AbstractmRNA stability is increasingly recognized as being essential for controlling the expression of a wide variety of transcripts during neuronal development and synaptic plasticity. In this context, the role of AU‐rich elements (ARE) contained within the 3′ untranslated region (UTR) of transcripts has now emerged as key because of their high incidence in a large number of cellular mRNAs. This important regulatory element is known to significantly modulate the longevity of mRNAs by interacting with available stabilizing or destabilizing RNA‐binding proteins (...) (RBP). Thus, in parallel with the emergence of ARE, RBP are also gaining recognition for their pivotal role in regulating expression of a variety of mRNAs. In the nervous system, the member of the Hu family of ARE‐binding proteins known as HuD, has recently been implicated in multiple aspects of neuronal function including the commitment and differentiation of neuronal precursors as well as synaptic remodeling in mature neurons. Through its ability to interact with ARE and stabilize multiple transcripts, HuD has now emerged as an important regulator of mRNA expression in neurons. The present review is designed to provide a comprehensive and updated view of HuD as an RBP in the nervous system. Additionally, we highlight the role of HuD in multiple aspects of a neuron's life from early differentiation to changes in mature neurons during learning paradigms and in response to injury and regeneration. Finally, we describe the current state of knowledge concerning the molecular and cellular events regulating the expression and activity of HuD in neurons. BioEssays 28: 822–833, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

According to IOM, there have been 20.000 dead or missing migrants in the Mediterranean since 2014. According to the NGO United, there have been 44.000 dead people on the European borders since the beginning of 1990s. more than the 75% of these people goes missing in the sea. In Italy only a small part of retrieved bodies can be identified and sometimes repatriated. In most cases, the bodies are buried with no names in coastal cemeteries. In the face of the (...) expeditious disposal of the bodies, linked to public health issues and to the working of the devices that connotate the border regime, those communities that accommodate these corpses face the need to “integrate” someone else’s death in their own universe of sense thanks to specific practices of “hospitality” dedicated to the defunct. Through a project that maps buried migrants in the cemetery of Catania and in collaboration with the local committee of Red Cross and the municipality of Catania, since 2017 we have started, with the program Mecmi, an ethnography of the practices of body disposal and of burial rituals dedicated to more than 260 corpses. (shrink)

Le présent article décrit l’élaboration de la Charte de Lampedusa et analyse les bouleversements politiques et géopolitiques qui ont suivi son écriture, en parallèle avec les évolutions des dispositifs humanitaires-militaires de création, de gestion et de contrôle des frontières dans la zone euro-méditerranéenne. Les frontières sont considérées à partir de leur fonction de séparation ; une séparation qui n’est pas seulement géographique, mais également sociale, culturelle, économique, et qui l’est aussi à l’intérieur des limites nationales. Potentialités et limites de la (...) Charte sont ainsi évaluées à la lumière de sa capacité de représenter un cadre de référence encore actuel, aspirant à construire une vision alternative au modèle politique, économique, social et culturel prédominant en Europe ; un modèle qui aujourd’hui nécessite plus que jamais d’être complètement déstructuré. Cette vision alternative est imaginée à partir d’une conception des droits inclusive et « par le bas », qui s’oppose à leur histoire d’instrumentalisation institutionnelle, et à leur « réduction » dans le paradigme de l’humanitaire. (shrink)

This is a response to an article published inSociety & Animals in 2008 that argued for the existence of a “species identity disorder” in some furries. Species identity disorder is modeled on gender identity disorder, itself a highly controversial diagnosis that has been criticized for pathologizing homosexuality and transgendered people. This response examines the claims of the article and suggests that the typology it constructs is based on unexamined assumptions about what constitutes “human” identity and regulatory fictions of gender identity.

