are indicated. (PsycINFO Database Record (c) 2016 APA, all rights reserved). (shrink)

This article focuses on the political 'effect' that Arendt wished to achieve with her 'old-fashioned storytelling'. It is argued that she inherited her concept of the 'redemptive power of narrative' (Benhabib) from Walter Benjamin. The close relationship of the two intuitively suggests an affinity between Arendt's concept of a 'fragmented past' and her 'storytelling' and Benjamin's conception of history and narrative. An attempt is made here to determine the amplitude and the meaning of this proximity. An account is provided of (...) Benjamin's and Arendt's shared belief that the past is fragmented and that only fragmented writing, mainly in the form of 'stories', had the capacity to be faithful to its 'ruins'. It is argued that for both Arendt and Benjamin, the purpose of this writing form was not to commemorate the dead, but to show their absence - their invisibility. It is suggested that Arendt and Benjamin held a similar conviction: that stories had the capacity to save the world. Key Words: Arendt • Benjamin • catastrophe • experience • fragmented past • imagination • remembrance • revelation • standpoint of the defeated • storytelling. (shrink)

The idea that natural selection can operate on cultural as well as genetic variation is central to recent theories of cultural evolution. This raises an overarching question: how much of traditional evolutionary theory, which was formulated in population-genetic terms, can survive intact once the possibility of cultural inheritance is taken into account? This question is addressed in relation to R. A. Fisher’s “fundamental theorem” of natural selection. Though Fisher’s theorem may appear to be an essentially genetic result, a version (...) of the theorem can be derived that applies to any evolving population, with an arbitrary inheritance mechanism. However, I argue that the biological significance of this “generalized” version of the fundamental theorem is less than that of the Fisherian original. (shrink)

A critical reflection on John Woods's new monograph, Truth in Fiction – Rethinking its Logic. I focus in particular on Woods’s world-inheritance thesis (what others have variously called ‘background,’ ‘the principle of minimal departure,’ and ‘the reality assumption,’ and which replaces Woods’s earlier ‘fill-conditions’) and its interplay with auctorial say-so, arguing that world-inheritance actually constrains auctorial say-so in ways Woods has not anticipated.

Review of Francoise Baylis, Altered Inheritance: CRISPR and the Ethics of Human Genome Editing (2019).

Inheritance diagrams are directed acyclic graphs with two types of connections between nodes: x → y and x ↛ y . Given a diagram D, one can ask the formal question of “is there a valid path between node x and node y?” Depending on the existence of a valid path we can answer the question “x is a y” or “x is not a y”. The answer to the above question is determined through a complex inductive algorithm on (...) paths between arbitrary pairs of points in the graph. This paper aims to simplify and interpret such diagrams and their algorithms. We approach the area on two fronts. Suggest reactive arrows to simplify the algorithms for the winning paths. We give a conceptual analysis of inheritance diagrams, and compare our analysis to the “small” and “big sets” of preferential and related reasoning. In our analysis, we consider nodes as information sources and truth values, direct links as information, and valid paths as information channels and comparisons of truth values. This results in an upward chaining, split validity, off-path preclusion inheritance formalism of a particularly simple type. We show that the small and big sets of preferential reasoning have to be relativized if we want them to conform to inheritance theory, resulting in a more cautious approach, perhaps closer to actual human reasoning. We will also interpret inheritance diagrams as theories of prototypical reasoning, based on two distances: set difference, and information difference. We will see that some of the major distinctions between inheritance formalisms are consequences of deeper and more general problems of treating conflicting information. It is easily seen that inheritance diagrams can also be analysed in terms of reactive diagrams - as can all argumentation systems. AMS Classification: 68T27, 68T30. (shrink)

Derrida and the Inheritance of Democracy provides a theoretically rich and accessible account of Derrida's political philosophy. Demonstrating the key role inheritance plays in Derrida’s thinking, Samir Haddad develops a general theory of inheritance and shows how it is essential to democratic action. He transforms Derrida’s well-known idea of "democracy to come" into active engagement with democratic traditions. Haddad focuses on issues such as hospitality, justice, normativity, violence, friendship, birth, and the nature of democracy as he reads (...) these deeply political writings. (shrink)

Whole-genome analysis and whole-exome analysis generate many more clinically actionable findings than traditional targeted genetic analysis. These findings may be relevant to research participants themselves as well as for members of their families. Though researchers performing genomic analyses are likely to find medically significant genetic variations for nearly every research participant, what they will find for any given participant is unpredictable. The ubiquity and diversity of these findings complicate questions about disclosing individual genetic test results. We outline an approach for (...) disclosing a select range of genetic results to the relatives of research participants who have died, developed in response to relatives? requests during a pilot study of large-scale medical genetic sequencing. We also argue that studies that disclose individual research results to participants should, at a minimum, passively disclose individual results to deceased participants? relatives. (shrink)

