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  1. Goldilocks and the two principles. A response to Gyngell et al.Peter Mills - 2019 - Journal of Medical Ethics 45 (8):524-525.
    In their paper Chris Gyngell, Hilary Bowman-Smart and Julian Savulescu offer a careful analysis of the Nuffield Council on Bioethics report, Genome Editing and Human Reproduction: social and ethical issues but they challenge us to go further still.i I want to suggest that, although their analysis is clear and accurate, its rather ‘molecular’ approach neglects the overall arc and orientation of the report. Furthermore, their conclusions about prospective parents’ reproductive obligations lack sensitivity to the proper evaluative context and offer littlein (...)
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  • The moral argument for heritable genome editing requires an inappropriately deterministic view of genetics.Rachel Horton & Anneke M. Lucassen - 2019 - Journal of Medical Ethics 45 (8):526-527.
    Gyngell and colleagues consider that the recent Nuffield Council report does not go far enough: heritable genome editing is not just justifiable in a few rare cases; instead, there is a moral imperative to undertake it. We agree that there is a moral argument for this, but in the real world it is mitigated by the fact that it is not usually possible to ensure a better life. We suggest that a moral imperative for HGE can currently only be concluded (...)
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  • Moral reasons to edit the human genome: picking up from the Nuffield report.Christopher Gyngell, Hilary Bowman-Smart & Julian Savulescu - 2019 - Journal of Medical Ethics 45 (8):514-523.
    In July 2018, the Nuffield Council of Bioethics released its long-awaited report on heritable genome editing. The Nuffield report was notable for finding that HGE could be morally permissible, even in cases of human enhancement. In this paper, we summarise the findings of the Nuffield Council report, critically examine the guiding principles they endorse and suggest ways in which the guiding principles could be strengthened. While we support the approach taken by the Nuffield Council, we argue that detailed consideration of (...)
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  • Commentary on ‘Moral reasons to edit the human genome’: this is not the moral imperative we are looking for.Sarah Chan - 2019 - Journal of Medical Ethics 45 (8):528-529.
    After reading Savulescu and colleagues,1 one ought to be in no doubt that human heritable genome editing is a ‘moral imperative’: to cure disease, reduce inequalities, improve public health and protect future generations. They make this argument repeatedly and in no uncertain terms. Yet are they right to do so? I am certainly not against developing HGE or exploring its possibilities. Instead, I aim to sound a cautionary note in relation to claims about its technological potential and how we frame (...)
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