El Furry Fandom es una subcultura en torno al interés por animales o criaturas antropomórficas, pero apenas ha sido investigada su población hispanohablante, a pesar de la instigación de los medios de comunicación españoles reproduciendo estereotipos de los medios americanos. El artículo aborda cómo se construye la identidad furry en España y sus relaciones con la práctica del género (regulada sexualmente); así como el uso de jerga. El método consta de observación participante en foros y en entrevistas para análisis de (...) casos; lo cual permitió un análisis de contenidos diversos, repertorios interpretativos y un análisis crítico del discurso . Como conclusión, el furry fandom enmarca cuestiones feministas a partir de la metáfora del cyborg, tales como qué papel debe tener la ciencia, ideología sobre la naturaleza humana y la necesidad de coalición de identidades. (shrink)

This study explored the furry identity. Furries are humans interested in anthropomorphic art and cartoons. Some furries have zoomorphic tendencies. Furries often identify with, and/or assume, characteristics of a special/totem species of nonhuman animal. This research surveyed both furries and non-furry individuals attending a furry convention and a comparison group of college students . Furries commonly indicated dragons and various canine and feline species as their alternate-species identity; none reported a nonhuman-primate identity. Dichotomous responses to two key furry-identity questions produced (...) a two-by-two furry typology. These two independent dimensions are self-perception and species identity . One-quarter of the furry sample answered “yes” to both questions, placing them in the “Distorted Unattained” quadrant. This type of furry has certain characteristics paralleling gender-identity disorder. To explore this parallel, the furry typology, and the proposed construct of “Species Identity Disorder” needs further research. (shrink)

This article merges the ‘terminologies of social change’ from recognition theory and mediatization research to argue that the mediatization of society has eased and accelerated processes of what recognition theorist Axel Honneth calls individualization and social inclusion. This, however, cannot be understood unambiguously as moral progress. Thus, the first part of the article outlines the conceptualization of social change in Honneth’s recognition-theoretical framework, including the critique of recognition theory’s account of power, which problematizes Honneth’s inherent idea of moral progress. Considering (...) this critique, the article follows Douglas Giles’ suggestion that we must distinguish between affirmational and transformational struggles for recognition. The discussion is subsequently related to the conceptualization of social change in mediatization research, which shows that the closely interrelated phenomena of a social relocation of media and a re-orientation of the self help facilitate and constitute the individual’s increased possibilities, but also dependence, with respect to intersubjective recognition from peer groups in many contemporary societies. This provides the starting point for exemplifying how the conditions for affirmational and transformational recognition struggles, and thus individualization and social inclusion, have changed in a mediatized world. This exemplification draws primarily on an in-depth case study of mediated recognition in the lives of four young Danes aged 15 to 30 years with different subcultural identity positions. The main empirical illustrations involve the experiences of the 22-year-old hijabi football freestyler Maarika, who uses her Muslim identity actively on her social media channels to be a role model and to counter negative stereotypes of Muslims and female footballers. (shrink)

Winner of the Moonbeam Children's Animals/Pets Non-Fiction Gold Medal! A story about the fundamental connection between animals and people and how we can treat all of Earth's creatures with compassion and empathy. Furry polar bears, playful sea otters, slow sloths, prickly porcupines, and slimy snakes are just a few of the many animals we share our world with. And even though we might not look the same or have the same needs as our animal neighbors, we have more in common (...) with them than we might think. Our Animal Neighbors introduces children to the importance of treating all animals with the care and compassion they deserve. We all want to experience love, safety, and respect and this book is the first step to instilling those values at an early age. This planet is our home, and we should all be free to live a prosperous life regardless of whether we have hands, hooves, scales, or fur. “A serious message delivered with humor, simplicity, and charm makes this book an excellent purchase for families that value open-ended discussions. Also a good resource for classrooms and libraries that welcome diverse opinions and points of view.”—School Library Journal. (shrink)

This is a rebuttal to Fiona Probyn-Rapsey’s criticisms of the original furry research conducted in 2006 and published in 2008. Her focus on gender identity disorder misses the main point of the study, which was that it was the first empirical study to collect data scientifically and report findings on the furry fandom, an often misrepresented subculture.

