BackgroundNew metrics have been developed to assess the impact of research and provide an indication of online media attention and data dissemination. We aimed to describe online media attention of articles evaluating cancer treatments and identify the factors associated with high online media attention.MethodsWe systematically searched MEDLINE via PubMed on March 1, 2015 for articles published during the first 6 months of 2014 in oncology and medical journals with a diverse range of impact factors, from 3.9 to 54.4, and selected (...) a sample of articles evaluating a cancer treatment regardless of study design. Altmetric Explorer was used to identify online media attention of selected articles. The primary outcome was media attention an article received online as measured by Altmetric score (i.e., number of mentions in online news outlets, science blogs and social media). Regression analysis was performed to investigate the factors associated with high media attention, and regression coefficients represent the logarithm of ratio of mean (RoM) values of Altmetric score per unit change in the covariate.ResultsAmong 792 articles, 218 (27.5%) received no online media attention (Altmetric score = 0). The median [Q1–Q3] Altmetric score was 2.0 [0.0–8.0], range 0.0–428.0. On multivariate analysis, factors associated with high Altmetric score were presence of a press release (RoM = 10.14, 95%CI [4.91–20.96]), open access to the article (RoM = 1.48, 95%CI [1.02–2.16]), and journal impact factor (RoM = 1.10, 95%CI [1.07–1.12]. As compared with observational studies, systematic reviews were not associated with high Altmetric score (RoM = 1.46, 95%CI [0.74–2.86]; P = 0.27), nor were RCTs (RoM = 0.65, 95%CI [0.41–1.02]; P = 0.059) and phase I/ii non-RCTs (RoM = 0.58, 95%CI [0.33–1.05]; P = 0.07). The articles with abstract conclusions favouring study treatments were not associated with high Altmetric score (RoM = 0.97, 95%CI [0.60–1.58]; P = 0.91).ConclusionsMost important factors associated with high online media attention were the presence of a press release and the journal impact factor. There was no evidence that study design with high level of evidence and type of abstract conclusion were associated with high online media attention. (shrink)

Ghosn, Margaret In the process leading up to the first Maronite diocesan assembly, a survey was sent to all Maronite parishes and schools in order to provide valuable feedback on what issues were foremost in the minds of the people. This was then to form the basis for the diocesan assembly to be held 12-14 April 2018. The survey sought to ascertain the demographics of those who participated, and parish attendance patterns and participation at parish and diocesan levels. It assessed (...) social services that were accessed, youth needs and family concerns, and offered opportunities for any further feedback. This article examines the responses of the survey and what they reveal about Maronite parishes across Australia, their areas of strength and areas needing improvement, the role of committees, and the needs and vision of the parishioners. (shrink)

Ghosn, Margaret Whether we acknowledge a God who sees all, or reject a God of history, there is meaning to be sought in the calamities of life. The fundamental question begins not with denying God, but with challenging the image of God. I argue for a God of all, despite evidence to the contrary, including prolific atheist arguments, the sweeping invasion of Islamic extremism, and apathetic attitudes of Christians today, and I do this firstly through a rebuttal of atheist arguments, (...) particularly in regard to morality and the role of science. Secondly, I use the book of Job as a reference point to discuss the God challenge, with a focus on human responsibility and the place of humans in the world. I propose that humans see the world evolving with purpose and that, in today's society, there is a God calling us to respond with conscious awareness. (shrink)

Ghosn, Mariam Predictive genetic testing Part 2 will examine the issues and ethical aspects that must be considered when adolescents below the age of majority make a request to undergo predictive genetic testing for Huntington's disease.

Ghosn, Mariam Huntington's disease (HD) is an inherited disorder. Sufferers usually develop symptoms in midlife between the ages of 30 and 50 years. HD causes neurodegeneration resulting in the progressive development of physical, cognitive and emotional symptoms. The impact on sufferers worsens over time with the final stage of the disease resulting in the need for professional assistance in a long-term care facility. More rarely HD develops in children and young adults, with less than 5% of HD sufferers being affected (...) by Juvenile HD. This article considers the ethical aspects of such testing. (shrink)

Ghosn, Mariam The causes of obesity are complex. Both our attitudes and lifestyles will need to change in order to successfully address this issue.

Ghosn, Mariam; Ford, Norman The adult stem cells are capable of self-renewal and are responsible for replenishing cells throughout an individual's lifetime, residing not only at embryonic stage but also in children and adults. The latest advancements and updates in adult stem cell technology demonstrate that it might be possible to generate stem cells for therapeutic uses without the creation or destruction of human embryos.

Ghosn, Mariam A seven-year $1 million dollar study conducted by Dr. M. Soffritti found that significant trend of increasing lymphoma and leukaemia incidence in female rats fed aspartame with a significant increase in the number of female rats affected at dosages of 20 mg/kg per day and upward, thus questioning aspartame's safety. However, the European Food Safety Authority's (EFSA's) Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) argued that there was not enough evidence (...) to conclude that aspartame causes an increased incidence of lymphomas and leukaemias, also arguing that the increase in the number of rats affected with lymphomas and leukaemias could be due to chronic respiratory infections of the rats used in the study. (shrink)

Taouk, Youssef; Ghosn, Margaret; Steel, Anthony; Butcher, Jude The Maronite Church, situated in the See of Antioch, had its origins in Syria, soon followed by its expansion to Lebanon. The Maronite Synod (2003-2006) distinguished aspects of the Maronite Catholic Church as: firstly, an Antiochene Syriac Church, with a special liturgical heritage; secondly, a Chalcedonian Church; thirdly, a Patriarchal Church with an ascetic and a monastic aspect; fourthly, a Church in full union with the Apostolic Roman See; fifthly, a Church incarnated (...) in her Lebanese and Eastern environment, and the Countries of Expansion. (shrink)