In the work of Henri Bergson and Martin Heidegger we find different responses to traditional ideas of ‘creation’. Bergson advances a philosophy of creation, wherein ‘creation’ is presented as the production of a ‘radical’ or ‘absolute’ novelty, not only in art, but in all forms of human experience and biological life. Heidegger, in contrast, comes to criticise ideas of ‘creation’ in art as the expression of an alienated ‘humanism’ and ‘subjectivism’ essential to the modern age. This paper illuminates this divergence (...) by showing how Bergson and Heidegger, despite appearances, grapple with the question of art-production – and with the attendant issues of inheritance and originality – in similar ways. It is only in recognising this proximity, I argue, that it is possible to perceive adequately what essentially distinguishes their approaches: Bergson’s conception of creation as a function of the will. (shrink)

The concept of biological inheritance has recently been extended so as to integrate, among other elements, parts of organisms’ environments. The literature refers to the trans-generational reconstruction of these parts in terms of environmental or ecological inheritance. This article’s main objective is to clarify the different meanings of "environmental inheritance," to underline so far unnoticed theoretical difficulties associated to this polysemous notion and to consequently argue that inheritance, even when extended, should be theoretically distinguished from trans-generational (...) environmental stability. After disentangling the different meanings of environmental inheritance, I underline that studies dealing with this concept place themselves in the wake of earlier contributions about biological environment and elaborate on the role of organisms in the determination of their relevant developmental and selective surroundings. This leads me to question the legitimacy of the category shift operated by niche inheritance proponents—from environment to inheritance—and to explain why the very concept of inherited environment shows important and so far unnoticed theoretical limitations. In this context, I assert the necessity to distinguish two related but different research programs: the construction of a finer-grained theory of environment and the elaboration of an extended theory of inheritance. (shrink)

The semantic concept of information is one of the most important, and one of the most problematical concepts in biology. I suggest a broad definition of biological information: a source becomes an informational input when an interpreting receiver can react to the form of the source (and variations in this form) in a functional manner. The definition accommodates information stemming from environmental cues as well as from evolved signals, and calls for a comparison between information‐transmission in different types of (...) class='Hi'>inheritance systems—the genetic, the epigenetic, the behavioral, and the cultural‐symbolic. This comparative perspective highlights the different ways in which information is acquired and transmitted, and the role that such information plays in heredity and evolution. Focusing on the special properties of the transfer of information, which are very different from those associated with the transfer of materials or energy, also helps to uncover interesting evolutionary effects and suggests better explanations for some aspects of the evolution of communication. (shrink)

In most computational ontologies, information inheritance is based on the taxonomic relation is_a. A given type inherits from other type only if the latter subsumes the former. We assume, however, that inheritance can be related, not only to the taxonomic relation, but also to the meronymic relationship between parts and wholes. The main aim of this paper is to organise upper-level ontologies associated with lexical information by taking into account part-whole subsumption. As we consider that parts may subsume (...) wholes under specific conditions, ontologies can be defined in terms of systems in which wholes inherit information from its parts. In this article, we describe how part-whole subsumption and, then, meronymic inheritance can be used to deal with type mismatch and metonymic interpretation of polysemous nouns. For this purpose, we attempt to merge old assumptions from both formal ontology and lexical semantics into a homogeneous framework. (shrink)

Hans-Georg Gadamer's philosophical hermeneutics - one of the seminal philosophies of the 20th century - has had a profound influence on a wide array of fields, including classical philology, theology, the philosophy of the social sciences, literary theory, philosophy of law, critical social theory and the philosophy of art. This collection expands on some of these areas and takes his hermeneutics into yet new fields including narrative medicine, biotechnology, the politics of memory, the philosophy of place and the non-verbal language (...) of the body. And, building on Gadamer's well-known discussions with Heidegger, Habermas and Derrida, Inheriting Gadamer sets him in dialogue with Mahatma Gandhi, Christine Korsgaard, Charles Mills and others. In these ways, the volume holds fast to a Gadamerian virtue: cultivating our important philosophical traditions while embracing the constant need to re-think their meaning in new circumstances and in relation to new knowledge. (shrink)

ABSTRACT Nietzsche's investigation into the origins of morality bears some striking similarities to contemporary investigations into human evolution. Here I investigate these similarities, using a comparison between Nietzsche's GM and Gould and Lewontin's influential “Spandrels” essay as a departure point. I argue that Nietzsche defends a proto-evolutionary psychology about morality, where the inheritance of enduring biological drives conflicts with our culturally evolved moral system. While Nietzsche's claims about the evolution of morality fit well within a Darwinian framework of natural (...) selection, his claims about our underlying biology do not. Those claims cohere better with the non-Darwinian views found in nineteenth-century German biology and embryology. (shrink)