We prove that the general scheme for physical theories that we have called semantic realism(SR) in some previous papers copes successfully with a number of EPR-like paradoxes when applied to quantum physics (QP). In particular, we consider the old arguments by Furry and Bohm- Aharonov and show that they are not valid within a SR framework. Moreover, we consider the Bell-Kochen-Specker und the Bell theorems that should prove that QP is inherently contextual and nonlocal, respectively, and show that they can (...) be invalidated in the SR approach. This removes the seeming contradiction between the basic assumptions of SR and QP, and proves that some problematic features that are usually attributed to QP, us contextuality and nonlocality, occur because of the adoption of a verificationist position, from one side, and from an insufficient adherence to the operational principles that have inspired QP itself, from the other side. (shrink)

This study explored the furry identity. Furries are humans interested in anthropomorphic art and cartoons. Some furries have zoomorphic tendencies. Furries often identify with, and/or assume, characteristics of a special/totem species of nonhuman animal. This research surveyed both furries and non-furry individuals attending a furry convention and a comparison group of college students. Furries commonly indicated dragons and various canine and feline species as their alternate-species identity; none reported a nonhuman-primate identity. Dichotomous responses to two key furry-identity questions produced a (...) two-by-two furry typology. These two independent dimensions are self-perception and species identity. One-quarter of the furry sample answered “yes” to both questions, placing them in the “Distorted Unattained” quadrant. This type of furry has certain characteristics paralleling gender-identity disorder. To explore this parallel, the furry typology, and the proposed construct of “Species Identity Disorder” needs further research. (shrink)

Notice that each of (1)–(4) is an instance of a more general pattern. For example, we could replace ‘black’ in (1) with any of a wide range of other adjectives such as ‘furry’ or ‘hungry’ or ‘three-legged’, without rendering the entailment invalid or any less obvious. Similarly, there are a number of verbs that occur in entailments parallel to (3): ‘Moe boiled the water; so the water boiled’; ‘Bart blew up the school; so the school blew up’; ‘Homer sank the (...) boat; so the boat sank’ and so on. (shrink)

Most people find it obvious that concepts like APPLE, DOG, WATER, CACTUS, SWIM, CHIRP, FURRY, and SMOOTH are acquired from perceptual experiences along with some kind of inferential procedure. Models of how these concepts are inferentially acquired, however, force the acquired concepts to be representationally complex, built from, and composed by, the more primitive representations. Since at least the time of Plato, philosophers and psychologists have struggled to find complex sets of representations that have the same meanings, definitionally or probabilistically, (...) as these concepts. For example, to think about the property-kind being gold is not the same as to think about the complex property-kind being yellowish & shiny & malleable.... I call this Fodor's Challenge: Find an acquisition process that is genuinely inferential and yields a concept that genuinely is one of these lexical concepts. Rather than continue the pursuit of a complex representation that has the same meaning as our concept GOLD. I offer a model on which many lexical concepts are acquired from perception and inference, without being built up from, and composed by, the representations involved. The model, Baptizing Meanings for Concepts, is inspired in part by Saul Kripke's baptism process for assigning meanings to linguistic terms. Many lexical concepts, according to the BMC, are acquired by inferring the presence a new property-kind, picking out the property-kind in terms of those perceptible features, and then assigning a simple mental term, a concept, for that property-kind. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Affect Attunement in the Caregiver-Infant Relationship and Across SpeciesExpanding the Ethical Scope of ErosCynthia WillettCompelling glimpses into the ethical capacities of our animal kin reveal new possibilities for ethical relationships encompassing humans with other animal species. Consider the remarkable report of a female bonobo in a British zoo who assists a bird found in her cage by retrieving the fallen bird, and spreading its wings so that this fellow (...) creature might fly away to its freedom. Or the report of a cat in a nursing home who curls up around dying elderly patients, and remains steadily by their side as they, unbeknownst to the medical personnel, pass away.1 Or of a sacred moment of silence by a stream for baboons in East Africa.2 Or of the ethics that spontaneously emerges among wolves at play.3 On the basis of extensive studies, biologist Frans de Waal argues that such anecdotes are far from rare, and that some core elements of moral understanding and compassion occur among a significant range of nonhuman as well as the human animal species. Apes, monkeys, and perhaps all nonhuman animals fail to display a distinctly human capacity for abstract moral reasoning. As de Waal (2006) remarks, it is difficult to tell (173–75). But our furry and feathery kin do without a doubt demonstrate rich elements of ethical response, and they often enough extend their moral concern to creatures beyond their own species. Of course, they will also bite each other’s heads off or eat their own young as well. But this is just to say that animals are neither natural [End Page 111] innocents nor savage brutes. Like us, they belong to what post-Nietzschean philosophers might frame, somewhat ironically, as a postlapsarian world of good and evil.What kind of philosophical approach could account for these postlapsarian genealogies of ethics? Biologists, primatologists, and anthropologists are drawing upon investigations of prosocial behavior to remap the boundaries of ethics, as for example in Isabelle Stengers’s call for cosmopolitical ecologies of relationships (2010, 33). Such a cosmopolitics aims to encompass our kin and kind from diverse species within the ethical boundaries of common worlds. Donna Haraway discovers an opening for Stengers’s ecology of relationships in the intimate encounters among co-evolving species, especially those she calls companion species (2008, 83). She argues, following Derrida, that the abstract reasoning processes of Stoic and Kantian cosmopolitan ethics remain closed to the participation of nonhuman animals as anything more than dependents, failing to observe the ways in which they act as companions, if not moral subjects. But then, what normative force might bind together an ethically attuned biosocial sphere that we as humans co-inhabit with other animal species?To explore this question, this essay takes its cues from well-established research on the responsive, preverbal connection of the human infant and adult caregiver (Bateson 1979; Trevarthen 1984; Stern 1985, 2010; Gibbs 2001, 2010; Hansen 2004; Anderson 2006; Papoulias and Callard 2010; Willett 1995, 2001). To this research we can add new animal studies (Smuts 1999, 2001; Fudge 2002; de Waal 2006, 2009; Bekoff 2007; Molnar 2008; Haraway 2008). These animal studies provide a basis for extending an “ethics of eros” with roots in Luce Irigaray, Michel Foucault, Enrique Dussel, Africana feminism, Freudo-Marxist critical theory, and Plato (for discussions of this tradition, see Bergoffen 1997; Huffer 2009; Willett 2001)—but reconfigured in terms of social bonds across multiple animal species. In this tradition of ethics, the lack of a cognitive-based moral subjectivity that can translate into human terms does not consign nonhuman species to a mute moral status. On the contrary, some more primordial basis for relationship and meaning may weave thin but substantial threads of a postmoral ethics across regions of the biosphere.Given the diverse modes of subjectivity among animal species, and even the lack of what we call a moral subject altogether in many species, neither ordinary modes of empathy nor of moral understanding go very far in forging multispecies social bonds. For this reason, we turn to research on “the attunement of affects” in the infant-caregiver relationship (Stern 1985). As we shall see, this... (shrink)

The Einstein-Podolsky-Rosen paradox as formulated in their original paper is critically examined. Their argument that quantum mechanics is incomplete is shown to be unsatisfactory on two important grounds. (i) The gedanken experiment proposed by Einstein, Podolsky, and Rosen is physically unrealizable, and consequently their argument is invalid as it stands. (ii) The basic assumptions of their argument are equivalent to the assumption that quantum mechanical systems are in fact describable by unique eigenfunctions of the operators corresponding to physical observables, independent (...) of any observation or measurement. Following an argument due to Furry, it is shown that this interpretation of quantum mechanics must lead to some physical predictions at variance with those of conventional quantum mechanics. A decisive experiment has been performed by Freedman and Clauser, which rules out this interpretation, and imposes severe restrictions on any alternative theory which incorporates the Einstein, Podolsky, and Rosen concept of physical reality. (shrink)

The aim of this paper is to offer a conceptual analysis of Weinberg's proof of the spin-statistics theorem by comparing it with Pauli's original proof and with the subsequent textbook tradition, which typically resorts to the dichotomy positive energy for half-integral spin particles/microcausality for integral-spin particles. In contrast to this tradition, Weinberg's proof does not directly invoke the positivity of the energy, but derives the theorem from the single relativistic requirement of microcausality. This seemingly innocuous difference marks an important change (...) in the conceptual basis of quantum physics. Its historical, theoretical, and conceptual roots are here reconstructed. The link between Weinberg's proof and Pauli's original is highlighted: Weinberg's proof turns out to do justice to Pauli's anti-Dirac lines of thought. The work of Furry and Oppenheimer is also surveyed as a “third way” between the textbook tradition established by Pauli and Weinberg's approach. (shrink)

“A flawless compendium of flaws.” —Alice Roberts, PhD, anatomist, writer, and presenter of The Incredible Human Journey The antidote to fuzzy thinking, with furry animals! Have you read (or stumbled into) one too many irrational online debates? Ali Almossawi certainly had, so he wrote An Illustrated Book of Bad Arguments! This handy guide is here to bring the internet age a much-needed dose of old-school logic (really old-school, a la Aristotle). Here are cogent explanations of the straw man fallacy, the (...) slippery slope argument, the ad hominem attack, and other common attempts at reasoning that actually fall short—plus a beautifully drawn menagerie of animals who (adorably) commit every logical faux pas. Rabbit thinks a strange light in the sky must be a UFO because no one can prove otherwise (the appeal to ignorance). And Lion doesn’t believe that gas emissions harm the planet because, if that were true, he wouldn’t like the result (the argument from consequences). Once you learn to recognize these abuses of reason, they start to crop up everywhere from congressional debate to YouTube comments—which makes this geek-chic book a must for anyone in the habit of holding opinions. (shrink)

Through his stunning photography, Wyman Meinzer chronicles the life of the coyote from a flea-covered, one-pound fuzzball whelp into a glistening, furry jewel that moves with fluid grace across the Texas plains. The coyote has become the symbol of western freedom in popular culture, and historically its range was limited to west of the Mississippi River. Yet now—in spite of a hundred-year effort to exterminate this wild canine—coyote howls can be heard from Los Angeles to the Bronx and from Alaska (...) to Costa Rica. Apart from the mythology, until recently little has been known about this intelligent, adaptable creature.As he did with The Roadrunner, Meinzer gives us a personal account of the years he spent observing and photographing this often maligned animal. Seasoned with humor and poignancy, his observations give us a glimpse into the heart and soul of this intelligent and adaptable native North American. (shrink)

Easy-to-follow step-by-step instructions take little ones through a grounding series of basic yoga poses. Simple, descriptive language invites young children to pretend to be a bear, moving their furry bodies into specific yoga poses designed to both energize and inspire bravery.

Applying machine learning algorithms to automatically infer relationships between concepts from large-scale collections of documents presents a unique opportunity to investigate at scale how human semantic knowledge is organized, how people use it to make fundamental judgments (“How similar are cats and bears?”), and how these judgments depend on the features that describe concepts (e.g., size, furriness). However, efforts to date have exhibited a substantial discrepancy between algorithm predictions and human empirical judgments. Here, we introduce a novel approach to generating (...) embeddings for this purpose motivated by the idea that semantic context plays a critical role in human judgment. We leverage this idea by constraining the topic or domain from which documents used for generating embeddings are drawn (e.g., referring to the natural world vs. transportation apparatus). Specifically, we trained state-of-the-art machine learning algorithms using contextually-constrained text corpora (domain-specific subsets of Wikipedia articles, 50+ million words each) and showed that this procedure greatly improved predictions of empirical similarity judgments and feature ratings of contextually relevant concepts. Furthermore, we describe a novel, computationally tractable method for improving predictions of contextually-unconstrained embedding models based on dimensionality reduction of their internal representation to a small number of contextually relevant semantic features. By improving the correspondence between predictions derived automatically by machine learning methods using vast amounts of data and more limited, but direct empirical measurements of human judgments, our approach may help leverage the availability of online corpora to better understand the structure of human semantic representations and how people make judgments based on those. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 63.3 (2002) 399-424 [Access article in PDF] Representation and the Body of Power in French Academic Painting Amy M. Schmitter [Figures] Reputation of power, is Power... Hobbes, Leviathan, Bk. I, ch. x Introduction It seems natural, even obvious, to distinguish between representations and what they are representations of. A picture of a dog is no more a dog than the word "dog" is (...) a furry, tail-wagging mammal. Nor are properties belonging to the object of a representation necessarily properties of the representation: a picture of a big dog need not be big, a picture of a dog that resembles Fido need not resemble Fido; even a picture of brown Fido need not be brown. And no number of pictures of Fido will sympathetically induce changes in Fido or any other dog. But however clear-cut this distinction may be when what is in question are pictorial references to ordinary, middle-sized material particulars such as dogs, it is much less clear in other cases. It is no violation of common-sense to consider "representations" of such things as gender norms or national identities or selves as non-neutral in the face of what they represent. The representations of gender norms, for example, can extend and enforce them, can change or undermine them, and may well lend a hand in constituting them in the first place.My theme here is a form of pictorial representation, one found in the theory and practice of that strain of French Academic painting under Louis XIV associated with Charles LeBrun. LeBrun held the titles of First Painter to the King and Director of the French Royal Academy of Painting, and the works I will examine were devoted to the royal power. That one effect of royal power is the ability to command resources and to cause the proliferation of representations, especially flattering representations, is no surprise. But I intend to suggest something stronger: not only did these Academic representations present an expenditure [End Page 399] of royal power, they were meant to embody and therefore extend royal power—even to constitute royal power. The view under examination does not simply collapse the common-sense distinction between signifying properties and what is signified; indeed those relations play an important role in one concept of representation modeled on language and written texts. But to this the academicians added another, more robust concept, one that does not distinguish clearly between the representation and its object.Implausible as this view may seem at first blush, I think it can prove genuinely explanatory: explanatory for thinking about pictorial representation, about how it can operate (on both its object and its viewer), and about its relation to power. But to see its explanatory value demands considering the nature and needs of state power. For unlike middle-sized material particulars, state power requires recognition to exist. Although that recognition need not be explicit, conscious, or voluntary, it must be widespread, and pictorial representations can be a powerful device for eliciting such recognition. Yet state power in general— or at least the particular form in question here—may demand that the constitutive role of recognition be disguised. Indeed many of the views and concepts of pictorial representation developed by the Academy reverse the dependence of power on recognition; they function in an ideology of representation. Nonetheless, I think that certain "formal," or structural, features of LeBrun's works can be explained in terms of how they elicit recognition and constitute this particular form of royal power. I make no claim that LeBrun's works must be explained so: for one, the royal power represented by LeBrun's works is long gone, and his representations do not now have any miraculous power to raise the dead. For any representations actually to operate as I suggest requires the support of a whole complex of institutions and activities committed to the care and feeding of state power. It is only because such a complex did exist that LeBrun's representations could have a recognizable object, i... (shrink)

In what follows I raise the question of Ariadne and Dionysus for Nietzsche, including the relative size of Ariadne’s ears, as Dionysus observes at the close of “Ariadne’s Lament” [Klage der Ariadne]. Nietzsche’s references to ears invoke not only Nietzsche’s “selective” concern with having the right ears but also the question of myth and genealogical context. Reading through myth is key not only in terms of the textual, lyric tradition but also painting and sculpture, including sarcophagi in antiquity. It makes (...) all the difference to ask, as Karl Kerényi cites Nietzsche as asking: Wer weiß …was Ariadne ist? And not less: who was she to Dionysus? To this extent, Nietzsche’s concern with ears, small and long, is less incidental or furry fetish than hermeneutic attunement. (shrink)

This essay presents an analysis of the conversational role of disambiguation, with special attention to disambiguating parentheticals such as 'bats, the furry animals, are not easy to find'. The essay proposes an enriched representation of conversational states as pairs of an interpretation function and standard common belief, it represents disambiguations within the ensuing framework, and, on the basis of these conceptual tools, it proposes a systematic picture of the updates achieved by disambiguating parentheticas.